{
    "uniprot_canonical_ac": "A2RUB1-4", 
    "synonyms_protein_refseq": [
        "meiosis-specific coiled-coil domain-containing protein MEIOC", 
        "meiosis-specific with coiled-coil domain protein"
    ], 
    "sequence": {
        "header": "sp|A2RUB1-4|MEIOC_HUMAN Isoform 4 of Meiosis-specific coiled-coil domain-containing protein MEIOC  OS=Homo sapiens OX=9606 GN=MEIOC PE=2 SV=3 CANONICAL=A2RUB1-4", 
        "length": 952, 
        "sequence": "MEVRRGDTCPRPHPSGLREEGLEPKVAFPGGANRCWNLGADAGSRLTDVFGSVMLTGSASFYDCYTSQSEDNVDLRQTYTPFSSTEYSSSVDSSLFCAPWSTYGDDIKQPSNSQISIKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFADHHDLLTETKRPIDTVISQQAFYSDESVSAMEKQYLRNSNLTPQQKIDELHHGFTGLDLEEQWMYPSRSDHSNCHNIQTNDTAKTTFQEYPLIKNCFTPQTGLSDIMKESGVDIYHYGRDRICTKGLEAPLQQKRAEMFLSQFNRYNENVDYCRYPEYVHPNKAKLNKCSNFSVQDSKKLANGTPETPTVEADTYTKLFQVKPANQKKMEETIPDQQNFTFPKTTPHLTEKQFAKEAVFTADFGLTSEYGLKPHTACPANDFANVTEKQQFAKPDPPHSEYFKSVNLLSNSATSSGGINLNRPTWMNVQTKNNTPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTPNSNLFQKYCQENPSAFSSFDFSYSGAERIQSVNHIEGLTKPGEENLFKLVTDKKIKQPNGFCDNYSAQKYGIIENVNKHNFQAKPQSGHYDPEEGPKHLDGLSQNTYQDLLESQGHSNSHRTRGGDNSRVNRTQVSCFSNNYMMGDLRHNQCFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLLSYDDLSHLYPYFNMMYGDNSFSGLMPTFGFQRPIKTRSGPASELHIRLEECCEQWRALEKERKKTELALAKNYPGKKVSSTNNTPVPRLTSNPSRVDRLIVDELRELARVVTLLGKMERLRSSLLHASISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALASAIKEMCVATRKTRTALWCALQMTLPKTASTADVVKPLQDTVNCEDKVHESINSSNPMNQRGETNKH"
    }, 
    "uniprot_id": "MEIOC_HUMAN", 
    "synonyms_gene_uniprotkb": [
        "MEIOC", 
        "C17orf104"
    ], 
    "enzyme_annotation": [], 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Meiosis-specific coiled-coil domain-containing protein MEIOC; Meiosis-specific with coiled-coil domain protein", 
        "short": ""
    }, 
    "publication": [
        {
            "title": "Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/26742488", 
            "journal": "Nat. Commun.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "UniProtKB"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138552.2", 
                    "id": "NP_001138552.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Livera G., Martini E., Armengaud J., Toth A., Abby E., Messiaen S., Tourpin S., Daniel K., Gaillard J.C., Guerquin J., Langa F., Moison D., Ribeiro J.", 
            "date": "2016", 
            "pmid": "26742488"
        }, 
        {
            "title": "Meioc maintains an extended meiotic prophase I in mice.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/28380054", 
            "journal": "PLoS Genet.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Page D.C., Kojima M., Godfrey A.K., Mikedis M.M., Soh Y.Q.S., de Rooij D.G.", 
            "date": "2017", 
            "pmid": "28380054"
        }
    ], 
    "uniprot_ac": "A2RUB1", 
    "synonyms_gene_refseq": [
        "MEIOC", 
        "C17orf104"
    ], 
    "mutation": [
        {
            "sequence_org": "R", 
            "subjects_tested": "25", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "10283", 
                "url": "http://disease-ontology.org/term/DOID:10283", 
                "icd10": "", 
                "name": "Prostate cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "4.0", 
            "sequence_mut": "*", 
            "start_pos": 492, 
            "end_pos": 492, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 2 out of 6 filters: patient freq. (4.0%); num. of cancers (3)."
        }, 
        {
            "sequence_org": "R", 
            "subjects_tested": "93", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "2394", 
                "url": "http://disease-ontology.org/term/DOID:2394", 
                "icd10": "", 
                "name": "Ovarian cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.1", 
            "sequence_mut": "*", 
            "start_pos": 492, 
            "end_pos": 492, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 2 out of 6 filters: patient freq. (1.1%); num. of cancers (3)."
        }, 
        {
            "sequence_org": "R", 
            "subjects_tested": "254", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "9256", 
                "url": "http://disease-ontology.org/term/DOID:9256", 
                "icd10": "", 
                "name": "Colorectal cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "0.4", 
            "sequence_mut": "*", 
            "start_pos": 492, 
            "end_pos": 492, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 1 out of 6 filters: num. of cancers (3)."
        }, 
        {
            "sequence_org": "P", 
            "subjects_tested": "93", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "2394", 
                "url": "http://disease-ontology.org/term/DOID:2394", 
                "icd10": "", 
                "name": "Ovarian cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.1", 
            "sequence_mut": "A", 
            "start_pos": 150, 
            "end_pos": 150, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.1%)."
        }, 
        {
            "sequence_org": "T", 
            "subjects_tested": "48", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "2531", 
                "url": "http://disease-ontology.org/term/DOID:2531", 
                "icd10": "", 
                "name": "Hematologic cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.1", 
            "sequence_mut": "A", 
            "start_pos": 949, 
            "end_pos": 949, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.1%)."
        }, 
        {
            "sequence_org": "Q", 
            "subjects_tested": "50", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid gland cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "sequence_mut": "K", 
            "start_pos": 306, 
            "end_pos": 306, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%)."
        }, 
        {
            "sequence_org": "V", 
            "subjects_tested": "50", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid gland cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "sequence_mut": "A", 
            "start_pos": 820, 
            "end_pos": 820, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%)."
        }, 
        {
            "sequence_org": "R", 
            "subjects_tested": "50", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid gland cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "sequence_mut": "K", 
            "start_pos": 772, 
            "end_pos": 772, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%)."
        }, 
        {
            "sequence_org": "P", 
            "subjects_tested": "50", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid gland cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "sequence_mut": "S", 
            "start_pos": 110, 
            "end_pos": 110, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%)."
        }, 
        {
            "sequence_org": "P", 
            "subjects_tested": "63", 
            "subjects_positive": "1", 
            "disease": {
                "doid": "2531", 
                "url": "http://disease-ontology.org/term/DOID:2531", 
                "icd10": "", 
                "name": "Hematologic cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.6", 
            "sequence_mut": "T", 
            "start_pos": 784, 
            "end_pos": 784, 
            "type": "Point mutation", 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.6%)."
        }
    ], 
    "synonyms_protein_uniprotkb": [
        "Meiosis-specific coiled-coil domain-containing protein MEIOC", 
        "Meiosis-specific with coiled-coil domain protein"
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RUB1#A2RUB1-5", 
            "isoform_ac": "A2RUB1-5", 
            "locus": {
                "end_pos": 0, 
                "start_pos": 0, 
                "chromosome": "N/A", 
                "evidence": []
            }, 
            "sequence": {
                "header": "sp|A2RUB1-5|MEIOC_HUMAN Isoform 5 of Meiosis-specific coiled-coil domain-containing protein MEIOC  OS=Homo sapiens OX=9606 GN=MEIOC PE=2 SV=3 CANONICAL=A2RUB1-4", 
                "length": 825, 
                "sequence": "MEVRRGDTCPRPHPSGLREEGLEPKVAFPGGANRCWNLGADAGSRLTDVFGSVMLTGSASFYDCYTSQSEDNVDLRQTYTPFSSTEYSSSVDSSLFCAPWSTYGDDIKQPSNSQISIKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFADHHDLLTETKRPIDTVISQQAFYSDESVSAMEKQYLRNSNLTPQQKIDELHHGFTGLDLEEQWMYPSRSDHSNCHNIQTNDTAKTTFQEYPLIKNCFTPQTGLSDIMKESGVDIYHYGRDRICTKGLEAPLQQKRAEMFLSQFNRYNENVDYCRYPEYVHPNKAKLNKCSNFSVQDSKKLANGTPETPTVEADTYTKLFQVKPANQKKMEETIPDQQNFTFPKTTPHLTEKQFAKEAVFTADFGLTSEYGLKPHTACPANDFANVTEKQQFAKPDPPHSEYFKSVNLLSNSATSSGGINLNRPTWMNVQTKNNTPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTPNSNLFQKYCQENPSAFSSFDFSYSGAERIQSVNHIEGLTKPGEENLFKLVTDKKIKQPNGFCDNYSAQKYGIIENVNKHNFQAKPQSGHYDPEEGPKHLDGLSQNTYQDLLESQGHSNSHRTRGGDNSRVNRTQVSCFSNNYMMGDLRHNQCFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLLSYDDLSHLYPYFNMMYGDNSFSGLMPTFGFQRPIKTRSGPASELHIRLEECCEQWRALEKERKKTELALAKNYPGKKVSSTNNTPVPRLTSNPSRVDRLIVDELRELARVSCKNR"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RUB1#A2RUB1-4", 
            "isoform_ac": "A2RUB1-4", 
            "locus": {
                "end_pos": 44656614, 
                "start_pos": 44674193, 
                "chromosome": "17", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000409122", 
                        "id": "ENST00000409122", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000386452", 
                        "id": "ENSP00000386452", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2RUB1-4|MEIOC_HUMAN Isoform 4 of Meiosis-specific coiled-coil domain-containing protein MEIOC  OS=Homo sapiens OX=9606 GN=MEIOC PE=2 SV=3 CANONICAL=A2RUB1-4", 
                "length": 952, 
                "sequence": "MEVRRGDTCPRPHPSGLREEGLEPKVAFPGGANRCWNLGADAGSRLTDVFGSVMLTGSASFYDCYTSQSEDNVDLRQTYTPFSSTEYSSSVDSSLFCAPWSTYGDDIKQPSNSQISIKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFADHHDLLTETKRPIDTVISQQAFYSDESVSAMEKQYLRNSNLTPQQKIDELHHGFTGLDLEEQWMYPSRSDHSNCHNIQTNDTAKTTFQEYPLIKNCFTPQTGLSDIMKESGVDIYHYGRDRICTKGLEAPLQQKRAEMFLSQFNRYNENVDYCRYPEYVHPNKAKLNKCSNFSVQDSKKLANGTPETPTVEADTYTKLFQVKPANQKKMEETIPDQQNFTFPKTTPHLTEKQFAKEAVFTADFGLTSEYGLKPHTACPANDFANVTEKQQFAKPDPPHSEYFKSVNLLSNSATSSGGINLNRPTWMNVQTKNNTPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTPNSNLFQKYCQENPSAFSSFDFSYSGAERIQSVNHIEGLTKPGEENLFKLVTDKKIKQPNGFCDNYSAQKYGIIENVNKHNFQAKPQSGHYDPEEGPKHLDGLSQNTYQDLLESQGHSNSHRTRGGDNSRVNRTQVSCFSNNYMMGDLRHNQCFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLLSYDDLSHLYPYFNMMYGDNSFSGLMPTFGFQRPIKTRSGPASELHIRLEECCEQWRALEKERKKTELALAKNYPGKKVSSTNNTPVPRLTSNPSRVDRLIVDELRELARVVTLLGKMERLRSSLLHASISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALASAIKEMCVATRKTRTALWCALQMTLPKTASTADVVKPLQDTVNCEDKVHESINSSNPMNQRGETNKH"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RUB1#A2RUB1-1", 
            "isoform_ac": "A2RUB1-1", 
            "locus": {
                "end_pos": 44666410, 
                "start_pos": 44669535, 
                "chromosome": "17", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000409464", 
                        "id": "ENST00000409464", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000386586", 
                        "id": "ENSP00000386586", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2RUB1-1|MEIOC_HUMAN Isoform 1 of Meiosis-specific coiled-coil domain-containing protein MEIOC  OS=Homo sapiens OX=9606 GN=MEIOC PE=2 SV=3 CANONICAL=A2RUB1-4", 
                "length": 659, 
                "sequence": "MNTSRFADHHDLLTETKRPIDTVISQQAFYSDESVSAMEKQYLRNSNLTPQQKIDELHHGFTGLDLEEQWMYPSRSDHSNCHNIQTNDTAKTTFQEYPLIKNCFTPQTGLSDIMKESGVDIYHYGRDRICTKGLEAPLQQKRAEMFLSQFNRYNENVDYCRYPEYVHPNKAKLNKCSNFSVQDSKKLANGTPETPTVEADTYTKLFQVKPANQKKMEETIPDQQNFTFPKTTPHLTEKQFAKEAVFTADFGLTSEYGLKPHTACPANDFANVTEKQQFAKPDPPHSEYFKSVNLLSNSATSSGGINLNRPTWMNVQTKNNTPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTPNSNLFQKYCQENPSAFSSFDFSYSGAERIQSVNHIEGLTKPGEENLFKLVTDKKIKQPNGFCDNYSAQKYGIIENVNKHNFQAKPQSGHYDPEEGPKHLDGLSQNTYQDLLESQGHSNSHRTRGGDNSRVNRTQVSCFSNNYMMGDLRHNQCFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLLSYDDLSHLYPYFNMMYGDNSFSGLMPTFGFQRPIKTRSGPASELHIRLEECCEQWRALEKERKKTELALAKNYPGKKVSSTNNTPVPRLTSNPSRVDRLIVDELRELARVSCKNR"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RUB1#A2RUB1-2", 
            "isoform_ac": "A2RUB1-2", 
            "locus": {
                "end_pos": 0, 
                "start_pos": 0, 
                "chromosome": "N/A", 
                "evidence": []
            }, 
            "sequence": {
                "header": "sp|A2RUB1-2|MEIOC_HUMAN Isoform 2 of Meiosis-specific coiled-coil domain-containing protein MEIOC  OS=Homo sapiens OX=9606 GN=MEIOC PE=2 SV=3 CANONICAL=A2RUB1-4", 
                "length": 786, 
                "sequence": "MNTSRFADHHDLLTETKRPIDTVISQQAFYSDESVSAMEKQYLRNSNLTPQQKIDELHHGFTGLDLEEQWMYPSRSDHSNCHNIQTNDTAKTTFQEYPLIKNCFTPQTGLSDIMKESGVDIYHYGRDRICTKGLEAPLQQKRAEMFLSQFNRYNENVDYCRYPEYVHPNKAKLNKCSNFSVQDSKKLANGTPETPTVEADTYTKLFQVKPANQKKMEETIPDQQNFTFPKTTPHLTEKQFAKEAVFTADFGLTSEYGLKPHTACPANDFANVTEKQQFAKPDPPHSEYFKSVNLLSNSATSSGGINLNRPTWMNVQTKNNTPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTPNSNLFQKYCQENPSAFSSFDFSYSGAERIQSVNHIEGLTKPGEENLFKLVTDKKIKQPNGFCDNYSAQKYGIIENVNKHNFQAKPQSGHYDPEEGPKHLDGLSQNTYQDLLESQGHSNSHRTRGGDNSRVNRTQVSCFSNNYMMGDLRHNQCFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLLSYDDLSHLYPYFNMMYGDNSFSGLMPTFGFQRPIKTRSGPASELHIRLEECCEQWRALEKERKKTELALAKNYPGKKVSSTNNTPVPRLTSNPSRVDRLIVDELRELARVVTLLGKMERLRSSLLHASISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALASAIKEMCVATRKTRTALWCALQMTLPKTASTADVVKPLQDTVNCEDKVHESINSSNPMNQRGETNKH"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:284071", 
            "resource": "KEGG Pathway", 
            "id": "hsa:284071", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RUB1#function", 
            "annotation": "Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RUB1#function", 
                    "id": "A2RUB1", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138552.2", 
            "annotation": "Meioc is expressed in germ cells during meiotic prophase I. MEIOC prevents meiotic transcript degradation and interacts with an RNA helicase that binds numerous meiotic mRNAs. Publication Status: Online-Only", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138552.2", 
                    "id": "NP_001138552.2", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "A2AG06-1", 
            "protein_name": "Meiosis-specific coiled-coil domain-containing protein MEIOC; Meiosis-specific with coiled-coil domain protein", 
            "sequence": {
                "length": 965, 
                "sequence": "MEVSGGDTCRPRHPQGLREGPEPKVAAAAAAFRGSANRCWNLSVDTSNRLSDVFNSMMLTGSAPFYDCYKSQNEDNVDLRQTCTPLSSSTEYASSIDSSLFYAPWSTYGDDIKQPPSSQISVKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFVDHHDLLTEPKRPVDTSISQQAFYSGESVSAVEKQYLHNSSLTPQQKIDELYHGYTGLDLEEQWLYLSRSDHSNCYNSQANDTVKATFQEYPFVKNCFTPQTGLSDIMKESGIDTYAYGREKICTKGLETPLQHKRAEIFLSQFNRYNENADYCRYPEYAHPNKAKLNKCSNFSVQDGKKLANGTPETPTVEADAYTKLFQVKPANQKKMEETIPDQQNFAFPKTTPHLTEKQFAKEAAFTADFGLKSEYGLKPHTACPTNNDFANVSEKQQFAKPDPLNSEYFKSVNLFSNSATSSGGISLNRPTWMNVQTKNNLPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTSNSNLFQKYCQENPSAFSSFDFSYNGAERIQSVNHMEGLTKTGEDNLFESVTEKKIKQPNGFCDSYSASQYGIIENVNKHNFQAKPQSGHYDPEDIPKHFDGLPQNTYQDLLESQGHFNSHRQGSGDNNINSRVNRTQASCFSNNYMMGDLRHNQGFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLFSYDDLSHLYPYFNDMMYGDNSFSGFVPTFGFQRPIKTRSGPASELHIRLEECYEQWRALEKERKKTELALAKNYPGKKVSSTNNTPIPRLTSNPSRVDRLIVDELREQARVVTLLGKMERLRSSPLHANISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALATAIKEMCVATRKARTTLWCALQMTLPKTASTAGQADMEKAFQDLVNCEEKVHESINSSNPMNQRGETSKH"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/19559", 
                    "id": "19559", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/D4A1P7/", 
                    "id": "D4A1P7", 
                    "database": "OMA"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "D4A1P7-1", 
            "protein_name": "Meiosis-specific with coiled-coil domain", 
            "sequence": {
                "length": 940, 
                "sequence": "MEPKVAFRGSANRCWNLSVDTSSRLSDVFNSMMLTGSTSFYDCYKSQNEDNVDLRQTCTPLSSSAEYASSIDSSLFYAPWSTYGDDIKQPSSSQISVKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFVDHHDLLTENKRPIDTSISQQAFYSGESVSAVEKQYLHNSTLTPQQKIDELYHGYTGLDLEEQWLYLSRSDHSNCYNIQTNDTVKATFQEYPFIKNCFTPQTGLSDIMKESGIDTYAYGREKICAKGLETPLQHKRAEIFLSQFNRFNENADYCRYPEYAHPNKTKLNKCSNFSVQDGKKLANGTPETPTVEADAYTKLFQVKPANQKKMEETIPDQQNFAFPKTTPHLTEKQFAKEAAFTADFGLKSEYGLKPHTACPANNDFANVTEKQQFAKPDTLNSEYFKSVNLFSNSATSSGGISLNRPTWMNVQTKNNLPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTSNSNLFQKYCQENPSAFSSFDFSYNGAERIQSVNHMEGLTKTGEDNLFESVTEKKIKQPNGFCDGCSASQYGVIENVNKHNFQAKPQSGHYDPEDIPKHFDGLPQNTYQDLLESQGHFNSHRQGSGDNNINSRVNRTQASCFSNNYMMGDLRHNQGFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLFSYDDLSHLYPYFNDMMYGDNSFSGFVPTFGFQRPIKTRSGPASELHIRLEECYEQWRALEKERKKTELALAKNYPGKKVSSTNNTPIPRLTSNPSRVDRLIVDELREQARVVTLLGKMERLRSSPLHANISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALATAIKEMCVATRKARTTLWCALQMTLPKTASTAGQADMEKAFQDLVNCEDKVHESINSSNPMNQRGETSKH"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/19559", 
                    "id": "19559", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A2AG06/", 
                    "id": "A2AG06", 
                    "database": "OMA"
                }
            ], 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138552.2", 
        "ac": "NP_001138552.2", 
        "name": "meiosis-specific coiled-coil domain-containing protein MEIOC", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007144", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "female meiosis I", 
                        "id": "GO:0007144"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mRNA stabilization", 
                        "id": "GO:0048255"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "male meiosis I", 
                        "id": "GO:0007141"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051310", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "metaphase plate congression", 
                        "id": "GO:0051310"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "spermatid development", 
                        "id": "GO:0007286"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "double-strand break repair", 
                        "id": "GO:0006302"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007130", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "synaptonemal complex assembly", 
                        "id": "GO:0007130"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048599", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "oocyte development", 
                        "id": "GO:0048599"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070192", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "chromosome organization involved in meiotic cell cycle", 
                        "id": "GO:0070192"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051729", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUB1", 
                                "id": "A2RUB1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "germline cell cycle switching, mitotic to meiotic cell cycle", 
                        "id": "GO:0051729"
                    }
                ], 
                "total": 10, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 170, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 168
        }, 
        {
            "end_pos": 940, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 938
        }, 
        {
            "end_pos": 660, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 658
        }, 
        {
            "end_pos": 439, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 437
        }, 
        {
            "end_pos": 514, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 512
        }, 
        {
            "end_pos": 357, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 355
        }, 
        {
            "end_pos": 393, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 391
        }, 
        {
            "end_pos": 215, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 213
        }, 
        {
            "end_pos": 487, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 485
        }, 
        {
            "end_pos": 865, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 863
        }, 
        {
            "end_pos": 346, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 344
        }, 
        {
            "end_pos": 593, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 591
        }, 
        {
            "end_pos": 526, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 524
        }, 
        {
            "end_pos": 255, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 253
        }, 
        {
            "end_pos": 794, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 792
        }
    ], 
    "crossref": [
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33861", 
            "id": "PTHR33861", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027963", 
            "id": "IPR027963", 
            "database": "InterPro"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
            "id": "ENSG00000180336", 
            "database": "Bgee"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF15189", 
            "id": "PF15189", 
            "database": "Pfam"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/GANRCWN/", 
            "id": "GANRCWN", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:284071", 
            "id": "hsa:284071", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/284071", 
            "id": "284071", 
            "database": "GeneID"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2RUB1", 
            "id": "PR_A2RUB1", 
            "database": "PRO"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A2RUB1", 
            "id": "A2RUB1", 
            "database": "PHAROS"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A2RUB1*", 
            "id": "A2RUB1", 
            "database": "IntAct"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=26670", 
            "id": "26670", 
            "database": "HGNC"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A2RUB1", 
            "id": "NX_A2RUB1", 
            "database": "neXtProt"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=MEIOC", 
            "id": "MEIOC", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138552.2", 
            "id": "NP_001138552.2", 
            "database": "RefSeq"
        }
    ], 
    "expression_disease": [
        {
            "name": "Urinary bladder cancer [DO disease name]", 
            "trend": "Up", 
            "icd10": "C67", 
            "disease": {
                "doid": "11054", 
                "url": "http://disease-ontology.org/term/DOID:11054", 
                "icd10": "", 
                "name": "Urinary bladder cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:11054", 
            "significant": "No"
        }, 
        {
            "name": "Esophageal cancer [DO disease name]", 
            "trend": "Up", 
            "icd10": "C15.3", 
            "disease": {
                "doid": "5041", 
                "url": "http://disease-ontology.org/term/DOID:5041", 
                "icd10": "", 
                "name": "Esophageal cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:5041", 
            "significant": "No"
        }, 
        {
            "name": "Lung squamous cell carcinoma [DO disease name]", 
            "trend": "Up", 
            "disease": {
                "doid": "3907", 
                "url": "http://disease-ontology.org/term/DOID:3907", 
                "icd10": "", 
                "name": "Lung squamous cell carcinoma"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3907", 
            "significant": "Yes"
        }, 
        {
            "name": "Thyroid gland cancer [DO disease name]", 
            "trend": "Down", 
            "icd10": "C73", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid gland cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:1781", 
            "significant": "No"
        }, 
        {
            "name": "Prostate cancer [DO disease name]", 
            "trend": "Up", 
            "icd10": "C61", 
            "disease": {
                "doid": "10283", 
                "url": "http://disease-ontology.org/term/DOID:10283", 
                "icd10": "", 
                "name": "Prostate cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:10283", 
            "significant": "No"
        }, 
        {
            "name": "Lung adenocarcinoma [DO disease name]", 
            "trend": "Up", 
            "disease": {
                "doid": "3910", 
                "url": "http://disease-ontology.org/term/DOID:3910", 
                "icd10": "", 
                "name": "Lung adenocarcinoma"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3910", 
            "significant": "No"
        }, 
        {
            "name": "Liver cancer [DO disease name]", 
            "trend": "Down", 
            "icd10": "C22.0", 
            "disease": {
                "doid": "3571", 
                "url": "http://disease-ontology.org/term/DOID:3571", 
                "icd10": "", 
                "name": "Liver cancer"
            }, 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUB1", 
                    "id": "A2RUB1", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3571", 
            "significant": "No"
        }
    ], 
    "glycosylation": [], 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 107559.0, 
        "chemical_mass": 107559.0
    }, 
    "expression_tissue": [
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001150", 
                "uberon": "0001150", 
                "name": "Body of pancreas"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001160", 
                "uberon": "0001160", 
                "name": "Fundus of stomach"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001161", 
                "uberon": "0001161", 
                "name": "Body of stomach"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002046", 
                "uberon": "0002046", 
                "name": "Thyroid gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002369", 
                "uberon": "0002369", 
                "name": "Adrenal gland"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002107", 
                "uberon": "0002107", 
                "name": "Liver"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002048", 
                "uberon": "0002048", 
                "name": "Lung"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000178", 
                "uberon": "0000178", 
                "name": "Blood"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001150", 
                "uberon": "0001150", 
                "name": "Body of pancreas"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002107", 
                "uberon": "0002107", 
                "name": "Liver"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000996", 
                "uberon": "0000996", 
                "name": "Vagina"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000180336", 
                    "id": "ENSG00000180336", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
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                    "id": "ENSG00000180336", 
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        {
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                    "id": "ENSG00000180336", 
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        {
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                "name": "Ovary"
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            "evidence": [
                {
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                    "id": "ENSG00000180336", 
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        {
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                "uberon": "0002367", 
                "name": "Prostate gland"
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                    "id": "ENSG00000180336", 
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        {
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                    "id": "ENSG00000180336", 
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    ], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RUB1", 
            "": "", 
            "name": "MEIOC; C17orf104", 
            "locus": {
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                "start_pos": 44656404, 
                "chromosome": "17", 
                "evidence": [
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                        "id": "ENSG00000180336", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}