{ "uniprot_canonical_ac": "A1L1L7-1", "sequence": { "header": "sp|A1L1L7-1|ZN426_RAT Isoform 1 of Zinc finger protein 426 OS=Rattus norvegicus OX=10116 GN=Znf426 PE=2 SV=1 CANONICAL=A1L1L7-1", "length": 553, "sequence": "MAAPDSLSHGPSGDSVCLQEEKVSAEMMLVDCLTNYQELVSFDDVIVDFTQEEWTSLNPDQRTLYREVMLENYKNLATVGYQLIKPSVISWLEQEEFSTGQKIVFPEWKIQLETQCSASQQELLRGNISNGMQTQTGSDTGRGLCDGTQYGDFFSELSPLRTVMKTRPAQDNYDSSQCRKDFLMLQRKKCAGEKLSEFNQSEETGAIPGKAYQKMATQEKCFECSDCGKSFMNQSHLQTHQRTHSGDKLYELNECGRSFINSRLAVLIETLNAKKPHRCKECGKGYRYPAYLNIHMRTHTGEKPYECKECGKAFNYSNSFQIHGRTHTGEKPYVCNQCGKAFTQHSGLSIHVRSHNGDKPYACKECGKAFLTSSRLIQHIRTHTGEKPFVCVKCGKAFAISSNLNGHLKMHAEEKTCECKICGKAFGYLSCLNNHMRTHNAKKSYTCKECGKAFNYSTHLKIHMRIHTGEKPYECKQCGKAFSHSTSFQIHERTHTGEKPYECKECGKAFICPSSFRIHEISHTHTEEKPYKCQQCGKAYSHPRSLRRHERIH" }, "uniprot_id": "ZN426_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "zinc finger protein 426" ], "uniprotkb": [ "Zinc finger protein 426" ] }, "gene": { "refseq": [ "Zfp426", "Znf426" ], "uniprotkb": [ "Znf426", "Zfp426" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L1L7", "id": "A1L1L7", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Zinc finger protein 426." }, "publication": [ { "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/12477932", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073412.1", "id": "NP_001073412.1", "database": "RefSeq" } ], "authors": "Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA", "date": "2002", "pmid": "12477932" } ], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A1L1L7#A1L1L7-1", "isoform_ac": "A1L1L7-1", "locus": { "end_pos": 21478386, "start_pos": 21492801, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000077465", "id": "ENSRNOT00000077465", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000069966", "id": "ENSRNOP00000069966", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A1L1L7-1|ZN426_RAT Isoform 1 of Zinc finger protein 426 OS=Rattus norvegicus OX=10116 GN=Znf426 PE=2 SV=1 CANONICAL=A1L1L7-1", "length": 553, "sequence": "MAAPDSLSHGPSGDSVCLQEEKVSAEMMLVDCLTNYQELVSFDDVIVDFTQEEWTSLNPDQRTLYREVMLENYKNLATVGYQLIKPSVISWLEQEEFSTGQKIVFPEWKIQLETQCSASQQELLRGNISNGMQTQTGSDTGRGLCDGTQYGDFFSELSPLRTVMKTRPAQDNYDSSQCRKDFLMLQRKKCAGEKLSEFNQSEETGAIPGKAYQKMATQEKCFECSDCGKSFMNQSHLQTHQRTHSGDKLYELNECGRSFINSRLAVLIETLNAKKPHRCKECGKGYRYPAYLNIHMRTHTGEKPYECKECGKAFNYSNSFQIHGRTHTGEKPYVCNQCGKAFTQHSGLSIHVRSHNGDKPYACKECGKAFLTSSRLIQHIRTHTGEKPFVCVKCGKAFAISSNLNGHLKMHAEEKTCECKICGKAFGYLSCLNNHMRTHNAKKSYTCKECGKAFNYSTHLKIHMRIHTGEKPYECKQCGKAFSHSTSFQIHERTHTGEKPYECKECGKAFICPSSFRIHEISHTHTEEKPYKCQQCGKAYSHPRSLRRHERIH" } }, { "url": "https://www.uniprot.org/uniprot/A1L1L7#A0A0G2JW15-1", "isoform_ac": "A0A0G2JW15-1", "locus": { "end_pos": 21515761, "start_pos": 21523540, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000085060", "id": "ENSRNOT00000085060", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000069702", "id": "ENSRNOP00000069702", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2JW15-1|ZN426_RAT Computationally mapped isoform of Zinc finger protein 426 OS=Rattus norvegicus OX=10116 GN=Znf426 PE=2 SV=1 CANONICAL=A1L1L7-1", "length": 604, "sequence": "MAAIDLSHGLLPREPIYVYEANIEVEGTVTDNQANCYQDSVTFDDVAVEFTPDEWTLLDLTQKNLYREVMLENYENLTSVGCQFFIPSLTPWLKQEELGVAESALPQQLELQPTIDDSELENYFRMQSSSATEMVGDSSLQEQSGNHSEGDLRDSKPCGNVLGEQLCLNTEVSTQSQGYSSECNWYGKDILSLLKETSTGQNVSELNQCGKLFSLTPNIMYPSTSTNEKPFECTDCETAFFNQSYFQPDMRPHNGGEPYDWSKFGNGFIHPTSLAMHLPILNARNPYKFEECGKDFQYFACLNNPMGMCTGEKFCDCKECWKAFTVSSHLTQYVSIHTEEKSKVCKICGKSFANYSRLSAHVKTHNEEKPFVCKECGKAFKNMSYLNDHVRIHTGIKSYKCMECGKAFLRWSGLTEHIRVHTGEKPYECKECGKTFSRSTQLTEHIRTHTGIKPYECKECGKAFTQYSGLATHVRIHSGEKPFACKECGKAFTRTSGLIHHVRTHTGEKPFECVHCGKTFITSSHRTKHLKIHSGEKPFVCNICGKAFIYSTSLNIHMRTHTGEKPYICKQCGKAFAVYSRLRKHSRVHTEEKPYQCEGVGVAT" } }, { "url": "https://www.uniprot.org/uniprot/A1L1L7#A0A0H2UHW3-1", "isoform_ac": "A0A0H2UHW3-1", "locus": { "end_pos": 21478386, "start_pos": 21481735, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000038069", "id": "ENSRNOT00000038069", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000038875", "id": "ENSRNOP00000038875", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0H2UHW3-1|ZN426_RAT Computationally mapped isoform of Zinc finger protein 426 OS=Rattus norvegicus OX=10116 GN=Znf426 PE=2 SV=1 CANONICAL=A1L1L7-1", "length": 478, "sequence": "TLYTGYQLIKPSVISWLEQEEFSTGQKIVFPEWKIQLETQCSASQQELLRGNISNGMQTQTGSDTGRGLCDGTQYGDFFSELSPLRTVMKTRPAQDNYDSSQCRKDFLMLQRKKCAGEKLSEFNQSEETGAIPGKAYQKMATQEKCFECSDCGKSFMNQSHLQTHQRTHSGDKLYELNECGRSFINSRLAVLIETLNAKKPHRCKECGKGYRYPAYLNIHMRTHTGEKPYECKECGKAFNYSNSFQIHGRTHTGEKPYVCNQCGKAFTQHSGLSIHVRSHNGDKPYACKECGKAFLTSSRLIQHIRTHTGEKPFVCVKCGKAFAISSNLNGHLKMHAEEKTCECKICGKAFGYLSCLNNHMRTHNAKKSYTCKECGKAFNYSTHLKIHMRIHTGEKPYECKQCGKAFSHSTSFQIHERTHTGEKPYECKECGKAFICPSSFRIHEISHTHTEEKPYKCQQCGKAYSHPRSLRRHERIH" } }, { "url": "https://www.uniprot.org/uniprot/A1L1L7#F1MAL0-1", "isoform_ac": "F1MAL0-1", "locus": { "end_pos": 21515761, "start_pos": 21518816, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000042903", "id": "ENSRNOT00000042903", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000042506", "id": "ENSRNOP00000042506", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F1MAL0-1|ZN426_RAT Computationally mapped isoform of Zinc finger protein 426 OS=Rattus norvegicus OX=10116 GN=Znf426 PE=2 SV=2 CANONICAL=A1L1L7-1", "length": 531, "sequence": "MYVSVYAGCQFFIPSLTPWLKQEELGVAESALPQQLELQPTIDDSELENYFRMQSSSATEMVGDSSLQEQSGNHSEGDLRDSKPCGNVLGEQLCLNTEVSTQSQGYSSECNWYGKDILSLLKETSTGQNVSELNQCGKLFSLTPNIMYPSTSTNEKPFECTDCETAFFNQSYFQPDMRPHNGGEPYDWSKFGNGFIHPTSLAMHLPILNARNPYKFEECGKDFQYFACLNNPMGMCTGEKFCDCKECWKAFTVSSHLTQYVSIHTEEKSKVCKICGKSFANYSRLSAHVKTHNEEKPFVCKECGKAFKNMSYLNDHVRIHTGIKSYKCMECGKAFLRWSGLTEHIRVHTGEKPYECKECGKTFSRSTQLTEHIRTHTGIKPYECKECGKAFTQYSGLATHVRIHSGEKPFACKECGKAFTRTSGLIHHVRTHTGEKPFECVHCGKTFITSSHRTKHLKIHSGEKPFVCNICGKAFIYSTSLNIHMRTHTGEKPYICKQCGKAFAVYSRLRKHSRVHTEEKPYQCEGVGVAT" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/www_bget?rno:690895", "resource": "KEGG Pathway", "id": "rno:690895", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-212436", "resource": "Reactome", "id": "R-RNO-212436", "name": "Generic Transcription Pathway" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A1L1L7#function", "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L1L7#function", "id": "A1L1L7", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q9BUY5-1", "protein_name": "Zinc finger protein 426.", "sequence": { "length": 554, "sequence": "MAAADLSHGHYLSGDPVCLHEEKTPAGRIVADCLTDCYQDSVTFDDVAVDFTQEEWTLLDSTQRSLYSDVMLENYKNLATVGGQIIKPSLISWLEQEESRTVQGGVLQGWEMRLETQWSILQQDFLRGQTSIGIQLEGKHNGRELCDCEQCGEVFSEHSCLKTHVRTQSTGNTHDCNQYGKDFLTLCEKTSTGEKLSEFNQSEKIFSLTPNIVYQRTSTQEKSFECSHCGKSFINESYLQAHMRTHNGEKLYEWRNYGPGFIDSTSLSVLIETLNAKKPYKCKECGKGYRYPAYLSIHMRTHTGEKPYECKECGKAFNYSNSFQIHGRTHTGEKPYVCKECGKAFTQYSGLSMHVRSHSGDKPYECKECGKSFLTSSRLIQHIRTHTGEKPFVCVECGKAFAVSSNLSGHLRTHTEEKACECKICGKVFGYPSCLNNHMRTHSAQKPYTCKECGKAFNYSTHLKIHMRIHTGEKPYECKQCGKAFSHSSSFQIHERTHTGEKPYECKECGKAFTCSSSFRIHEKTHTEEKPYKCQQCGKAYSHPRSLRRHEQIH" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A1L1L7/", "id": "A1L1L7", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/23435", "id": "23435", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "Q8R1D1-1", "protein_name": "Zinc finger protein 426.", "sequence": { "length": 550, "sequence": "MAAPASSHGPSEDSGCLQERKIAAEMMLVDCLTDDQELVSFEDVIVDFTQEEWSSLNPDQRNLYRDVMLENYQNLATVGYQLIKPSLISWLEQEEFSKGQKIVFPEWKLQLETKCSAFQQEFLRGNISSRMQMQTGINRGRELCDGTQYGDFFSELSPLRTDMKTQPAQDNYGCSQYRKDFLMLQRKNCAGEKLSEFSQSEETGMTPVKEKIDTQEKGFECSDCGKSFMSQSHLQTHQRTHSGDKLYEWNECGRSFINSRLAVLIETLNAKKPHRCKECGKGYRYPAYLNIHMRTHTGEKPYECKECGKAFNYSNSFQIHGRTHTGEKPYVCSQCGKAFTQHSGLSIHVRSHTGDKPYGCKECGKAFLTSSRLIQHIRTHTGEKPFVCVKCGKAFAISSNLNGHLKLHAEEKTCECKICGKAFGYLSCLNNHMRTHNAKKSYTCKECGKAFNYSTHLKIHMRIHTGEKPYECKQCGKAFSHSTSFQIHERTHTGEKPYECKECGKAFICPSSFRIHEISHTHTEEKPYKCQQCGKAYSHPRSLRRHERIH" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/23435", "id": "23435", "database": "MGI" } ], "organism": "Mus musculus", "tax_id": 10090 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073412.1", "ac": "NP_001073412.1", "name": "zinc finger protein 426.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L1L7", "id": "A1L1L7", "database": "UniProtKB" } ], "name": "DNA binding", "id": "GO:0003677" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L1L7", "id": "A1L1L7", "database": "UniProtKB" } ], "name": "metal ion binding", "id": "GO:0046872" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L1L7", "id": "A1L1L7", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" } ], "total": 1, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L1L7", "id": "A1L1L7", "database": "UniProtKB" } ], "name": "regulation of transcription, DNA-templated", "id": "GO:0006355" } ], "total": 1, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 129, "annotation": "n_glycosylation_sequon", "start_pos": 127 }, { "end_pos": 201, "annotation": "n_glycosylation_sequon", "start_pos": 199 }, { "end_pos": 235, "annotation": "n_glycosylation_sequon", "start_pos": 233 }, { "end_pos": 317, "annotation": "n_glycosylation_sequon", "start_pos": 315 }, { "end_pos": 457, "annotation": "n_glycosylation_sequon", "start_pos": 455 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073412.1", "id": "NP_001073412.1", "database": "RefSeq" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-212436", "id": "R-RNO-212436", "database": "Reactome" }, { "url": "https://www.genome.jp/dbget-bin/www_bget?rno:690895", "id": "rno:690895", "database": "KEGG Pathway" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000033624", "id": "ENSRNOG00000033624", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/WEMQLEA/", "id": "WEMQLEA", "database": "OMA" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "id": "cd07765", "database": "CDD" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "id": "IPR013087", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "id": "IPR036236", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "id": "IPR001909", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "id": "IPR036051", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF01352", "id": "PF01352", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00096", "id": "PF00096", "database": "Pfam" }, { "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A1L1L7", "id": "PR_A1L1L7", "database": "PRO" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/690895", "id": "690895", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1308643", "id": "1308643", "database": "RGD" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1308643", "id": "1308643", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A1L1L7", "disease": [], "mass": { "monoisotopic_mass": 63005.0, "chemical_mass": 63005.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A1L1L7", "name": "Znf426; Zfp426.", "locus": { "end_pos": 0, "start_pos": 0, "chromosome": "0", "evidence": [] } } ] }