{ "bcoid": "GLY_000125", "title": "Human UniProtKB Xref Reactome", "description": "The Human UniProtKB Xref Reactome contains human [taxid:9606] UniProtKB canonical accessions cross-referenced ...", "filename": "human_protein_xref_reactome.csv", "filetype": "csv", "categories": { "species": "Homo sapiens", "molecule": "Protein", "tags": "Reactome cross-references", "file_type": "csv", "status": "Reviewed", "scope": "internal" }, "minitable": { "content": [ [ "Q8TBF5-1...", "protein_xref..." ], [ "Q8TBF4-1...", "protein_xref..." ] ], "headers": [ "uniprotkb_ca...", "xref_key..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "uniprotkb_canonical_ac" }, { "type": "string", "label": "xref_key" }, { "type": "string", "label": "xref_id" }, { "type": "string", "label": "xref_label" } ], [ "Q8TBF5-1", "protein_xref_reactome", "R-HSA-162710", "Synthesis of glycosylphosphatidylinositol (GPI)" ], [ "Q8TBF4-1", "protein_xref_reactome", "R-HSA-72165", "mRNA Splicing - Minor Pathway" ], [ "Q8TBF4-1", "protein_xref_reactome", "R-HSA-72165", "mRNA Splicing - Minor Pathway" ], [ "Q8TBF4-1", "protein_xref_reactome", "R-HSA-72165", "mRNA Splicing - Minor Pathway" ], [ "Q8TBF4-1", "protein_xref_reactome", "R-HSA-72165", "mRNA Splicing - Minor Pathway" ], [ "Q8TBF4-1", "protein_xref_reactome", "R-HSA-72165", "mRNA Splicing - Minor Pathway" ], [ "Q9NRJ4-1", "protein_xref_reactome", "R-HSA-8951664", "Neddylation" ], [ "Q9NRJ4-1", "protein_xref_reactome", "R-HSA-8951664", "Neddylation" ], [ "Q9NRJ4-1", "protein_xref_reactome", "R-HSA-8951664", "Neddylation" ], [ "Q9NRJ4-1", "protein_xref_reactome", "R-HSA-8951664", "Neddylation" ], [ "Q9NRJ4-1", "protein_xref_reactome", "R-HSA-8951664", "Neddylation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73779", "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73779", "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73779", "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73779", "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167161", "HIV Transcription Initiation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167172", "Transcription of the HIV genome" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167161", "HIV Transcription Initiation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167161", "HIV Transcription Initiation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167161", "HIV Transcription Initiation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167161", "HIV Transcription Initiation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167162", "RNA Polymerase II HIV Promoter Escape" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167162", "RNA Polymerase II HIV Promoter Escape" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167162", "RNA Polymerase II HIV Promoter Escape" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167162", "RNA Polymerase II HIV Promoter Escape" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167172", "Transcription of the HIV genome" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-6804756", "Regulation of TP53 Activity through Phosphorylation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-674695", "RNA Polymerase II Pre-transcription Events" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73779", "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-75953", "RNA Polymerase II Transcription Initiation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-674695", "RNA Polymerase II Pre-transcription Events" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-674695", "RNA Polymerase II Pre-transcription Events" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73776", "RNA Polymerase II Promoter Escape" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73776", "RNA Polymerase II Promoter Escape" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73776", "RNA Polymerase II Promoter Escape" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73779", "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-75953", "RNA Polymerase II Transcription Initiation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-75953", "RNA Polymerase II Transcription Initiation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-75953", "RNA Polymerase II Transcription Initiation" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-76042", "RNA Polymerase II Transcription Initiation And Promoter Clearance" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167162", "RNA Polymerase II HIV Promoter Escape" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73776", "RNA Polymerase II Promoter Escape" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-167162", "RNA Polymerase II HIV Promoter Escape" ], [ "Q5H9L4-1", "protein_xref_reactome", "R-HSA-73776", "RNA Polymerase II Promoter Escape" ], [ "P20930-1", "protein_xref_reactome", "R-HSA-6809371", "Formation of the cornified envelope" ], [ "P20930-1", "protein_xref_reactome", "R-HSA-6809371", "Formation of the cornified envelope" ], [ "P20930-1", "protein_xref_reactome", "R-HSA-6809371", "Formation of the cornified envelope" ], [ "P20930-1", "protein_xref_reactome", "R-HSA-6809371", "Formation of the cornified envelope" ], [ "P20930-1", "protein_xref_reactome", "R-HSA-6809371", "Formation of the cornified envelope" ], [ "P20930-1", "protein_xref_reactome", "R-HSA-6809371", "Formation of the cornified envelope" ], [ "P20930-1", "protein_xref_reactome", "R-HSA-6809371", "Formation of the cornified envelope" ], [ "P20930-1", "protein_xref_reactome", "R-HSA-6809371", "Formation of the cornified envelope" ], [ "P20930-1", "protein_xref_reactome", "R-HSA-6809371", "Formation of the cornified envelope" ], [ "P20933-1", "protein_xref_reactome", "R-HSA-6798695", "Neutrophil degranulation" ], [ "P20936-1", "protein_xref_reactome", "R-HSA-186763", "Downstream signal transduction" ], [ "P20936-1", "protein_xref_reactome", "R-HSA-3928662", "EPHB-mediated forward signaling" ], [ "P20936-1", "protein_xref_reactome", "R-HSA-3928662", "EPHB-mediated forward signaling" ], [ "P20936-1", "protein_xref_reactome", "R-HSA-3928662", "EPHB-mediated forward signaling" ], [ "P20936-1", "protein_xref_reactome", "R-HSA-8849471", "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" ], [ "P20936-1", "protein_xref_reactome", "R-HSA-8849471", "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" ], [ "P20936-1", "protein_xref_reactome", "R-HSA-8849471", "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" ], [ "P20936-1", "protein_xref_reactome", "R-HSA-5218921", "VEGFR2 mediated cell proliferation" ], [ "P20936-1", "protein_xref_reactome", "R-HSA-5658442", "Regulation of RAS by GAPs" ], [ "P20936-1", "protein_xref_reactome", "R-HSA-5658442", "Regulation of RAS by GAPs" ], [ "Q9UM21-1", "protein_xref_reactome", "R-HSA-381426", "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" ], [ "Q9UM21-1", "protein_xref_reactome", "R-HSA-8957275", "Post-translational protein phosphorylation" ], [ "Q9UM21-1", "protein_xref_reactome", "R-HSA-975577", "N-Glycan antennae elongation" ], [ "P83859-1", "protein_xref_reactome", "R-HSA-416476", "G alpha (q) signalling events" ], [ "P83859-1", "protein_xref_reactome", "R-HSA-389397", "Orexin and neuropeptides FF and QRFP bind to their respective receptors" ], [ "P83859-1", "protein_xref_reactome", "R-HSA-416476", "G alpha (q) signalling events" ], [ "P83859-1", "protein_xref_reactome", "R-HSA-416476", "G alpha (q) signalling events" ], [ "Q70EL4-1", "protein_xref_reactome", "R-HSA-5656169", "Termination of translesion DNA synthesis" ], [ "Q70EL4-1", "protein_xref_reactome", "R-HSA-5656169", "Termination of translesion DNA synthesis" ], [ "Q8TBF2-1", "protein_xref_reactome", "R-HSA-2162123", "Synthesis of Prostaglandins (PG) and Thromboxanes (TX)" ], [ "Q15573-1", "protein_xref_reactome", "R-HSA-427359", "SIRT1 negatively regulates rRNA expression" ], [ "Q15573-1", "protein_xref_reactome", "R-HSA-427413", "NoRC negatively regulates rRNA expression" ], [ "Q15573-1", "protein_xref_reactome", "R-HSA-5250924", "B-WICH complex positively regulates rRNA expression" ], [ "Q15573-1", "protein_xref_reactome", "R-HSA-5250924", "B-WICH complex positively regulates rRNA expression" ], [ "Q15573-1", "protein_xref_reactome", "R-HSA-5250924", "B-WICH complex positively regulates rRNA expression" ], [ "Q15573-1", "protein_xref_reactome", "R-HSA-73762", "RNA Polymerase I Transcription Initiation" ], [ "Q15573-1", "protein_xref_reactome", "R-HSA-73762", "RNA Polymerase I Transcription Initiation" ], [ "Q15573-1", "protein_xref_reactome", "R-HSA-73762", "RNA Polymerase I Transcription Initiation" ], [ "Q15573-1", "protein_xref_reactome", "R-HSA-73762", "RNA Polymerase I Transcription Initiation" ], [ "Q15573-1", "protein_xref_reactome", "R-HSA-73772", "RNA Polymerase I Promoter Escape" ] ] }, "readme": "Name\n - Human UniProtKB Xref Reactome\n\nVersion\n - 1.7.10\n\nCreated on\n - 2019-03-15T16:14:06.456984\n\nModified on\n - 2020-04-10T11:39:49.739285\n\nCreated by\n - Jeet Vora [jeetvora@gwu.edu], Rahi Navelkar [rsn13@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Xavier Holmes [xavierh@email.gwu.edu]\n\nAuthors\n - Maria Martin [martin@ebi.ac.uk], Preethi Vasudev [pvasudev@ebi.ac.uk]\n\nChecksum\n - \n\nUsability Domain\n - The Human UniProtKB Xref Reactome contains human [taxid:9606] UniProtKB canonical accessions cross-referenced to Reactome database accessions/identifiers. The dataset is derived from 2019-09 UniProtKB release. If you use this dataset please provide proper attribution to EMBL-EBI-UniProtKB and GlyGen\n - REACTOME is an open-source, open access, manually curated and peer-reviewed pathway database. \n\nDescription Domain\n Keywords\n - pathways\n - reactions\n - REACTOME\n - cross-reference\n\n Pipeline Steps\n - Step-1: The script loads the UniProtKB canonical accessions that are cross-referenced to REACTOME database accessions/identifiers from the triplestore containing triples from nt file and extracts the data as a csv dataset\n\nExecution Domain\n Scripts - https://github.com/GW-HIVE/glygen-backend-integration/blob/master/pipeline/integrator/make-protein-dataset.py\n\n\n Software Prerequisites\n Name: Python\n Version: 2.7.5\n URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n Input Subdomain\n Name: uniprot-proteome-homo-sapiens.nt\n URI: https://data.glygen.org/ln2wwwdata/source/uniprot-proteome-homo-sapiens.nt\n Output Subdomain\n Name: human_protein_xref_reactome.csv\n URI: http://data.glygen.org/ln2wwwdata/reviewed/human_protein_xref_reactome.csv\n Name: human_protein_xref_reactome.stat.csv\n URI: http://data.glygen.org/ln2wwwdata/reviewed/human_protein_xref_reactome.stat.csv\n\nFields\n Name: \"uniprotkb_canonical_ac\"\n Description: \"\"\n Unique Values: \"10653\"\n Name: \"xref_label\"\n Description: \"Label/Name associated with x-ref\"\n Unique Values: \"1868\"\n Name: \"xref_id\"\n Description: \"ID of the X-ref\"\n Unique Values: \"1877\"\n Name: \"xref_key\"\n Description: \"Source key associated to the xref_id\"\n Unique Values: \"1\"", "downloadurl": "/ln2data/releases/data/v-1.7.10/reviewed/human_protein_xref_reactome.csv" }