{ "uniprot_canonical_ac": "A0JP26-1", "ptm_annotation": [], "sequence": { "header": "sp|A0JP26-1|POTB3_HUMAN Isoform 1 of POTE ankyrin domain family member B3 OS=Homo sapiens OX=9606 GN=POTEB3 PE=2 SV=2 CANONICAL=A0JP26-1", "length": 581, "sequence": "MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKTLRSKMGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRENKILEEIESVKEKLLKAIQLNEEALTKTSI" }, "uniprot_id": "POTB3_HUMAN", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Human", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JP26", "id": "A0JP26", "database": "UniProtKB" } ], "name": "Homo sapiens", "taxid": 9606 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/15276201", "type": [ "PubMed" ], "id": "15276201" } ], "title": "Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.", "journal": "Gene", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0JP26", "id": "A0JP26", "database": "UniProtKB" } ], "authors": "Maeda H., Bera T.K., Lee B., Pastan I., Huynh N., Sathyanarayana B.K.", "date": "2004" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/19718026", "type": [ "PubMed" ], "id": "19718026" } ], "title": "Personalized copy number and segmental duplication maps using next-generation sequencing.", "journal": "Nature genetics", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997238.2", "id": "NP_997238.2", "database": "RefSeq" } ], "authors": "Alkan C, Kidd JM, Marques-Bonet T, Aksay G, Antonacci F, Hormozdiari F, Kitzman JO, Baker C, Malig M, Mutlu O, Sahinalp SC, Gibbs RA, Eichler EE", "date": "2009" } ], "uniprot_ac": "A0JP26", "site_annotation": [ { "end_pos": 434, "annotation": "n_glycosylation_sequon", "start_pos": 432 }, { "end_pos": 476, "annotation": "n_glycosylation_sequon", "start_pos": 474 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0JP26#A0A0C4DH93-1", "isoform_ac": "A0A0C4DH93-1", "locus": { "end_pos": 21420693, "strand": "+", "start_pos": 21440011, "chromosome": "15", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000624267", "id": "ENST00000624267", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000485523", "id": "ENSP00000485523", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0C4DH93-1|POTB3_HUMAN Computationally mapped isoform of POTE ankyrin domain family member B3 OS=Homo sapiens OX=9606 GN=POTEB3 PE=2 SV=1 CANONICAL=A0JP26-1", "length": 384, "sequence": "MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKTLRSKMGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPENVSRTRNK" } }, { "url": "https://www.uniprot.org/uniprot/A0JP26#A0A0G2JMU2-1", "isoform_ac": "A0A0G2JMU2-1", "locus": { "end_pos": 21409023, "strand": "+", "start_pos": 21440041, "chromosome": "15", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000615774", "id": "ENST00000615774", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000479963", "id": "ENSP00000479963", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2JMU2-1|POTB3_HUMAN Computationally mapped isoform of POTE ankyrin domain family member B3 OS=Homo sapiens OX=9606 GN=POTEB3 PE=2 SV=1 CANONICAL=A0JP26-1", "length": 581, "sequence": "MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKTLRSKMGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRENKILEEIESVKEKLLKAIQLNEEALTKTSI" } }, { "url": "https://www.uniprot.org/uniprot/A0JP26#A0A0G2JQ08-1", "isoform_ac": "A0A0G2JQ08-1", "locus": { "end_pos": 21426283, "strand": "+", "start_pos": 21440041, "chromosome": "15", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000617395", "id": "ENST00000617395", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000484709", "id": "ENSP00000484709", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2JQ08-1|POTB3_HUMAN Computationally mapped isoform of POTE ankyrin domain family member B3 OS=Homo sapiens OX=9606 GN=POTEB3 PE=2 SV=1 CANONICAL=A0JP26-1", "length": 381, "sequence": "MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKTLRSKMGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPGKEAEE" } }, { "url": "https://www.uniprot.org/uniprot/A0JP26#A0A0G2JQB7-1", "isoform_ac": "A0A0G2JQB7-1", "locus": { "end_pos": 21420742, "strand": "+", "start_pos": 21440041, "chromosome": "15", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000630023", "id": "ENST00000630023", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000485729", "id": "ENSP00000485729", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2JQB7-1|POTB3_HUMAN Computationally mapped isoform of POTE ankyrin domain family member B3 OS=Homo sapiens OX=9606 GN=POTEB3 PE=2 SV=1 CANONICAL=A0JP26-1", "length": 384, "sequence": "MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKTLRSKMGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPENVSRTRNK" } }, { "url": "https://www.uniprot.org/uniprot/A0JP26#A0A0G2JRD4-1", "isoform_ac": "A0A0G2JRD4-1", "locus": { "end_pos": 21420740, "strand": "+", "start_pos": 21439823, "chromosome": "15", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000631051", "id": "ENST00000631051", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000486649", "id": "ENSP00000486649", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2JRD4-1|POTB3_HUMAN Computationally mapped isoform of POTE ankyrin domain family member B3 OS=Homo sapiens OX=9606 GN=POTEB3 PE=2 SV=1 CANONICAL=A0JP26-1", "length": 266, "sequence": "XGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRYGRICELLSDYKEKQMLKISSENSNPENVSRTRNK" } }, { "url": "https://www.uniprot.org/uniprot/A0JP26#A0JP26-1", "isoform_ac": "A0JP26-1", "locus": {}, "sequence": { "header": "sp|A0JP26-1|POTB3_HUMAN Isoform 1 of POTE ankyrin domain family member B3 OS=Homo sapiens OX=9606 GN=POTEB3 PE=2 SV=2 CANONICAL=A0JP26-1", "length": 581, "sequence": "MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKTLRSKMGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRENKILEEIESVKEKLLKAIQLNEEALTKTSI" } }, { "url": "https://www.uniprot.org/uniprot/A0JP26#A0JP26-2", "isoform_ac": "A0JP26-2", "locus": {}, "sequence": { "header": "sp|A0JP26-2|POTB3_HUMAN Isoform 2 of POTE ankyrin domain family member B3 OS=Homo sapiens OX=9606 GN=POTEB3 PE=2 SV=2 CANONICAL=A0JP26-1", "length": 381, "sequence": "MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKTLRSKMGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPGKEAEE" } }, { "url": "https://www.uniprot.org/uniprot/A0JP26#A0JP26-3", "isoform_ac": "A0JP26-3", "locus": {}, "sequence": { "header": "sp|A0JP26-3|POTB3_HUMAN Isoform 3 of POTE ankyrin domain family member B3 OS=Homo sapiens OX=9606 GN=POTEB3 PE=2 SV=2 CANONICAL=A0JP26-1", "length": 544, "sequence": "MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGKSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRENKILEEIESVKEKLLKAIQLNEEALTKTSI" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:102724631", "resource": "KEGG Pathway", "id": "hsa:102724631", "name": "" } ], "function": [], "orthologs": [], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997238.2", "ac": "NP_997238.2", "name": "POTE ankyrin domain family member B3", "summary": "" }, "go_annotation": {}, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A0JP26", "type": "synonym", "resource": "RefSeq", "name": "POTE-15; POTEB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0JP26", "type": "synonym", "resource": "RefSeq", "name": "POTEB3" }, { "url": "https://www.uniprot.org/uniprot/A0JP26", "type": "recommended", "resource": "UniProtKB", "name": "POTEB3" } ], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000278522", "id": "ENSG00000278522", "database": "Bgee" }, { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0JP26", "id": "A0JP26", "database": "BioMuta" }, { "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=POTEB3", "id": "POTEB3", "database": "GeneCards" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/102724631", "id": "102724631", "database": "GeneID" }, { "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=51240", "id": "51240", "database": "HGNC" }, { "url": "https://www.ebi.ac.uk/intact/interactors/id:A0JP26*", "id": "A0JP26", "database": "IntAct" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "id": "IPR002110", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR020683", "id": "IPR020683", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "id": "IPR036770", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR039497", "id": "IPR039497", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:102724631", "id": "hsa:102724631", "database": "KEGG Pathway" }, { "url": "https://www.nextprot.org/entry/NX_A0JP26", "id": "NX_A0JP26", "database": "neXtProt" }, { "url": "https://omabrowser.org/oma/group/DYHRICQ/", "id": "DYHRICQ", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=397907at2759", "id": "397907at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF12796", "id": "PF12796", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF14915", "id": "PF14915", "database": "Pfam" }, { "url": "https://pharos.nih.gov/targets/A0JP26", "id": "A0JP26", "database": "PHAROS" }, { "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A0JP26", "id": "PR_A0JP26", "database": "PRO" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997238.2", "id": "NP_997238.2", "database": "RefSeq" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 65710.0, "chemical_mass": 65710.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0JP26", "name": "POTEB3", "locus": { "end_pos": 21408243, "strand": "-", "start_pos": 21440451, "chromosome": "15", "evidence": [ { "url": "https://www.ensembl.org/id/ENSG00000278522", "id": "ENSG00000278522", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A0JP26", "type": "synonym", "resource": "RefSeq", "name": "ANKRD26-like family B member 1; prostate, ovary, testis-expressed protein on chromosome 15; POTE ankyrin domain family member B; POTE ankyrin domain family, member B-like" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0JP26", "type": "synonym", "resource": "RefSeq", "name": "POTE ankyrin domain family member B3" }, { "url": "https://www.uniprot.org/uniprot/A0JP26", "type": "recommended", "resource": "UniProtKB", "name": "POTE ankyrin domain family member B3" } ] }