{ "uniprot_canonical_ac": "A2AV25-1", "sequence": { "header": "sp|A2AV25-1|FBCD1_MOUSE Isoform 1 of Fibrinogen C domain-containing protein 1 OS=Mus musculus OX=10090 GN=Fibcd1 PE=2 SV=1 CANONICAL=A2AV25-1", "length": 459, "sequence": "MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLAVAVTGVVLFLNHTHTPGTAPPPIVSTGTAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRALSEHQAQPRLDGAPELLDALADQLPRLLTRASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR" }, "uniprot_id": "FBCD1_MOUSE", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "fibrinogen C domain-containing protein 1" ], "uniprotkb": [ "Fibrinogen C domain-containing protein 1" ] }, "gene": { "refseq": [ "Fibcd1", "AI448887" ], "uniprotkb": [ "Fibcd1", "AI448887" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AV25", "id": "A2AV25", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "recommendedname": { "full": "Fibrinogen C domain-containing protein 1." }, "publication": [], "glycosylation": [ { "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AV25#PTM_processing", "id": "A2AV25", "database": "UniProtKB" } ], "relation": "attached", "position": 338, "glytoucan_ac": "", "type": "N-linked" } ], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2AV25#A2AV25-1", "isoform_ac": "A2AV25-1", "locus": { "end_pos": 31816441, "start_pos": 31845782, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000028188", "id": "ENSMUST00000028188", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000028188", "id": "ENSMUSP00000028188", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AV25-1|FBCD1_MOUSE Isoform 1 of Fibrinogen C domain-containing protein 1 OS=Mus musculus OX=10090 GN=Fibcd1 PE=2 SV=1 CANONICAL=A2AV25-1", "length": 459, "sequence": "MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLAVAVTGVVLFLNHTHTPGTAPPPIVSTGTAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRALSEHQAQPRLDGAPELLDALADQLPRLLTRASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR" } }, { "url": "https://www.uniprot.org/uniprot/A2AV25#A2AV25-2", "isoform_ac": "A2AV25-2", "locus": { "end_pos": 0, "start_pos": 0, "chromosome": "N/A", "evidence": [] }, "sequence": { "header": "sp|A2AV25-2|FBCD1_MOUSE Isoform 2 of Fibrinogen C domain-containing protein 1 OS=Mus musculus OX=10090 GN=Fibcd1 PE=2 SV=1 CANONICAL=A2AV25-1", "length": 269, "sequence": "MAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:98970", "resource": "KEGG Pathway", "id": "mmu:98970", "name": "" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A2AV25#function", "annotation": "Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AV25#function", "id": "A2AV25", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q8N539-1", "protein_name": "Fibrinogen C domain-containing protein 1.", "sequence": { "length": 461, "sequence": "MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALAVLLAVAVTGAVLFLNHAHAPGTAPPPVVSTGAASANSALVTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/122246", "id": "122246", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "D4ADA1-1", "protein_name": "Fibrinogen C domain containing 1 (Predicted); Fibrinogen C domain-containing 1-like 1.", "sequence": { "length": 459, "sequence": "MVHERWKTVGGASQLEDRPRDKPQRAGCSYILCTVLLSLAVLLAVAVTGAVLFLNHAHAPGTAPPPIVSTGAAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRTLSEHQAQPRLDGAPELLDALADQLPRLLARASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGPHASYADGVEWSSWTGWQYSLKFSEMKIRPLREDR" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/268753/", "id": "268753", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/122246", "id": "122246", "database": "MGI" } ], "organism": "Rattus norvegicus", "tax_id": 10116 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849218.2", "ac": "NP_849218.2", "name": "fibrinogen C domain-containing protein 1.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AV25", "id": "A2AV25", "database": "UniProtKB" } ], "name": "metal ion binding", "id": "GO:0046872" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AV25", "id": "A2AV25", "database": "UniProtKB" } ], "name": "chitin binding", "id": "GO:0008061" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AV25", "id": "A2AV25", "database": "UniProtKB" } ], "name": "membrane", "id": "GO:0016020" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AV25", "id": "A2AV25", "database": "UniProtKB" } ], "name": "integral component of membrane", "id": "GO:0016021" } ], "total": 2, "name": "Cellular Component" } ] }, "site_annotation": [ { "end_pos": 57, "annotation": "n_glycosylation_sequon", "start_pos": 55 }, { "end_pos": 237, "annotation": "n_glycosylation_sequon", "start_pos": 235 }, { "end_pos": 340, "annotation": "n_glycosylation_sequon", "start_pos": 338 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849218.2", "id": "NP_849218.2", "database": "RefSeq" }, { "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:98970", "id": "mmu:98970", "database": "KEGG Pathway" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000026841", "id": "ENSMUSG00000026841", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/CSYVLCT/", "id": "CSYVLCT", "database": "OMA" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "id": "cd00087", "database": "CDD" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "id": "IPR002181", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR014715", "id": "IPR014715", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "id": "IPR014716", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR020837", "id": "IPR020837", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "id": "IPR036056", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00147", "id": "PF00147", "database": "Pfam" }, { "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2AV25", "id": "PR_A2AV25", "database": "PRO" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/98970", "id": "98970", "database": "GeneID" }, { "url": "http://www.informatics.jax.org/marker/MGI:2138953", "id": "2138953", "database": "MGI" } ], "expression_disease": [], "uniprot_ac": "A2AV25", "disease": [], "mass": { "monoisotopic_mass": 50602.0, "chemical_mass": 50602.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2AV25", "name": "Fibcd1; AI448887.", "locus": { "end_pos": 31813290, "start_pos": 31846005, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000026841", "id": "ENSMUSG00000026841", "database": "Ensembl Gene" } ] } } ] }