{
    "uniprot_canonical_ac": "A5HK05-1", 
    "sequence": {
        "header": "sp|A5HK05-1|APBP2_RAT Isoform 1 of Amyloid protein-binding protein 2  OS=Rattus norvegicus OX=10116 GN=Appbp2 PE=2 SV=1 CANONICAL=A5HK05-1", 
        "length": 585, 
        "sequence": "MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANRAALYGELCALLFAKSHYDEAYKWCVEAMKEITSGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSTGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVNSSPQSTEEVVQSFLMSQNVEGPSC"
    }, 
    "uniprot_id": "APBP2_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "amyloid protein-binding protein 2", 
                "protein interacting with APP tail 1; APP-BP2; amyloid beta precursor protein (cytoplasmic tail) binding protein 2"
            ], 
            "uniprotkb": [
                "Amyloid protein-binding protein 2", 
                "Amyloid beta precursor protein-binding protein 2", 
                "APP-BP2"
            ]
        }, 
        "gene": {
            "refseq": [
                "Appbp2", 
                "PAT1"
            ], 
            "uniprotkb": [
                "Appbp2", 
                "PAT1"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A5HK05", 
                    "id": "A5HK05", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Amyloid protein-binding protein 2; Amyloid beta precursor protein-binding protein 2; APP-BP2."
    }, 
    "publication": [
        {
            "title": "PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/9843960", 
            "journal": "Proceedings of the National Academy of Sciences of the United States of America", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094439.1", 
                    "id": "NP_001094439.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Zheng P, Eastman J, Vande Pol S, Pimplikar SW", 
            "date": "1998", 
            "pmid": "9843960"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A5HK05#A5HK05-1", 
            "isoform_ac": "A5HK05-1", 
            "locus": {
                "end_pos": 72507703, 
                "start_pos": 72544868, 
                "chromosome": "10", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000033684", 
                        "id": "ENSRNOT00000033684", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000032753", 
                        "id": "ENSRNOP00000032753", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A5HK05-1|APBP2_RAT Isoform 1 of Amyloid protein-binding protein 2  OS=Rattus norvegicus OX=10116 GN=Appbp2 PE=2 SV=1 CANONICAL=A5HK05-1", 
                "length": 585, 
                "sequence": "MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANRAALYGELCALLFAKSHYDEAYKWCVEAMKEITSGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSTGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVNSSPQSTEEVVQSFLMSQNVEGPSC"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:303396", 
            "resource": "KEGG Pathway", 
            "id": "rno:303396", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A5HK05#function", 
            "annotation": "May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A5HK05#function", 
                    "id": "A5HK05", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9DAX9-1", 
            "protein_name": "Amyloid protein-binding protein 2; Amyloid beta precursor protein-binding protein 2; APP-BP2.", 
            "sequence": {
                "length": 585, 
                "sequence": "MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANRAALYGELCALLFAKSHYDEAYKWCVEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSSSPQSTEEVVQSFLMAQNVEGPSC"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/31378", 
                    "id": "31378", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A5HK05/", 
                    "id": "A5HK05", 
                    "database": "OMA"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q92624-1", 
            "protein_name": "Amyloid protein-binding protein 2; Amyloid beta precursor protein-binding protein 2; APP-BP2; Protein interacting with APP tail 1.", 
            "sequence": {
                "length": 585, 
                "sequence": "MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/31378", 
                    "id": "31378", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A5HK05/", 
                    "id": "A5HK05", 
                    "database": "OMA"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094439.1", 
        "ac": "NP_001094439.1", 
        "name": "amyloid protein-binding protein 2; protein interacting with APP tail 1; APP-BP2; amyloid beta precursor protein (cytoplasmic tail) binding protein 2.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A5HK05", 
                                "id": "A5HK05", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A5HK05", 
                                "id": "A5HK05", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "microtubule", 
                        "id": "GO:0005874"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A5HK05", 
                                "id": "A5HK05", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasmic vesicle membrane", 
                        "id": "GO:0030659"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A5HK05", 
                                "id": "A5HK05", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "intracellular protein transport", 
                        "id": "GO:0006886"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 527, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 525
        }, 
        {
            "end_pos": 563, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 561
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094439.1", 
            "id": "NP_001094439.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:303396", 
            "id": "rno:303396", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000027654", 
            "id": "ENSRNOG00000027654", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/EHFGHKH/", 
            "id": "EHFGHKH", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", 
            "id": "IPR011990", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013026", 
            "id": "IPR013026", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", 
            "id": "IPR019734", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR042476", 
            "id": "IPR042476", 
            "database": "InterPro"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46575", 
            "id": "PTHR46575", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A5HK05", 
            "id": "PR_A5HK05", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/303396", 
            "id": "303396", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306488", 
            "id": "1306488", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A5HK05", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 66902.0, 
        "chemical_mass": 66902.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A5HK05", 
            "name": "Appbp2; PAT1.", 
            "locus": {
                "end_pos": 72503347, 
                "start_pos": 72545141, 
                "chromosome": "10", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000027654", 
                        "id": "ENSRNOG00000027654", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}