{
    "uniprot_canonical_ac": "A2A5N3-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A2A5N3-1|A2A5N3_MOUSE Isoform 1 of Polyadenylate-binding protein  OS=Mus musculus OX=10090 GN=Pabpc1l PE=2 SV=1 CANONICAL=A2A5N3-1", 
        "length": 607, 
        "sequence": "MDTGGHGCSLSSLYVGDLHPDVTESMLYEMFSPIGNILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEVIKGQPIRIMWSHRDPGLRKSGMGNIFIKNLENSIDNKALYDTFSTFGSILSSKVVYNEHGSRGFGFVHFETHEAAQKAINTMNGMLLNDRKVFVGHFKSRQKREAELGARALGFTNIYVKNLHANVDEQRLQDLFSQFGNMQSVKVMRDSNGQSRGFGFVNFEKHEEAQKAVDHMNGKEVSGQLLYVGRAQKRAERQSELKRRFEQMKQERQNRYQGVNLYVKNLDDSINDERLKEVFSTYGVITSAKVMTESSHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYRRRPSHPVLSSFQQPTSYLLPAVPQSTAQAVYYSSGSITPMQPDPRWTAQPHGPPSTCPPAASVVQPLSTTQHPCIHLRGASQVSSQVPHTQRVVNIGTQTTGPGGEGSSIPGQLLVPHRGTSAVHSAHGVQESAVYVPGHQPLTVSMLAAAPLHEQKQMIGERLYSLIHDACAPLTGKITGMLLELDNLELLLLLESPESLHAKIEEAVAVLQVHREMESTDRN"
    }, 
    "uniprot_id": "A2A5N3_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                    "id": "A2A5N3", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/15475267", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "15475267"
                }
            ], 
            "title": "Gene discovery by microarray: identification of novel genes induced during growth factor-mediated muscle cell survival and differentiation.", 
            "journal": "Genomics", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
                    "id": "NP_001107551.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Kuninger D, Kuzmickas R, Peng B, Pintar JE, Rotwein P", 
            "date": "2004"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/15630085", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "15630085"
                }
            ], 
            "title": "An embryonic poly(A)-binding protein (ePAB) is expressed in mouse oocytes and early preimplantation embryos.", 
            "journal": "Proc. Natl. Acad. Sci. U.S.A.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                    "id": "A2A5N3", 
                    "database": "UniProtKB"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
                    "id": "NP_001107551.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Lalioti M.D., Steitz J.A., Seli E., Sakkas D., Flaherty S.M., Terzi N.", 
            "date": "2005"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/22814100", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "22814100"
                }
            ], 
            "title": "Epab and Pabpc1 are differentially expressed during male germ cell development.", 
            "journal": "Reproductive sciences (Thousand Oaks, Calif.)", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
                    "id": "NP_001107551.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Ozturk S, Guzeloglu-Kayisli O, Demir N, Sozen B, Ilbay O, Lalioti MD, Seli E", 
            "date": "2012"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/25370180", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "25370180"
                }
            ], 
            "title": "Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries.", 
            "journal": "Journal of assisted reproduction and genetics", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
                    "id": "NP_001107551.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Ozturk S, Sozen B, Demir N", 
            "date": "2015"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/30302808", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "30302808"
                }
            ], 
            "title": "Embryonic poly(A)-binding protein is differently expressed and interacts with the messenger RNAs in the mouse oocytes and early embryos.", 
            "journal": "Journal of cellular biochemistry", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
                    "id": "NP_001107551.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Uysal F, Ozturk S", 
            "date": "2019"
        }
    ], 
    "uniprot_ac": "A2A5N3", 
    "site_annotation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A5N3#A2A5N3-1", 
            "isoform_ac": "A2A5N3-1", 
            "locus": {
                "end_pos": 164025481, 
                "strand": "-", 
                "start_pos": 164050036, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000067715", 
                        "id": "ENSMUST00000067715", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000096701", 
                        "id": "ENSMUSP00000096701", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A2A5N3-1|A2A5N3_MOUSE Isoform 1 of Polyadenylate-binding protein  OS=Mus musculus OX=10090 GN=Pabpc1l PE=2 SV=1 CANONICAL=A2A5N3-1", 
                "length": 607, 
                "sequence": "MDTGGHGCSLSSLYVGDLHPDVTESMLYEMFSPIGNILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEVIKGQPIRIMWSHRDPGLRKSGMGNIFIKNLENSIDNKALYDTFSTFGSILSSKVVYNEHGSRGFGFVHFETHEAAQKAINTMNGMLLNDRKVFVGHFKSRQKREAELGARALGFTNIYVKNLHANVDEQRLQDLFSQFGNMQSVKVMRDSNGQSRGFGFVNFEKHEEAQKAVDHMNGKEVSGQLLYVGRAQKRAERQSELKRRFEQMKQERQNRYQGVNLYVKNLDDSINDERLKEVFSTYGVITSAKVMTESSHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYRRRPSHPVLSSFQQPTSYLLPAVPQSTAQAVYYSSGSITPMQPDPRWTAQPHGPPSTCPPAASVVQPLSTTQHPCIHLRGASQVSSQVPHTQRVVNIGTQTTGPGGEGSSIPGQLLVPHRGTSAVHSAHGVQESAVYVPGHQPLTVSMLAAAPLHEQKQMIGERLYSLIHDACAPLTGKITGMLLELDNLELLLLLESPESLHAKIEEAVAVLQVHREMESTDRN"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:381404", 
            "resource": "KEGG Pathway", 
            "id": "mmu:381404", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A5N3#function", 
            "annotation": "Binds the poly(A) tail of mRNA.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A5N3#function", 
                    "id": "A2A5N3", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
            "annotation": "In mature testis the highest levels of Epab are in spermatogonia, while Pabpc1 expression is detected in spermatocytes and round spermatids.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
                    "id": "NP_001107551.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
            "annotation": "These findings suggest that EPAB may predominantly play roles in translational regulation of the mRNAs during early oogenesis and folliculogenesis, but PABPC1 most likely perform these roles in the later terms of ovarian development along with EPAB", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
                    "id": "NP_001107551.1", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZAS7-1", 
            "protein_name": "Polyadenylate-binding protein", 
            "sequence": {
                "length": 607, 
                "sequence": "MDTRGHGCSLSSLYVGDLHPDVTEAMLYEMFSPIGTILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEMIKGQPIRIMWSHRDPGLRRSGMGNIFIKNLENSIDNKALYDTFSTFGSILSSKVVYNEHGSRGFGFVHFETHEAAQKAINTMNGMLLNDRKVFVGHFKSRQKREAELGARALGFTNIYVKNLRVDMDEQGLQDLFSQFGKTQSVKVMRDSNGQSRGFGFINFEKHEEAQKAVDHMNGKEVSGQLLYVGRAQKRAERQNELKRRFEQMKQERQNRYQGVNLYVKNLDDSINDDRLKEVFSTYGVITSAKVMTESSHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYRRRLSRSVLSSFQQPTSYLLPAVHQSTTQTMYYSSASIAPMQPDPRWTAQPHGPSSTCPPAASVVQPLSTAPHPCIHLSSASQASSQVPHTQRVVNIGTQTTGPGGEGSCIPGQPLLAHRGSSAVHSAHGVQESTVYVPGHQPLTVSMLDAAPLHEQKQMIGERLYSLIHDACAPLTGKITGMLLEMDNLELLLLLESPESLHAKIEEAVAVLKAHRAMESADSY"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A2A5N3/", 
                    "id": "A2A5N3", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
        "ac": "NP_001107551.1", 
        "name": "polyadenylate-binding protein 1-like", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "RNA binding", 
                        "id": "GO:0003723"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mRNA 3'-UTR binding", 
                        "id": "GO:0003730"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "poly(A) binding", 
                        "id": "GO:0008143"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008266", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "poly(U) RNA binding", 
                        "id": "GO:0008266"
                    }
                ], 
                "total": 4, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytosol", 
                        "id": "GO:0005829"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasmic stress granule", 
                        "id": "GO:0010494"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ribonucleoprotein complex", 
                        "id": "GO:1990904"
                    }
                ], 
                "total": 5, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", 
                        "pmid": "26134869", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "chromatin remodeling", 
                        "id": "GO:0006338"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006378", 
                        "pmid": "22621333", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mRNA polyadenylation", 
                        "id": "GO:0006378"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001556", 
                        "pmid": "26134869", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "oocyte maturation", 
                        "id": "GO:0001556"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048096", 
                        "pmid": "26134869", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "chromatin-mediated maintenance of transcription", 
                        "id": "GO:0048096"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051647", 
                        "pmid": "26134869", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A5N3", 
                                "id": "A2A5N3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus localization", 
                        "id": "GO:0051647"
                    }
                ], 
                "total": 5, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A5N3", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "1810053B01Rik; Epab"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A5N3", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Epab"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A5N3", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Pabpc1l"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A5N3", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Pabpc1l"
        }
    ], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000054582", 
            "id": "ENSMUSG00000054582", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/381404", 
            "id": "381404", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", 
            "id": "IPR000504", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002004", 
            "id": "IPR002004", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", 
            "id": "IPR003954", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006515", 
            "id": "IPR006515", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", 
            "id": "IPR012677", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", 
            "id": "IPR035979", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036053", 
            "id": "IPR036053", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:381404", 
            "id": "mmu:381404", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:1922908", 
            "id": "1922908", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/DHMNGKE/", 
            "id": "DHMNGKE", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1027234at2759", 
            "id": "1027234at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00076", 
            "id": "PF00076", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00658", 
            "id": "PF00658", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107551.1", 
            "id": "NP_001107551.1", 
            "database": "RefSeq"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 67433.0, 
        "chemical_mass": 67433.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A5N3", 
            "name": "Pabpc1l", 
            "locus": {
                "end_pos": 164050538, 
                "strand": "+", 
                "start_pos": 164025450, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000054582", 
                        "id": "ENSMUSG00000054582", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A5N3", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "PABP"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A5N3", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Polyadenylate-binding protein"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A5N3", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "embryonic poly(A)-binding protein"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A5N3", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "polyadenylate-binding protein 1-like"
        }
    ]
}