{ "uniprot_canonical_ac": "A0JPN2-1", "ptm_annotation": [], "sequence": { "header": "sp|A0JPN2-1|S39A4_RAT Isoform 1 of Zinc transporter ZIP4 OS=Rattus norvegicus OX=10116 GN=Slc39a4 PE=2 SV=1 CANONICAL=A0JPN2-1", "length": 656, "sequence": "MLPKSLTQGLLLAMLVGTAAMVQPYHLLSLLTSGQGALDRTALDGLLNTLVARVHCTDGPCEKCLSVETALALGKPDKPQLAPESVLESRYITYLSAAAALYLNDPEKTCKDIRAGLLASHVDDYLAKLESPEAMTLGLSQLLQKIEAHDASQPTREETCVDVPQLLEEAEEAGVSRSPGLVLTALLDHVLNGSCFQGLPSPQYFVDFVFRQLSSKPRNITLPELEDLMHHLGVGGEDHSDHGDHVDHSHLDREANHQDSELHATHNSSSSVWDTLCLSAKDVMAVYGLSEEAGVSPQAWAQLTPALVQQQLSEACSSSPIIHVQDQLSQAERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDALLHLIPKVLGLHTHSGEVHSHEEESIGGQSTWRLLAVLGGFYIFFLFESFFNLLLPRDQDHEKDGPCSHGGHSHGISLQLSPSNLRQSKQPHESSRSDLVTEETPELLNPDTRRLRAELRMLPYLITLGDAVHNFADGLAVGAAFSSTWKTGLATSLAVFCHELPHELGDFAALLHAGLTVKRALLLNLASALTAFAGLYVALAVGVGEEGETWILAVATGLFLYVALCDMLPAMMNVRDQRPWLLFLLHNVGLLGGWTILLLLSLYEDSITF" }, "uniprot_id": "S39A4_RAT", "enzyme_annotation": [], "glycation": [], "keywords": [ "glycoprotein", "predicted.uniprotkb_gly" ], "species": [ { "common_name": "Rat", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "id": "A0JPN2", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/12068297", "type": [ "PubMed" ], "id": "12068297" } ], "title": "Identification of SLC39A4, a gene involved in acrodermatitis enteropathica.", "journal": "Nature genetics", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" } ], "authors": "Kury S, Dreno B, Bezieau S, Giraudet S, Kharfi M, Kamoun R, Moisan JP", "date": "2002" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/12801924", "type": [ "PubMed" ], "id": "12801924" } ], "title": "The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice.", "journal": "The Journal of biological chemistry", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" } ], "authors": "Dufner-Beattie J, Wang F, Kuo YM, Gitschier J, Eide D, Andrews GK", "date": "2003" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/14612438", "type": [ "PubMed" ], "id": "14612438" } ], "title": "Zn2+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane.", "journal": "The Journal of biological chemistry", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" } ], "authors": "Kim BE, Wang F, Dufner-Beattie J, Andrews GK, Eide DJ, Petris MJ", "date": "2004" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/15358787", "type": [ "PubMed" ], "id": "15358787" } ], "title": "The adaptive response to dietary zinc in mice involves the differential cellular localization and zinc regulation of the zinc transporters ZIP4 and ZIP5.", "journal": "The Journal of biological chemistry", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" } ], "authors": "Dufner-Beattie J, Kuo YM, Gitschier J, Andrews GK", "date": "2004" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/19530166", "type": [ "PubMed" ], "id": "19530166" } ], "title": "Localization of zip1 and zip4 mRNA in the adult rat brain.", "journal": "Journal of neuroscience research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" } ], "authors": "Belloni-Olivi L, Marshall C, Laal B, Andrews GK, Bressler J", "date": "2009" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/23013362", "type": [ "PubMed" ], "id": "23013362" } ], "title": "Chronic alcohol ingestion in rats decreases Kruppel-like factor 4 expression and intracellular zinc in the lung.", "journal": "Alcoholism, clinical and experimental research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" } ], "authors": "Curry-McCoy TV, Guidot DM, Joshi PC", "date": "2013" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/26702153", "type": [ "PubMed" ], "id": "26702153" } ], "title": "Properties of Zip4 accumulation during zinc deficiency and its usefulness to evaluate zinc status: a study of the effects of zinc deficiency during lactation.", "journal": "American journal of physiology. Regulatory, integrative and comparative physiology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" } ], "authors": "Hashimoto A, Nakagawa M, Tsujimura N, Miyazaki S, Kizu K, Goto T, Komatsu Y, Matsunaga A, Shirakawa H, Narita H, Kambe T, Komai M", "date": "2016" } ], "uniprot_ac": "A0JPN2", "site_annotation": [ { "end_pos": 194, "annotation": "n_glycosylation_sequon", "start_pos": 192 }, { "end_pos": 221, "annotation": "n_glycosylation_sequon", "start_pos": 219 }, { "end_pos": 269, "annotation": "n_glycosylation_sequon", "start_pos": 267 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2#A0A0H2UHY4-1", "isoform_ac": "A0A0H2UHY4-1", "locus": { "end_pos": 117675881, "strand": "+", "start_pos": 117679811, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000040422", "id": "ENSRNOT00000040422", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000047376", "id": "ENSRNOP00000047376", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0H2UHY4-1|S39A4_RAT Computationally mapped isoform of Zinc transporter ZIP4 OS=Rattus norvegicus OX=10116 GN=Slc39a4 PE=2 SV=1 CANONICAL=A0JPN2-1", "length": 657, "sequence": "MMLPKSLTQGLLLAMLVGTAAMVQPYHLLSLLTSGQGALDRTALDGLLNTLVARVHCTDGPCEKCLSVETALALGKPDKPQLAPESVLESRYITYLSAAAALYLNDPEKTCKDIRAGLLASHVDDYLAKLESPEAMTLGLSQLLQKIEAHDASQPTREETCVDVPQLLEEAEEAGVSRSPGLVLTALLDHVLNGSCFQGLPSPQYFVDFVFRQLSSKPRNITLPELEDLMHHLGVGGEDHSDHGDHVDHSHLDREANHQDSELHATHNSSSSVWDTLCLSAKDVMAVYGLSEEAGVSPQAWAQLTPALVQQQLSEACSSSPIIHVQDQLSQAERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDALLHLIPKVLGLHTHSGEVHSHEEESIGGQSTWRLLAVLGGFYIFFLFESFFNLLLPRDQDHEKDGPCSHGGHSHGISLQLSPSNLRQSKQPHESSRSDLVTEETPELLNPDTRRLRAELRMLPYLITLGDAVHNFADGLAVGAAFSSTWKTGLATSLAVFCHELPHELGDFAALLHAGLTVKRALLLNLASALTAFAGLYVALAVGVGEEGETWILAVATGLFLYVALCDMLPAMMNVRDQRPWLLFLLHNVGLLGGWTILLLLSLYEDSITF" } }, { "url": "https://www.uniprot.org/uniprot/A0JPN2#A0JPN2-1", "isoform_ac": "A0JPN2-1", "locus": {}, "sequence": { "header": "sp|A0JPN2-1|S39A4_RAT Isoform 1 of Zinc transporter ZIP4 OS=Rattus norvegicus OX=10116 GN=Slc39a4 PE=2 SV=1 CANONICAL=A0JPN2-1", "length": 656, "sequence": "MLPKSLTQGLLLAMLVGTAAMVQPYHLLSLLTSGQGALDRTALDGLLNTLVARVHCTDGPCEKCLSVETALALGKPDKPQLAPESVLESRYITYLSAAAALYLNDPEKTCKDIRAGLLASHVDDYLAKLESPEAMTLGLSQLLQKIEAHDASQPTREETCVDVPQLLEEAEEAGVSRSPGLVLTALLDHVLNGSCFQGLPSPQYFVDFVFRQLSSKPRNITLPELEDLMHHLGVGGEDHSDHGDHVDHSHLDREANHQDSELHATHNSSSSVWDTLCLSAKDVMAVYGLSEEAGVSPQAWAQLTPALVQQQLSEACSSSPIIHVQDQLSQAERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDALLHLIPKVLGLHTHSGEVHSHEEESIGGQSTWRLLAVLGGFYIFFLFESFFNLLLPRDQDHEKDGPCSHGGHSHGISLQLSPSNLRQSKQPHESSRSDLVTEETPELLNPDTRRLRAELRMLPYLITLGDAVHNFADGLAVGAAFSSTWKTGLATSLAVFCHELPHELGDFAALLHAGLTVKRALLLNLASALTAFAGLYVALAVGVGEEGETWILAVATGLFLYVALCDMLPAMMNVRDQRPWLLFLLHNVGLLGGWTILLLLSLYEDSITF" } }, { "url": "https://www.uniprot.org/uniprot/A0JPN2#M0RAL0-1", "isoform_ac": "M0RAL0-1", "locus": { "end_pos": 117676948, "strand": "+", "start_pos": 117679219, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000071522", "id": "ENSRNOT00000071522", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000066561", "id": "ENSRNOP00000066561", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|M0RAL0-1|S39A4_RAT Computationally mapped isoform of Zinc transporter ZIP4 OS=Rattus norvegicus OX=10116 GN=Slc39a4 PE=2 SV=2 CANONICAL=A0JPN2-1", "length": 343, "sequence": "VCPQCLSVETALALGKPDKPQLAPESVLESRYITYLSAAAALYLNDPEKTCKDIRAGLLASHVDDYLAKLESPEAMTLGLSQLLQKIEAHDASQPTREETCVDVPQLLEEAEEAGVSRSPGLVLTALLDHVLNGSCFQGLPSPQYFVDFVFRQLSSKPRNITLPELEDLMHHLGVGGEDHSDHGSSVWDTLCLSAKDVMAVYGLSEEAGVSPQAWAQLTPALVQQQLSEACSSSPIIHVQDQLSQAERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDLGGFYIFFLFESFFNLLLPRDQDHEKDGPCSHGGHSHGISLQLSPS" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:300051", "resource": "KEGG Pathway", "id": "rno:300051", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-442380", "resource": "Reactome", "id": "R-RNO-442380", "name": "Zinc influx into cells by the SLC39 gene family" } ], "function": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "annotation": "Chronic alcohol exposure decreases Kruppel-like factor (KLF)4 and ZIP4 expression and consequently decreases zinc transport into cells which, in turn, impairs their function.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" } ] }, { "url": "https://www.uniprot.org/uniprot/A0JPN2#function", "annotation": "Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2#function", "id": "A0JPN2", "database": "UniProtKB" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "annotation": "The localization of zip1 and zip4 was examined in the brains of adult rats", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "annotation": "The rapid upregulation of Zip4 expression in the small intestine during zinc deficient conditions corroborates the important role of Zip4 in the systemic control of zinc homeostasis.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q6P5W5-1", "protein_name": "Zinc transporter ZIP4", "sequence": { "length": 647, "sequence": "MASLVSLELGLLLAVLVVTATASPPAGLLSLLTSGQGALDQEALGGLLNTLADRVHCANGPCGKCLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKMACVDIPQLLEEAVGAGAPGSAGGVLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGAVTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/15638", "id": "15638", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "Q78IQ7-1", "protein_name": "Zinc transporter ZIP4", "sequence": { "length": 660, "sequence": "MLPKSVTQGLVLALLVGTVAVARPRNLLSLLALGQGALDRLELDGLLNTLVARVHCTDGPCEKCLSVENVLALGKPDKPQPAPESVLESRHIIYLSAAAALYLNNPEKTCKDIQAGLLASHVDDYLATLESPEAMTLGLSQLLQKIEAHAASQPTGEKTCVDLPQLLEEAEAAGVSKSAGLVLTALLDHVINGSCFQGLPSPQYFVDFVFRLHSSDPPNITLHELENLMHHLGVGGEDHSDHDDHGDHADHSHPDRKASHQDSELHTPHNSNSSVWDTLCLSAKDIMAVYGLSEEAGVSPQAWAQLTPALVQQQLSGACSPYPTIRIQDQLSQTERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDALLHLIPKVLGLHTHGGEGHTHEEEVGVGGQATWRLLAVLGGFYIFFLFESFFNLLLPRDQDSEKDGPCSHGGHSHGISLQLAPSNLRQSKQTHESSRSDLVAEETPELLNPETRRLRAELRLLPYLITLGDAVHNFADGLAVGAAFSSSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVKRALLLNLASALTAFAGLYVALAVGVGEEGEAWILAVATGLFLYVALCDMLPAMMNVRDQRPWLLFLLHNVGLLGGWTVLLLLSLYEDNITF" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/15638", "id": "15638", "database": "MGI" } ], "common_name": "Mouse", "organism": "Mus musculus", "tax_id": 10090 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "ac": "NP_001071137.1", "name": "zinc transporter ZIP4 precursor", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "id": "A0JPN2", "database": "UniProtKB" } ], "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385" } ], "total": 1, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005887", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "id": "A0JPN2", "database": "UniProtKB" } ], "name": "integral component of plasma membrane", "id": "GO:0005887" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "id": "A0JPN2", "database": "UniProtKB" } ], "name": "plasma membrane", "id": "GO:0005886" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "id": "A0JPN2", "database": "UniProtKB" } ], "name": "cytoplasmic vesicle", "id": "GO:0031410" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "id": "A0JPN2", "database": "UniProtKB" } ], "name": "recycling endosome membrane", "id": "GO:0055038" } ], "total": 4, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "id": "A0JPN2", "database": "UniProtKB" } ], "name": "signal transduction", "id": "GO:0007165" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006882", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "id": "A0JPN2", "database": "UniProtKB" } ], "name": "cellular zinc ion homeostasis", "id": "GO:0006882" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071578", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "id": "A0JPN2", "database": "UniProtKB" } ], "name": "zinc ion import across plasma membrane", "id": "GO:0071578" } ], "total": 3, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A0JPN2", "type": "synonym", "resource": "RefSeq", "name": "Slc39a4" }, { "url": "https://www.uniprot.org/uniprot/A0JPN2", "type": "recommended", "resource": "UniProtKB", "name": "Slc39a4" }, { "url": "https://www.uniprot.org/uniprot/A0JPN2", "type": "synonym", "resource": "UniProtKB", "name": "Zip4" } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/gene/300051", "id": "300051", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR003689", "id": "IPR003689", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR041137", "id": "IPR041137", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:300051", "id": "rno:300051", "database": "KEGG Pathway" }, { "url": "https://omabrowser.org/oma/group/KDGPCSH/", "id": "KDGPCSH", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=657777at2759", "id": "657777at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF02535", "id": "PF02535", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF18292", "id": "PF18292", "database": "Pfam" }, { "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A0JPN2", "id": "PR_A0JPN2", "database": "PRO" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-442380", "id": "R-RNO-442380", "database": "Reactome" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071137.1", "id": "NP_001071137.1", "database": "RefSeq" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306701", "id": "1306701", "database": "RGD" } ], "expression_disease": [], "glycosylation": [ { "residue": "Asn", "site_category": "predicted", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2#ptm_processing", "id": "A0JPN2", "database": "UniProtKB" } ], "subtype": "", "relation": "attached", "position": 192, "glytoucan_ac": "", "type": "N-linked" }, { "residue": "Asn", "site_category": "predicted", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2#ptm_processing", "id": "A0JPN2", "database": "UniProtKB" } ], "subtype": "", "relation": "attached", "position": 219, "glytoucan_ac": "", "type": "N-linked" }, { "residue": "Asn", "site_category": "predicted", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2#ptm_processing", "id": "A0JPN2", "database": "UniProtKB" } ], "subtype": "", "relation": "attached", "position": 267, "glytoucan_ac": "", "type": "N-linked" } ], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 71121.0, "chemical_mass": 71121.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "name": "Slc39a4", "locus": { "end_pos": 117675720, "strand": "-", "start_pos": 117680004, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000014314", "id": "ENSRNOG00000014314", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A0JPN2", "type": "synonym", "resource": "UniProtKB", "name": "Solute carrier family 39 member 4" }, { "url": "https://www.uniprot.org/uniprot/A0JPN2", "type": "synonym", "resource": "UniProtKB", "name": "ZIP-4" }, { "url": "https://www.uniprot.org/uniprot/A0JPN2", "type": "recommended", "resource": "UniProtKB", "name": "Zinc transporter ZIP4" }, { "url": "https://www.uniprot.org/uniprot/A0JPN2", "type": "synonym", "resource": "UniProtKB", "name": "Zrt- and Irt-like protein 4" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0JPN2", "type": "synonym", "resource": "RefSeq", "name": "zinc transporter ZIP4 precursor" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0JPN2", "type": "synonym", "resource": "RefSeq", "name": "zinc transporter ZIP4; ZIP-4; zrt- and Irt-like protein 4; solute carrier family 39 (zinc transporter), member 4" } ] }