{
    "uniprot_canonical_ac": "A2BHR0-1", 
    "sequence": {
        "header": "tr|A2BHR0-1|A2BHR0_MOUSE Isoform 1 of Odorant-binding protein 2B  OS=Mus musculus OX=10090 GN=Obp2b PE=3 SV=1 CANONICAL=A2BHR0-1", 
        "length": 176, 
        "sequence": "MKSLLLTILLLGLVAVLKAQEAPPDDLEDFSGIWYTQAMVSDRNHTDGKRPMKVFPMTVIALEGGSLEAQLTFWDNGHCHMKKILMHKTDEPHKYTAFKGKKTIYIQETSVKGYYILYCEGQRHGRSHRKGKLIGTNSEKNPEAMEEFKKFAMSKGFREENIIVPEQLDQCVSGSN"
    }, 
    "uniprot_id": "A2BHR0_MOUSE", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "odorant-binding protein 2a precursor", 
                "novel lipocalin protein; lipocalin 14"
            ], 
            "uniprotkb": [
                "Odorant-binding protein 2B"
            ]
        }, 
        "gene": {
            "refseq": [
                "Obp2b", 
                "Lcn14"
            ], 
            "uniprotkb": [
                "Obp2b", 
                "Lcn14"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2BHR0", 
                    "id": "A2BHR0", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "recommendedname": {
        "full": "Odorant-binding protein 2B."
    }, 
    "publication": [
        {
            "title": "Adipose-derived lipocalin 14 alleviates hyperglycaemia by suppressing both adipocyte glycerol efflux and hepatic gluconeogenesis in mice.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/26592241", 
            "journal": "Diabetologia", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092771.1", 
                    "id": "NP_001092771.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Lee JT, Huang Z, Pan K, Zhang HJ, Woo CW, Xu A, Wong CM", 
            "date": "2016", 
            "pmid": "26592241"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2BHR0#A2BHR0-1", 
            "isoform_ac": "A2BHR0-1", 
            "locus": {
                "end_pos": 25737057, 
                "start_pos": 25739611, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000114192", 
                        "id": "ENSMUST00000114192", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000109830", 
                        "id": "ENSMUSP00000109830", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A2BHR0-1|A2BHR0_MOUSE Isoform 1 of Odorant-binding protein 2B  OS=Mus musculus OX=10090 GN=Obp2b PE=3 SV=1 CANONICAL=A2BHR0-1", 
                "length": 176, 
                "sequence": "MKSLLLTILLLGLVAVLKAQEAPPDDLEDFSGIWYTQAMVSDRNHTDGKRPMKVFPMTVIALEGGSLEAQLTFWDNGHCHMKKILMHKTDEPHKYTAFKGKKTIYIQETSVKGYYILYCEGQRHGRSHRKGKLIGTNSEKNPEAMEEFKKFAMSKGFREENIIVPEQLDQCVSGSN"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:383678", 
            "resource": "KEGG Pathway", 
            "id": "mmu:383678", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092771.1", 
            "annotation": "Reduced LCN14 expression is involved in the pathogenesis of obesity-related metabolic dysregulation. LCN14 exerts its beneficial effects on glucose homeostasis and insulin sensitivity via its actions in both adipocytes and hepatocytes.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092771.1", 
                    "id": "NP_001092771.1", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9NY56-1", 
            "protein_name": "Odorant-binding protein 2a; Odorant-binding protein IIa; OBPIIa.", 
            "sequence": {
                "length": 170, 
                "sequence": "MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVSPVKVTALGGGNLEATFTFMREDRCIQKKILMRKTEEPGKFSAYGGRKLIYLQELPGTDDYVFYCKDQRRGGLRYMGKLVGRNPNTNLEALEEFKKLVQHKGLSEEDIFMPLQTGSCVLEH"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/135821", 
                    "id": "135821", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092771.1", 
        "ac": "NP_001092771.1", 
        "name": "odorant-binding protein 2a precursor; novel lipocalin protein; lipocalin 14.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2BHR0", 
                                "id": "A2BHR0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "small molecule binding", 
                        "id": "GO:0036094"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 46, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 44
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092771.1", 
            "id": "NP_001092771.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:383678", 
            "id": "mmu:383678", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000079539", 
            "id": "ENSMUSG00000079539", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/KESCVPE/", 
            "id": "KESCVPE", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000566", 
            "id": "IPR000566", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012674", 
            "id": "IPR012674", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002345", 
            "id": "IPR002345", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002450", 
            "id": "IPR002450", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00061", 
            "id": "PF00061", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11430", 
            "id": "PTHR11430", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/383678", 
            "id": "383678", 
            "database": "GeneID"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:3651927", 
            "id": "3651927", 
            "database": "MGI"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A2BHR0", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 20008.0, 
        "chemical_mass": 20008.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2BHR0", 
            "name": "Obp2b; Lcn14.", 
            "locus": {
                "end_pos": 25740097, 
                "start_pos": 25737009, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000079539", 
                        "id": "ENSMUSG00000079539", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}