{ "uniprot_canonical_ac": "A1L0T0-1", "sequence": { "header": "sp|A1L0T0-1|ILVBL_HUMAN Isoform 1 of Acetolactate synthase-like protein OS=Homo sapiens OX=9606 GN=ILVBL PE=1 SV=2 CANONICAL=A1L0T0-1", "length": 632, "sequence": "METPAAAAPAGSLFPSFLLLACGTLVAALLGAAHRLGLFYQLLHKVDKASVRHGGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKRPLMVLGSQALLTPTSADKLRAAVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTVCDFRLSYGRVLSHSSKIIIVNRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQGQTWAPDWVEELREADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCRPDAEVWCLFGDGAFGYSLIEFDTFVRHKIPVMALVGNDAGWTQISREQVPSLGSNVACGLAYTDYHKAAMGLGARGLLLSRENEDQVVKVLHDAQQQCRDGHPVVVNILIGRTDFRDGSIAV" }, "uniprot_id": "ILVBL_HUMAN", "enzyme_annotation": [ { "ec": "2.2.1.-", "activity": "" } ], "synonyms": { "protein": { "refseq": [ "acetolactate synthase-like protein", "acetolactate synthase homolog; ilvB-like protein; ilvB (bacterial acetolactate synthase)-like; 2-hydroxyacyl-CoA lyase 1 like" ], "uniprotkb": [ "Acetolactate synthase-like protein", "2.2.1.-", "IlvB-like protein" ] }, "gene": { "refseq": [ "ILVBL", "209L8", "AHAS", "HACL1L", "ILV2H" ], "uniprotkb": [ "ILVBL", "AHAS", "209L8", "HACL1L", "ILV2H" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L0T0", "id": "A1L0T0", "database": "UniProtKB" } ], "name": "Homo sapiens", "taxid": 9606 } ], "recommendedname": { "full": "Acetolactate synthase-like protein; 2.2.1.-; IlvB-like protein." }, "publication": [ { "title": "Association analysis of ILVBL gene polymorphisms with aspirin-exacerbated respiratory disease in asthma.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/29246216", "journal": "BMC pulmonary medicine", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_006835.2", "id": "NP_006835.2", "database": "RefSeq" } ], "authors": "Chang HS, Park JS, Lee HS, Lyu J, Son JH, Choi IS, Shin HD, Park CS", "date": "2017", "pmid": "29246216" }, { "title": "A human homolog of bacterial acetolactate synthase genes maps within the CADASIL critical region.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/8954801", "journal": "Genomics", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L0T0/publications", "id": "A1L0T0", "database": "UniProtKB" } ], "authors": "Cruaud C., Tournier-Lasserve E., Bousser M.G., Ducros A., Joutel A., Vahedi K., Alamowitch S., Chabriat H., Domenga V., Marechal E.", "date": "1996", "pmid": "8954801" } ], "glycosylation": [], "mutation": [ { "start_pos": 530, "subjects_positive": "3", "evidence": [ { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1L0T0", "id": "A1L0T0", "database": "BioMuta" } ], "frequency": "0.5", "annotation": "Filters passed (1/5): num. of cancers (4). In dbSNP: rs1289847615.", "sequence_org": "E", "disease": { "doid": "363", "url": "http://disease-ontology.org/term/DOID:363", "icd10": "", "name": "Uterine cancer" }, "sequence_mut": "K", "subjects_tested": "558", "end_pos": 530, "type": "Point mutation" }, { "start_pos": 530, "subjects_positive": "1", "evidence": [ { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1L0T0", "id": "A1L0T0", "database": "BioMuta" } ], "frequency": "0.1", "annotation": "Filters passed (1/5): num. of cancers (4). In dbSNP: rs1289847615.", "sequence_org": "E", "disease": { "doid": "10534", "url": "http://disease-ontology.org/term/DOID:10534", "icd10": "", "name": "Stomach cancer" }, "sequence_mut": "K", "subjects_tested": "1044", "end_pos": 530, "type": "Point mutation" }, { "start_pos": 530, "subjects_positive": "1", "evidence": [ { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1L0T0", "id": "A1L0T0", "database": "BioMuta" } ], "frequency": "0.1", "annotation": "Filters passed (1/5): num. of cancers (4). In dbSNP: rs1289847615.", "sequence_org": "E", "disease": { "doid": "4159", "url": "http://disease-ontology.org/term/DOID:4159", "icd10": "", "name": "Skin cancer" }, "sequence_mut": "K", "subjects_tested": "820", "end_pos": 530, "type": "Point mutation" }, { "start_pos": 620, "subjects_positive": "1", "evidence": [ { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1L0T0", "id": "A1L0T0", "database": "BioMuta" } ], "frequency": "1.1", "annotation": "Filters passed (1/5): patient freq. (1.1%).", "sequence_org": "I", "disease": { "doid": "9256", "url": "http://disease-ontology.org/term/DOID:9256", "icd10": "", "name": "Colorectal cancer" }, "sequence_mut": "S", "subjects_tested": "94", "end_pos": 620, "type": "Point mutation" }, { "start_pos": 530, "subjects_positive": "1", "evidence": [ { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1L0T0", "id": "A1L0T0", "database": "BioMuta" } ], "frequency": "0.1", "annotation": "Filters passed (1/5): num. of cancers (4). In dbSNP: rs1289847615.", "sequence_org": "E", "disease": { "doid": "1612", "url": "http://disease-ontology.org/term/DOID:1612", "icd10": "", "name": "Breast cancer" }, "sequence_mut": "K", "subjects_tested": "1144", "end_pos": 530, "type": "Point mutation" } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A1L0T0#A1L0T0-1", "isoform_ac": "A1L0T0-1", "locus": { "end_pos": 15115255, "start_pos": 15125059, "chromosome": "19", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000263383", "id": "ENST00000263383", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000263383", "id": "ENSP00000263383", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A1L0T0-1|ILVBL_HUMAN Isoform 1 of Acetolactate synthase-like protein OS=Homo sapiens OX=9606 GN=ILVBL PE=1 SV=2 CANONICAL=A1L0T0-1", "length": 632, "sequence": "METPAAAAPAGSLFPSFLLLACGTLVAALLGAAHRLGLFYQLLHKVDKASVRHGGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKRPLMVLGSQALLTPTSADKLRAAVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTVCDFRLSYGRVLSHSSKIIIVNRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQGQTWAPDWVEELREADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCRPDAEVWCLFGDGAFGYSLIEFDTFVRHKIPVMALVGNDAGWTQISREQVPSLGSNVACGLAYTDYHKAAMGLGARGLLLSRENEDQVVKVLHDAQQQCRDGHPVVVNILIGRTDFRDGSIAV" } }, { "url": "https://www.uniprot.org/uniprot/A1L0T0#E9PNL1-1", "isoform_ac": "E9PNL1-1", "locus": { "end_pos": 15123223, "start_pos": 15125059, "chromosome": "19", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000533148", "id": "ENST00000533148", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000434734", "id": "ENSP00000434734", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E9PNL1-1|ILVBL_HUMAN Computationally mapped isoform of Acetolactate synthase-like protein OS=Homo sapiens OX=9606 GN=ILVBL PE=1 SV=1 CANONICAL=A1L0T0-1", "length": 52, "sequence": "METPAAAAPAGSLFPSFLLLACGTLVAALLGAAHRLGLFYQLLHKGRWAWRQ" } }, { "url": "https://www.uniprot.org/uniprot/A1L0T0#M0QZX5-1", "isoform_ac": "M0QZX5-1", "locus": { "end_pos": 15116285, "start_pos": 15122757, "chromosome": "19", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000598709", "id": "ENST00000598709", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000470834", "id": "ENSP00000470834", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|M0QZX5-1|ILVBL_HUMAN Computationally mapped isoform of Acetolactate synthase-like protein OS=Homo sapiens OX=9606 GN=ILVBL PE=1 SV=8 CANONICAL=A1L0T0-1", "length": 229, "sequence": "MVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKRPLMVLGSQALLTPTSADKLRAAVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTVCDFRLSYGRVLSHSSKIIIVNRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQGQTWAPDWVEELREADRQKEQTFREKAAMPVAQHLN" } }, { "url": "https://www.uniprot.org/uniprot/A1L0T0#M0R026-1", "isoform_ac": "M0R026-1", "locus": { "end_pos": 15115255, "start_pos": 15123390, "chromosome": "19", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000534378", "id": "ENST00000534378", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000470942", "id": "ENSP00000470942", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|M0R026-1|ILVBL_HUMAN Computationally mapped isoform of Acetolactate synthase-like protein OS=Homo sapiens OX=9606 GN=ILVBL PE=1 SV=1 CANONICAL=A1L0T0-1", "length": 525, "sequence": "MARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKRPLMVLGSQALLTPTSADKLRAAVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTVCDFRLSYGRVLSHSSKIIIVNRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQGQTWAPDWVEELREADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCRPDAEVWCLFGDGAFGYSLIEFDTFVRHKIPVMALVGNDAGWTQISREQVPSLGSNVACGLAYTDYHKAAMGLGARGLLLSRENEDQVVKVLHDAQQQCRDGHPVVVNILIGRTDFRDGSIAV" } }, { "url": "https://www.uniprot.org/uniprot/A1L0T0#E9PL44-1", "isoform_ac": "E9PL44-1", "locus": { "end_pos": 15122998, "start_pos": 15125059, "chromosome": "19", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000533747", "id": "ENST00000533747", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000433355", "id": "ENSP00000433355", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E9PL44-1|ILVBL_HUMAN Computationally mapped isoform of Acetolactate synthase-like protein OS=Homo sapiens OX=9606 GN=ILVBL PE=1 SV=1 CANONICAL=A1L0T0-1", "length": 166, "sequence": "METPAAAAPAGSLFPSFLLLACGTLVAALLGAAHRLGLFYQLLHKVDKASVRHGGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQL" } }, { "url": "https://www.uniprot.org/uniprot/A1L0T0#M0R1B5-1", "isoform_ac": "M0R1B5-1", "locus": { "end_pos": 15119982, "start_pos": 15123390, "chromosome": "19", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000600984", "id": "ENST00000600984", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000471762", "id": "ENSP00000471762", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|M0R1B5-1|ILVBL_HUMAN Computationally mapped isoform of Acetolactate synthase-like protein OS=Homo sapiens OX=9606 GN=ILVBL PE=1 SV=8 CANONICAL=A1L0T0-1", "length": 165, "sequence": "MARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQ" } }, { "url": "https://www.uniprot.org/uniprot/A1L0T0#E9PJS0-1", "isoform_ac": "E9PJS0-1", "locus": { "end_pos": 15120012, "start_pos": 15125059, "chromosome": "19", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000527093", "id": "ENST00000527093", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000435516", "id": "ENSP00000435516", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E9PJS0-1|ILVBL_HUMAN Computationally mapped isoform of Acetolactate synthase-like protein OS=Homo sapiens OX=9606 GN=ILVBL PE=1 SV=1 CANONICAL=A1L0T0-1", "length": 262, "sequence": "METPAAAAPAGSLFPSFLLLACGTLVAALLGAAHRLGLFYQLLHKVDKASVRHGGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLP" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:10994", "resource": "KEGG Pathway", "id": "hsa:10994", "name": "" } ], "function": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_006835.2", "annotation": "To the best of our knowledge, this is the first report of an association between single nucleotide polymorphisms (SNPs) on ILVBL and aspirin-exacerbated respiratory disease (AERD) . SNPs on ILVBL could be promising genetic markers of this condition. Publication Status: Online-Only", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_006835.2", "id": "NP_006835.2", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACG2-1", "protein_name": "IlvB acetolactate synthase-like; IlvB (Bacterial acetolactate synthase)-like (Predicted), isoform CRA_c.", "sequence": { "length": 672, "sequence": "MGAWPCDSMMLARGGLSAEVESCVEEGGFPVGSLINRFFLMETTAAAASAGGFFPSFLLLAFGTLVAAVLGAAHRLGLFYQLMHKVDKTSIRHGGESVAAVLRAHGVRFVFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAVARLTGTVGVAAVTAGPGLTNTVTAVKNAQVAQSPVLLLGGAASTLLQKRGALQAIDQMSLFRPLCKFCASVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPLDVLYPYFMVEKEMIPAQLPKGLMGRVVVWYLQNCLANLFAGAWEPRPEGPLPLDIPQASPQQVQRCVEILSRAKRPLLVLGSQALLPPTPANKLRAAVETLGVPCFLGGMSRGLLGRNHPLHIRQNRSAALKKADVVVLAGAVCDFRLSYGRVLNRKSSIIIVNRNRDDMLLNSDIFWKPQEAVQGDVGSFMIKLVEGLQGQTWSSDWVEELRKADQQKEQTYRDKALLPVPQHLNPVRLLQQVEETLPDNALLVVDGGDFVATAAYLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCQPEAEVWCLFGDGAFGYSLIEFDTFVRHKVPVIALVGNDAGWTQISREQVPRLGSDVACSLAYTDYHKAAMGLGAQGLILSRDNEDQVVKVLRDGQKLCQEGHAVVVNILIGRTDFRDGSISV" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/68532", "id": "68532", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A1L0T0/", "id": "A1L0T0", "database": "OMA" } ], "organism": "Rattus norvegicus", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q8BU33-1", "protein_name": "Acetolactate synthase-like protein; 2.2.1.-; IlvB-like protein.", "sequence": { "length": 632, "sequence": "METSAAAASAGGFFPSFLLLAFGTLVAAVLGVAHRLGLFYQLMHKVDKTSIRHGGESVAAVLRAHGVRFVFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAVARLTGTVGVAAVTAGPGLTNTVTAVKNAQVAQSPVLLLGGAASTLLQKRGALQAIDQMSLFRPLCKFCASVRRVRDIVPTLRTAIAAAQSGTPGPVFVELPLDVLYPYFMVEKEMIPTKLPNSLMGRVVVWYLQNCLANLFVGAWEPRPEGPLPLDIPQASPQQVQRCVEILSRAKRPLLVLGSQALLPPTPANKLRAAVETLGVPCFLGGMSRGLLGRNHPLHIRQNRSAALKKADVVVLAGAVCDFRLSYGRVLNRKSSIIIVNRNRDDLLLNSDIFWKPQEAVQGDVGSFMIKLVEGLQGQMWSSDWAEELRKADQQKEQTYRDKALMPVLQHLNPVWVLQQVEETLPDNALLVVDGGDFVATAAYLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCQPEAEVWCLFGDGAFGYSLIEFDTFVRHKVPVIALVGNDAGWTQISREQVPRLGSDVACSLAYTDYHKAAMGLGAQGLILSRDNKDQVVKVLREGQQLCQDGHAVVVNILIGRTDFRDGSISV" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/68532", "id": "68532", "database": "MGI" } ], "organism": "Mus musculus", "tax_id": 10090 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_006835.2", "ac": "NP_006835.2", "name": "acetolactate synthase-like protein; acetolactate synthase homolog; ilvB-like protein; ilvB (bacterial acetolactate synthase)-like; 2-hydroxyacyl-CoA lyase 1 like.", "summary": "The protein encoded by this gene shares similarity with several thiamine pyrophosphate-binding proteins identified in bacteria, yeast, and plants. The highest degree of similarity is found with bacterial acetolactate synthases (AHAS), which are enzymes that catalyze the first step in branched-chain amino acid biosynthesis. [provided by RefSeq, Jul 2008]." }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L0T0", "id": "A1L0T0", "database": "UniProtKB" } ], "name": "magnesium ion binding", "id": "GO:0000287" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L0T0", "id": "A1L0T0", "database": "UniProtKB" } ], "name": "transferase activity", "id": "GO:0016740" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030976", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L0T0", "id": "A1L0T0", "database": "UniProtKB" } ], "name": "thiamine pyrophosphate binding", "id": "GO:0030976" } ], "total": 3, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L0T0", "id": "A1L0T0", "database": "UniProtKB" } ], "name": "membrane", "id": "GO:0016020" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L0T0", "id": "A1L0T0", "database": "UniProtKB" } ], "name": "integral component of membrane", "id": "GO:0016021" } ], "total": 2, "name": "Cellular Component" } ] }, "site_annotation": [ { "end_pos": 338, "annotation": "n_glycosylation_sequon", "start_pos": 336 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_006835.2", "id": "NP_006835.2", "database": "RefSeq" }, { "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6041", "id": "6041", "database": "HGNC" }, { "url": "https://pharos.nih.gov/targets/A1L0T0", "id": "A1L0T0", "database": "PHAROS" }, { "url": "https://www.nextprot.org/entry/NX_A1L0T0", "id": "NX_A1L0T0", "database": "neXtProt" }, { "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=ILVBL", "id": "ILVBL", "database": "GeneCards" }, { "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:10994", "id": "hsa:10994", "database": "KEGG Pathway" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000105135", "id": "ENSG00000105135", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/LAFTDYH/", "id": "LAFTDYH", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000399", "id": "IPR000399", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR011766", "id": "IPR011766", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR012000", "id": "IPR012000", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR012001", "id": "IPR012001", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR029035", "id": "IPR029035", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR029061", "id": "IPR029061", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00205", "id": "PF00205", 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"database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001987", "uberon": "0001987", "name": "Placenta" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000105135", "id": "ENSG00000105135", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000955", "uberon": "0000955", "name": "Brain" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000105135", "id": "ENSG00000105135", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001160", "uberon": "0001160", "name": "Fundus of stomach" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000105135", "id": "ENSG00000105135", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001150", "uberon": "0001150", "name": "Body of pancreas" }, "present": "yes", "evidence": [ { "url": 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