{
    "uniprot_canonical_ac": "A1L1L2-1", 
    "sequence": {
        "length": 685, 
        "sequence": "MAARAAGSGGWEVVKRSRRPGASSGGRGGGGDRRALGEANGVWKYDLSSPIQPTSTLYERGFEKIMKRQNKEQVPPPAAESKKPVNKKQPKKVTAVASQNQKQGPFRSLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKSLSPFAIAYLDRLLLMYPNLTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLTSWEQIPKKARKCLQETIQSFTLTNQELLKKGSGSNEHVVTCDTACKGLLQQARGPRPPWARLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLQSSGLLPVAQQVCAKLYSYSLQSYNWLQETLPACGSYLLAVVQPSLQLAWTYIYATFSFLSAYCASYLAFFSDSLAGVLQRVQLPEALHQLFHSLKELLLLFYHSVLLPMWHLLLAALAQVQEHCHEACRGEMTWDCIKTQFSTAAHWTWLCLQDVTVAFLDWALTMISQQ"
    }, 
    "uniprot_id": "TM214_RAT", 
    "enzyme_annotation": [], 
    "alternativenames": [], 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L1L2", 
                    "id": "A1L1L2", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Transmembrane protein 214"
    }, 
    "publication": [], 
    "glycosylation": [
        {
            "residue": "Asn", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L1L2#ptm_processing", 
                    "id": "A1L1L2-1", 
                    "database": "UniProtKB"
                }
            ], 
            "relation": "attached", 
            "position": 267, 
            "glytoucan_ac": "GlcNAc...", 
            "type": "N-linked"
        }, 
        {
            "residue": "Asn", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L1L2#ptm_processing", 
                    "id": "A1L1L2-1", 
                    "database": "UniProtKB"
                }
            ], 
            "relation": "attached", 
            "position": 305, 
            "glytoucan_ac": "GlcNAc...", 
            "type": "N-linked"
        }
    ], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L1L2#A1L1L2-1", 
            "isoform_ac": "A1L1L2-1", 
            "locus": {
                "end_pos": 26868380, 
                "start_pos": 26875333, 
                "chromosome": "6", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000011838", 
                        "id": "ENSRNOT00000011838", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000011838", 
                        "id": "ENSRNOP00000011838", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "length": 685, 
                "sequence": "MAARAAGSGGWEVVKRSRRPGASSGGRGGGGDRRALGEANGVWKYDLSSPIQPTSTLYERGFEKIMKRQNKEQVPPPAAESKKPVNKKQPKKVTAVASQNQKQGPFRSLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKSLSPFAIAYLDRLLLMYPNLTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLTSWEQIPKKARKCLQETIQSFTLTNQELLKKGSGSNEHVVTCDTACKGLLQQARGPRPPWARLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLQSSGLLPVAQQVCAKLYSYSLQSYNWLQETLPACGSYLLAVVQPSLQLAWTYIYATFSFLSAYCASYLAFFSDSLAGVLQRVQLPEALHQLFHSLKELLLLFYHSVLLPMWHLLLAALAQVQEHCHEACRGEMTWDCIKTQFSTAAHWTWLCLQDVTVAFLDWALTMISQQ"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:362711", 
            "resource": "KEGG Pathway", 
            "id": "rno:362711", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L1L2#function", 
            "annotation": "Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L1L2#function", 
                    "id": "A1L1L2", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q8BM55-1", 
            "protein_name": "Transmembrane protein 214", 
            "sequence": {
                "length": 687, 
                "sequence": "MAARSAGSGGWEVVKRGRRPGASSGGRGGGGGSDRRALGEANGVLKYDLSSPIQTTSTLYERGFEKIMKRQNKEQVPPPAAESKKPINKKQPKKVTAVPSQNQKQGPFRRLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAVLQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKALSPFAIAYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLKSWEHIPKKARKSLQETIQSLKVTNQELLKKGSGGSEHVLTCDTACKGLLQRARGPRPPWARLFLLLLVFAVGFLCHDLRSNSSLQASLTGRLLRSSGLLPVGQQVCARLSSYSLQSYNWLQETLPACGSHLLAVVQPSLQLAWTHIYAIFSFLSAHCASYLACFSDSLAGFFQRVQLPEALQQLFHALKELLLLFCHSVLLPTWHLLLAALAQVQEHCHEACRGDVTWDCIKTQLSRAAQWTWLCLQDVTVAFLDWALTMISQQ"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A1L1L2/", 
                    "id": "A1L1L2", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/9801", 
                    "id": "9801", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q6NUQ4-1", 
            "protein_name": "Transmembrane protein 214", 
            "sequence": {
                "length": 689, 
                "sequence": "MATKTAGVGRWEVVKKGRRPGVGAGAGGRGGGRNRRALGEANGVWKYDLTPAIQTTSTLYERGFENIMKRQNKEQVPPPAVEPKKPGNKKQPKKVATPPNQNQKQGRFRSLEEALKALDVADLQKELDKSQSVFSGNPSIWLKDLASYLNYKLQAPLSEPTLSQHTHDYPYSLVSRELRGIIRGLLAKAAGSLELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIATANLGKFLELLRSHQSRPAKCLTIMWALGQAGFANLTEGLKVWLGIMLPVLGIKSLSPFAITYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLTPSLQEQLCQLYPRLKVLAFGAKPDSTLHTYFPSFLSRATPSCPPEMKKELLSSLTECLTVDPLSASVWRQLYPKHLSQSSLLLEHLLSSWEQIPKKVQKSLQETIQSLKLTNQELLRKGSSNNQDVVTCDMACKGLLQQVQGPRLPWTRLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLRSSGFLPASQQACAKLYSYSLQGYSWLGETLPLWGSHLLTVVRPSLQLAWAHTNATVSFLSAHCASHLAWFGDSLTSLSQRLQIQLPDSVNQLLRYLRELPLLFHQNVLLPLWHLLLEALAWAQEHCHEACRGEVTWDCMKTQLSEAVHWTWLCLQDITVAFLDWALALISQQ"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/9801", 
                    "id": "9801", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014217.2", 
        "ac": "NP_001014217.2", 
        "name": "transmembrane protein 214", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1L2", 
                                "id": "A1L1L2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "endoplasmic reticulum", 
                        "id": "GO:0005783"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1L2", 
                                "id": "A1L1L2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Golgi apparatus", 
                        "id": "GO:0005794"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1L2", 
                                "id": "A1L1L2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytosol", 
                        "id": "GO:0005829"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1L2", 
                                "id": "A1L1L2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1L2", 
                                "id": "A1L1L2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "endoplasmic reticulum membrane", 
                        "id": "GO:0005789"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1L2", 
                                "id": "A1L1L2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasmic microtubule", 
                        "id": "GO:0005881"
                    }
                ], 
                "total": 6, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L1L2", 
                                "id": "A1L1L2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "apoptotic process", 
                        "id": "GO:0006915"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 269, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 267
        }, 
        {
            "end_pos": 307, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 305
        }, 
        {
            "end_pos": 331, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 329
        }
    ], 
    "crossref": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:362711", 
            "id": "rno:362711", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000008812", 
            "id": "ENSRNOG00000008812", 
            "database": "Bgee"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1311324", 
            "id": "1311324", 
            "database": "RGD"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/VKHANIF/", 
            "id": "VKHANIF", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019308", 
            "id": "IPR019308", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/362711", 
            "id": "362711", 
            "database": "GeneID"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF10151", 
            "id": "PF10151", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13448", 
            "id": "PTHR13448", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A1L1L2", 
            "id": "PR_A1L1L2", 
            "database": "PRO"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A1L1L2", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 76566.0, 
        "chemical_mass": 76566.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1311324", 
            "name": "Tmem214", 
            "locus": {
                "end_pos": 26866737, 
                "start_pos": 26875376, 
                "chromosome": "6", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000008812", 
                        "id": "ENSRNOG00000008812", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}