{
    "uniprot_canonical_ac": "A2A368-1", 
    "sequence": {
        "header": "sp|A2A368-1|MAGBG_HUMAN Isoform 1 of Melanoma-associated antigen B16  OS=Homo sapiens OX=9606 GN=MAGEB16 PE=4 SV=2 CANONICAL=A2A368-1", 
        "length": 324, 
        "sequence": "MSQDQESPRCTHDQHLQTFSETQSLEVAQVSKALEKTLLSSSHPLVPGKLKEAPAAKAESPLEVPQSFCSSSIAVTTTSSSESDEASSNQEEEDSPSSSEDTSDPRNVPADALDQKVAFLVNFMLHKCQMKKPITKADMLKIIIKDDESHFSEILLRASEHLEMIFGLDVVEVDPTTHCYGLFIKLGLTYDGMLSGEKGVPKTGLLIIVLGVIFMKGNRATEEEVWEVLNLTGVYSGKKHFIFGEPRMLITKDFVKEKYLEYQQVANSDPARYEFLWGPRAKAETSKMKVLEFVAKVHGSYPHSFPSQYAEALKEEEERARARI"
    }, 
    "uniprot_id": "MAGBG_HUMAN", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "melanoma-associated antigen B16", 
                "melanoma antigen family B, 16 (pseudogene); MAGE-B16 antigen; melanoma antigen family B16"
            ], 
            "uniprotkb": [
                "Melanoma-associated antigen B16", 
                "MAGE-B16 antigen"
            ]
        }, 
        "gene": {
            "refseq": [
                "MAGEB16"
            ], 
            "uniprotkb": [
                "MAGEB16"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A368", 
                    "id": "A2A368", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Melanoma-associated antigen B16; MAGE-B16 antigen."
    }, 
    "publication": [
        {
            "title": "Demethylation of CpG islands in the 5' upstream regions mediates the expression of the human testis-specific gene MAGEB16 and its mouse homolog Mageb16.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/24219866", 
            "journal": "BMB reports", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093391.1", 
                    "id": "NP_001093391.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Liu Y, Wang M, Jiang S, Lu Y, Tao D, Yang Y, Ma Y, Zhang S", 
            "date": "2014", 
            "pmid": "24219866"
        }, 
        {
            "title": "An overview of the MAGE gene family with the identification of all human members of the family.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/11454705", 
            "journal": "Cancer research", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093391.1", 
                    "id": "NP_001093391.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Chomez P, De Backer O, Bertrand M, De Plaen E, Boon T, Lucas S", 
            "date": "2001", 
            "pmid": "11454705"
        }
    ], 
    "glycosylation": [], 
    "mutation": [
        {
            "start_pos": 83, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.3", 
            "annotation": "Filters passed (1/5): patient freq. (1.3%).", 
            "sequence_org": "S", 
            "disease": {
                "doid": "1319", 
                "url": "http://disease-ontology.org/term/DOID:1319", 
                "icd10": "", 
                "name": "Brain cancer"
            }, 
            "sequence_mut": "Y", 
            "subjects_tested": "78", 
            "end_pos": 83, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 67, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.5", 
            "annotation": "Filters passed (1/5): patient freq. (1.5%).", 
            "sequence_org": "S", 
            "disease": {
                "doid": "1324", 
                "url": "http://disease-ontology.org/term/DOID:1324", 
                "icd10": "", 
                "name": "Lung cancer"
            }, 
            "sequence_mut": "N", 
            "subjects_tested": "66", 
            "end_pos": 67, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 190, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "Y", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "H", 
            "subjects_tested": "50", 
            "end_pos": 190, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 107, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.6", 
            "annotation": "Filters passed (1/5): patient freq. (1.6%).", 
            "sequence_org": "N", 
            "disease": {
                "doid": "2531", 
                "url": "http://disease-ontology.org/term/DOID:2531", 
                "icd10": "", 
                "name": "Hematologic cancer"
            }, 
            "sequence_mut": "Y", 
            "subjects_tested": "63", 
            "end_pos": 107, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 232, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.1", 
            "annotation": "Filters passed (1/5): patient freq. (2.1%).", 
            "sequence_org": "T", 
            "disease": {
                "doid": "2531", 
                "url": "http://disease-ontology.org/term/DOID:2531", 
                "icd10": "", 
                "name": "Hematologic cancer"
            }, 
            "sequence_mut": "M", 
            "subjects_tested": "48", 
            "end_pos": 232, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 272, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "0.2", 
            "annotation": "Filters passed (1/5): num. of cancers (3).", 
            "sequence_org": "R", 
            "disease": {
                "doid": "363", 
                "url": "http://disease-ontology.org/term/DOID:363", 
                "icd10": "", 
                "name": "Uterine cancer"
            }, 
            "sequence_mut": "Q", 
            "subjects_tested": "558", 
            "end_pos": 272, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 272, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "0.3", 
            "annotation": "Filters passed (1/5): num. of cancers (3).", 
            "sequence_org": "R", 
            "disease": {
                "doid": "4362", 
                "url": "http://disease-ontology.org/term/DOID:4362", 
                "icd10": "", 
                "name": "Cervical cancer"
            }, 
            "sequence_mut": "Q", 
            "subjects_tested": "350", 
            "end_pos": 272, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 272, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "0.1", 
            "annotation": "Filters passed (1/5): num. of cancers (3).", 
            "sequence_org": "R", 
            "disease": {
                "doid": "4159", 
                "url": "http://disease-ontology.org/term/DOID:4159", 
                "icd10": "", 
                "name": "Skin cancer"
            }, 
            "sequence_mut": "Q", 
            "subjects_tested": "820", 
            "end_pos": 272, 
            "type": "Point mutation"
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A368#A2A368-1", 
            "isoform_ac": "A2A368-1", 
            "locus": {
                "end_pos": 35802197, 
                "start_pos": 35803168, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000399988", 
                        "id": "ENST00000399988", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000382870", 
                        "id": "ENSP00000382870", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2A368-1|MAGBG_HUMAN Isoform 1 of Melanoma-associated antigen B16  OS=Homo sapiens OX=9606 GN=MAGEB16 PE=4 SV=2 CANONICAL=A2A368-1", 
                "length": 324, 
                "sequence": "MSQDQESPRCTHDQHLQTFSETQSLEVAQVSKALEKTLLSSSHPLVPGKLKEAPAAKAESPLEVPQSFCSSSIAVTTTSSSESDEASSNQEEEDSPSSSEDTSDPRNVPADALDQKVAFLVNFMLHKCQMKKPITKADMLKIIIKDDESHFSEILLRASEHLEMIFGLDVVEVDPTTHCYGLFIKLGLTYDGMLSGEKGVPKTGLLIIVLGVIFMKGNRATEEEVWEVLNLTGVYSGKKHFIFGEPRMLITKDFVKEKYLEYQQVANSDPARYEFLWGPRAKAETSKMKVLEFVAKVHGSYPHSFPSQYAEALKEEEERARARI"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A368#A0A0A0MSA3-1", 
            "isoform_ac": "A0A0A0MSA3-1", 
            "locus": {
                "end_pos": 35800539, 
                "start_pos": 35803168, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000399992", 
                        "id": "ENST00000399992", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000382874", 
                        "id": "ENSP00000382874", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0A0MSA3-1|MAGBG_HUMAN Computationally mapped isoform of Melanoma-associated antigen B16  OS=Homo sapiens OX=9606 GN=MAGEB16 PE=4 SV=1 CANONICAL=A2A368-1", 
                "length": 356, 
                "sequence": "MGTEAQPVVKAVILHCLPSCPHSCLLPPTRVIMSQDQESPRCTHDQHLQTFSETQSLEVAQVSKALEKTLLSSSHPLVPGKLKEAPAAKAESPLEVPQSFCSSSIAVTTTSSSESDEASSNQEEEDSPSSSEDTSDPRNVPADALDQKVAFLVNFMLHKCQMKKPITKADMLKIIIKDDESHFSEILLRASEHLEMIFGLDVVEVDPTTHCYGLFIKLGLTYDGMLSGEKGVPKTGLLIIVLGVIFMKGNRATEEEVWEVLNLTGVYSGKKHFIFGEPRMLITKDFVKEKYLEYQQVANSDPARYEFLWGPRAKAETSKMKVLEFVAKVHGSYPHSFPSQYAEALKEEEERARARI"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:139604", 
            "resource": "KEGG Pathway", 
            "id": "hsa:139604", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093391.1", 
            "annotation": "The testis-specific expression of MAGEB16 and Mageb16 is regulated by the methylation status of their promoter regions.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093391.1", 
                    "id": "NP_001093391.1", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q6AY37-1", 
            "protein_name": "Melanoma-associated antigen B16; MAGE-B16 antigen.", 
            "sequence": {
                "length": 360, 
                "sequence": "MSQKNPEYAADHDHTREEMQNLQVAPASSDVEEPCSSSHLMASSLKGHTSEETQVPEDMEEPCSSSQLLTASNQEDPAYETPSTSRGLQHPYVSSSESAKGLGNKEMQGNSVIPPDQPDLPVMTIDGKVNFLVNYMLYKYQVKEMMSMNDIMTLIVREDEHHFHEILMRASERMEMVFGLEVREVDPVNHFYALFIKLGLTYDGMRADEYSFPKTGLLILILGVVFMKGNRATEEEIWEVLNPMGIYAGMNHFIFGDPRELLTDDFVREQYLAYQPIANSDPIQYEYVWGPRAKAETSKMKVLEFVAKVHGSDPTVFPSQYEEALIEEEERTLAMILEQAGPSSASGESSSDMGSNVPHI"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/72569", 
                    "id": "72569", 
                    "database": "MGI"
                }
            ], 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q9CWV4-1", 
            "protein_name": "Melanoma-associated antigen B16; MAGE-B16 antigen.", 
            "sequence": {
                "length": 363, 
                "sequence": "MSQSSEECAADQGQTCEETQKLQVAAASIDVEEPCSSPHLMATSLKDQTSEETQVSKDVEEPCSSSQLLMASDQDDSEDETASTSSDLQHPYDSSSESTEDLDDQEVQGSPVIPPDQSDSTDLPVMTVDGKVDFLVNYMLYKYQVKEVMSMNDIMTLIVREDEDRFHEILMRASERMEMVFGLDVKEVDPINHCYALFIKLGLTYDGMRNDEYSFPKTGLLILILGVVFMKGNRATEEEIWEVLNPMGIYAGMTHFMFGDPRELITDEFVREQYLEYQPIANSDPIQYEYVWGLRAKAETSKMRVLEFVAKVHGSDPTVFLSQYEEALIEEEERTLTMLLEHADSSSTSGESSSDTSSNFSQV"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/72569", 
                    "id": "72569", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093391.1", 
        "ac": "NP_001093391.1", 
        "name": "melanoma-associated antigen B16; melanoma antigen family B, 16 (pseudogene); MAGE-B16 antigen; melanoma antigen family B16.", 
        "summary": ""
    }, 
    "go_annotation": {}, 
    "site_annotation": [
        {
            "end_pos": 232, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 230
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093391.1", 
            "id": "NP_001093391.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=21188", 
            "id": "21188", 
            "database": "HGNC"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A2A368", 
            "id": "A2A368", 
            "database": "PHAROS"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A2A368", 
            "id": "NX_A2A368", 
            "database": "neXtProt"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=MAGEB16", 
            "id": "MAGEB16", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:139604", 
            "id": "hsa:139604", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
            "id": "ENSG00000189023", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR021072", 
            "id": "IPR021072", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002190", 
            "id": "IPR002190", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR037445", 
            "id": "IPR037445", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041898", 
            "id": "IPR041898", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041899", 
            "id": "IPR041899", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF01454", 
            "id": "PF01454", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF12440", 
            "id": "PF12440", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736", 
            "id": "PTHR11736", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2A368", 
            "id": "PR_A2A368", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A2A368*", 
            "id": "A2A368", 
            "database": "IntAct"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/139604", 
            "id": "139604", 
            "database": "GeneID"
        }
    ], 
    "expression_disease": [
        {
            "trend": "Up", 
            "disease": {
                "doid": "11054", 
                "url": "http://disease-ontology.org/term/DOID:11054", 
                "icd10": "", 
                "name": "DOID:11054 / Urinary bladder cancer [UBC]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "3571", 
                "url": "http://disease-ontology.org/term/DOID:3571", 
                "icd10": "", 
                "name": "DOID:3571 / Liver cancer [Livca]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Up", 
            "disease": {
                "doid": "5041", 
                "url": "http://disease-ontology.org/term/DOID:5041", 
                "icd10": "", 
                "name": "DOID:5041 / Esophageal cancer [EC]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Up", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "DOID:1781 / Thyroid cancer [Thyca]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Up", 
            "disease": {
                "doid": "3910", 
                "url": "http://disease-ontology.org/term/DOID:3910", 
                "icd10": "", 
                "name": "DOID:3910 / Lung adenocarcinoma"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Up", 
            "disease": {
                "doid": "10283", 
                "url": "http://disease-ontology.org/term/DOID:10283", 
                "icd10": "", 
                "name": "DOID:10283 / Prostate cancer [PCa]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Up", 
            "disease": {
                "doid": "3907", 
                "url": "http://disease-ontology.org/term/DOID:3907", 
                "icd10": "", 
                "name": "DOID:3907 / Lung squamous cell carcinoma"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2A368", 
                    "id": "A2A368", 
                    "database": "BioXpress"
                }
            ]
        }
    ], 
    "uniprot_ac": "A2A368", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 36178.0, 
        "chemical_mass": 36178.0
    }, 
    "expression_tissue": [
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0009853", 
                "uberon": "0009853", 
                "name": "Body of uterus"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000458", 
                "uberon": "0000458", 
                "name": "Endocervix"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000948", 
                "uberon": "0000948", 
                "name": "Heart"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000473", 
                "uberon": "0000473", 
                "name": "Testis"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002369", 
                "uberon": "0002369", 
                "name": "Adrenal gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000992", 
                "uberon": "0000992", 
                "name": "Ovary"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000996", 
                "uberon": "0000996", 
                "name": "Vagina"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001155", 
                "uberon": "0001155", 
                "name": "Colon"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001987", 
                "uberon": "0001987", 
                "name": "Placenta"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000955", 
                "uberon": "0000955", 
                "name": "Brain"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001160", 
                "uberon": "0001160", 
                "name": "Fundus of stomach"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001150", 
                "uberon": "0001150", 
                "name": "Body of pancreas"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002048", 
                "uberon": "0002048", 
                "name": "Lung"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000007", 
                "uberon": "0000007", 
                "name": "Pituitary gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002107", 
                "uberon": "0002107", 
                "name": "Liver"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002046", 
                "uberon": "0002046", 
                "name": "Thyroid gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000178", 
                "uberon": "0000178", 
                "name": "Blood"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001043", 
                "uberon": "0001043", 
                "name": "Esophagus"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002367", 
                "uberon": "0002367", 
                "name": "Prostate gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001161", 
                "uberon": "0001161", 
                "name": "Body of stomach"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001255", 
                "uberon": "0001255", 
                "name": "Urinary bladder"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000189023", 
                    "id": "ENSG00000189023", 
                    "database": "Bgee"
                }
            ]
        }
    ], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A368", 
            "name": "MAGEB16.", 
            "locus": {
                "end_pos": 35803735, 
                "start_pos": 35798342, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000189023", 
                        "id": "ENSG00000189023", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}