{
    "uniprot_canonical_ac": "A1A5S2-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A1A5S2-1|A1A5S2_RAT Isoform 1 of CXXC finger protein 1  OS=Rattus norvegicus OX=10116 GN=Cxxc1 PE=1 SV=1 CANONICAL=A1A5S2-1", 
        "length": 660, 
        "sequence": "MEGDGSDLEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKCRERDGSERDGSEPRDEGGGRKRPASDPELQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSEALPRPRRPPPTQQQPQQSQKLGRIREDEGTVLSSVVKEPPEATATPEPLSDEDLALDPDLYQDFCAGAFDDHVPWMSDAEESPFLDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRAAQPGSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEENNENDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR"
    }, 
    "uniprot_id": "A1A5S2_RAT", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1A5S2", 
                    "id": "A1A5S2", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/17998332", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "17998332"
                }
            ], 
            "title": "Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.", 
            "journal": "Molecular and cellular biology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073166.1", 
                    "id": "NP_001073166.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Lee JH, Skalnik DG", 
            "date": "2008"
        }
    ], 
    "uniprot_ac": "A1A5S2", 
    "site_annotation": [
        {
            "end_pos": 481, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 479
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A1A5S2#A1A5S2-1", 
            "isoform_ac": "A1A5S2-1", 
            "locus": {
                "end_pos": 70192862, 
                "strand": "-", 
                "start_pos": 70197591, 
                "chromosome": "18", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000020472", 
                        "id": "ENSRNOT00000020472", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000020472", 
                        "id": "ENSRNOP00000020472", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A1A5S2-1|A1A5S2_RAT Isoform 1 of CXXC finger protein 1  OS=Rattus norvegicus OX=10116 GN=Cxxc1 PE=1 SV=1 CANONICAL=A1A5S2-1", 
                "length": 660, 
                "sequence": "MEGDGSDLEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKCRERDGSERDGSEPRDEGGGRKRPASDPELQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSEALPRPRRPPPTQQQPQQSQKLGRIREDEGTVLSSVVKEPPEATATPEPLSDEDLALDPDLYQDFCAGAFDDHVPWMSDAEESPFLDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRAAQPGSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEENNENDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:291440", 
            "resource": "KEGG Pathway", 
            "id": "rno:291440", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9CWW7-1", 
            "protein_name": "CXXC-type zinc finger protein 1", 
            "sequence": {
                "length": 660, 
                "sequence": "MEGDGSDLEPPDAGDDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKCRERDGSERAGSEPRDEGGGRKRPASDPELQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHHQQQQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSEALPRPRRPPPTQQQPQQSQKLGRIREDEGTVLSSVVKEPPEATATPEPLSDEDLALDPDLYQDFCAGAFDDHGLPWMSDAEESPFLDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRAAQPGSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEENNENDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/32221", 
                    "id": "32221", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A1A5S2/", 
                    "id": "A1A5S2", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q9P0U4-1", 
            "protein_name": "CXXC-type zinc finger protein 1", 
            "sequence": {
                "length": 656, 
                "sequence": "MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/32221", 
                    "id": "32221", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073166.1", 
        "ac": "NP_001073166.1", 
        "name": "CXXC-type zinc finger protein 1", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", 
                        "pmid": "21814290", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5S2", 
                                "id": "A1A5S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "proximal promoter sequence-specific DNA binding", 
                        "id": "GO:0000987"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5S2", 
                                "id": "A1A5S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "zinc ion binding", 
                        "id": "GO:0008270"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5S2", 
                                "id": "A1A5S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "histone methyltransferase activity (H3-K4 specific)", 
                        "id": "GO:0042800"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045322", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5S2", 
                                "id": "A1A5S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "unmethylated CpG binding", 
                        "id": "GO:0045322"
                    }
                ], 
                "total": 4, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5S2", 
                                "id": "A1A5S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytosol", 
                        "id": "GO:0005829"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5S2", 
                                "id": "A1A5S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nuclear speck", 
                        "id": "GO:0016607"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5S2", 
                                "id": "A1A5S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nuclear matrix", 
                        "id": "GO:0016363"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5S2", 
                                "id": "A1A5S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Set1C/COMPASS complex", 
                        "id": "GO:0048188"
                    }
                ], 
                "total": 4, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5S2", 
                                "id": "A1A5S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of transcription, DNA-templated", 
                        "id": "GO:0045893"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1A5S2", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Cxxc1"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5S2", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Cxxc1"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5S2", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "rCG_41744"
        }
    ], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000014614", 
            "id": "ENSRNOG00000014614", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/291440", 
            "id": "291440", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", 
            "id": "IPR001965", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002857", 
            "id": "IPR002857", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", 
            "id": "IPR011011", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", 
            "id": "IPR019786", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", 
            "id": "IPR019787", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR022056", 
            "id": "IPR022056", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR037869", 
            "id": "IPR037869", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:291440", 
            "id": "rno:291440", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/ENAPLYC/", 
            "id": "ENAPLYC", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=463371at2759", 
            "id": "463371at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46174", 
            "id": "PTHR46174", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00628", 
            "id": "PF00628", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF02008", 
            "id": "PF02008", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF12269", 
            "id": "PF12269", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073166.1", 
            "id": "NP_001073166.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1310755", 
            "id": "1310755", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 76273.0, 
        "chemical_mass": 76273.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A1A5S2", 
            "name": "Cxxc1", 
            "locus": {
                "end_pos": 70197867, 
                "strand": "+", 
                "start_pos": 70192493, 
                "chromosome": "18", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000014614", 
                        "id": "ENSRNOG00000014614", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A1A5S2", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "CXXC finger 1 (PHD domain), isoform CRA_b"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5S2", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "CXXC finger 1 (PHD domain)"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5S2", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "CXXC finger protein 1"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1A5S2", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "CXXC-type zinc finger protein 1"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1A5S2", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "cpG-binding protein; CXXC finger 1 (PHD domain)"
        }
    ]
}