{ "uniprot_canonical_ac": "A2AIR5-1", "sequence": { "length": 1135, "sequence": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQDGGRAGAQRDEPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGTETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESIINITANLSSTKDLLSFLQVQLENIRNSTPTMVMFGCDMGSIRQIFEMSTQFGLSPPDLHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIVSSENNFFIWNLQYDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFHHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSILDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPCSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNMGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQTHQDIPLPPRRRELPASLTTNGKADSLNVARNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTNRTCES" }, "uniprot_id": "A2AIR5_MOUSE", "enzyme_annotation": [], "alternativenames": [], "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "recommendedname": {}, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5#A2AIR4-1", "isoform_ac": "A2AIR4-1", "locus": { "end_pos": 49665229, "start_pos": 49845081, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000076674", "id": "ENSMUST00000076674", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000075970", "id": "ENSMUSP00000075970", "database": "Ensembl Peptide" } ] }, "sequence": { "length": 1115, "sequence": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQDGGRAGAQRDEPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGTETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESIINITANLSSTKDLLSFLQVQLENIRNSTPTMVMFGCDMGSIRQIFEMSTQFGLSPPDLHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIVSSENNFFIWNLQYDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFHHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSILDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPCSKTKRVEKRSNMGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQTHQDIPLPPRRRELPASLTTNGKADSLNVARNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTNRTCES" } }, { "url": "https://www.uniprot.org/uniprot/A2AIR5#A2AIR5-1", "isoform_ac": "A2AIR5-1", "locus": { "end_pos": 49665229, "start_pos": 49845081, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000093859", "id": "ENSMUST00000093859", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000091381", "id": "ENSMUSP00000091381", "database": "Ensembl Peptide" } ] }, "sequence": { "length": 1135, "sequence": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQDGGRAGAQRDEPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGTETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESIINITANLSSTKDLLSFLQVQLENIRNSTPTMVMFGCDMGSIRQIFEMSTQFGLSPPDLHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIVSSENNFFIWNLQYDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFHHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSILDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPCSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNMGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQTHQDIPLPPRRRELPASLTTNGKADSLNVARNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTNRTCES" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9609736", "resource": "Reactome", "id": "R-MMU-9609736", "name": "Assembly and cell surface presentation of NMDA receptors" } ], "function": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", "annotation": "In the prefrontal cortex of GluN3A knock-out mice, the expression of the oxytocin receptor was significantly lower.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", "id": "NP_001263284.1", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", "annotation": "This study for the first time provides insights into transcriptome changes upon the specific knockdown of an NMDAR subunit in NSCs, which may help to identify additional functions and downstream pathways of GluN3A and GluN3A-containing NMDARs Publication Status: Online-Only", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", "id": "NP_001263284.1", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", "annotation": "Results implicate GluN3A reactivation in a broad spectrum of early-stage synaptic transmission deficits in YAC128 mice", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", "id": "NP_001263284.1", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", "annotation": "Decrease in NMDA-receptor activity in alpha-neurexin-deficient synapses", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", "id": "NP_001263284.1", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q9R1M7-1", "protein_name": "Glutamate receptor ionotropic, NMDA 3A", "sequence": { "length": 1135, "sequence": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQEGGRAGAQRDDPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGAETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESVINITANLSSTKDLLSFLQVQMDNIRNSTPTMVMFGCDMDSIRQIFEMSTQFGLSPPELHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIISSENNFFIWNLQHDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFQHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVHRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPRSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNLGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQAHQDIPLPQRRRELPASLTTNGKADSLNVTRSSVIQELSELEKQIQVIRQELQLAVSRKTELEEYQKTNRTCES" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/128613", "id": "128613", "database": "MGI" } ], "organism": "Rattus norvegicus", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q8TCU5-1", "protein_name": "Glutamate receptor ionotropic, NMDA 3A", "sequence": { "length": 1115, "sequence": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAPDDSRAGAQRDEPEPGTRRSPAPSPGARWLGSTLHGRGPPGSRKPGEGARAEALWPRDALLFAVDNLNRVEGLLPYNLSLEVVMAIEAGLGDLPLLPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSLVLHIPVISIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTQNNSKFHLGSIINITANLPSTQDLLSFLQIQLESIKNSTPTVVMFGCDMESIRRIFEITTQFGVMPPELRWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEHYVQDAMELVARAVATATMIQPELALIPSTMNCMEVETTNLTSGQYLSRFLANTTFRGLSGSIRVKGSTIVSSENNFFIWNLQHDPMGKPMWTRLGSWQGGKIVMDYGIWPEQAQRHKTHFQHPSKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSTLDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEKIAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLRGTAHMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAVFLTLYEWKSPFGLTPKGRNRSKVFSFSSALNICYALLFGRTVAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVEYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTANISELISQYKSHGFMDMLHDKWYRVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRLHRAINTSFIEEKQQHFKTKRVEKRSNVGPRQLTVWNTSNLSHDNRRKYIFSDEEGQNQLGIRIHQDIPLPPRRRELPALRTTNGKADSLNVSRNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTSRTCES" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/128613", "id": "128613", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", "ac": "NP_001263284.1", "name": "glutamate receptor ionotropic, NMDA 3A isoform 1 precursor", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "calcium channel activity", "id": "GO:0005262" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "identical protein binding", "id": "GO:0042802" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051721", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "protein phosphatase 2A binding", "id": "GO:0051721" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004970", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "ionotropic glutamate receptor activity", "id": "GO:0004970" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016594", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "glycine binding", "id": "GO:0016594" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008066", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "glutamate receptor activity", "id": "GO:0008066" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004972", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "NMDA glutamate receptor activity", "id": "GO:0004972" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042165", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "neurotransmitter binding", "id": "GO:0042165" } ], "total": 9, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "glutamatergic synapse", "id": "GO:0098978" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017146", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "NMDA selective glutamate receptor complex", "id": "GO:0017146" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "plasma membrane", "id": "GO:0005886" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "membrane", "id": "GO:0016020" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "cell junction", "id": "GO:0030054" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "neuronal cell body", "id": "GO:0043025" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "synapse", "id": "GO:0045202" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "postsynaptic membrane", "id": "GO:0045211" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "neuron projection", "id": "GO:0043005" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "postsynaptic density membrane", "id": "GO:0098839" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099061", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "integral component of postsynaptic density membrane", "id": "GO:0099061" } ], "total": 11, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "dendrite development", "id": "GO:0016358" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035235", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "ionotropic glutamate receptor signaling pathway", "id": "GO:0035235" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045471", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "response to ethanol", "id": "GO:0045471" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "calcium ion transport", "id": "GO:0006816" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "synaptic transmission, glutamatergic", "id": "GO:0035249" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060134", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "prepulse inhibition", "id": "GO:0060134" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "rhythmic process", "id": "GO:0048511" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "modulation of chemical synaptic transmission", "id": "GO:0050804" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000300", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AIR5", "id": "A2AIR5", "database": "UniProtKB" } ], "name": "regulation of synaptic vesicle exocytosis", "id": "GO:2000300" } ], "total": 9, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 147, "annotation": "n_glycosylation_sequon", "start_pos": 145 }, { "end_pos": 266, "annotation": "n_glycosylation_sequon", "start_pos": 264 }, { "end_pos": 277, "annotation": "n_glycosylation_sequon", "start_pos": 275 }, { "end_pos": 287, "annotation": "n_glycosylation_sequon", "start_pos": 285 }, { "end_pos": 298, "annotation": "n_glycosylation_sequon", "start_pos": 296 }, { "end_pos": 302, "annotation": "n_glycosylation_sequon", "start_pos": 300 }, { "end_pos": 322, "annotation": "n_glycosylation_sequon", "start_pos": 320 }, { "end_pos": 428, "annotation": "n_glycosylation_sequon", "start_pos": 426 }, { "end_pos": 441, "annotation": "n_glycosylation_sequon", "start_pos": 439 }, { "end_pos": 551, "annotation": "n_glycosylation_sequon", "start_pos": 549 }, { "end_pos": 567, "annotation": "n_glycosylation_sequon", "start_pos": 565 }, { "end_pos": 888, "annotation": "n_glycosylation_sequon", "start_pos": 886 }, { "end_pos": 967, "annotation": "n_glycosylation_sequon", "start_pos": 965 }, { "end_pos": 986, "annotation": "n_glycosylation_sequon", "start_pos": 984 }, { "end_pos": 1037, "annotation": "n_glycosylation_sequon", "start_pos": 1035 }, { "end_pos": 1040, "annotation": "n_glycosylation_sequon", "start_pos": 1038 }, { "end_pos": 1132, "annotation": "n_glycosylation_sequon", "start_pos": 1130 } ], "crossref": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9609736", "id": "R-MMU-9609736", "database": "Reactome" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000039579", "id": "ENSMUSG00000039579", "database": "Bgee" }, { "url": "http://www.informatics.jax.org/marker/MGI:1933206", "id": "1933206", "database": "MGI" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "id": "IPR001828", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "id": "IPR028082", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001320", "id": "IPR001320", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001508", "id": "IPR001508", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR019594", "id": "IPR019594", "database": "InterPro" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/242443", "id": "242443", "database": "GeneID" }, { "url": "http://pfam.xfam.org/family/PF01094", "id": "PF01094", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00060", "id": "PF00060", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF10613", "id": "PF10613", "database": "Pfam" } ], "expression_disease": [], "uniprot_ac": "A2AIR5", "disease": [], "mass": { "monoisotopic_mass": 127542.0, "chemical_mass": 127542.0 }, "expression_tissue": [], "gene": [ { "url": "http://www.informatics.jax.org/marker/MGI:1933206", "name": "Grin3a", "locus": { "end_pos": 49661611, "start_pos": 49845744, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000039579", "id": "ENSMUSG00000039579", "database": "Ensembl Gene" } ] } } ] }