{
    "uniprot_canonical_ac": "A2RST1-1", 
    "sequence": {
        "header": "tr|A2RST1-1|A2RST1_MOUSE Isoform 1 of Microsomal glutathione S-transferase 2, isoform CRA_c  OS=Mus musculus OX=10090 GN=Mgst2 PE=1 SV=1 CANONICAL=A2RST1-1", 
        "length": 147, 
        "sequence": "MAGDSSLLAAVSLLSACQQSYFAWRVGRARLKHKIAPPAVTGPLEFERIFRAQQNSLEFYPVFIVMLWMAGWYFNQVFAACLGLLYIYARHKYFWGYAEAAEKRITGFRLSLGILTLLPVLAVLGVASRFLNEYLDFHVAKKLRKPF"
    }, 
    "uniprot_id": "A2RST1_MOUSE", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "microsomal glutathione S-transferase 2 isoform 1"
            ], 
            "uniprotkb": [
                "Microsomal glutathione S-transferase 2, isoform CRA_c", 
                "Microsomal glutathione S-transferase 2"
            ]
        }, 
        "gene": {
            "refseq": [
                "Mgst2", 
                "GST2", 
                "MGST-II"
            ], 
            "uniprotkb": [
                "Mgst2", 
                "mCG_22172", 
                "GST2", 
                "MGST-II"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RST1", 
                    "id": "A2RST1", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "recommendedname": {
        "full": "Microsomal glutathione S-transferase 2, isoform CRA_c; Microsomal glutathione S-transferase 2."
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RST1#A0A0A6YWX7-1", 
            "isoform_ac": "A0A0A6YWX7-1", 
            "locus": {
                "end_pos": 51661249, 
                "start_pos": 51682470, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000159554", 
                        "id": "ENSMUST00000159554", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000141745", 
                        "id": "ENSMUSP00000141745", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0A6YWX7-1|A2RST1_MOUSE Computationally mapped isoform of Microsomal glutathione S-transferase 2, isoform CRA_c  OS=Mus musculus OX=10090 GN=Mgst2 PE=1 SV=1 CANONICAL=A2RST1-1", 
                "length": 82, 
                "sequence": "MAGDSSLLAAVSLLSACQQSYFAWRVGRARLKHKIAPPAVTGPLEFERIFRAQQNSLEFYPVFIVMLWMAGWYFNQGSPVSD"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RST1#A2RST1-1", 
            "isoform_ac": "A2RST1-1", 
            "locus": {
                "end_pos": 51661249, 
                "start_pos": 51682583, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000099106", 
                        "id": "ENSMUST00000099106", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000096705", 
                        "id": "ENSMUSP00000096705", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A2RST1-1|A2RST1_MOUSE Isoform 1 of Microsomal glutathione S-transferase 2, isoform CRA_c  OS=Mus musculus OX=10090 GN=Mgst2 PE=1 SV=1 CANONICAL=A2RST1-1", 
                "length": 147, 
                "sequence": "MAGDSSLLAAVSLLSACQQSYFAWRVGRARLKHKIAPPAVTGPLEFERIFRAQQNSLEFYPVFIVMLWMAGWYFNQVFAACLGLLYIYARHKYFWGYAEAAEKRITGFRLSLGILTLLPVLAVLGVASRFLNEYLDFHVAKKLRKPF"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RST1#E0CZ62-1", 
            "isoform_ac": "E0CZ62-1", 
            "locus": {
                "end_pos": 51661249, 
                "start_pos": 51681869, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000161590", 
                        "id": "ENSMUST00000161590", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000125670", 
                        "id": "ENSMUSP00000125670", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|E0CZ62-1|A2RST1_MOUSE Computationally mapped isoform of Microsomal glutathione S-transferase 2, isoform CRA_c  OS=Mus musculus OX=10090 GN=Mgst2 PE=1 SV=1 CANONICAL=A2RST1-1", 
                "length": 77, 
                "sequence": "MAGDSSLLAAVSLLSACQQSYFAWRVGRARLKHKIAPPAVTGPLEFERIFRAHFCSLSGSPVHIRPSQVFLGLCRSR"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-156590", 
            "resource": "Reactome", 
            "id": "R-MMU-156590", 
            "name": "Glutathione conjugation"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5423646", 
            "resource": "Reactome", 
            "id": "R-MMU-5423646", 
            "name": "Aflatoxin activation and detoxification"
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q99735-1", 
            "protein_name": "Microsomal glutathione S-transferase 2; Microsomal GST-2; 2.5.1.18; Microsomal GST-II.", 
            "sequence": {
                "length": 147, 
                "sequence": "MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNCVEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILALLTLLGALGIANSFLDEYLDLNIAKKLRRQF"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/833769/", 
                    "id": "833769", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/1811", 
                    "id": "1811", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "A0A0G2JU12-1", 
            "protein_name": "Microsomal glutathione S-transferase 2.", 
            "sequence": {
                "length": 128, 
                "sequence": "GYFALQVGRVRLKYKIAPPAVTGSLEFERIFRAQQNSLEFYSVFIISLWMAGWYFNQVFATCLGLLYIYARHKYFWGYAEAAEKRIIGFRLSLGILALLTVLAVLGVASRFLDEYLDFHVAKKLKRPF"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/833769/", 
                    "id": "833769", 
                    "database": "OMA"
                }
            ], 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_778160.2", 
        "ac": "NP_778160.2", 
        "name": "microsomal glutathione S-transferase 2 isoform 1.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "glutathione transferase activity", 
                        "id": "GO:0004364"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004464", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "leukotriene-C4 synthase activity", 
                        "id": "GO:0004464"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "enzyme activator activity", 
                        "id": "GO:0008047"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "glutathione peroxidase activity", 
                        "id": "GO:0004602"
                    }
                ], 
                "total": 4, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nuclear envelope", 
                        "id": "GO:0005635"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "endoplasmic reticulum", 
                        "id": "GO:0005783"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "plasma membrane", 
                        "id": "GO:0005886"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "membrane", 
                        "id": "GO:0016020"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "intracellular membrane-bounded organelle", 
                        "id": "GO:0043231"
                    }
                ], 
                "total": 7, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006750", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "glutathione biosynthetic process", 
                        "id": "GO:0006750"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "lipid metabolic process", 
                        "id": "GO:0006629"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019370", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "leukotriene biosynthetic process", 
                        "id": "GO:0019370"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046466", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RST1", 
                                "id": "A2RST1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "membrane lipid catabolic process", 
                        "id": "GO:0046466"
                    }
                ], 
                "total": 4, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_778160.2", 
            "id": "NP_778160.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-156590", 
            "id": "R-MMU-156590", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5423646", 
            "id": "R-MMU-5423646", 
            "database": "Reactome"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000074604", 
            "id": "ENSMUSG00000074604", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/HKYFWGY/", 
            "id": "HKYFWGY", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001129", 
            "id": "IPR001129", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001446", 
            "id": "IPR001446", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023352", 
            "id": "IPR023352", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF01124", 
            "id": "PF01124", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/211666", 
            "id": "211666", 
            "database": "GeneID"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:2448481", 
            "id": "2448481", 
            "database": "MGI"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A2RST1", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 16786.0, 
        "chemical_mass": 16786.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RST1", 
            "name": "Mgst2; mCG_22172; GST2; MGST-II.", 
            "locus": {
                "end_pos": 51682677, 
                "start_pos": 51660360, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000074604", 
                        "id": "ENSMUSG00000074604", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}