{ "uniprot_canonical_ac": "A2VEC9-1", "sequence": { "length": 5150, "sequence": "MLLPALLFGMAWALADGRWCEWTETIRVEEEVAPRQEDLVPCASLDHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMWQCQLQAGSANASAGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDSPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVCDGQPDCGRPGQVGPSPEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGPCRVCQCLHNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTVQPMATPAAAPAPSPQIRFPLATYILPPSGDPCYSPLGLAGLAEGSLHASSQQLEHPTQAALLGAPTQGPSPQGWHAGGDAYAKWHTRPHYLQLDLLQPRNLTGILVPETGSSNAYASSFSLQFSSNGLHWHDYRDLLPGILPLPKLFPRNWDDLDPAVWTFGRMVQARFVRVWPHDVHHSDVPLQVELLGCEPGSPPAPLCPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGCVLLPEGTGRFHSTAKTLALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLGCVEQAQVCDGREDCLDGSDERHCARNLLMWLPSLPALWAASTVPFMMPTMALPGLPASRALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGCVDCVLAPWSVWSSCSRSCGLGLTFQRQELLRPPLPGGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLEYCPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPESCEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDCCSYRLDPESPVRILNLRCLGGHTEPVVLPVIHSCQCSSCQGGDFSKR" }, "uniprot_id": "SSPO_HUMAN", "enzyme_annotation": [], "alternativenames": [], "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9", "id": "A2VEC9", "database": "UniProtKB" } ], "name": "Homo sapiens", "taxid": 9606 } ], "recommendedname": { "full": "SCO-spondin" }, "publication": [ { "title": "Structure and function insights garnered from in silico modeling of the thrombospondin type-1 domain-containing 7A antigen.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/30520531", "journal": "Proteins", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9/publications", "id": "A2VEC9", "database": "UniProtKB" } ], "authors": "Ma H., Aramandla M.P., Beck L.H. Jr., Palopoli M.M., Patel R.M., Stoddard S.D., Stoddard S.V., Welsh C.L.", "date": "2019", "pmid": "30520531" }, { "title": "Joubert Syndrome in French Canadians and Identification of Mutations in CEP104.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/26477546", "journal": "Am. J. Hum. Genet.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9/publications", "id": "A2VEC9", "database": "UniProtKB" } ], "authors": "Elpeleg O., Lemyre E., Shalev S., Dionne-Laporte A., Hamdan F.F., Massicotte C., Michaud J.L., Nassif C., Patry L., Rouleau G.A., Srour M., Majewski J., Mandel H., Davis E., Labuda D., Laframboise R., Maranda B., Ospina L.H., Schwartzentruber J., Boucher R.M., Boycott K., Brais B., Decarie J.C., Fallet-Bianco C., Goldsher D., Katsanis N., Kukolich M.K., Laberge A.M., Maftei C., Martin B., McKnight D., Rypens F., Soucy J.F.", "date": "2015", "pmid": "26477546" }, { "title": "The complex multidomain organization of SCO-spondin protein is highly conserved in mammals.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/17126404", "journal": "Brain Res. Brain Res. Rev.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9/publications", "id": "A2VEC9", "database": "UniProtKB" } ], "authors": "Meiniel A., Meiniel O.", "date": "2007", "pmid": "17126404" } ], "glycosylation": [ { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 3948, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 2937, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 2031, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 912, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 987, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 3400, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 4958, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": 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"https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 820, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 2695, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 4866, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 3600, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": 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"https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 4906, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 3916, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 1664, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 515, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 945, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 3793, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 3063, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 1994, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 4751, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 3311, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 1353, "glytoucan_ac": "GlcNAc...", "type": "N-linked" }, { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#ptm_processing", "id": "A2VEC9-1", "database": "UniProtKB" } ], "relation": "attached", "position": 3164, "glytoucan_ac": "GlcNAc...", "type": "N-linked" } ], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#A2VEC9-1", "isoform_ac": "A2VEC9-1", "locus": { "end_pos": 149776042, "start_pos": 149833826, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000378016", "id": "ENST00000378016", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000485256", "id": "ENSP00000485256", "database": "Ensembl Peptide" } ] }, "sequence": { "length": 5150, "sequence": "MLLPALLFGMAWALADGRWCEWTETIRVEEEVAPRQEDLVPCASLDHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMWQCQLQAGSANASAGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDSPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVCDGQPDCGRPGQVGPSPEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGPCRVCQCLHNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTVQPMATPAAAPAPSPQIRFPLATYILPPSGDPCYSPLGLAGLAEGSLHASSQQLEHPTQAALLGAPTQGPSPQGWHAGGDAYAKWHTRPHYLQLDLLQPRNLTGILVPETGSSNAYASSFSLQFSSNGLHWHDYRDLLPGILPLPKLFPRNWDDLDPAVWTFGRMVQARFVRVWPHDVHHSDVPLQVELLGCEPGSPPAPLCPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGCVLLPEGTGRFHSTAKTLALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLGCVEQAQVCDGREDCLDGSDERHCARNLLMWLPSLPALWAASTVPFMMPTMALPGLPASRALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGCVDCVLAPWSVWSSCSRSCGLGLTFQRQELLRPPLPGGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLEYCPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPESCEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDCCSYRLDPESPVRILNLRCLGGHTEPVVLPVIHSCQCSSCQGGDFSKR" } }, { "url": "https://www.uniprot.org/uniprot/A2VEC9#A2VEC9-2", "isoform_ac": "A2VEC9-2", "locus": { "end_pos": 0, "start_pos": 0, "chromosome": "", "evidence": [] }, "sequence": { "length": 1317, "sequence": "MLPPGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDACVEAPAPPAMRGPPGQAGGPTSSRAPSPPSPPEAQGEGRKGQERSRTHLTVPAGSTQLPLCPGLFPCGVAPGLCLTPEQLCDGIPDCPQGEDELDCGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVRVGVGGGGGSAMLPPSTRALTPLPPQVCDGQPDCGRPGQVGPSPEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGPCRVCQCLHNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTVQPMATPAAAPAPSPQIRFPLATYILPPSGDPCYSPLGLAGLAEGSLHASSQQLEHPTQAALLGAPTQGPSPQGWHAGGDAYAKWHTRPHYLQLDLLQPRNLTGILVPETGSSNAYASSFSLQFSSNGLHWHDYRDLLPGILPLPKVSPAQGRWGQQPTMPFCGFHSLCPQGPSSVPEGHGLHSMLVEYLVSSRDCALWSRGLGATVTWMLETIQVAQTQGRYVKPARERGWGDTKFTEGLREPRPTHVFVESSLGTALPSGGLHPSRRQTARSGRNQSVLCSKR" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5173214", "resource": "Reactome", "id": "R-HSA-5173214", "name": "O-glycosylation of TSR domain-containing proteins" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5083635", "resource": "Reactome", "id": "R-HSA-5083635", "name": "Defective B3GALTL causes Peters-plus syndrome (PpS)" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#function", "annotation": "Involved in the modulation of neuronal aggregation. May be involved in developmental events during the formation of the central nervous system (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9#function", "id": "A2VEC9", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q700K0-1", "protein_name": "SCO-spondin", "sequence": { "length": 5141, "sequence": "MLLPALLFGMLWAPANGHWCEQIETVHVEEEVTPRREDLVPCTSLYHYSRLGWKLDLSWGGHVGLTRPPALGLCAIYKPPETRPATWNRTVRACCPGWGGIHCTEALAEASPKGHCFVTWHCQPLAGSANSSAGSLEECCAQPWGHSWWNSSSQMCLSCSGQHRPGNASSEGLLQPLAGAVGQLWSQRQRPSATCATWSGFHYQTFDGQHYHFLGQCTYLLAGAMDSTWAVHLRPSVHCPQPRQCWLVQVIMGPEEVLIQDGEVSVKGQPVPVGESQLLHGMSLQWQGDWLVLSGGLGVVVRLDRSSSIIISVDHEFWGRTQGLCGLYNGRPEDDFVEPGGGLAMLAATFGNSWRLPGYEPGCLDTVEVARGCEGLLEGTLTGLEAGKLQAQAQDLCHQLLEDPFSQCHGQVPPDEYHETCLFAYCVGATAGSGPEEQVKAVCATFANYAQACARQHIYVHWRKPGFCERLCPGGQLYSDCISSCPPSCSAVAQGEEGSCGKECVSGCECPTGLFWDGALCVPAAHCPCYYRRQRYAPGDTVKQQCNPCVCQDGRWHCAQAPCPAECAVGGDGHYCTFDGRSFSFRGNPGCQYSLVQDSVKGQLLVVLEHGACETGSCLHALSAFLGKTHIQLRYSGAVLVDGQDVDLPWIGAEGFNVSHASSTFLLLRWPGAWVLWGVADPAVYITLDPRHAYQVQGLCGTFTWKQQDDFLTPAGDIETSVTAFASKFQVSGDGRCPLVDNTPLSSCSTYSQRLAFAEAACAALHGHAFQECHGLVEREPFRLRCLESMCSCAPGRDCLCSVLSAYAHHCAQEGVLLQWRNETLCSVPCPGGQVYQECAPACGHYCGEPEDCKELGSCVAGCNCPPGLLWDLEGQCVPPSMCPCQLGGHRYAFNTTTTLKDCSHCICQERGLWNCIAHHCPRQWALCPQELIYAPGACLLTCDSLGANHSCLAGSTDGCVCPSGTVLLDKHCVSPDLCPCRHNGQWYPPNATIQEDCNICVCQNQRWHCTGQRCSGWCQASGAPHYVTFDGLVFTFPGACEYLLVREAGGRFSVSIQNLPCGASGLTCTKALAVRLDSTVVHMLRGQAVTVNGVSIKLPKVYTGPGLSLHHAGLFLLLTTRLGLTLLWDGGTRVLVQLSPHFHGRVTGLCGNFDGDVSNDLRSRQGVLEPTAELTAHSWRLNPLCPEPGDLPHPCSVNAHRVNWARAHCEVILQPIFAPCHTEVPPQQYYEWCVYDACGCDTGGDCECLCSAIATYADECARHRHHVRWRSQELCPLQCEGGQVYEPCGSTCPPTCHDHHPELRWHCQAITCVEGCFCPEGTLLHGGTCVELTDCPCEWQGSFFPPGAVLQKDCGNCTCQESQWHCNPSGAPCEEMEPGCAEGEALCRESGHCVPLEWLCDNQDDCGDGSDEEGCDTSVCGEGQMSCQSGRCLPLSLICDGQDDCGDGTDEQGCLCPQGFLACADGRCLPPALLCDGHPDCLDAADEESCLGWVSCTSGEVSCVDGPCIRTIQLCDGVWDCPDGADEGPVHCSSPSLPTPPAGIGQNPSTSSPDTSPSPVGSASPASPCSLSEFQCNSGECTPRGWRCDREEDCTDGSDELDCGGPCKLYQMPCAHGPHCLSPGQLCDGVAQCPDGSDEDPDVCEERSASGGPNGTAVPCPEFSCPNGTCIDFLLVCDGSPDCELADETEPSLDEQGCGTWGSWGPWEPCSQTCGPGIQSRNRNCSISSLHVLQNCPGLQHQSQSCFTEACPVDGEWSSWSLWSPCSEPCGGTMTRHRQCRPPQNGGQDCALLPGSTHSTHQTSPCPQEGCLNVTCFGELVFRPCAPCPLTCDDISGEAVCSPDRPCSSPGCWCPEGKVLGTEGRCVRPRQCPCLVDGIRYWPGQRIKMDCQLCFCQDGQPHRCRPNPECAVDCGWSSWSPWAECLGPCSSQSLQWSFRSPNNPRLSGHGRQCRGIHRKARRCQTEPCEGCEQWGLTYHVGERWRGGPCTVCECLHRSITRCSPYCPIGSCPQSWVLVEGMGESCCHCALPGKNQTMIPVTTPAPVPTPSPQIGASLVTYVLPPMSDACYSPLGLAGLPTWAPSQPLEHSTRAAPVEAPTAGPGPREDAYAEWHTQPLYLQLDLLWPRNLTGIMVQRAGSSAAYISNLSLQFSSDGLQWHSVLNSLSSTLPPPKPSPESSNHMVPEVWTFDQMVQARYIRVWPHGSHLRDNNQQDIFLWVELLGCKPVPPLAPLCPGTRHRCANGDCALKGGPCDGAVDCEDGSDEEGCGPLRASTASRVHSTARTPALSPTQPGKFPFHPREGLADMEHQQPKQESPMPSAGVSPSASEGLLPVSGQSMQTLTTTSTFPPGLKSLHPGMAAVTVHSPHSVMPGTPVGQSVSPRPFPLMRCGPGQVPCDVLGCVEQEQLCDGREDCLDGSDEQHCASPEPFTVPTTALPGLPASRALCSPSQLSCGSGECLPLEHRCDLQVNCQDGSDEDDCVDCVLAPWSGWSDCSRSCGLGLIFQHRELLRPPLPGGSCLLDQLRSQPCFVQACPVAGAWAKWGPWEPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGPSHEKVLCNLQLCPGDTDCEPGRVHVNAELCQKGLLPPCPPSCLDPEANRSCSGHCVEGCRCPPGLFLQDSHCLPLSECPCLVGQKLMQPGLAFLLDNCSQCICESGILLCKPAACSQSCGWSAWSPWTACDHSCGSGVRARFRSPTNPPAAFGGSPCEGDRQELQACYTDCGTDIPGWTPWTSWSSCSQSCLVPGGDPGRRQRSRLCPSSRDTFCPGEATQEEPCSPSLCPVPSAWGLWASWSACSASCNGGIQTRGRSCSGSAPGNPVCLGPHTQTRDCNVHPCTAQCPGNMVFRSAEKCLEEGGPCPQLCLAQDPGVECTGSCAPGCSCPPGLFLHNASCLPRSQCPCQLHGQLYAPGAVARLDCNNCTCSSGEMVCTSERCPVACGWSPWTPWSPCSQSCNVGIRRRFRAGTAPPAAFGGAECRGPNLDAEFCTLRPCQGPGAAWSSWTPCSVPCGGGYRNRTQGSGRHSPVEFSTCSLQPCAGPVPGVCPKDQQWLDCAQGPASCAHLSTPREANQTCHPGCYCLSGMLLLNNVCVPAQDCPCAHRGRLHSPGSAVILPCENCSCVSGLITNCSSWPCEEGQPAWSSWTPWSVCSASCSPARRHRRRFCVRPSTTAPFSLDLPTTVAAPTMLCPGPEAEEEPCLLPGCNQAGVWGPWSPWSGCSRSCGGGLRSRTRACDKPPPQGLGDFCEGPQAQGEACQAQPCPVANCSTIEGAEYSPCGPPCPRSCDDLVHCMWHCQPGCYCPPGKVLSADGAICVQPHHCSCLDLLTGKRHHPGSQLMRPDGCNHCTCMEGRLNCTDLPCQVSGDWCPWSEWTACSQPCRGQTRTRSRACVCPAPQHGGAPCPEEAGETGVQHQMEACPNPTACPVDGAWSPWGSWSPCDACLGQSYRSRMCSHPPPSDGGTPCLGGHQQSRPCRNSSTPCTDCGGGQDLLPCGQPCPHSCQDLSLGSTCQPGSSGCQSGCGCPPGQLSQDGLCVFPADCHCHFQPKAMGIPENQSRSVGSALSSWESLEPGEVVTGPCDNCTCVAGVLQCHEVPSCPGPGIWSSWGPWEKCSVPCGGGEQLRSRQCARPPCPGLAQQSRTCHIHVCRETGCPAGRLYRECQPSEGCPFSCAHVTGQVACFSESCEEGCHCPEGTFQHHSACVQECPCVLTVSLLQELGVASTALRSYPVLLGDEGQPLGPGDELDPGQMLQTVCGNCSCVHGKLSCSMEECSRVRGYFGPWGMWSLCSHSCGGLGTRTRTRQCVLPTLAPAGLSCRGPLQDLEYCFSPECPGTAGSTVEPVTGLAGGWGPWSPWSPCSHSCTDLTHPAWRSRTRLCLANCTVGDSSQERPCNLPSCTTLPLCPGPGCGSENCFWTSWAPWEPCSRSCGVGQQRRLRAYHPPGPGGHWCPDILTAYQERRFCNLRACPVPGGWSHWSPWSWCDRSCGGGRSLRSRSCSSPPPKNGGASCVGERHHVRSCNPMPCEKDCPAGMEMVSCANRCPYSCSDLQEAVMCQEDQACQLGCRCSEGFLEQDGGCVPVGHCECTDAQGRSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPAHCAWSHWSAWSACSHSCGPHGQQSRFRSSTSGSWALECQKEQSQSQPCPEDPCPPLCLHEAHLHVLGDNWLHGECQQCSCTPEGVICKDTDCAVPGGWTLWSSWSYCSVSCGGGSQVRTRSCMVSAPQHGSPSCQGPDTQTQHCGQQLCLQLLEICSWGPWGPCSRSCGTGLASRSGSCPCLLTKEDSECNDTFSGLDTQACYPGPCQEDCMWSDWSSWTRCSCKILVQQRYRHQVPAPGQAGEGTLCTGLDGHFRPCAIGNCSEDSCLPPFEFQSCGSPCAGLCATHLSHQLCQDLPPCQPGCYCPMGLLEQDGGCILPEQCNCWHTSGEGARVTLAPGHRLQLGCKECVCQSGELQCSSQGCEGLLPLTGWSEWSPCGPCLPQSALAPDSRTALEVHWPLNTSVTLLASEQYRHRLCLDPETGRPWAGDPALCTVPLSQQRLCSDPGACHDTCQWGPWGPWSPCQVPCSGGFKLRWREASDNSVGECRGPWAQTESCNMGSCPGESCETRDTVFTLDCANQCPRSCADLWEGVQCLQGPCSPGCRCPPGQLVQDGHCVPISSCRCGLPSANASWELAPTQVVQLDCHNCTCINGTLMCPYPECPVLGPWSPWSECSAVCGGGTMVRYRSCEEHPDSAPCQALDMEQRVECNLQTCPECPPGQVLSTCATLCPSFCSHLWPGTICVREPCQLGCGCPGGQLLHSGTCIPPEACPCTRLSLPWGLTLPLEEQAQELPSGTVLTWNCTHCTCQGGVFTCSHTDCQECPPGEILQLGELRPCEKTCLEMNKTQAWSNCTEAQVPGCVCQLGHFRSHTGLCVPEDHCECWHHGSPHLPGSEWQEACESCRCLHGKSVCTQHCPELSCAQGEVVVQEPGSCCPICQQDTLEEEPVSCRHLTELRNLTKGPCHLDQVEVSYCSGHCRSSTNVMTEEPYLQSQCDCCSYRLDPDSPVRILNLLCPDGRTEPVLLPVIHNCHCSACQGGEFSKH" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A2VEC9/", "id": "A2VEC9", "database": "OMA" } ], "organism": "Rattus norvegicus", "tax_id": 10116 } ], "refseq": { "url": "", "ac": "", "name": "", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030414", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9", "id": "A2VEC9", "database": "UniProtKB" } ], "name": "peptidase inhibitor activity", "id": "GO:0030414" } ], "total": 1, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9", "id": "A2VEC9", "database": "UniProtKB" } ], "name": "extracellular space", "id": "GO:0005615" } ], "total": 1, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9", "id": "A2VEC9", "database": "UniProtKB" } ], "name": "cell adhesion", "id": "GO:0007155" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9", "id": "A2VEC9", "database": "UniProtKB" } ], "name": "nervous system development", "id": "GO:0007399" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2VEC9", "id": "A2VEC9", "database": "UniProtKB" } ], "name": "cell differentiation", "id": "GO:0030154" } ], "total": 3, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 90, "annotation": "n_glycosylation_sequon", "start_pos": 88 }, { "end_pos": 132, "annotation": "n_glycosylation_sequon", "start_pos": 130 }, { "end_pos": 263, "annotation": "n_glycosylation_sequon", "start_pos": 261 }, { "end_pos": 517, "annotation": "n_glycosylation_sequon", "start_pos": 515 }, { "end_pos": 822, "annotation": "n_glycosylation_sequon", "start_pos": 820 }, { "end_pos": 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"start_pos": 5064 } ], "crossref": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5173214", "id": "R-HSA-5173214", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5083635", "id": "R-HSA-5083635", "database": "Reactome" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000197558", "id": "ENSG00000197558", "database": "Bgee" }, { "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=21998", "id": "21998", "database": "HGNC" }, { "url": "https://omabrowser.org/oma/group/MQTKNEL/", "id": "MQTKNEL", "database": "OMA" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00057", "id": "cd00057", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "id": "cd00112", "database": "CDD" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR030119", "id": "IPR030119", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036201", "id": 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"https://www.ebi.ac.uk/interpro/entry/IPR001846", "id": "IPR001846", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "id": "IPR002919", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "id": "IPR014853", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "id": "IPR036084", "database": "InterPro" }, { "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=SSPO", "id": "SSPO", "database": "GeneCards" }, { "url": "http://pfam.xfam.org/family/PF00090", "id": "PF00090", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00754", "id": "PF00754", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00057", "id": "PF00057", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00094", "id": "PF00094", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF01826", "id": "PF01826", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF08742", "id": "PF08742", "database": "Pfam" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF358", "id": "PTHR11339:SF358", "database": "PANTHER" }, { "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2VEC9", "id": "PR_A2VEC9", "database": "PRO" }, { "url": "https://www.nextprot.org/entry/NX_A2VEC9", "id": "NX_A2VEC9", "database": "neXtProt" }, { "url": "https://www.ebi.ac.uk/intact/interactors/id:A2VEC9*", "id": "A2VEC9", "database": "IntAct" } ], "expression_disease": [], "uniprot_ac": "A2VEC9", "disease": [], "mass": { "monoisotopic_mass": 547841.0, "chemical_mass": 547841.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=21998", "name": "SSPO", "locus": { "end_pos": 149833979, "start_pos": 149776042, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSG00000197558", "id": "ENSG00000197558", "database": "Ensembl Gene" } ] } } ] }