{
    "uniprot_canonical_ac": "A2AVQ5-1", 
    "sequence": {
        "header": "sp|A2AVQ5-1|LEXM_MOUSE Isoform 1 of Lymphocyte expansion molecule  OS=Mus musculus OX=10090 GN=Lexm PE=2 SV=1 CANONICAL=A2AVQ5-1", 
        "length": 414, 
        "sequence": "MRPRTHGAPPRNIMSTIPKWFKGAPFGVQSHRFDVSAVYPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKDTCFSKKFLEQKLGSGWSQAHEATRLTQLPHFHYQAIKKEKEQQVHKRGPGSYNIKDFITELQKKPQSKRGLLSSGETRFRGFIGNYYPGPGNYGEKGNPYTQLEEKAWNRSHSDGLMCRVSNKPPLFHQGSGLGPGTYTIKSDLETFVKKSTGNRGPYDIFSGERSSPLPYGHYSVQKMKPKELTDYKSFLDEMNSQHKKKQGVFSKYPRDPKHPTERIFWTTLSQCPKNMDIAGPGSWLPHETEQKHVNRPPFLLASKRCGLKAYQMILGTWNPVGVGRYLNTTLMESIDRRQRYRSLYMSEPKRYLQDLTRDRLMQKRITPITKGKCRPTVDYNSDPTP"
    }, 
    "uniprot_id": "LEXM_MOUSE", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "lymphocyte expansion molecule"
            ], 
            "uniprotkb": [
                "Lymphocyte expansion molecule"
            ]
        }, 
        "gene": {
            "refseq": [
                "Lexm"
            ], 
            "uniprotkb": [
                "Lexm", 
                "Lem"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AVQ5", 
                    "id": "A2AVQ5", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "recommendedname": {
        "full": "Lymphocyte expansion molecule."
    }, 
    "publication": [
        {
            "title": "T cell metabolism. The protein LEM promotes CD8+ T cell immunity through effects on mitochondrial respiration.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/25883318", 
            "journal": "Science", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AVQ5", 
                    "id": "A2AVQ5", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Wang L., Ichimura T., Haas R., Richter K., Oxenius A., Abdi R., Ashton-Rickardt P.G., Choi O., Crouse J., Heathcote D., Lovo E., Mauro C., Okoye I., Pallmer K., Rutschmann S.", 
            "date": "2015", 
            "pmid": "25883318"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AVQ5#A2AVQ5-1", 
            "isoform_ac": "A2AVQ5-1", 
            "locus": {
                "end_pos": 106591618, 
                "start_pos": 106617219, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000067387", 
                        "id": "ENSMUST00000067387", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000066732", 
                        "id": "ENSMUSP00000066732", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2AVQ5-1|LEXM_MOUSE Isoform 1 of Lymphocyte expansion molecule  OS=Mus musculus OX=10090 GN=Lexm PE=2 SV=1 CANONICAL=A2AVQ5-1", 
                "length": 414, 
                "sequence": "MRPRTHGAPPRNIMSTIPKWFKGAPFGVQSHRFDVSAVYPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKDTCFSKKFLEQKLGSGWSQAHEATRLTQLPHFHYQAIKKEKEQQVHKRGPGSYNIKDFITELQKKPQSKRGLLSSGETRFRGFIGNYYPGPGNYGEKGNPYTQLEEKAWNRSHSDGLMCRVSNKPPLFHQGSGLGPGTYTIKSDLETFVKKSTGNRGPYDIFSGERSSPLPYGHYSVQKMKPKELTDYKSFLDEMNSQHKKKQGVFSKYPRDPKHPTERIFWTTLSQCPKNMDIAGPGSWLPHETEQKHVNRPPFLLASKRCGLKAYQMILGTWNPVGVGRYLNTTLMESIDRRQRYRSLYMSEPKRYLQDLTRDRLMQKRITPITKGKCRPTVDYNSDPTP"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AVQ5#F6X5R4-1", 
            "isoform_ac": "F6X5R4-1", 
            "locus": {
                "end_pos": 106591618, 
                "start_pos": 106607395, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000126324", 
                        "id": "ENSMUST00000126324", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000118338", 
                        "id": "ENSMUSP00000118338", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|F6X5R4-1|LEXM_MOUSE Computationally mapped isoform of Lymphocyte expansion molecule  OS=Mus musculus OX=10090 GN=Lexm PE=2 SV=1 CANONICAL=A2AVQ5-1", 
                "length": 59, 
                "sequence": "NTTLMESIDRRQRYRSLYMSEPKRYLQDLTRDRLMQKRITPITKGKCRPTVDYNSDPTP"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:242602", 
            "resource": "KEGG Pathway", 
            "id": "mmu:242602", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q3ZCV2-1", 
            "protein_name": "Lymphocyte expansion molecule.", 
            "sequence": {
                "length": 418, 
                "sequence": "MRESQDAAGAHGWNRVGSTATKWFTGAPFGVQSHRFDISAVYPNWKKFSTFTEAPYSTRYSTQVSHIGPGTYSSKETCFSKKKLMKEVDTGWAKAQEATRLTQLPHFQYQAIMKEKRLKEQKLGPGSYNLKDFLEQLREKPCSTRGLLSSGEVRFRGLTGNYYPGPGNYGEKGNPYTKLEENAWNRSHSEGLMCRMSNKPHPRPHQGSGLGPGTYFFKSDLETYVARSVGTRGPYDTFSGDRSKPLPYGHYSMQKKKPRELMNFKSFVEELNSHHNKKHGVFSKLPRNPKTPTERIYWANLSQCPRTLATSGPSFWLPQEKKCKPVNQPPFLLTSKGSGAKACQMIMGSWNPVGVGRYLNTWLMETKDRRQRYRSLFLSGSKRYLSDLARDMLMQERITPFTKGKCPPTVDYNSDPTP"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/17630", 
                    "id": "17630", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/816072/", 
                    "id": "816072", 
                    "database": "OMA"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "B1H283-1", 
            "protein_name": "Lymphocyte expansion molecule.", 
            "sequence": {
                "length": 402, 
                "sequence": "MSTIRKWFKGAPFGVQSHRFDVSAVHPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKETCFSKKFLEQKLGAGWARAQEASRLTQLPHFHFQAIKKEREQQANKRGPGSYNIKDFLTELQKKPQSKRGLLSSGETRFRGLIGNYYPGPGNYGEKGNPYTQLEKNSWNRSHSDGLMCRLSSKPPPLSHQGSGLGPGTYTIKSDIETFVEKSTGTRGPYDIFSGERSSPVPYGHYSVQKKKPRELTSFKSFVDELNAPHKKKQGGFSKYPRDPKHPTERIYWTTLSQCPKDVNVAGPGSWLPHETEQKHVNRPPFLLASKRSGLKACQMLLGTWNPVGVGRYLNTTLMEKIDRRQRYRSLFMSEPKRYLHDLNRDKLLQERITPFTKGKCRPTVDYNSDPTP"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/17630", 
                    "id": "17630", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/816072/", 
                    "id": "816072", 
                    "database": "OMA"
                }
            ], 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_899005.2", 
        "ac": "NP_899005.2", 
        "name": "lymphocyte expansion molecule.", 
        "summary": ""
    }, 
    "go_annotation": {}, 
    "site_annotation": [
        {
            "end_pos": 184, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 182
        }, 
        {
            "end_pos": 358, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 356
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_899005.2", 
            "id": "NP_899005.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:242602", 
            "id": "mmu:242602", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000054362", 
            "id": "ENSMUSG00000054362", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/PFTKGKC/", 
            "id": "PFTKGKC", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033557", 
            "id": "IPR033557", 
            "database": "InterPro"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34914", 
            "id": "PTHR34914", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2AVQ5", 
            "id": "PR_A2AVQ5", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/242602", 
            "id": "242602", 
            "database": "GeneID"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:2681853", 
            "id": "2681853", 
            "database": "MGI"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A2AVQ5", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 47584.0, 
        "chemical_mass": 47584.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AVQ5", 
            "name": "Lexm; Lem.", 
            "locus": {
                "end_pos": 106590909, 
                "start_pos": 106617241, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000054362", 
                        "id": "ENSMUSG00000054362", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}