{ "uniprot_canonical_ac": "A2AJX0-1", "sequence": { "header": "tr|A2AJX0-1|A2AJX0_MOUSE Isoform 1 of Kelch-like 32 OS=Mus musculus OX=10090 GN=Klhl32 PE=4 SV=1 CANONICAL=A2AJX0-1", "length": 620, "sequence": "MPSEHCLSIQEMLTGQRLCHSETHNDTVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLRGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFHLTLLEKAVIDFLVKHLSELLKSRPEDVLTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHNCHYQHLDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAMDEYLYAVGGRNELCQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNGRIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTV" }, "uniprot_id": "A2AJX0_MOUSE", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "kelch-like protein 32 isoform 1", "BTB and kelch domain containing 5" ], "uniprotkb": [ "Kelch-like 32" ] }, "gene": { "refseq": [ "Klhl32", "6430524H05Rik", "D4Ertd389e", "Gm1356", "mKIAA1900" ], "uniprotkb": [ "Klhl32", "6430524H05Rik", "D4Ertd389e", "Gm1356", "mKIAA1900" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AJX0", "id": "A2AJX0", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "recommendedname": { "full": "Kelch-like 32." }, "publication": [ { "title": "Normal embryonic and germ cell development in mice lacking alpha 1,3-fucosyltransferase IX (Fut9) which show disappearance of stage-specific embryonic antigen 1.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/15121843", "journal": "Molecular and cellular biology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156492.1", "id": "NP_001156492.1", "database": "RefSeq" } ], "authors": "Kudo T, Kaneko M, Iwasaki H, Togayachi A, Nishihara S, Abe K, Narimatsu H", "date": "2004", "pmid": "15121843" } ], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2AJX0#A2AJX0-1", "isoform_ac": "A2AJX0-1", "locus": { "end_pos": 24617388, "start_pos": 24800828, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000108218", "id": "ENSMUST00000108218", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000103853", "id": "ENSMUSP00000103853", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A2AJX0-1|A2AJX0_MOUSE Isoform 1 of Kelch-like 32 OS=Mus musculus OX=10090 GN=Klhl32 PE=4 SV=1 CANONICAL=A2AJX0-1", "length": 620, "sequence": "MPSEHCLSIQEMLTGQRLCHSETHNDTVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLRGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFHLTLLEKAVIDFLVKHLSELLKSRPEDVLTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHNCHYQHLDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAMDEYLYAVGGRNELCQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNGRIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTV" } }, { "url": "https://www.uniprot.org/uniprot/A2AJX0#A2AJX1-1", "isoform_ac": "A2AJX1-1", "locus": { "end_pos": 24617388, "start_pos": 24800828, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000108214", "id": "ENSMUST00000108214", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000103849", "id": "ENSMUSP00000103849", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A2AJX1-1|A2AJX0_MOUSE Computationally mapped isoform of Kelch-like 32 OS=Mus musculus OX=10090 GN=Klhl32 PE=4 SV=1 CANONICAL=A2AJX0-1", "length": 358, "sequence": "MPSEHCLSIQEMLTGQRLCHSETHNDTVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLRGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFHLTLLEKAVIDFLVKHLSELLKSRPEDVLTLPYCLLQEVLKSDRLTSLSEEQIWQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNGRIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTV" } }, { "url": "https://www.uniprot.org/uniprot/A2AJX0#E9Q7Q2-1", "isoform_ac": "E9Q7Q2-1", "locus": { "end_pos": 24617388, "start_pos": 24800828, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000084781", "id": "ENSMUST00000084781", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000081839", "id": "ENSMUSP00000081839", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E9Q7Q2-1|A2AJX0_MOUSE Computationally mapped isoform of Kelch-like 32 OS=Mus musculus OX=10090 GN=Klhl32 PE=4 SV=1 CANONICAL=A2AJX0-1", "length": 587, "sequence": "MPSEHCLSIQEMLTGQRLCHSETHNDTVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLRGVTSLGLKQALEFAYTGQELNSFNYLDLYRLADLFHLTLLEKAVIDFLVKHLSELLKSRPEDVLTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHNCHYQHLDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAMDEYLYAVGGRNELCQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNGRIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTV" } }, { "url": "https://www.uniprot.org/uniprot/A2AJX0#J3QPI3-1", "isoform_ac": "J3QPI3-1", "locus": { "end_pos": 24632696, "start_pos": 24800828, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000140652", "id": "ENSMUST00000140652", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000137312", "id": "ENSMUSP00000137312", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|J3QPI3-1|A2AJX0_MOUSE Computationally mapped isoform of Kelch-like 32 OS=Mus musculus OX=10090 GN=Klhl32 PE=4 SV=1 CANONICAL=A2AJX0-1", "length": 139, "sequence": "MPSEHCLSIQEMLTGQRLCHSETHNDTVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLRGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQVG" } }, { "url": "https://www.uniprot.org/uniprot/A2AJX0#J3KML3-1", "isoform_ac": "J3KML3-1", "locus": { "end_pos": 24711574, "start_pos": 24743965, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000150920", "id": "ENSMUST00000150920", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000135917", "id": "ENSMUSP00000135917", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|J3KML3-1|A2AJX0_MOUSE Computationally mapped isoform of Kelch-like 32 OS=Mus musculus OX=10090 GN=Klhl32 PE=4 SV=1 CANONICAL=A2AJX0-1", "length": 50, "sequence": "AMFSLCMVESGADEVNLRGVTSLGLKQALEFAYTGQAMPLLQVCSLFLLL" } } ], "pathway": [], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q96NJ5-1", "protein_name": "Kelch-like protein 32; BTB and kelch domain-containing protein 5.", "sequence": { "length": 620, "sequence": "MPSERCLSIQEMLTGQRLCHSESHNDSVLAALNQQRSDGILCDITLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLHGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFNLTLLEKAVIDFLVKHLSELLKSRPEEVLTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHNCHYQYMDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAMEEYLYAVGGRNELRQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNGRIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTI" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A2AJX0/", "id": "A2AJX0", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/14173", "id": "14173", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "F1M9S9-1", "protein_name": "Kelch-like family member 32.", "sequence": { "length": 620, "sequence": "MPSEHCLSIQEMLTGQRLCHSESHNDTVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLRGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFHLTLLEKAVIDFLVKHLSELLKSRPEDVLTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHNCHYQHMDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAMDEYLYAVGGRNELRQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMAYEPKQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNGRIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTV" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A2AJX0/", "id": "A2AJX0", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/14173", "id": "14173", "database": "MGI" } ], "organism": "Rattus norvegicus", "tax_id": 10116 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156492.1", "ac": "NP_001156492.1", "name": "kelch-like protein 32 isoform 1; BTB and kelch domain containing 5.", "summary": "" }, "go_annotation": {}, "site_annotation": [ { "end_pos": 27, "annotation": "n_glycosylation_sequon", "start_pos": 25 }, { "end_pos": 327, "annotation": "n_glycosylation_sequon", "start_pos": 325 }, { "end_pos": 540, "annotation": "n_glycosylation_sequon", "start_pos": 538 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156492.1", "id": "NP_001156492.1", "database": "RefSeq" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000040387", "id": "ENSMUSG00000040387", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/ADQWTRC/", "id": "ADQWTRC", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "id": "IPR000210", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "id": "IPR011333", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "id": "IPR006652", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "id": "IPR015915", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "id": "IPR017096", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR030570", "id": "IPR030570", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "id": "IPR011705", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00651", "id": "PF00651", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF01344", "id": "PF01344", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF07707", "id": "PF07707", "database": "Pfam" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF16", "id": "PTHR45632:SF16", "database": "PANTHER" }, { "url": "https://www.ebi.ac.uk/intact/interactors/id:A2AJX0*", "id": "A2AJX0", "database": "IntAct" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/212390", "id": "212390", "database": "GeneID" }, { "url": "http://www.informatics.jax.org/marker/MGI:3612790", "id": "3612790", "database": "MGI" } ], "expression_disease": [], "uniprot_ac": "A2AJX0", "disease": [], "mass": { "monoisotopic_mass": 70260.0, "chemical_mass": 70260.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2AJX0", "name": "Klhl32; 6430524H05Rik; D4Ertd389e; Gm1356; mKIAA1900.", "locus": { "end_pos": 24612554, "start_pos": 24851124, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000040387", "id": "ENSMUSG00000040387", "database": "Ensembl Gene" } ] } } ] }