{
    "uniprot_canonical_ac": "A1L108-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A1L108-1|ARP5L_RAT Isoform 1 of Actin-related protein 2/3 complex subunit 5-like protein  OS=Rattus norvegicus OX=10116 GN=Arpc5l PE=1 SV=2 CANONICAL=A1L108-1", 
        "length": 153, 
        "sequence": "MARNTLSSRFRRVDIDEFDENKFVDEHEEAAAASGEPGPDPCEVDGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGIVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV"
    }, 
    "uniprot_id": "ARP5L_RAT", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L108", 
                    "id": "A1L108", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/20458337", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "20458337"
                }
            ], 
            "title": "MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.", 
            "journal": "Immunology and cell biology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032856.2", 
                    "id": "NP_001032856.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W", 
            "date": "2010"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/21423176", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "21423176"
                }
            ], 
            "title": "Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for beta-Pix in negative regulation of focal adhesion maturation.", 
            "journal": "Nature cell biology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032856.2", 
                    "id": "NP_001032856.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM", 
            "date": "2011"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "22673903"
                }
            ], 
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", 
            "journal": "Nat. Commun.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L108", 
                    "id": "A1L108", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", 
            "date": "2012"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/8889548", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "8889548"
                }
            ], 
            "title": "Normalization and subtraction: two approaches to facilitate gene discovery.", 
            "journal": "Genome Res.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L108", 
                    "id": "A1L108", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Lennon G., Soares M.B., Bonaldo M.F.", 
            "date": "1996"
        }
    ], 
    "uniprot_ac": "A1L108", 
    "site_annotation": [
        {
            "end_pos": 124, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 122
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L108#A1L108-1", 
            "isoform_ac": "A1L108-1", 
            "locus": {
                "end_pos": 23301514, 
                "strand": "-", 
                "start_pos": 23308326, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000019405", 
                        "id": "ENSRNOT00000019405", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000019405", 
                        "id": "ENSRNOP00000019405", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A1L108-1|ARP5L_RAT Isoform 1 of Actin-related protein 2/3 complex subunit 5-like protein  OS=Rattus norvegicus OX=10116 GN=Arpc5l PE=1 SV=2 CANONICAL=A1L108-1", 
                "length": 153, 
                "sequence": "MARNTLSSRFRRVDIDEFDENKFVDEHEEAAAASGEPGPDPCEVDGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGIVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L108#A1L108-2", 
            "isoform_ac": "A1L108-2", 
            "locus": {}, 
            "sequence": {
                "header": "sp|A1L108-2|ARP5L_RAT Isoform 2 of Actin-related protein 2/3 complex subunit 5-like protein  OS=Rattus norvegicus OX=10116 GN=Arpc5l PE=1 SV=2 CANONICAL=A1L108-1", 
                "length": 101, 
                "sequence": "MLRAFHAALRNSPINTKNQAVKERAQGIVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:296710", 
            "resource": "KEGG Pathway", 
            "id": "rno:296710", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L108#function", 
            "annotation": "May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L108#function", 
                    "id": "A1L108", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9BPX5-1", 
            "protein_name": "Actin-related protein 2/3 complex subunit 5-like protein", 
            "sequence": {
                "length": 153, 
                "sequence": "MARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGVDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/36463", 
                    "id": "36463", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A1L108/", 
                    "id": "A1L108", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "Q9D898-1", 
            "protein_name": "Actin-related protein 2/3 complex subunit 5-like protein", 
            "sequence": {
                "length": 153, 
                "sequence": "MARNTLSSRFRRVDIDEFDENKFVDEHEEAAAAAGEPGPDPCEVDGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/36463", 
                    "id": "36463", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A1L108/", 
                    "id": "A1L108", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032856.2", 
        "ac": "NP_001032856.2", 
        "name": "actin-related protein 2/3 complex subunit 5-like protein", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L108", 
                                "id": "A1L108", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "actin filament binding", 
                        "id": "GO:0051015"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L108", 
                                "id": "A1L108", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005885", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L108", 
                                "id": "A1L108", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Arp2/3 protein complex", 
                        "id": "GO:0005885"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L108", 
                                "id": "A1L108", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "glutamatergic synapse", 
                        "id": "GO:0098978"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L108", 
                                "id": "A1L108", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cell migration", 
                        "id": "GO:0016477"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L108", 
                                "id": "A1L108", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Arp2/3 complex-mediated actin nucleation", 
                        "id": "GO:0034314"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L108", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Arpc5l"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L108", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Arpc5l"
        }
    ], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000014317", 
            "id": "ENSRNOG00000014317", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/296710", 
            "id": "296710", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A1L108*", 
            "id": "A1L108", 
            "database": "IntAct"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006789", 
            "id": "IPR006789", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR030075", 
            "id": "IPR030075", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036743", 
            "id": "IPR036743", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:296710", 
            "id": "rno:296710", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/KEVHMAT/", 
            "id": "KEVHMAT", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1565115at2759", 
            "id": "1565115at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12644", 
            "id": "PTHR12644", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12644:SF2", 
            "id": "PTHR12644:SF2", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF04699", 
            "id": "PF04699", 
            "database": "Pfam"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A1L108", 
            "id": "PR_A1L108", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032856.2", 
            "id": "NP_001032856.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1308867", 
            "id": "1308867", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [
        {
            "residue": "Ser", 
            "position": "64", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", 
                    "id": "22673903", 
                    "database": "PubMed"
                }
            ], 
            "kinase_uniprot_canonical_ac": "Q703I1-1", 
            "kinase_gene_name": "Oser1"
        }, 
        {
            "residue": "Ser", 
            "position": "64", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L108", 
                    "id": "A1L108", 
                    "database": "UniProtKB"
                }
            ], 
            "kinase_uniprot_canonical_ac": "", 
            "kinase_gene_name": ""
        }
    ], 
    "mass": {
        "monoisotopic_mass": 17010.0, 
        "chemical_mass": 17010.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L108", 
            "name": "Arpc5l", 
            "locus": {
                "end_pos": 23309072, 
                "strand": "+", 
                "start_pos": 23301455, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000014317", 
                        "id": "ENSRNOG00000014317", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L108", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "3 complex 16 kDa subunit 2"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L108", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "ARC16-2; arp2/3 complex 16 kDa subunit 2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L108", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "ARC16-2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L108", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Actin-related protein 2/3 complex subunit 5-like protein"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L108", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "actin-related protein 2/3 complex subunit 5-like protein"
        }
    ]
}