{
    "uniprot_canonical_ac": "A1L1K7-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A1L1K7-1|ACBG2_RAT Isoform 1 of Long-chain-fatty-acid--CoA ligase ACSBG2  OS=Rattus norvegicus OX=10116 GN=Acsbg2 PE=2 SV=1 CANONICAL=A1L1K7-1", 
        "length": 667, 
        "sequence": "MTQEKKAEDPDRGMDTTSAAPRLWSTHCDGEVLLRLSKHGPGHETPMTIPELFQESVERFGAYPALASKNGKKWDTLTFSQYYDVCRKAARSLIKLGLQRFHGVGILGFNSVEWVVAALGAILAGGLCVGIYATNSAEACQYVIKQANVNVLIVENDQQLQKILSIPPDKMETVKAIVQYRLPLMENSTNLYSWQDFMELGNAIPNIQLDRVILSQKANQCAVIIYTSGTTGSPKGVMLSHDNITWTAGAMAREIELIHVSGKQDTIVSYLPLSHIAAQLMDIWIPIKVGVLTFFAQPDALRGTLVYTLQEVKPTYFLGVPRVWEKMQDTIKENVAKSSNLRKKAFAWAKMLGLKVNTKKMLGKRDIPMNYRMAKALVFTKVRTSLGLDNCHTFFSGASPLSQDVSEFFLSLDIPIGEIYGMTECSGPHTVSCKSIYRVLSCGKVLNGCKNMLYKQNKDGVGEVCMWGRHVFMGYLGKEDATLEVLDEDGWLHSGDIGRLDSHDFLYITGRIKEVLITAGGENIWPIPIETLVKEKIPIISHAMLVGDKAKFLSMLLTLKCETDQMSGEPLDKLNLEAISFCQMLGSQAVTVSDILKIRDPVVYTAIQYGIDIVNQQAVSDSHRIRKWIILEKDFSIQGGELGPTSKLKRDLITQKYKAQIDNMYSS"
    }, 
    "uniprot_id": "ACBG2_RAT", 
    "enzyme_annotation": [
        {
            "ec": "6.2.1.15", 
            "activity": "ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA."
        }, 
        {
            "ec": "6.2.1.3", 
            "activity": ""
        }, 
        {
            "ec": "6.2.1.3", 
            "activity": "ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA."
        }
    ], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                    "id": "A1L1K7", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/16371355", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "16371355"
                }
            ], 
            "title": "The second member of the human and murine bubblegum family is a testis- and brainstem-specific acyl-CoA synthetase.", 
            "journal": "The Journal of biological chemistry", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073565.1", 
                    "id": "NP_001073565.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Pei Z, Jia Z, Watkins PA", 
            "date": "2006"
        }
    ], 
    "uniprot_ac": "A1L1K7", 
    "site_annotation": [
        {
            "end_pos": 189, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 187
        }, 
        {
            "end_pos": 245, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 243
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L1K7#A1L1K7-1", 
            "isoform_ac": "A1L1K7-1", 
            "locus": {
                "end_pos": 10174404, 
                "strand": "-", 
                "start_pos": 10201206, 
                "chromosome": "9", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000074555", 
                        "id": "ENSRNOT00000074555", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000066937", 
                        "id": "ENSRNOP00000066937", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A1L1K7-1|ACBG2_RAT Isoform 1 of Long-chain-fatty-acid--CoA ligase ACSBG2  OS=Rattus norvegicus OX=10116 GN=Acsbg2 PE=2 SV=1 CANONICAL=A1L1K7-1", 
                "length": 667, 
                "sequence": "MTQEKKAEDPDRGMDTTSAAPRLWSTHCDGEVLLRLSKHGPGHETPMTIPELFQESVERFGAYPALASKNGKKWDTLTFSQYYDVCRKAARSLIKLGLQRFHGVGILGFNSVEWVVAALGAILAGGLCVGIYATNSAEACQYVIKQANVNVLIVENDQQLQKILSIPPDKMETVKAIVQYRLPLMENSTNLYSWQDFMELGNAIPNIQLDRVILSQKANQCAVIIYTSGTTGSPKGVMLSHDNITWTAGAMAREIELIHVSGKQDTIVSYLPLSHIAAQLMDIWIPIKVGVLTFFAQPDALRGTLVYTLQEVKPTYFLGVPRVWEKMQDTIKENVAKSSNLRKKAFAWAKMLGLKVNTKKMLGKRDIPMNYRMAKALVFTKVRTSLGLDNCHTFFSGASPLSQDVSEFFLSLDIPIGEIYGMTECSGPHTVSCKSIYRVLSCGKVLNGCKNMLYKQNKDGVGEVCMWGRHVFMGYLGKEDATLEVLDEDGWLHSGDIGRLDSHDFLYITGRIKEVLITAGGENIWPIPIETLVKEKIPIISHAMLVGDKAKFLSMLLTLKCETDQMSGEPLDKLNLEAISFCQMLGSQAVTVSDILKIRDPVVYTAIQYGIDIVNQQAVSDSHRIRKWIILEKDFSIQGGELGPTSKLKRDLITQKYKAQIDNMYSS"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:301120", 
            "resource": "KEGG Pathway", 
            "id": "rno:301120", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-75876", 
            "resource": "Reactome", 
            "id": "R-RNO-75876", 
            "name": "Synthesis of very long-chain fatty acyl-CoAs"
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L1K7#function", 
            "annotation": "Catalyzes the conversion of fatty acids such as long chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L1K7#function", 
                    "id": "A1L1K7", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q2XU92-1", 
            "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", 
            "sequence": {
                "length": 667, 
                "sequence": "MTQEKKAEDLERGTDATSAVPRLWSTHCDGEVLLRLSKHGPGHETPMTIPELFQESAERFSAYPALASKNGKKWDTLTFSQYYEMCRKAAKSLIKLGLQRFQCVGILGFNSVEWVVTALGTILAGGLCVGIYATNSAEACQYVIQQANVSILIVENDQQLQKILLIPPDKMETVKAIVQYKLPLMESMANLYSWNDFMELGNDIPNIQLDRVILSQKANQCAVILYTSGTTGTPKGVLLSHDNITWTAGAMSQEMEINRVSGKQNTIVSYLPLSHIAAQLTDIWIPIKIGALTFFAQPDALRGTLVYTLQEVKPTLFMGVPRIWEKMQDTIKENVARSSRLRKKAFAWAKMLGLKVNTKRMLGKRDIPMNYRMAKALVFAKVRTSLGLDNCHAFFSSASPLSQDVSEFFLSLDIPIGEIYGMSECSGPHTVSNKSVYRVLSCGKVLSGCKNMLYNQNKEGVGEVCMWGRHVFMGYLNKEEATLEALDENGWLHSGDIGRLDSHDFLYITGRIKEILITAGGENVSPIPIETLVKEKIPIISHAMLVGDKAKFLCMLLTLKCETDRKSGEPLNKLSVEAKSFCQMLGSQATTVSDILKSRDQVVYTAIQYGIDIVNQQAMSDSHRIRKWIILEKDFSIQGGELGPTSKLKRSVITQKYKAQIDSMYLS"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/57133", 
                    "id": "57133", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A1L1K7/", 
                    "id": "A1L1K7", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q5FVE4-1", 
            "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", 
            "sequence": {
                "length": 666, 
                "sequence": "MTGTPKTQEGAKDLEVDMNKTEVTPRLWTTCRDGEVLLRLSKHGPGHETPMTIPEFFRESVNRFGTYPALASKNGKKWEILNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLEPLKAIIQYRLPMKKNNNLYSWDDFMELGRSIPDTQLEQVIESQKANQCAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKLTDKHETVVSYLPLSHIAAQMMDIWVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEFFLSLDIPIGELYGLSESSGPHTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEICLWGRHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISNAMLVGDKLKFLSMLLTLKCEMNQMSGEPLDKLNFEAINFCRGLGSQASTVTEIVKQQDPLVYKAIQQGINAVNQEAMNNAQRIEKWVILEKDFSIYGGELGPMMKLKRHFVAQKYKKQIDHMYH"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/57133", 
                    "id": "57133", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073565.1", 
        "ac": "NP_001073565.1", 
        "name": "long-chain-fatty-acid--CoA ligase ACSBG2", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ATP binding", 
                        "id": "GO:0005524"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "acyl-CoA hydrolase activity", 
                        "id": "GO:0047617"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004467", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "long-chain fatty acid-CoA ligase activity", 
                        "id": "GO:0004467"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102391", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "decanoate-CoA ligase activity", 
                        "id": "GO:0102391"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003996", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "acyl-CoA ligase activity", 
                        "id": "GO:0003996"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047676", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "arachidonate-CoA ligase activity", 
                        "id": "GO:0047676"
                    }
                ], 
                "total": 6, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mitochondrion", 
                        "id": "GO:0005739"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytosol", 
                        "id": "GO:0005829"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "membrane", 
                        "id": "GO:0016020"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007275", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "multicellular organism development", 
                        "id": "GO:0007275"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "spermatogenesis", 
                        "id": "GO:0007283"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1K7", 
                                "id": "A1L1K7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cell differentiation", 
                        "id": "GO:0030154"
                    }
                ], 
                "total": 3, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L1K7", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Acsbg2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L1K7", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Acsbg2"
        }
    ], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000045947", 
            "id": "ENSRNOG00000045947", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/301120", 
            "id": "301120", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", 
            "id": "IPR000873", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020845", 
            "id": "IPR020845", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", 
            "id": "IPR042099", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:301120", 
            "id": "rno:301120", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/PKYVENK/", 
            "id": "PKYVENK", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=806831at2759", 
            "id": "806831at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00501", 
            "id": "PF00501", 
            "database": "Pfam"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A1L1K7", 
            "id": "PR_A1L1K7", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-75876", 
            "id": "R-RNO-75876", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073565.1", 
            "id": "NP_001073565.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1588580", 
            "id": "1588580", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 74266.0, 
        "chemical_mass": 74266.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L1K7", 
            "name": "Acsbg2", 
            "locus": {
                "end_pos": 10203460, 
                "strand": "+", 
                "start_pos": 10172832, 
                "chromosome": "9", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000045947", 
                        "id": "ENSRNOG00000045947", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L1K7", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "6.2.1.15"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L1K7", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "6.2.1.3"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L1K7", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Acyl-CoA synthetase bubblegum family member 2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L1K7", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Arachidonate--CoA ligase ACSBG2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L1K7", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Long-chain-fatty-acid--CoA ligase ACSBG2"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L1K7", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "bubblegum-related acyl-CoA synthetase 2; arachidonate--CoA ligase ACSBG2"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L1K7", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "long-chain-fatty-acid--CoA ligase ACSBG2"
        }
    ]
}