{
    "uniprot_canonical_ac": "A1XIQ3-1", 
    "sequence": {
        "header": "tr|A1XIQ3-1|A1XIQ3_RAT Isoform 1 of Nyctalopin  OS=Rattus norvegicus OX=10116 GN=Nyx PE=2 SV=1 CANONICAL=A1XIQ3-1", 
        "length": 476, 
        "sequence": "MLNLLLYAVVFSLPCTRATEACLRACPAACTCSNVERGCSVRCDRAGLQRVPTEFPCEAASIDLDRNGLRILGERAFGTLPSLRCLSLRHNNLSFITPGAFKGLPRLAELRLAHNGELRYLHVRTFAALGRLRRLDLAACRLFSVPERLLAELPALRELTAFDNLFRRVPGALRGLANLTHAHFERSRIEAVASSSLLGMRRLRSLSLQANRVRAVHAGAFGDCVALEHLLLNDNLLASLPAAAFRGLRRLRTLNLGGNALGSVARGWFSDLAELELLYLDRNSITFVEEGAFQNLSGLLALHLNGNRLTVLSWAAFQPGFFLGRLFLFRNPWRCDCHLEWLRDWMEGSGRVADVACASPGSVAGQDLSQVVFERSSDGICVDPDELNFTTFSPGPSPEPVATTVSRFSSLLSKLLAPRAPVEEVANTTWELVNVSLNDSFRSHGVMVMCYKATFLFTSCLWLSLAQYVVLGPQRD"
    }, 
    "uniprot_id": "A1XIQ3_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "nyctalopin precursor"
            ], 
            "uniprotkb": [
                "Nyctalopin", 
                "Nyctalopin (Predicted)"
            ]
        }, 
        "gene": {
            "refseq": [
                "Nyx", 
                "RGD1561300"
            ], 
            "uniprotkb": [
                "Nyx", 
                "Nyx_predicted", 
                "rCG_42945", 
                "RGD1561300"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1XIQ3", 
                    "id": "A1XIQ3", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Nyctalopin; Nyctalopin (Predicted)."
    }, 
    "publication": [
        {
            "title": "A naturally-occurring mutation in Cacna1f in a rat model of congenital stationary night blindness.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/18246026", 
            "journal": "Mol. Vis.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1XIQ3/publications", 
                    "id": "A1XIQ3", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Gu Y., Li L., Liu X., Wang L., Zhang Z., Zhou J., Guo Q., An J., Yao L., Liu N., Ding Z., Yan G.", 
            "date": "2008", 
            "pmid": "18246026"
        }, 
        {
            "title": "Contribution of Kir4.1 to the mouse electroretinogram.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/15359216", 
            "journal": "Molecular vision", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094437.1", 
                    "id": "NP_001094437.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Wu J, Marmorstein AD, Kofuji P, Peachey NS", 
            "date": "2004", 
            "pmid": "15359216"
        }, 
        {
            "title": "Identification of the gene and the mutation responsible for the mouse nob phenotype.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/12506099", 
            "journal": "Investigative ophthalmology & visual science", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094437.1", 
                    "id": "NP_001094437.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Gregg RG, Mukhopadhyay S, Candille SI, Ball SL, Pardue MT, McCall MA, Peachey NS", 
            "date": "2003", 
            "pmid": "12506099"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A1XIQ3#A1XIQ3-1", 
            "isoform_ac": "A1XIQ3-1", 
            "locus": {
                "end_pos": 10197889, 
                "start_pos": 10218078, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000013382", 
                        "id": "ENSRNOT00000013382", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000013382", 
                        "id": "ENSRNOP00000013382", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A1XIQ3-1|A1XIQ3_RAT Isoform 1 of Nyctalopin  OS=Rattus norvegicus OX=10116 GN=Nyx PE=2 SV=1 CANONICAL=A1XIQ3-1", 
                "length": 476, 
                "sequence": "MLNLLLYAVVFSLPCTRATEACLRACPAACTCSNVERGCSVRCDRAGLQRVPTEFPCEAASIDLDRNGLRILGERAFGTLPSLRCLSLRHNNLSFITPGAFKGLPRLAELRLAHNGELRYLHVRTFAALGRLRRLDLAACRLFSVPERLLAELPALRELTAFDNLFRRVPGALRGLANLTHAHFERSRIEAVASSSLLGMRRLRSLSLQANRVRAVHAGAFGDCVALEHLLLNDNLLASLPAAAFRGLRRLRTLNLGGNALGSVARGWFSDLAELELLYLDRNSITFVEEGAFQNLSGLLALHLNGNRLTVLSWAAFQPGFFLGRLFLFRNPWRCDCHLEWLRDWMEGSGRVADVACASPGSVAGQDLSQVVFERSSDGICVDPDELNFTTFSPGPSPEPVATTVSRFSSLLSKLLAPRAPVEEVANTTWELVNVSLNDSFRSHGVMVMCYKATFLFTSCLWLSLAQYVVLGPQRD"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:302516", 
            "resource": "KEGG Pathway", 
            "id": "rno:302516", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "P83503-1", 
            "protein_name": "Nyctalopin.", 
            "sequence": {
                "length": 476, 
                "sequence": "MLILLLHAVVFSLPYTRATEACLRACPAACTCSHVERGCSVRCDRAGLQRVPQEFPCEAASIDLDRNGLRILGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGELRYLHVRTFAALGRLRRLDLAACRLFSVPERLLAELPALRELTAFDNLFRRVPGALRGLANLTHAHFERSRIEAVASGSLLGMRRLRSLSLQANRVRAVHAGAFGDCGALEDLLLNDNLLATLPAAAFRGLRRLRTLNLGGNALGSVARAWFSDLAELELLYLDRNSITFVEEGAFQNLSGLLALHLNGNRLTVLSWAAFQPGFFLGRLFLFRNPWRCDCQLEWLRDWMEGSGRVADVACASPGSVAGQDLSQVVFERSSDGLCVDPDELNFTTSSPGPSPEPVATTVSRFSSLLSKLLAPRAPVEEVANTTWELVNVSLNDSFRSHAVMVFCYKATFLFTSCVLLSLAQYVVVGLQRE"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A1XIQ3/", 
                    "id": "A1XIQ3", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/11210", 
                    "id": "11210", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q9GZU5-1", 
            "protein_name": "Nyctalopin.", 
            "sequence": {
                "length": 481, 
                "sequence": "MKGRGMLVLLLHAVVLGLPSAWAVGACARACPAACACSTVERGCSVRCDRAGLLRVPAELPCEAVSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWCCDCRLEWLRDWMEGSGRVTDVPCASPGSVAGLDLSQVTFGRSSDGLCVDPEELNLTTSSPGPSPEPAATTVSRFSSLLSKLLAPRVPVEEAANTTGGLANASLSDSLSSRGVGGAGRQPWFLLASCLLPSVAQHVVFGLQMD"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A1XIQ3/", 
                    "id": "A1XIQ3", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/11210", 
                    "id": "11210", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094437.1", 
        "ac": "NP_001094437.1", 
        "name": "nyctalopin precursor.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1XIQ3", 
                                "id": "A1XIQ3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "extracellular space", 
                        "id": "GO:0005615"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1XIQ3", 
                                "id": "A1XIQ3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "extracellular matrix", 
                        "id": "GO:0031012"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1XIQ3", 
                                "id": "A1XIQ3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "visual perception", 
                        "id": "GO:0007601"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 94, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 92
        }, 
        {
            "end_pos": 180, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 178
        }, 
        {
            "end_pos": 297, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 295
        }, 
        {
            "end_pos": 390, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 388
        }, 
        {
            "end_pos": 429, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 427
        }, 
        {
            "end_pos": 436, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 434
        }, 
        {
            "end_pos": 440, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 438
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094437.1", 
            "id": "NP_001094437.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:302516", 
            "id": "rno:302516", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000009646", 
            "id": "ENSRNOG00000009646", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/HNEYIRY/", 
            "id": "HNEYIRY", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", 
            "id": "IPR000483", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", 
            "id": "IPR001611", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", 
            "id": "IPR003591", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", 
            "id": "IPR032675", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", 
            "id": "IPR000372", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF13855", 
            "id": "PF13855", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/302516", 
            "id": "302516", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1561300", 
            "id": "1561300", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A1XIQ3", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 52471.0, 
        "chemical_mass": 52471.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A1XIQ3", 
            "name": "Nyx; Nyx_predicted; rCG_42945; RGD1561300.", 
            "locus": {
                "end_pos": 10197547, 
                "start_pos": 10218583, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000009646", 
                        "id": "ENSRNOG00000009646", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}