{
    "uniprot_canonical_ac": "A2RUH7-1", 
    "sequence": {
        "header": "sp|A2RUH7-1|MBPHL_HUMAN Isoform 1 of Myosin-binding protein H-like  OS=Homo sapiens OX=9606 GN=MYBPHL PE=1 SV=2 CANONICAL=A2RUH7-1", 
        "length": 354, 
        "sequence": "MEAATAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN"
    }, 
    "uniprot_id": "MBPHL_HUMAN", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "myosin-binding protein H-like isoform 1"
            ], 
            "uniprotkb": [
                "Myosin-binding protein H-like"
            ]
        }, 
        "gene": {
            "refseq": [
                "MYBPHL"
            ], 
            "uniprotkb": [
                "MYBPHL"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Myosin-binding protein H-like."
    }, 
    "publication": [
        {
            "title": "Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/28778945", 
            "journal": "Circulation", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001010985.2", 
                    "id": "NP_001010985.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Barefield DY, Puckelwartz MJ, Kim EY, Wilsbacher LD, Vo AH, Waters EA, Earley JU, Hadhazy M, Dellefave-Castillo L, Pesce LL, McNally EM", 
            "date": "2017", 
            "pmid": "28778945"
        }
    ], 
    "glycosylation": [], 
    "mutation": [
        {
            "start_pos": 17, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.0", 
            "annotation": "Filters passed (1/5): patient freq. (1.0%).", 
            "sequence_org": "V", 
            "disease": {
                "doid": "11054", 
                "url": "http://disease-ontology.org/term/DOID:11054", 
                "icd10": "", 
                "name": "Urinary bladder cancer"
            }, 
            "sequence_mut": "G", 
            "subjects_tested": "103", 
            "end_pos": 17, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 294, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "W", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "*", 
            "subjects_tested": "50", 
            "end_pos": 294, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 155, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.1", 
            "annotation": "Filters passed (1/5): patient freq. (1.1%).", 
            "sequence_org": "V", 
            "disease": {
                "doid": "9256", 
                "url": "http://disease-ontology.org/term/DOID:9256", 
                "icd10": "", 
                "name": "Colorectal cancer"
            }, 
            "sequence_mut": "M", 
            "subjects_tested": "94", 
            "end_pos": 155, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 275, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "G", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "V", 
            "subjects_tested": "50", 
            "end_pos": 275, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 99, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "V", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "A", 
            "subjects_tested": "50", 
            "end_pos": 99, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 141, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "L", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "P", 
            "subjects_tested": "50", 
            "end_pos": 141, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 340, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "G", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "V", 
            "subjects_tested": "50", 
            "end_pos": 340, 
            "type": "Point mutation"
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RUH7#A2RUH7-1", 
            "isoform_ac": "A2RUH7-1", 
            "locus": {
                "end_pos": 109294242, 
                "start_pos": 109306991, 
                "chromosome": "1", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000357155", 
                        "id": "ENST00000357155", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000349678", 
                        "id": "ENSP00000349678", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2RUH7-1|MBPHL_HUMAN Isoform 1 of Myosin-binding protein H-like  OS=Homo sapiens OX=9606 GN=MYBPHL PE=1 SV=2 CANONICAL=A2RUH7-1", 
                "length": 354, 
                "sequence": "MEAATAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RUH7#A2RUH7-2", 
            "isoform_ac": "A2RUH7-2", 
            "locus": {
                "end_pos": 0, 
                "start_pos": 0, 
                "chromosome": "", 
                "evidence": []
            }, 
            "sequence": {
                "header": "sp|A2RUH7-2|MBPHL_HUMAN Isoform 2 of Myosin-binding protein H-like  OS=Homo sapiens OX=9606 GN=MYBPHL PE=1 SV=2 CANONICAL=A2RUH7-1", 
                "length": 331, 
                "sequence": "MEAATAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:343263", 
            "resource": "KEGG Pathway", 
            "id": "hsa:343263", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001010985.2", 
            "annotation": "MYBPHL truncations may increase risk for human arrhythmias and cardiomyopathy.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001010985.2", 
                    "id": "NP_001010985.2", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q5FW53-1", 
            "protein_name": "Myosin-binding protein H-like.", 
            "sequence": {
                "length": 355, 
                "sequence": "METATTLEIASCSQRQVEAAADPADAKGPRTSHQQEAGSPSLQLLPSIEEHPKIWLPRALKQTYIRKAGETVNLLIPIQGKPKPQTTWTHNGCALDSSRVSVRNGEHDSILFIREAQRTDSGCYQLCVQLGGLQATATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTGNTALLGYTVQKADKKSGLWFTVLERYHRTSCVVSNLIVGNSYAFRVFAENQCGLSDTAPVTADLAHIQKAATVYKAKGFAQRDLSEAPKFTQPLADCTTVTGYDTQLFCCVRASPRPKIIWLKNKMDLQGNPKYRALSQLGICSLEIRKPSPFDGGIYTCKAINALGEASVDCRVDVKAPH"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A2RUH7/", 
                    "id": "A2RUH7", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/19221", 
                    "id": "19221", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q5PQM4-1", 
            "protein_name": "Myosin-binding protein H-like.", 
            "sequence": {
                "length": 355, 
                "sequence": "METATTLEIASCSQRQVEEAADPADAEGPQTTRQQEAGSPSLQLLPSIEEHPKIWLPRALRQTYIRKVGETVNLLIPFQGKPKPQTIWTHNGSALDNSRVSVRNGEHDSILFIREAQRTDSGCYQLCVQLGGLQATATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTGNTALLGYTVQKADKKSGLWFTVLERYHRTSCIVSDLIVGNSYAFRVFAENQCGLSDTAPVTADLAHIQKAATVYKAKGFAQRDLSEAPKFTQPLADCTTVTGYDTQLFCCVRASPKPKIIWLKNKMDLQGNPKYRALSQLGICSLEIRKPSPFDGGIYTCKAINALGEASVDCRVDVKAPH"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A2RUH7/", 
                    "id": "A2RUH7", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/19221", 
                    "id": "19221", 
                    "database": "MGI"
                }
            ], 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001010985.2", 
        "ac": "NP_001010985.2", 
        "name": "myosin-binding protein H-like isoform 1.", 
        "summary": "This gene encodes a protein with two immunoglobulin superfamily domains and a fibronectin 3 domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]."
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RUH7", 
                                "id": "A2RUH7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "in utero embryonic development", 
                        "id": "GO:0001701"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001010985.2", 
            "id": "NP_001010985.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=30434", 
            "id": "30434", 
            "database": "HGNC"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A2RUH7", 
            "id": "A2RUH7", 
            "database": "PHAROS"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A2RUH7", 
            "id": "NX_A2RUH7", 
            "database": "neXtProt"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=MYBPHL", 
            "id": "MYBPHL", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:343263", 
            "id": "hsa:343263", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000221986", 
            "id": "ENSG00000221986", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/DVWGFSA/", 
            "id": "DVWGFSA", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", 
            "id": "cd00063", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", 
            "id": "IPR003598", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", 
            "id": "IPR003599", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", 
            "id": "IPR007110", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", 
            "id": "IPR013783", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", 
            "id": "IPR036179", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", 
            "id": "IPR013098", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", 
            "id": "IPR003961", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", 
            "id": "IPR036116", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF07679", 
            "id": "PF07679", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00041", 
            "id": "PF00041", 
            "database": "Pfam"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2RUH7", 
            "id": "PR_A2RUH7", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A2RUH7*", 
            "id": "A2RUH7", 
            "database": "IntAct"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/343263", 
            "id": "343263", 
            "database": "GeneID"
        }
    ], 
    "expression_disease": [
        {
            "trend": "Up", 
            "disease": {
                "doid": "3571", 
                "url": "http://disease-ontology.org/term/DOID:3571", 
                "icd10": "", 
                "name": "DOID:3571 / Liver cancer [Livca]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "3910", 
                "url": "http://disease-ontology.org/term/DOID:3910", 
                "icd10": "", 
                "name": "DOID:3910 / Lung adenocarcinoma"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "10283", 
                "url": "http://disease-ontology.org/term/DOID:10283", 
                "icd10": "", 
                "name": "DOID:10283 / Prostate cancer [PCa]"
            }, 
            "significant": "Yes", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "3907", 
                "url": "http://disease-ontology.org/term/DOID:3907", 
                "icd10": "", 
                "name": "DOID:3907 / Lung squamous cell carcinoma"
            }, 
            "significant": "Yes", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Up", 
            "disease": {
                "doid": "5041", 
                "url": "http://disease-ontology.org/term/DOID:5041", 
                "icd10": "", 
                "name": "DOID:5041 / Esophageal cancer [EC]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Up", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "DOID:1781 / Thyroid cancer [Thyca]"
            }, 
            "significant": "Yes", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "11054", 
                "url": "http://disease-ontology.org/term/DOID:11054", 
                "icd10": "", 
                "name": "DOID:11054 / Urinary bladder cancer [UBC]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RUH7", 
                    "id": "A2RUH7", 
                    "database": "BioXpress"
                }
            ]
        }
    ], 
    "uniprot_ac": "A2RUH7", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 38733.0, 
        "chemical_mass": 38733.0
    }, 
    "expression_tissue": [
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0009853", 
                "uberon": "0009853", 
                "name": "Body of uterus"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000221986", 
                    "id": "ENSG00000221986", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000458", 
                "uberon": "0000458", 
                "name": "Endocervix"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000221986", 
                    "id": "ENSG00000221986", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000948", 
                "uberon": "0000948", 
                "name": "Heart"
            }, 
            "present": "yes", 
            "evidence": [
                {
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                    "id": "ENSG00000221986", 
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                "uberon": "0002369", 
                "name": "Adrenal gland"
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            "evidence": [
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                    "id": "ENSG00000221986", 
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        {
            "tissue": {
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                "name": "Ovary"
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                    "id": "ENSG00000221986", 
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        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000996", 
                "uberon": "0000996", 
                "name": "Vagina"
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            "evidence": [
                {
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                    "id": "ENSG00000221986", 
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        {
            "tissue": {
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                "uberon": "0001155", 
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            "evidence": [
                {
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        {
            "tissue": {
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                "uberon": "0001987", 
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            "evidence": [
                {
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                    "id": "ENSG00000221986", 
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        {
            "tissue": {
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                "name": "Brain"
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        {
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        {
            "tissue": {
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                "name": "Body of pancreas"
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                    "id": "ENSG00000221986", 
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        {
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            "evidence": [
                {
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                    "id": "ENSG00000221986", 
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        {
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                "url": "http://purl.obolibrary.org/obo/UBERON_0000007", 
                "uberon": "0000007", 
                "name": "Pituitary gland"
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            "evidence": [
                {
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        {
            "tissue": {
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                    "id": "ENSG00000221986", 
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        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002046", 
                "uberon": "0002046", 
                "name": "Thyroid gland"
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            "evidence": [
                {
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                    "id": "ENSG00000221986", 
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        {
            "tissue": {
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                "uberon": "0000178", 
                "name": "Blood"
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                {
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                    "id": "ENSG00000221986", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
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                "uberon": "0001043", 
                "name": "Esophagus"
            }, 
            "present": "yes", 
            "evidence": [
                {
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                    "id": "ENSG00000221986", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002367", 
                "uberon": "0002367", 
                "name": "Prostate gland"
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            "present": "yes", 
            "evidence": [
                {
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                    "id": "ENSG00000221986", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001161", 
                "uberon": "0001161", 
                "name": "Body of stomach"
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            "evidence": [
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                    "id": "ENSG00000221986", 
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001255", 
                "uberon": "0001255", 
                "name": "Urinary bladder"
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            "evidence": [
                {
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                    "id": "ENSG00000221986", 
                    "database": "Bgee"
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            ]
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    ], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RUH7", 
            "name": "MYBPHL.", 
            "locus": {
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                "start_pos": 109307041, 
                "chromosome": "1", 
                "evidence": [
                    {
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                        "id": "ENSG00000221986", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}