{
    "uniprot_canonical_ac": "A2RUQ5-1", 
    "sequence": {
        "header": "sp|A2RUQ5-1|CQ102_HUMAN Isoform 1 of Uncharacterized protein C17orf102  OS=Homo sapiens OX=9606 GN=C17orf102 PE=2 SV=1 CANONICAL=A2RUQ5-1", 
        "length": 167, 
        "sequence": "MFDFSFPTPASAGTRMGPASCGGRSLHLPQLRFSRVDATAVTDVPFQRMHAPHRAPEVFCSRSSRGAGRGHPTPTPRVRWALAGNQPRCCAQLLSGRGGSGAQLRAGWVRGAAVGNLFILLLGKEDGEEEGTVLSYSSMVHISNITGIVGTTVSRTKPALVLMELTF"
    }, 
    "uniprot_id": "CQ102_HUMAN", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [], 
            "uniprotkb": [
                "Uncharacterized protein C17orf102"
            ]
        }, 
        "gene": {
            "refseq": [], 
            "uniprotkb": [
                "C17orf102"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RUQ5", 
                    "id": "A2RUQ5", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Uncharacterized protein C17orf102."
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [
        {
            "start_pos": 131, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUQ5", 
                    "id": "A2RUQ5", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.1", 
            "annotation": "Filters passed (1/5): patient freq. (2.1%).", 
            "sequence_org": "G", 
            "disease": {
                "doid": "2531", 
                "url": "http://disease-ontology.org/term/DOID:2531", 
                "icd10": "", 
                "name": "Hematologic cancer"
            }, 
            "sequence_mut": "V", 
            "subjects_tested": "48", 
            "end_pos": 131, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 11, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUQ5", 
                    "id": "A2RUQ5", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.1", 
            "annotation": "Filters passed (1/5): patient freq. (1.1%).", 
            "sequence_org": "S", 
            "disease": {
                "doid": "2394", 
                "url": "http://disease-ontology.org/term/DOID:2394", 
                "icd10": "", 
                "name": "Ovarian cancer"
            }, 
            "sequence_mut": "R", 
            "subjects_tested": "93", 
            "end_pos": 11, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 167, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUQ5", 
                    "id": "A2RUQ5", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.1", 
            "annotation": "Filters passed (1/5): patient freq. (1.1%).", 
            "sequence_org": "F", 
            "disease": {
                "doid": "9256", 
                "url": "http://disease-ontology.org/term/DOID:9256", 
                "icd10": "", 
                "name": "Colorectal cancer"
            }, 
            "sequence_mut": "L", 
            "subjects_tested": "94", 
            "end_pos": 167, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 60, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUQ5", 
                    "id": "A2RUQ5", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.4", 
            "annotation": "Filters passed (1/5): patient freq. (1.4%).", 
            "sequence_org": "C", 
            "disease": {
                "doid": "1612", 
                "url": "http://disease-ontology.org/term/DOID:1612", 
                "icd10": "", 
                "name": "Breast cancer"
            }, 
            "sequence_mut": "Y", 
            "subjects_tested": "72", 
            "end_pos": 60, 
            "type": "Point mutation"
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RUQ5#A2RUQ5-1", 
            "isoform_ac": "A2RUQ5-1", 
            "locus": {
                "end_pos": 0, 
                "start_pos": 0, 
                "chromosome": "", 
                "evidence": []
            }, 
            "sequence": {
                "header": "sp|A2RUQ5-1|CQ102_HUMAN Isoform 1 of Uncharacterized protein C17orf102  OS=Homo sapiens OX=9606 GN=C17orf102 PE=2 SV=1 CANONICAL=A2RUQ5-1", 
                "length": 167, 
                "sequence": "MFDFSFPTPASAGTRMGPASCGGRSLHLPQLRFSRVDATAVTDVPFQRMHAPHRAPEVFCSRSSRGAGRGHPTPTPRVRWALAGNQPRCCAQLLSGRGGSGAQLRAGWVRGAAVGNLFILLLGKEDGEEEGTVLSYSSMVHISNITGIVGTTVSRTKPALVLMELTF"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {}, 
    "site_annotation": [
        {
            "end_pos": 146, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 144
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997337.2", 
            "id": "NP_997337.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=34412", 
            "id": "34412", 
            "database": "HGNC"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A2RUQ5", 
            "id": "A2RUQ5", 
            "database": "PHAROS"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A2RUQ5", 
            "id": "NX_A2RUQ5", 
            "database": "neXtProt"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=C17orf102", 
            "id": "C17orf102", 
            "database": "GeneCards"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2RUQ5", 
            "id": "PR_A2RUQ5", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A2RUQ5*", 
            "id": "A2RUQ5", 
            "database": "IntAct"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A2RUQ5", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 17761.0, 
        "chemical_mass": 17761.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RUQ5", 
            "name": "C17orf102.", 
            "locus": {
                "end_pos": 34574123, 
                "start_pos": 34579369, 
                "chromosome": "17", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000197322", 
                        "id": "ENSG00000197322", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}