{
    "uniprot_canonical_ac": "A4D0T2-1", 
    "sequence": {
        "length": 115, 
        "sequence": "MMAVMTPSDGLSQLSVPHLTHQRLWSLSCLAMLFQAVLILSAPQMSCLLKCFYALDPLHPVMSEEFSAQYRHMMDQRYRTRIHEGYISQVKGAYLRIVHKKPISYAKSFPKEMGN"
    }, 
    "uniprot_id": "CG066_HUMAN", 
    "enzyme_annotation": [], 
    "alternativenames": [], 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A4D0T2", 
                    "id": "A4D0T2", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Uncharacterized protein C7orf66"
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [
        {
            "start_pos": 79, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A4D0T2", 
                    "id": "A4D0T2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "0.0139", 
            "annotation": "Somatic mutation in Breast cancer (DOID:1612) with frequency of 1/72 (0.0139)", 
            "sequence_org": "R", 
            "disease": {
                "doid": "1612", 
                "url": "http://disease-ontology.org/term/DOID:1612", 
                "icd10": "", 
                "name": "Breast cancer"
            }, 
            "sequence_mut": "T", 
            "subjects_tested": "72", 
            "end_pos": 79, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 76, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A4D0T2", 
                    "id": "A4D0T2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "0.0263", 
            "annotation": "Somatic mutation in Lung cancer (DOID:1324) with frequency of 1/38 (0.0263)", 
            "sequence_org": "Q", 
            "disease": {
                "doid": "1324", 
                "url": "http://disease-ontology.org/term/DOID:1324", 
                "icd10": "", 
                "name": "Lung cancer"
            }, 
            "sequence_mut": "R", 
            "subjects_tested": "38", 
            "end_pos": 76, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 38, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A4D0T2", 
                    "id": "A4D0T2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "0.0106", 
            "annotation": "Somatic mutation in Colorectal cancer (DOID:9256) with frequency of 1/94 (0.0106)", 
            "sequence_org": "L", 
            "disease": {
                "doid": "9256", 
                "url": "http://disease-ontology.org/term/DOID:9256", 
                "icd10": "", 
                "name": "Colorectal cancer"
            }, 
            "sequence_mut": "I", 
            "subjects_tested": "94", 
            "end_pos": 38, 
            "type": "Point mutation"
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A4D0T2#A4D0T2-1", 
            "isoform_ac": "A4D0T2-1", 
            "locus": {
                "end_pos": 0, 
                "start_pos": 0, 
                "chromosome": "", 
                "evidence": []
            }, 
            "sequence": {
                "length": 115, 
                "sequence": "MMAVMTPSDGLSQLSVPHLTHQRLWSLSCLAMLFQAVLILSAPQMSCLLKCFYALDPLHPVMSEEFSAQYRHMMDQRYRTRIHEGYISQVKGAYLRIVHKKPISYAKSFPKEMGN"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:154907", 
            "resource": "KEGG Pathway", 
            "id": "hsa:154907", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019778.1", 
        "ac": "NP_001019778.1", 
        "name": "uncharacterized protein C7orf66", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4D0T2", 
                                "id": "A4D0T2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:154907", 
            "id": "hsa:154907", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=33712", 
            "id": "33712", 
            "database": "HGNC"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=C7orf66", 
            "id": "C7orf66", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/154907", 
            "id": "154907", 
            "database": "GeneID"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A4D0T2", 
            "id": "PR_A4D0T2", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A4D0T2", 
            "id": "NX_A4D0T2", 
            "database": "neXtProt"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A4D0T2", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 13234.0, 
        "chemical_mass": 13234.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=33712", 
            "name": "C7orf66", 
            "locus": {
                "end_pos": 108883975, 
                "start_pos": 108884587, 
                "chromosome": "7", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000205174", 
                        "id": "ENSG00000205174", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}