{
    "uniprot_canonical_ac": "A2AQ07-1", 
    "sequence": {
        "header": "sp|A2AQ07-1|TBB1_MOUSE Isoform 1 of Tubulin beta-1 chain  OS=Mus musculus OX=10090 GN=Tubb1 PE=1 SV=1 CANONICAL=A2AQ07-1", 
        "length": 451, 
        "sequence": "MREIVHIQIGQCGNQIGAKFWEVIGEEHGIDCAGSYCGTSALQLERISVYYNEAYGKKYVPRAVLVDLEPGTMDSIRSSRLGVLFQPDSFVHGNSGAGNNWAKGHYTEGAELIENVMDVVRRESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRILNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENTDACFCIDNEALYDICFRTLRLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNIMAACDPRRGRYLTVACIFRGKMSTKEVDQQLLSIQTRNSNCFVEWIPNNVKVAVCDIPPRGLNMAATFLGNNTAIQELFTRVSEHFSAMFRRRAFVHWYTSEGMDISEFGEAESDIHDLVSEYQQFQDVRAGLEDSEEDVEEAEVEAEDKDH"
    }, 
    "uniprot_id": "TBB1_MOUSE", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "tubulin beta-1 chain"
            ], 
            "uniprotkb": [
                "Tubulin beta-1 chain"
            ]
        }, 
        "gene": {
            "refseq": [
                "Tubb1", 
                "2810484G07Rik", 
                "M(beta)1"
            ], 
            "uniprotkb": [
                "Tubb1", 
                "2810484G07Rik", 
                "M(beta)1"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                    "id": "A2AQ07", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "recommendedname": {
        "full": "Tubulin beta-1 chain."
    }, 
    "publication": [
        {
            "title": "TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/30446499", 
            "journal": "EMBO molecular medicine", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
                    "id": "NP_001074440.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Stoupa A, Adam F, Kariyawasam D, Strassel C, Gawade S, Szinnai G, Kauskot A, Lasne D, Janke C, Natarajan K, Schmitt A, Bole-Feysot C, Nitschke P, Leger J, Jabot-Hanin F, Tores F, Michel A, Munnich A, Besmond C, Scharfmann R, Lanza F, Borgel D, Polak M, Carre A", 
            "date": "2018", 
            "pmid": "30446499"
        }, 
        {
            "title": "Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/30110642", 
            "journal": "Cell reports", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
                    "id": "NP_001074440.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Latremoliere A, Cheng L, DeLisle M, Wu C, Chew S, Hutchinson EB, Sheridan A, Alexandre C, Latremoliere F, Sheu SH, Golidy S, Omura T, Huebner EA, Fan Y, Whitman MC, Nguyen E, Hermawan C, Pierpaoli C, Tischfield MA, Woolf CJ, Engle EC", 
            "date": "2018", 
            "pmid": "30110642"
        }, 
        {
            "title": "KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/24960163", 
            "journal": "The Journal of clinical investigation", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
                    "id": "NP_001074440.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Garg A, O'Rourke J, Long C, Doering J, Ravenscroft G, Bezprozvannaya S, Nelson BR, Beetz N, Li L, Chen S, Laing NG, Grange RW, Bassel-Duby R, Olson EN", 
            "date": "2014", 
            "pmid": "24960163"
        }, 
        {
            "title": "Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/19524510", 
            "journal": "Cell", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                    "id": "A2AQ07", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Van Dorsselaer A., Strub J.-M., Thomas D., Gaertig J., Wloga D., Janke C., Rogowski K., van Dijk J., Bre M.-H., Juge F., Levilliers N.", 
            "date": "2009", 
            "pmid": "19524510"
        }, 
        {
            "title": "RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/18347012", 
            "journal": "J. Biol. Chem.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                    "id": "A2AQ07", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Shivdasani R.A., Italiano J.E. Jr., Korpal M., Dose M., Meyer I., Schulze H.", 
            "date": "2008", 
            "pmid": "18347012"
        }, 
        {
            "title": "Large-scale phosphorylation analysis of mouse liver.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/17242355", 
            "journal": "Proc. Natl. Acad. Sci. U.S.A.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                    "id": "A2AQ07", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Beausoleil S.A., Gerber S.A., Gygi S.P., Villen J.", 
            "date": "2007", 
            "pmid": "17242355"
        }, 
        {
            "title": "Tubulin polyglutamylase enzymes are members of the TTL domain protein family.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/15890843", 
            "journal": "Science", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                    "id": "A2AQ07", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "van Dorsselaer A., Strub J.-M., Gaertig J., Wloga D., Boucher D., Janke C., Regnard C., Kajava A.V., Rogowski K., van Dijk J., Edde B., Suryavanshi S., Temurak N.", 
            "date": "2005", 
            "pmid": "15890843"
        }, 
        {
            "title": "A ubiquitous beta-tubulin disrupts microtubule assembly and inhibits cell proliferation.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/15121885", 
            "journal": "Molecular biology of the cell", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
                    "id": "NP_001074440.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Bhattacharya R, Cabral F", 
            "date": "2004", 
            "pmid": "15121885"
        }, 
        {
            "title": "Mechanisms and implications of platelet discoid shape.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/12586623", 
            "journal": "Blood", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
                    "id": "NP_001074440.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Italiano JE Jr, Bergmeier W, Tiwari S, Falet H, Hartwig JH, Hoffmeister KM, Andre P, Wagner DD, Shivdasani RA", 
            "date": "2003", 
            "pmid": "12586623"
        }, 
        {
            "title": "A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/11369202", 
            "journal": "Current biology : CB", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
                    "id": "NP_001074440.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Schwer HD, Lecine P, Tiwari S, Italiano JE Jr, Hartwig JH, Shivdasani RA", 
            "date": "2001", 
            "pmid": "11369202"
        }, 
        {
            "title": "Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/10942379", 
            "journal": "Blood", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
                    "id": "NP_001074440.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Lecine P, Italiano JE Jr, Kim SW, Villeval JL, Shivdasani RA", 
            "date": "2000", 
            "pmid": "10942379"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AQ07#A2AQ07-1", 
            "isoform_ac": "A2AQ07-1", 
            "locus": {
                "end_pos": 174450745, 
                "start_pos": 174457879, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000016399", 
                        "id": "ENSMUST00000016399", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000016399", 
                        "id": "ENSMUSP00000016399", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2AQ07-1|TBB1_MOUSE Isoform 1 of Tubulin beta-1 chain  OS=Mus musculus OX=10090 GN=Tubb1 PE=1 SV=1 CANONICAL=A2AQ07-1", 
                "length": 451, 
                "sequence": "MREIVHIQIGQCGNQIGAKFWEVIGEEHGIDCAGSYCGTSALQLERISVYYNEAYGKKYVPRAVLVDLEPGTMDSIRSSRLGVLFQPDSFVHGNSGAGNNWAKGHYTEGAELIENVMDVVRRESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRILNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENTDACFCIDNEALYDICFRTLRLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNIMAACDPRRGRYLTVACIFRGKMSTKEVDQQLLSIQTRNSNCFVEWIPNNVKVAVCDIPPRGLNMAATFLGNNTAIQELFTRVSEHFSAMFRRRAFVHWYTSEGMDISEFGEAESDIHDLVSEYQQFQDVRAGLEDSEEDVEEAEVEAEDKDH"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:545486", 
            "resource": "KEGG Pathway", 
            "id": "mmu:545486", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2500257", 
            "resource": "Reactome", 
            "id": "R-MMU-2500257", 
            "name": "Resolution of Sister Chromatid Cohesion"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-190840", 
            "resource": "Reactome", 
            "id": "R-MMU-190840", 
            "name": "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2467813", 
            "resource": "Reactome", 
            "id": "R-MMU-2467813", 
            "name": "Separation of Sister Chromatids"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-68877", 
            "resource": "Reactome", 
            "id": "R-MMU-68877", 
            "name": "Mitotic Prometaphase"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-380320", 
            "resource": "Reactome", 
            "id": "R-MMU-380320", 
            "name": "Recruitment of NuMA to mitotic centrosomes"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-437239", 
            "resource": "Reactome", 
            "id": "R-MMU-437239", 
            "name": "Recycling pathway of L1"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5663220", 
            "resource": "Reactome", 
            "id": "R-MMU-5663220", 
            "name": "RHO GTPases Activate Formins"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6811436", 
            "resource": "Reactome", 
            "id": "R-MMU-6811436", 
            "name": "COPI-independent Golgi-to-ER retrograde traffic"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8852276", 
            "resource": "Reactome", 
            "id": "R-MMU-8852276", 
            "name": "The role of GTSE1 in G2/M progression after G2 checkpoint"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2132295", 
            "resource": "Reactome", 
            "id": "R-MMU-2132295", 
            "name": "MHC class II antigen presentation"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5610787", 
            "resource": "Reactome", 
            "id": "R-MMU-5610787", 
            "name": "Hedgehog 'off' state"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5617833", 
            "resource": "Reactome", 
            "id": "R-MMU-5617833", 
            "name": "Cilium Assembly"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8955332", 
            "resource": "Reactome", 
            "id": "R-MMU-8955332", 
            "name": "Carboxyterminal post-translational modifications of tubulin"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-983189", 
            "resource": "Reactome", 
            "id": "R-MMU-983189", 
            "name": "Kinesins"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3371497", 
            "resource": "Reactome", 
            "id": "R-MMU-3371497", 
            "name": "HSP90 chaperone cycle for steroid hormone receptors (SHR)"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5620924", 
            "resource": "Reactome", 
            "id": "R-MMU-5620924", 
            "name": "Intraflagellar transport"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5626467", 
            "resource": "Reactome", 
            "id": "R-MMU-5626467", 
            "name": "RHO GTPases activate IQGAPs"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6807878", 
            "resource": "Reactome", 
            "id": "R-MMU-6807878", 
            "name": "COPI-mediated anterograde transport"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6811434", 
            "resource": "Reactome", 
            "id": "R-MMU-6811434", 
            "name": "COPI-dependent Golgi-to-ER retrograde traffic"
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AQ07#function", 
            "annotation": "Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AQ07#function", 
                    "id": "A2AQ07", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
            "annotation": "In mice, Tubb1 knock-out disrupted microtubule integrity by preventing beta1-tubulin incorporation and impaired thyroid migration and thyroid hormone secretion.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
                    "id": "NP_001074440.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
            "annotation": "Findings highlight the essential requirements of the megakaryocyte/platelet-restricted beta1-tubulin isoform in platelet structure", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
                    "id": "NP_001074440.1", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9H4B7-1", 
            "protein_name": "Tubulin beta-1 chain.", 
            "sequence": {
                "length": 451, 
                "sequence": "MREIVHIQIGQCGNQIGAKFWEMIGEEHGIDLAGSDRGASALQLERISVYYNEAYGRKYVPRAVLVDLEPGTMDSIRSSKLGALFQPDSFVHGNSGAGNNWAKGHYTEGAELIENVLEVVRHESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRIMNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENADACFCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNTMAACDLRRGRYLTVACIFRGKMSTKEVDQQLLSVQTRNSSCFVEWIPNNVKVAVCDIPPRGLSMAATFIGNNTAIQEIFNRVSEHFSAMFKRKAFVHWYTSEGMDINEFGEAENNIHDLVSEYQQFQDAKAVLEEDEEVTEEAEMEPEDKGH"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/696205/", 
                    "id": "696205", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/69474", 
                    "id": "69474", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "M0R8B6-1", 
            "protein_name": "Tubulin beta chain.", 
            "sequence": {
                "length": 452, 
                "sequence": "MREIVHIQIGQCGNQIGAKFWEVIGEEHGIDCAGSYCGTSALQLERISVYYNEAYGKKYVPRAVLVDLEPGTMDSIRSSRLGILFQPDSFVHGNSGAGNNWAKGHYTEGAELIETVMDVVRRESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRILNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENTDACFCIDNEALYDICFRTLRLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNIMAACDPRRGRYLTVACIFRGKMSTKEVDQQLLSIQTRNSNCFVEWIPNNVKVAVCDIPPRGLNMAATFLGNNTAIQELFTRVSEHFSAMFRRRAFVHWYTSEGMDISEFGEAEADILDLVSEYQQFQDVRAGLEDIEEGGEEEAEMGAEDKNH"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/696205/", 
                    "id": "696205", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/69474", 
                    "id": "69474", 
                    "database": "MGI"
                }
            ], 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
        "ac": "NP_001074440.1", 
        "name": "tubulin beta-1 chain.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                                "id": "A2AQ07", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "structural constituent of cytoskeleton", 
                        "id": "GO:0005200"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                                "id": "A2AQ07", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "GTP binding", 
                        "id": "GO:0005525"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                                "id": "A2AQ07", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "GTPase activity", 
                        "id": "GO:0003924"
                    }
                ], 
                "total": 3, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                                "id": "A2AQ07", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "microtubule", 
                        "id": "GO:0005874"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                                "id": "A2AQ07", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                                "id": "A2AQ07", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mitotic cell cycle", 
                        "id": "GO:0000278"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                                "id": "A2AQ07", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "microtubule cytoskeleton organization", 
                        "id": "GO:0000226"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                                "id": "A2AQ07", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "spindle assembly", 
                        "id": "GO:0051225"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AQ07", 
                                "id": "A2AQ07", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "microtubule-based process", 
                        "id": "GO:0007017"
                    }
                ], 
                "total": 4, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 372, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 370
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074440.1", 
            "id": "NP_001074440.1", 
            "database": "RefSeq"
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        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2500257", 
            "id": "R-MMU-2500257", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-190840", 
            "id": "R-MMU-190840", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2467813", 
            "id": "R-MMU-2467813", 
            "database": "Reactome"
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        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-68877", 
            "id": "R-MMU-68877", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-380320", 
            "id": "R-MMU-380320", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-437239", 
            "id": "R-MMU-437239", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5663220", 
            "id": "R-MMU-5663220", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6811436", 
            "id": "R-MMU-6811436", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8852276", 
            "id": "R-MMU-8852276", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2132295", 
            "id": "R-MMU-2132295", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5610787", 
            "id": "R-MMU-5610787", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5617833", 
            "id": "R-MMU-5617833", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8955332", 
            "id": "R-MMU-8955332", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-983189", 
            "id": "R-MMU-983189", 
            "database": "Reactome"
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        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3371497", 
            "id": "R-MMU-3371497", 
            "database": "Reactome"
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        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5620924", 
            "id": "R-MMU-5620924", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5626467", 
            "id": "R-MMU-5626467", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6807878", 
            "id": "R-MMU-6807878", 
            "database": "Reactome"
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        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6811434", 
            "id": "R-MMU-6811434", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:545486", 
            "id": "mmu:545486", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000016255", 
            "id": "ENSMUSG00000016255", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/NTDACFC/", 
            "id": "NTDACFC", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017975", 
            "id": "IPR017975", 
            "database": "InterPro"
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008280", 
            "id": "IPR008280", 
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018316", 
            "id": "IPR018316", 
            "database": "InterPro"
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR037103", 
            "id": "IPR037103", 
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000217", 
            "id": "IPR000217", 
            "database": "InterPro"
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002453", 
            "id": "IPR002453", 
            "database": "InterPro"
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003008", 
            "id": "IPR003008", 
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013838", 
            "id": "IPR013838", 
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036525", 
            "id": "IPR036525", 
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        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023123", 
            "id": "IPR023123", 
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        }, 
        {
            "url": "http://pfam.xfam.org/family/PF03953", 
            "id": "PF03953", 
            "database": "Pfam"
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        {
            "url": "http://pfam.xfam.org/family/PF00091", 
            "id": "PF00091", 
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        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11588", 
            "id": "PTHR11588", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2AQ07", 
            "id": "PR_A2AQ07", 
            "database": "PRO"
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        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/545486", 
            "id": "545486", 
            "database": "GeneID"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:107814", 
            "id": "107814", 
            "database": "MGI"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A2AQ07", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 50441.0, 
        "chemical_mass": 50441.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AQ07", 
            "name": "Tubb1; 2810484G07Rik; M(beta)1.", 
            "locus": {
                "end_pos": 174457882, 
                "start_pos": 174450695, 
                "chromosome": "2", 
                "evidence": [
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                        "id": "ENSMUSG00000016255", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}