{ "uniprot_canonical_ac": "A3KGV1-1", "sequence": { "header": "sp|A3KGV1-1|ODFP2_MOUSE Isoform 1 of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 830, "sequence": "MSASSSGGSPRFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSQKVDELERKLEATSAQNVEFLQVIAKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKASYANVFGDAPYTSSYLTSSPIRSRSPPA" }, "uniprot_id": "ODFP2_MOUSE", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "outer dense fiber protein 2 isoform a", "outer dense fiber protein 2; cenexin; 84 kDa outer dense fiber protein; outer dense fiber of sperm tails protein 2" ], "uniprotkb": [ "Outer dense fiber protein 2", "Cenexin", "84 kDa outer dense fiber protein", "Outer dense fiber of sperm tails protein 2" ] }, "gene": { "refseq": [ "Odf2", "AI848335", "MMTEST29" ], "uniprotkb": [ "Odf2", "Odf84", "AI848335", "MMTEST29" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "recommendedname": { "full": "Outer dense fiber protein 2; Cenexin; 84 kDa outer dense fiber protein; Outer dense fiber of sperm tails protein 2." }, "publication": [ { "title": "The centrosome protein AKNA regulates neurogenesis via microtubule organization.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/30787442", "journal": "Nature", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "id": "NP_001106684.1", "database": "RefSeq" }, { "url": "https://www.uniprot.org/uniprot/A3KGV1/publications", "id": "A3KGV1", "database": "UniProtKB" } ], "authors": "Camargo Ortega G, Falk S, Johansson PA, Peyre E, Broix L, Sahu SK, Hirst W, Schlichthaerle T, De Juan Romero C, Draganova K, Vinopal S, Chinnappa K, Gavranovic A, Karakaya T, Steininger T, Merl-Pham J, Feederle R, Shao W, Shi SH, Hauck SM, Jungmann R, Bradke F, Borrell V, Geerlof A, Reber S, Tiwari VK, Huttner WB, Wilsch-Brauninger M, Nguyen L, Gotz M", "date": "2019", "pmid": "30787442" }, { "title": "Outer dense fibers stabilize the axoneme to maintain sperm motility.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/29168316", "journal": "Journal of cellular and molecular medicine", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "id": "NP_001106684.1", "database": "RefSeq" } ], "authors": "Zhao W, Li Z, Ping P, Wang G, Yuan X, Sun F", "date": "2018", "pmid": "29168316" }, { "title": "Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/29487109", "journal": "Development (Cambridge, England)", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "id": "NP_001106684.1", "database": "RefSeq" } ], "authors": "Wang C, Li J, Takemaru KI, Jiang X, Xu G, Wang B", "date": "2018", "pmid": "29487109" }, { "title": "A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/28292423", "journal": "Developmental cell", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "id": "NP_001106684.1", "database": "RefSeq" } ], "authors": "Minegishi K, Hashimoto M, Ajima R, Takaoka K, Shinohara K, Ikawa Y, Nishimura H, McMahon AP, Willert K, Okada Y, Sasaki H, Shi D, Fujimori T, Ohtsuka T, Igarashi Y, Yamaguchi TP, Shimono A, Shiratori H, Hamada H", "date": "2017", "pmid": "28292423" }, { "title": "Testis-specific serine/threonine protein kinase 4 (Tssk4) phosphorylates Odf2 at Ser-76.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/26961893", "journal": "Sci. Rep.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1/publications", "id": "A3KGV1", "database": "UniProtKB" } ], "authors": "Chen S., Fu G., Li H., Wang X., Wang Y., Yu L., Wei Y., Du S.", "date": "2016", "pmid": "26961893" }, { "title": "Tssk4 is essential for maintaining the structural integrity of sperm flagellum.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/25361759", "journal": "Mol. Hum. Reprod.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1/publications", "id": "A3KGV1", "database": "UniProtKB" } ], "authors": "Chen S., Fu G., Li H., Wang X., Wang Z., Yu L., Lin G., Wei Y., Saiyin H.", "date": "2015", "pmid": "25361759" }, { "title": "Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/23386061", "journal": "EMBO J.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1/publications", "id": "A3KGV1", "database": "UniProtKB" } ], "authors": "Reiter J.F., Garcia-Verdugo J.M., Kodani A., Salome Sirerol-Piquer M., Seol A.", "date": "2013", "pmid": "23386061" }, { "title": "Odf2-deficient mother centrioles lack distal/subdistal appendages and the ability to generate primary cilia.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/15852003", "journal": "Nat. Cell Biol.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1/publications", "id": "A3KGV1", "database": "UniProtKB" } ], "authors": "Ishikawa H., Tsukita S., Kubo A., Tsukita S.'", "date": "2005", "pmid": "15852003" }, { "title": "BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/12520002", "journal": "Nucleic acids research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "id": "NP_001106684.1", "database": "RefSeq" } ], "authors": "Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE", "date": "2003", "pmid": "12520002" }, { "title": "Exchangeable gene trap using the Cre/mutated lox system.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/10512203", "journal": "Cellular and molecular biology (Noisy-le-Grand, France)", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "id": "NP_001106684.1", "database": "RefSeq" } ], "authors": "Araki K, Imaizumi T, Sekimoto T, Yoshinobu K, Yoshimuta J, Akizuki M, Miura K, Araki M, Yamamura K", "date": "1999", "pmid": "10512203" }, { "title": "Mouse Odf2 cDNAs consist of evolutionary conserved as well as highly variable sequences and encode outer dense fiber proteins of the sperm tail.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/9740324", "journal": "Molecular reproduction and development", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "id": "NP_001106684.1", "database": "RefSeq" }, { "url": "https://www.uniprot.org/uniprot/A3KGV1/publications", "id": "A3KGV1", "database": "UniProtKB" } ], "authors": "Hoyer-Fender S, Petersen C, Brohmann H, Rhee K, Wolgemuth DJ", "date": "1998", "pmid": "9740324" }, { "title": "Interactional cloning of the 84-kDa major outer dense fiber protein Odf84. Leucine zippers mediate associations of Odf84 and Odf27.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/9045620", "journal": "J. Biol. Chem.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1/publications", "id": "A3KGV1", "database": "UniProtKB" } ], "authors": "Shao X., van der Hoorn F.A., Oko R., Tarnasky H.A., Schalles U.", "date": "1997", "pmid": "9045620" } ], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGV1-1", "isoform_ac": "A3KGV1-1", "locus": { "end_pos": 29890971, "start_pos": 29930658, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000113765", "id": "ENSMUST00000113765", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000109394", "id": "ENSMUSP00000109394", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A3KGV1-1|ODFP2_MOUSE Isoform 1 of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 830, "sequence": "MSASSSGGSPRFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSQKVDELERKLEATSAQNVEFLQVIAKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKASYANVFGDAPYTSSYLTSSPIRSRSPPA" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#F6Y325-1", "isoform_ac": "F6Y325-1", "locus": { "end_pos": 29889834, "start_pos": 29904078, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000137558", "id": "ENSMUST00000137558", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000117887", "id": "ENSMUSP00000117887", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F6Y325-1|ODFP2_MOUSE Computationally mapped isoform of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 271, "sequence": "XPRRLHGTTLASDFNDFIRRRFWAQPCRSWFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKNPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLR" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGV1-2", "isoform_ac": "A3KGV1-2", "locus": { "end_pos": 29893047, "start_pos": 29930658, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000113757", "id": "ENSMUST00000113757", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000109386", "id": "ENSMUSP00000109386", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A3KGV1-2|ODFP2_MOUSE Isoform 2 of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 806, "sequence": "MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMKGDTVNVRRSVRVKTKNPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSQKVDELERKLEATSAQNVEFLQVIAKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKASYANVFGDAPYTSSYLTSSPIRSRSPPA" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGV9-1", "isoform_ac": "A3KGV9-1", "locus": { "end_pos": 29890971, "start_pos": 29922431, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000113762", "id": "ENSMUST00000113762", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000109391", "id": "ENSMUSP00000109391", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A3KGV9-1|ODFP2_MOUSE Computationally mapped isoform of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 657, "sequence": "MSASSSGGSPRFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRVRDWQKGSHELARAGARLPR" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGV1-3", "isoform_ac": "A3KGV1-3", "locus": { "end_pos": 29893047, "start_pos": 29930658, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000046571", "id": "ENSMUST00000046571", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000049272", "id": "ENSMUSP00000049272", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A3KGV1-3|ODFP2_MOUSE Isoform 3 of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 825, "sequence": "MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSQKVDELERKLEATSAQNVEFLQVIAKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKASYANVFGDAPYTSSYLTSSPIRSRSPPA" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGV3-1", "isoform_ac": "A3KGV3-1", "locus": { "end_pos": 29893047, "start_pos": 29902246, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000133233", "id": "ENSMUST00000133233", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000117628", "id": "ENSMUSP00000117628", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A3KGV3-1|ODFP2_MOUSE Computationally mapped isoform of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 138, "sequence": "MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMKGDTVNVRRSVRVKTKNPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEEL" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGV1-4", "isoform_ac": "A3KGV1-4", "locus": { "end_pos": 29893047, "start_pos": 29930658, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000113759", "id": "ENSMUST00000113759", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000109388", "id": "ENSMUSP00000109388", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A3KGV1-4|ODFP2_MOUSE Isoform 4 of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 826, "sequence": "MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEKDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSQKVDELERKLEATSAQNVEFLQVIAKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKASYANVFGDAPYTSSYLTSSPIRSRSPPA" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#V9GXZ0-1", "isoform_ac": "V9GXZ0-1", "locus": { "end_pos": 29893047, "start_pos": 29926083, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000184845", "id": "ENSMUST00000184845", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000139390", "id": "ENSMUSP00000139390", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|V9GXZ0-1|ODFP2_MOUSE Computationally mapped isoform of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 680, "sequence": "MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRETGGYQRPECRVPTGDCQEGGGNPPGSAAVGGENEGVWVIGEAVGECH" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGV1-5", "isoform_ac": "A3KGV1-5", "locus": { "end_pos": 29893047, "start_pos": 29922431, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000113755", "id": "ENSMUST00000113755", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000109384", "id": "ENSMUSP00000109384", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A3KGV1-5|ODFP2_MOUSE Isoform 5 of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 652, "sequence": "MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRVRDWQKGSHELARAGARLPR" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGV2-1", "isoform_ac": "A3KGV2-1", "locus": { "end_pos": 29893047, "start_pos": 29901106, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000123335", "id": "ENSMUST00000123335", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000121207", "id": "ENSMUSP00000121207", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A3KGV2-1|ODFP2_MOUSE Computationally mapped isoform of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 69, "sequence": "MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMKGDTVNVRRSVRVKTKNPPHCLEITP" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGV1-6", "isoform_ac": "A3KGV1-6", "locus": { "end_pos": 29890971, "start_pos": 29922431, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000113764", "id": "ENSMUST00000113764", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000109393", "id": "ENSMUSP00000109393", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A3KGV1-6|ODFP2_MOUSE Isoform 6 of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 638, "sequence": "MSASSSGGSPRFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKNPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRVRDWQKGSHELARAGARLPR" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGW0-1", "isoform_ac": "A3KGW0-1", "locus": { "end_pos": 29889758, "start_pos": 29922431, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000113767", "id": "ENSMUST00000113767", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000109396", "id": "ENSMUSP00000109396", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A3KGW0-1|ODFP2_MOUSE Computationally mapped isoform of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 701, "sequence": "MGELPTGCRKRRRKRGGAAAGAGLHPPRRLHGTTLASDFNDFIRRRFWAQPCRSWFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRVRDWQKGSHELARAGARLPR" } }, { "url": "https://www.uniprot.org/uniprot/A3KGV1#A3KGV1-7", "isoform_ac": "A3KGV1-7", "locus": { "end_pos": 0, "start_pos": 0, "chromosome": "", "evidence": [] }, "sequence": { "header": "sp|A3KGV1-7|ODFP2_MOUSE Isoform 7 of Outer dense fiber protein 2 OS=Mus musculus OX=10090 GN=Odf2 PE=1 SV=1 CANONICAL=A3KGV1-1", "length": 610, "sequence": "MKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRVRDWQKGSHELARAGARLPR" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:18286", "resource": "KEGG Pathway", "id": "mmu:18286", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2565942", "resource": "Reactome", "id": "R-MMU-2565942", "name": "Regulation of PLK1 Activity at G2/M Transition" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-380259", "resource": "Reactome", "id": "R-MMU-380259", "name": "Loss of Nlp from mitotic centrosomes" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-380270", "resource": "Reactome", "id": "R-MMU-380270", "name": "Recruitment of mitotic centrosome proteins and complexes" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-380284", "resource": "Reactome", "id": "R-MMU-380284", "name": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-380320", "resource": "Reactome", "id": "R-MMU-380320", "name": "Recruitment of NuMA to mitotic centrosomes" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5620912", "resource": "Reactome", "id": "R-MMU-5620912", "name": "Anchoring of the basal body to the plasma membrane" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8854518", "resource": "Reactome", "id": "R-MMU-8854518", "name": "AURKA Activation by TPX2" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1#function", "annotation": "Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1#function", "id": "A3KGV1", "database": "UniProtKB" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "annotation": "Data show that the percentage of outer dense fiber of sperm tails 2 protein (ODF2) defects was higher in asthenozoospermic samples than that in control samples and was significantly correlated with the percentage of axoneme defects and non-motile sperm.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "id": "NP_001106684.1", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q5BJF6-1", "protein_name": "Outer dense fiber protein 2; Cenexin; Outer dense fiber of sperm tails protein 2.", "sequence": { "length": 829, "sequence": "MSASSSGGSPRFPSCGKNGVTSLTQKKVLRAPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARPVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERMKEEKDFTILQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTELSQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDGPYSTFLTSSPIRSRSPPA" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/1907", "id": "1907", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "ac": "NP_001106684.1", "name": "outer dense fiber protein 2 isoform a; outer dense fiber protein 2; cenexin; 84 kDa outer dense fiber protein; outer dense fiber of sperm tails protein 2.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "structural constituent of cytoskeleton", "id": "GO:0005200" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017137", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "Rab GTPase binding", "id": "GO:0017137" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "centrosome", "id": "GO:0005813" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "cilium", "id": "GO:0005929" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "cilium", "id": "GO:0005929" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "sperm flagellum", "id": "GO:0036126" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "sperm flagellum", "id": "GO:0036126" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "centriole", "id": "GO:0005814" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "centriole", "id": "GO:0005814" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097539", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "ciliary transition fiber", "id": "GO:0097539" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001520", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "outer dense fiber", "id": "GO:0001520" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "spindle pole", "id": "GO:0000922" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "microtubule", "id": "GO:0005874" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "ciliary basal body", "id": "GO:0036064" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120103", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "centriolar subdistal appendage", "id": "GO:0120103" } ], "total": 13, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007275", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "multicellular organism development", "id": "GO:0007275" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "spermatid development", "id": "GO:0007286" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "protein localization", "id": "GO:0008104" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "regulation of cilium assembly", "id": "GO:1902017" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010457", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "centriole-centriole cohesion", "id": "GO:0010457" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "id": "A3KGV1", "database": "UniProtKB" } ], "name": "cilium organization", "id": "GO:0044782" } ], "total": 6, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 269, "annotation": "n_glycosylation_sequon", "start_pos": 267 }, { "end_pos": 792, "annotation": "n_glycosylation_sequon", "start_pos": 790 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106684.1", "id": "NP_001106684.1", "database": "RefSeq" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2565942", "id": "R-MMU-2565942", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-380259", "id": "R-MMU-380259", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-380270", "id": "R-MMU-380270", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-380284", "id": "R-MMU-380284", "database": "Reactome" }, { "url": 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"url": "https://www.ebi.ac.uk/intact/interactors/id:A3KGV1*", "id": "A3KGV1", "database": "IntAct" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/18286", "id": "18286", "database": "GeneID" }, { "url": "http://www.informatics.jax.org/marker/MGI:1098824", "id": "1098824", "database": "MGI" } ], "expression_disease": [], "uniprot_ac": "A3KGV1", "disease": [], "mass": { "monoisotopic_mass": 95541.0, "chemical_mass": 95541.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A3KGV1", "name": "Odf2; Odf84; AI848335; MMTEST29.", "locus": { "end_pos": 29931746, "start_pos": 29889221, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000026790", "id": "ENSMUSG00000026790", "database": "Ensembl Gene" } ] } } ] }