{
    "uniprot_canonical_ac": "A2A447-1", 
    "sequence": {
        "header": "tr|A2A447-1|A2A447_MOUSE Isoform 1 of Reproductive homeobox 2B  OS=Mus musculus OX=10090 GN=Rhox2b PE=4 SV=1 CANONICAL=A2A447-1", 
        "length": 191, 
        "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGPGLPGSGASAAEGYRAGEISAGGPAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKHVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL"
    }, 
    "uniprot_id": "A2A447_MOUSE", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "reproductive homeobox 2B", 
                "reproductive homeobox 2A"
            ], 
            "uniprotkb": [
                "Reproductive homeobox 2B"
            ]
        }, 
        "gene": {
            "refseq": [
                "Rhox2b", 
                "Rhox2.2", 
                "Rhox2a"
            ], 
            "uniprotkb": [
                "Rhox2b", 
                "Rhox2d", 
                "Rhox2.2", 
                "Rhox2a"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A447", 
                    "id": "A2A447", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "recommendedname": {
        "full": "Reproductive homeobox 2B."
    }, 
    "publication": [
        {
            "title": "Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/16465597", 
            "journal": "Mammalian genome : official journal of the International Mammalian Genome Society", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092786.1", 
                    "id": "NP_001092786.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Morris L, Gordon J, Blackburn CC", 
            "date": "2006", 
            "pmid": "16465597"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A447#A2A447-1", 
            "isoform_ac": "A2A447-1", 
            "locus": {
                "end_pos": 37412111, 
                "start_pos": 37416624, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000115191", 
                        "id": "ENSMUST00000115191", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000110845", 
                        "id": "ENSMUSP00000110845", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A2A447-1|A2A447_MOUSE Isoform 1 of Reproductive homeobox 2B  OS=Mus musculus OX=10090 GN=Rhox2b PE=4 SV=1 CANONICAL=A2A447-1", 
                "length": 191, 
                "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGPGLPGSGASAAEGYRAGEISAGGPAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKHVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:100039913", 
            "resource": "KEGG Pathway", 
            "id": "mmu:100039913", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "W4VSN9-1", 
            "protein_name": "Reproductive homeobox 2D; MCG125586.", 
            "sequence": {
                "length": 191, 
                "sequence": "MEQQSINYKLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGPGLPGSGVSAAEGYRAGELSAGGLASPVADLMDKSNQEDLSATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFRYSWQQSFNVLQLQELESIFQCNQYISTTEAKRLAKSMGVSEATVQEWFLKRREKYRSYKRL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/41772", 
                    "id": "41772", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "A2ANE0-1", 
            "protein_name": "MCG113260; Reproductive homeobox 2F.", 
            "sequence": {
                "length": 191, 
                "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/41772", 
                    "id": "41772", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "L7MUB9-1", 
            "protein_name": "Reproductive homeobox 2G.", 
            "sequence": {
                "length": 191, 
                "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/41772", 
                    "id": "41772", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "A2AWL9-1", 
            "protein_name": "Reproductive homeobox 2C.", 
            "sequence": {
                "length": 191, 
                "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/41772", 
                    "id": "41772", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q9D4Y3-1", 
            "protein_name": "Reproductive homeobox on X chromosome 2; Reproductive homeobox 2E; Reproductive homeobox 2A.", 
            "sequence": {
                "length": 191, 
                "sequence": "MERQSVNYKLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPEFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/41772", 
                    "id": "41772", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "K7N6P1-1", 
            "protein_name": "MCG119345; Reproductive homeobox 2H.", 
            "sequence": {
                "length": 191, 
                "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/41772", 
                    "id": "41772", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092786.1", 
        "ac": "NP_001092786.1", 
        "name": "reproductive homeobox 2B; reproductive homeobox 2A.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A447", 
                                "id": "A2A447", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA binding", 
                        "id": "GO:0003677"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A447", 
                                "id": "A2A447", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092786.1", 
            "id": "NP_001092786.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:100039913", 
            "id": "mmu:100039913", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000079638", 
            "id": "ENSMUSG00000079638", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/RWACTHP/", 
            "id": "RWACTHP", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", 
            "id": "cd00086", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", 
            "id": "IPR001356", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", 
            "id": "IPR009057", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00046", 
            "id": "PF00046", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/100039913", 
            "id": "100039913", 
            "database": "GeneID"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:3770262", 
            "id": "3770262", 
            "database": "MGI"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A2A447", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 21049.0, 
        "chemical_mass": 21049.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A447", 
            "name": "Rhox2b; Rhox2d; Rhox2.2; Rhox2a.", 
            "locus": {
                "end_pos": 37416806, 
                "start_pos": 37412067, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000079638", 
                        "id": "ENSMUSG00000079638", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}