{
    "uniprot_canonical_ac": "A1EC97-1", 
    "sequence": {
        "header": "tr|A1EC97-1|A1EC97_RAT Isoform 1 of Dual-specificity phosphatase 14  OS=Rattus norvegicus OX=10116 GN=Dusp14 PE=2 SV=1 CANONICAL=A1EC97-1", 
        "length": 198, 
        "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI"
    }, 
    "uniprot_id": "A1EC97_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "dual specificity protein phosphatase 14", 
                "dual specificity phosphatase 14-like 2"
            ], 
            "uniprotkb": [
                "Dual-specificity phosphatase 14", 
                "Dual specificity phosphate 14", 
                "RCG34597, isoform CRA_a"
            ]
        }, 
        "gene": {
            "refseq": [
                "Dusp14", 
                "Dusp14l2"
            ], 
            "uniprotkb": [
                "Dusp14", 
                "Dusp14l1", 
                "rCG_34597", 
                "Dusp14l2"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1EC97", 
                    "id": "A1EC97", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Dual-specificity phosphatase 14; Dual specificity phosphate 14; RCG34597, isoform CRA_a."
    }, 
    "publication": [
        {
            "title": "The Kruppel-Like Factor Gene Target Dusp14 Regulates Axon Growth and Regeneration.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/29860460", 
            "journal": "Investigative ophthalmology & visual science", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073362.1", 
                    "id": "NP_001073362.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Galvao J, Iwao K, Apara A, Wang Y, Ashouri M, Shah TN, Blackmore M, Kunzevitzky NJ, Moore DL, Goldberg JL", 
            "date": "2018", 
            "pmid": "29860460"
        }, 
        {
            "title": "Fine-mapping and comprehensive transcript analysis reveals nonsynonymous variants within a novel 1.17 Mb blood pressure QTL region on rat chromosome 10.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/17218081", 
            "journal": "Genomics", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073362.1", 
                    "id": "NP_001073362.1", 
                    "database": "RefSeq"
                }, 
                {
                    "url": "https://www.uniprot.org/uniprot/A1EC97/publications", 
                    "id": "A1EC97", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Saad Y, Garrett MR, Manickavasagam E, Yerga-Woolwine S, Farms P, Radecki T, Joe B", 
            "date": "2007", 
            "pmid": "17218081"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A1EC97#A1EC97-1", 
            "isoform_ac": "A1EC97-1", 
            "locus": {
                "end_pos": 71364277, 
                "start_pos": 71364870, 
                "chromosome": "10", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000077025", 
                        "id": "ENSRNOT00000077025", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068350", 
                        "id": "ENSRNOP00000068350", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A1EC97-1|A1EC97_RAT Isoform 1 of Dual-specificity phosphatase 14  OS=Rattus norvegicus OX=10116 GN=Dusp14 PE=2 SV=1 CANONICAL=A1EC97-1", 
                "length": 198, 
                "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:360580", 
            "resource": "KEGG Pathway", 
            "id": "rno:360580", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073362.1", 
            "annotation": "These results link intrinsic and extrinsic regulators of axon growth and suggest modulation of the KLF9-Dusp14 pathway as a potential approach to improve regeneration in the adult CNS after injury.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073362.1", 
                    "id": "NP_001073362.1", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9JLY7-1", 
            "protein_name": "Dual specificity protein phosphatase 14; 3.1.3.48; 3.1.3.16; Mitogen-activated protein kinase phosphatase 6; MAP kinase phosphatase 6; MKP-6.", 
            "sequence": {
                "length": 198, 
                "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNWHLLQARGITCVINATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/5100", 
                    "id": "5100", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "O95147-1", 
            "protein_name": "Dual specificity protein phosphatase 14; 3.1.3.48; 3.1.3.16; MKP-1-like protein tyrosine phosphatase; MKP-L; Mitogen-activated protein kinase phosphatase 6; MAP kinase phosphatase 6; MKP-6.", 
            "sequence": {
                "length": 198, 
                "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLMPYWGI"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/5100", 
                    "id": "5100", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "M0R3K8-1", 
            "protein_name": "Dual-specificity phosphatase 14-like 1.", 
            "sequence": {
                "length": 198, 
                "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLVRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/5100", 
                    "id": "5100", 
                    "database": "MGI"
                }
            ], 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073362.1", 
        "ac": "NP_001073362.1", 
        "name": "dual specificity protein phosphatase 14; dual specificity phosphatase 14-like 2.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017017", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1EC97", 
                                "id": "A1EC97", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "MAP kinase tyrosine/serine/threonine phosphatase activity", 
                        "id": "GO:0017017"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1EC97", 
                                "id": "A1EC97", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "protein tyrosine phosphatase activity", 
                        "id": "GO:0004725"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 60, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 58
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073362.1", 
            "id": "NP_001073362.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:360580", 
            "id": "rno:360580", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000030091", 
            "id": "ENSRNOG00000030091", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/YLMKFHS/", 
            "id": "YLMKFHS", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020420", 
            "id": "IPR020420", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", 
            "id": "IPR000340", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", 
            "id": "IPR000387", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", 
            "id": "IPR016130", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", 
            "id": "IPR020422", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020417", 
            "id": "IPR020417", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", 
            "id": "IPR029021", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00782", 
            "id": "PF00782", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/360580", 
            "id": "360580", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1307415", 
            "id": "1307415", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A1EC97", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 22267.0, 
        "chemical_mass": 22267.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A1EC97", 
            "name": "Dusp14; Dusp14l1; rCG_34597; Dusp14l2.", 
            "locus": {
                "end_pos": 71363688, 
                "start_pos": 71383602, 
                "chromosome": "10", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000030091", 
                        "id": "ENSRNOG00000030091", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}