{
    "uniprot_canonical_ac": "A2RUT3-1", 
    "synonyms_protein_refseq": [
        "transmembrane protein 89 precursor"
    ], 
    "sequence": {
        "header": "sp|A2RUT3-1|TMM89_HUMAN Isoform 1 of Transmembrane protein 89  OS=Homo sapiens OX=9606 GN=TMEM89 PE=2 SV=1 CANONICAL=A2RUT3-1", 
        "length": 159, 
        "sequence": "MLHVLASLPLLLLLVTSASTHAWSRPLWYQVGLDLQPWGCQPKSVEGCRGGLSCPGYWLGPGASRIYPVAAVMITTTMLMICRKILQGRRRSQATKGEHPQVTTEPCGPWKRRAPISDHTLLRGVLHMLDALLVHIEGHLRHLATQRQIQIKGTSTQSG"
    }, 
    "uniprot_id": "TMM89_HUMAN", 
    "synonyms_gene_uniprotkb": [
        "TMEM89"
    ], 
    "enzyme_annotation": [], 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RUT3", 
                    "id": "A2RUT3", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Transmembrane protein 89", 
        "short": ""
    }, 
    "publication": [
        {
            "title": "Proteomic characterization of the human sperm nucleus.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/21630459", 
            "journal": "Proteomics", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008270.1", 
                    "id": "NP_001008270.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "de Mateo S, Castillo J, Estanyol JM, Ballesca JL, Oliva R", 
            "date": "2011", 
            "pmid": "21630459"
        }
    ], 
    "uniprot_ac": "A2RUT3", 
    "synonyms_gene_refseq": [
        "TMEM89"
    ], 
    "mutation": [
        {
            "sequence_org": "L", 
            "subjects_tested": "50", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid gland cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUT3", 
                    "id": "A2RUT3", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "sequence_mut": "Q", 
            "start_pos": 86, 
            "end_pos": 86, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%)."
        }, 
        {
            "sequence_org": "L", 
            "subjects_tested": "50", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid gland cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUT3", 
                    "id": "A2RUT3", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "sequence_mut": "S", 
            "start_pos": 35, 
            "end_pos": 35, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%)."
        }
    ], 
    "synonyms_protein_uniprotkb": [
        "Transmembrane protein 89"
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RUT3#A2RUT3-1", 
            "isoform_ac": "A2RUT3-1", 
            "locus": {
                "end_pos": 48620845, 
                "start_pos": 48621756, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000330862", 
                        "id": "ENST00000330862", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000329557", 
                        "id": "ENSP00000329557", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2RUT3-1|TMM89_HUMAN Isoform 1 of Transmembrane protein 89  OS=Homo sapiens OX=9606 GN=TMEM89 PE=2 SV=1 CANONICAL=A2RUT3-1", 
                "length": 159, 
                "sequence": "MLHVLASLPLLLLLVTSASTHAWSRPLWYQVGLDLQPWGCQPKSVEGCRGGLSCPGYWLGPGASRIYPVAAVMITTTMLMICRKILQGRRRSQATKGEHPQVTTEPCGPWKRRAPISDHTLLRGVLHMLDALLVHIEGHLRHLATQRQIQIKGTSTQSG"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:440955", 
            "resource": "KEGG Pathway", 
            "id": "hsa:440955", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9DA04-1", 
            "protein_name": "Transmembrane protein 89", 
            "sequence": {
                "length": 169, 
                "sequence": "MLYTLLLVPSLFLLVMPVPSQGWSRPLWYQVGLDLQPWGCQPNSPDIWGCQPNSLDSCKNSLGCPGYWLGLGGNRIYPVAGVTITTTMLLVVSRVIVHRWRAKVAKGQLPAVTSSSGKHWKEQPTVSDRTLVLRVLHMLDAILLHIEGHLQGLASQQQIQIKGSPPQSG"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/52857", 
                    "id": "52857", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "synthesized_glycans": [], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008270.1", 
        "ac": "NP_001008270.1", 
        "name": "transmembrane protein 89 precursor", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUT3", 
                                "id": "A2RUT3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUT3", 
                                "id": "A2RUT3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.nextprot.org/entry/NX_A2RUT3", 
            "id": "NX_A2RUT3", 
            "database": "neXtProt"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A2RUT3*", 
            "id": "A2RUT3", 
            "database": "IntAct"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A2RUT3", 
            "id": "A2RUT3", 
            "database": "PHAROS"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
            "id": "ENSG00000183396", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008270.1", 
            "id": "NP_001008270.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/440955", 
            "id": "440955", 
            "database": "GeneID"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2RUT3", 
            "id": "PR_A2RUT3", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028069", 
            "id": "IPR028069", 
            "database": "InterPro"
        }, 
        {
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUT3", 
            "id": "A2RUT3", 
            "database": "BioMuta"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:440955", 
            "id": "hsa:440955", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF15098", 
            "id": "PF15098", 
            "database": "Pfam"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/CPGHWMG/", 
            "id": "CPGHWMG", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1413701at2759", 
            "id": "1413701at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37869", 
            "id": "PTHR37869", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=32372", 
            "id": "32372", 
            "database": "HGNC"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=TMEM89", 
            "id": "TMEM89", 
            "database": "GeneCards"
        }
    ], 
    "expression_disease": [
        {
            "name": "Esophageal cancer [DO disease name]", 
            "trend": "Down", 
            "icd10": "C15.3", 
            "disease": {
                "doid": "5041", 
                "url": "http://disease-ontology.org/term/DOID:5041", 
                "icd10": "", 
                "name": "Esophageal cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUT3", 
                    "id": "A2RUT3", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:5041", 
            "significant": "No"
        }, 
        {
            "name": "Lung squamous cell carcinoma [DO disease name]", 
            "trend": "Up", 
            "disease": {
                "doid": "3907", 
                "url": "http://disease-ontology.org/term/DOID:3907", 
                "icd10": "", 
                "name": "Lung squamous cell carcinoma"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUT3", 
                    "id": "A2RUT3", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3907", 
            "significant": "No"
        }, 
        {
            "name": "Lung adenocarcinoma [DO disease name]", 
            "trend": "Down", 
            "disease": {
                "doid": "3910", 
                "url": "http://disease-ontology.org/term/DOID:3910", 
                "icd10": "", 
                "name": "Lung adenocarcinoma"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUT3", 
                    "id": "A2RUT3", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3910", 
            "significant": "No"
        }, 
        {
            "name": "Liver cancer [DO disease name]", 
            "trend": "Up", 
            "icd10": "C22.0", 
            "disease": {
                "doid": "3571", 
                "url": "http://disease-ontology.org/term/DOID:3571", 
                "icd10": "", 
                "name": "Liver cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUT3", 
                    "id": "A2RUT3", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3571", 
            "significant": "No"
        }, 
        {
            "name": "Urinary bladder cancer [DO disease name]", 
            "trend": "Down", 
            "icd10": "C67", 
            "disease": {
                "doid": "11054", 
                "url": "http://disease-ontology.org/term/DOID:11054", 
                "icd10": "", 
                "name": "Urinary bladder cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUT3", 
                    "id": "A2RUT3", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:11054", 
            "significant": "No"
        }, 
        {
            "name": "Thyroid gland cancer [DO disease name]", 
            "trend": "Up", 
            "icd10": "C73", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid gland cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUT3", 
                    "id": "A2RUT3", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:1781", 
            "significant": "No"
        }, 
        {
            "name": "Prostate cancer [DO disease name]", 
            "trend": "Up", 
            "icd10": "C61", 
            "disease": {
                "doid": "10283", 
                "url": "http://disease-ontology.org/term/DOID:10283", 
                "icd10": "", 
                "name": "Prostate cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUT3", 
                    "id": "A2RUT3", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:10283", 
            "significant": "No"
        }
    ], 
    "glycosylation": [], 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 17572.0, 
        "chemical_mass": 17572.0
    }, 
    "expression_tissue": [
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001255", 
                "uberon": "0001255", 
                "name": "Urinary bladder"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000955", 
                "uberon": "0000955", 
                "name": "Brain"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002107", 
                "uberon": "0002107", 
                "name": "Liver"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000007", 
                "uberon": "0000007", 
                "name": "Pituitary gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001043", 
                "uberon": "0001043", 
                "name": "Esophagus"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002367", 
                "uberon": "0002367", 
                "name": "Prostate gland"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000473", 
                "uberon": "0000473", 
                "name": "Testis"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001161", 
                "uberon": "0001161", 
                "name": "Body of stomach"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000178", 
                "uberon": "0000178", 
                "name": "Blood"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0009853", 
                "uberon": "0009853", 
                "name": "Body of uterus"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002048", 
                "uberon": "0002048", 
                "name": "Lung"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0009853", 
                "uberon": "0009853", 
                "name": "Body of uterus"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000948", 
                "uberon": "0000948", 
                "name": "Heart"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001150", 
                "uberon": "0001150", 
                "name": "Body of pancreas"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000992", 
                "uberon": "0000992", 
                "name": "Ovary"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000178", 
                "uberon": "0000178", 
                "name": "Blood"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000996", 
                "uberon": "0000996", 
                "name": "Vagina"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001160", 
                "uberon": "0001160", 
                "name": "Fundus of stomach"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001987", 
                "uberon": "0001987", 
                "name": "Placenta"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002046", 
                "uberon": "0002046", 
                "name": "Thyroid gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000458", 
                "uberon": "0000458", 
                "name": "Endocervix"
            }, 
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            "evidence": [
                {
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                    "id": "ENSG00000183396", 
                    "database": "Bgee"
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        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000996", 
                "uberon": "0000996", 
                "name": "Vagina"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
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        {
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                "url": "http://purl.obolibrary.org/obo/UBERON_0002369", 
                "uberon": "0002369", 
                "name": "Adrenal gland"
            }, 
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            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
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                "uberon": "0000458", 
                "name": "Endocervix"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001150", 
                "uberon": "0001150", 
                "name": "Body of pancreas"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001160", 
                "uberon": "0001160", 
                "name": "Fundus of stomach"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001155", 
                "uberon": "0001155", 
                "name": "Colon"
            }, 
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            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000183396", 
                    "id": "ENSG00000183396", 
                    "database": "Bgee"
                }
            ]
        }
    ], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RUT3", 
            "": "", 
            "name": "TMEM89", 
            "locus": {
                "end_pos": 48620759, 
                "start_pos": 48621855, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000183396", 
                        "id": "ENSG00000183396", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}
