{ "uniprot_canonical_ac": "A1A5Q1-1", "sequence": { "header": "tr|A1A5Q1-1|A1A5Q1_RAT Isoform 1 of Poly [ADP-ribose] polymerase OS=Rattus norvegicus OX=10116 GN=Parp9 PE=1 SV=1 CANONICAL=A1A5Q1-1", "length": 830, "sequence": "MAYYTGTGAAAPTERPADDSLEHYHRWQIPIKHNIFEILKSNESQLYEVLQKKFGCICTLRYPTPAGSSSPAQKVFRRMLTPGIELSVWKDDLTRHVVDAVVNAANEDLLHGGGLAGSLVKIGGSEIQEESKKWIATHGKIPVGGFAVTRAGKLPCYLIIHAVGPRWTVMDSQTAIGLLSVAITNILDYVTKWNTCIKTVAIPALSSGIFQFPLHLCTRIIVETICLYFQDKQTVSNLREIHLVSNEGPTVESFKSSSENIFGKEPSSWESLETNPSSNVTLHIGQGLTLQIVQGCIELQTTDVIVNSGHLQDFKSGQVAQSILKRAGFEMEMELDKIKLSSDYQVVQVTKGFKLSCQYVFHVSWHYSISKDQILKNAMKSCLERCLKRDINSISFPALGTGAINLEKSIAAKIMFEEIVAFAKEHKEKTLTVKIVIFPVDVETYKVFCAEMTKRSSELNLNSDGGLLSLPWTRGEQRSSSLEDGSPAIDLMGVEVGEMCEAKEWIERLLTSKDHHIVENNHILYLGIKEHGMLSQLQTSSNVSISATVSPRTATLEVKGSQADLIEAVMKIECMLCGVQEEVAGKKERSLRSLSGWGTDQQGKLKEMEESCTFQRYPVSLTQEFLDQKKHFDKCGLCVVKVEEVDNEVLLAAFQEKKKMMEEKMPKGSGSQRLFQQVPHQFCNAVCRVGFHRLYSTHNDPVYGAGIYFTKSLKKLADKARKTSSTDRLIYVFEAEVLTGSFCQGNFSNIIPPPLSPGALDVHDSVVDSVSNPETFVIFSGVQAMPRYLWTCTQDRTFSQHPMWSQGYSSEPGMASSLQSWGRVSNGSPV" }, "uniprot_id": "A1A5Q1_RAT", "enzyme_annotation": [ { "ec": "2.4.2.-", "activity": "" } ], "synonyms": { "protein": { "refseq": [ "poly [ADP-ribose] polymerase 9" ], "uniprotkb": [ "Poly [ADP-ribose] polymerase", "PARP", "2.4.2.-" ] }, "gene": { "refseq": [ "Parp9", "RGD1307534" ], "uniprotkb": [ "Parp9", "RGD1307534" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Poly [ADP-ribose] polymerase; PARP; 2.4.2.-.", "short": "PARP" }, "publication": [ { "title": "Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/28525742", "journal": "Molecular cell", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096821.1", "id": "NP_001096821.1", "database": "RefSeq" } ], "authors": "Yang CS, Jividen K, Spencer A, Dworak N, Ni L, Oostdyk LT, Chatterjee M, Kusmider B, Reon B, Parlak M, Gorbunova V, Abbas T, Jeffery E, Sherman NE, Paschal BM", "date": "2017", "pmid": "28525742" }, { "title": "PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/27796300", "journal": "Nature communications", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096821.1", "id": "NP_001096821.1", "database": "RefSeq" } ], "authors": "Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh WW, Halu A, Yamada I, Yoshida H, Hara T, Wei M, Inoue N, Fukuda D, Mojcher A, Mattson PC, Barabasi AL, Boothby M, Aikawa E, Singh SA, Aikawa M", "date": "2016", "pmid": "27796300" }, { "title": "Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/26091342", "journal": "Molecular cell", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096821.1", "id": "NP_001096821.1", "database": "RefSeq" } ], "authors": "Barkauskaite E, Jankevicius G, Ahel I", "date": "2015", "pmid": "26091342" }, { "title": "PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/26479788", "journal": "Nature immunology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096821.1", "id": "NP_001096821.1", "database": "RefSeq" } ], "authors": "Zhang Y, Mao D, Roswit WT, Jin X, Patel AC, Patel DA, Agapov E, Wang Z, Tidwell RM, Atkinson JJ, Huang G, McCarthy R, Yu J, Yun NE, Paessler S, Lawson TG, Omattage NS, Brett TJ, Holtzman MJ", "date": "2015", "pmid": "26479788" }, { "title": "BAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/23230272", "journal": "Molecular and cellular biology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096821.1", "id": "NP_001096821.1", "database": "RefSeq" } ], "authors": "Yan Q, Xu R, Zhu L, Cheng X, Wang Z, Manis J, Shipp MA", "date": "2013", "pmid": "23230272" }, { "title": "BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/16809771", "journal": "Molecular and cellular biology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096821.1", "id": "NP_001096821.1", "database": "RefSeq" } ], "authors": "Juszczynski P, Kutok JL, Li C, Mitra J, Aguiar RC, Shipp MA", "date": "2006", "pmid": "16809771" }, { "title": "B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/16061477", "journal": "The Journal of biological chemistry", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096821.1", "id": "NP_001096821.1", "database": "RefSeq" } ], "authors": "Aguiar RC, Takeyama K, He C, Kreinbrink K, Shipp MA", "date": "2005", "pmid": "16061477" } ], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1#A1A5Q1-1", "isoform_ac": "A1A5Q1-1", "locus": { "end_pos": 67724453, "start_pos": 67755761, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000030975", "id": "ENSRNOT00000030975", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000033812", "id": "ENSRNOP00000033812", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A1A5Q1-1|A1A5Q1_RAT Isoform 1 of Poly [ADP-ribose] polymerase OS=Rattus norvegicus OX=10116 GN=Parp9 PE=1 SV=1 CANONICAL=A1A5Q1-1", "length": 830, "sequence": "MAYYTGTGAAAPTERPADDSLEHYHRWQIPIKHNIFEILKSNESQLYEVLQKKFGCICTLRYPTPAGSSSPAQKVFRRMLTPGIELSVWKDDLTRHVVDAVVNAANEDLLHGGGLAGSLVKIGGSEIQEESKKWIATHGKIPVGGFAVTRAGKLPCYLIIHAVGPRWTVMDSQTAIGLLSVAITNILDYVTKWNTCIKTVAIPALSSGIFQFPLHLCTRIIVETICLYFQDKQTVSNLREIHLVSNEGPTVESFKSSSENIFGKEPSSWESLETNPSSNVTLHIGQGLTLQIVQGCIELQTTDVIVNSGHLQDFKSGQVAQSILKRAGFEMEMELDKIKLSSDYQVVQVTKGFKLSCQYVFHVSWHYSISKDQILKNAMKSCLERCLKRDINSISFPALGTGAINLEKSIAAKIMFEEIVAFAKEHKEKTLTVKIVIFPVDVETYKVFCAEMTKRSSELNLNSDGGLLSLPWTRGEQRSSSLEDGSPAIDLMGVEVGEMCEAKEWIERLLTSKDHHIVENNHILYLGIKEHGMLSQLQTSSNVSISATVSPRTATLEVKGSQADLIEAVMKIECMLCGVQEEVAGKKERSLRSLSGWGTDQQGKLKEMEESCTFQRYPVSLTQEFLDQKKHFDKCGLCVVKVEEVDNEVLLAAFQEKKKMMEEKMPKGSGSQRLFQQVPHQFCNAVCRVGFHRLYSTHNDPVYGAGIYFTKSLKKLADKARKTSSTDRLIYVFEAEVLTGSFCQGNFSNIIPPPLSPGALDVHDSVVDSVSNPETFVIFSGVQAMPRYLWTCTQDRTFSQHPMWSQGYSSEPGMASSLQSWGRVSNGSPV" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/www_bget?rno:303905", "resource": "KEGG Pathway", "id": "rno:303905", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-197264", "resource": "Reactome", "id": "R-RNO-197264", "name": "Nicotinamide salvaging" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q8CAS9-1", "protein_name": "Protein mono-ADP-ribosyltransferase PARP9; 2.4.2.-; ADP-ribosyltransferase diphtheria toxin-like 9; ARTD9; B aggressive lymphoma protein homolog; Poly [ADP-ribose] polymerase 9; PARP-9.", "sequence": { "length": 866, "sequence": "MAYYMDTWAAAPAERPGMIASLSLSFKKAFAELFPQRRRGHSEGDYPPLRGSANNSLEEHYRWQIPIKHNVFEILKSNESQLCEVLQNKFGCISTLSCPTLAGSSSPAQRVFRRTLIPGIELSVWKDDLTRHVVDAVVNAANENLLHGSGLAGSLVKTGGFEIQEESKRIIANVGKISVGGIAITGAGRLPCHLIIHAVGPRWTVTNSQTAIELLKFAIRNILDYVTKYDLRIKTVAIPALSSGIFQFPLDLCTSIILETIRLYFQDKQMFGNLREIHLVSNEDPTVASFKSASESILGRDLSSWGGPETDPASTMTLRIGRGLTLQIVQGCIEMQTTDVIVNSGYMQDFKSGRVAQSILRQAGVEMEKELDKVNLSTDYQEVWVTKGFKLSCQYVFHVAWHSQINKYQILKDAMKSCLEKCLKPDINSISFPALGTGLMDLKKSTAAQIMFEEVFAFAKEHKEKTLTVKIVIFPVDVETYKIFYAEMTKRSNELNLSGNSGALALQWSSGEQRRGGLEAGSPAINLMGVKVGEMCEAQEWIERLLVSLDHHIIENNHILYLGKKEHDVLSELQTSTRVSISETVSPRTATLEIKGPQADLIDAVMRIECMLCDVQEEVAGKREKNLWSLSGQGTNQQEKLDKMEESYTFQRYPASLTQELQDRKKQFEKCGLWVVQVEQIDNKVLLAAFQEKKKMMEERTPKGSGSQRLFQQVPHQFCNTVCRVGFHRMYSTSYNPVYGAGIYFTKSLKNLADKVKKTSSTDKLIYVFEAEVLTGSFCQGNSSNIIPPPLSPGALDVNDSVVDNVSSPETIVVFNGMQAMPLYLWTCTQDRTFSQHPMWSQGYSSGPGMVSSLQSWEWVLNGSSV" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/12720", "id": "12720", "database": "MGI" } ], "organism": "Mus musculus", "tax_id": 10090 }, { "uniprot_canonical_ac": "Q8IXQ6-1", "protein_name": "Protein mono-ADP-ribosyltransferase PARP9; 2.4.2.-; ADP-ribosyltransferase diphtheria toxin-like 9; ARTD9; B aggressive lymphoma protein; Poly [ADP-ribose] polymerase 9; PARP-9.", "sequence": { "length": 854, "sequence": "MDFSMVAGAAAYNEKSGRITSLSLLFQKVFAQIFPQWRKGNTEECLPYKCSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQEYVQSQDYSSGPMRPFAQHPWRGFASGSPVD" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/12720", "id": "12720", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A1A5Q1/", "id": "A1A5Q1", "database": "OMA" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096821.1", "ac": "NP_001096821.1", "name": "poly [ADP-ribose] polymerase 9.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097677", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "STAT family protein binding", "id": "GO:0097677" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "enzyme inhibitor activity", "id": "GO:0004857" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "transcription corepressor activity", "id": "GO:0003714" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "histone binding", "id": "GO:0042393" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "NAD+ ADP-ribosyltransferase activity", "id": "GO:0003950" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072570", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "ADP-D-ribose binding", "id": "GO:0072570" } ], "total": 7, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "nucleoplasm", "id": "GO:0005654" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "mitochondrion", "id": "GO:0005739" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "cytosol", "id": "GO:0005829" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "protein-containing complex", "id": "GO:0032991" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "site of DNA damage", "id": "GO:0090734" } ], "total": 5, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035563", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "positive regulation of chromatin binding", "id": "GO:0035563" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001034", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "positive regulation of double-strand break repair via nonhomologous end joining", "id": "GO:2001034" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "posttranscriptional regulation of gene expression", "id": "GO:0010608" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "positive regulation of transcription, DNA-templated", "id": "GO:0045893" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "double-strand break repair", "id": "GO:0006302" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "positive regulation of defense response to virus by host", "id": "GO:0002230" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006471", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "protein ADP-ribosylation", "id": "GO:0006471" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900182", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "positive regulation of protein localization to nucleus", "id": "GO:1900182" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042531", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "positive regulation of tyrosine phosphorylation of STAT protein", "id": "GO:0042531" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060335", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "id": "A1A5Q1", "database": "UniProtKB" } ], "name": "positive regulation of interferon-gamma-mediated signaling pathway", "id": "GO:0060335" } ], "total": 11, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 44, "annotation": "n_glycosylation_sequon", "start_pos": 42 }, { "end_pos": 281, "annotation": "n_glycosylation_sequon", "start_pos": 279 }, { "end_pos": 544, "annotation": "n_glycosylation_sequon", "start_pos": 542 }, { "end_pos": 748, "annotation": "n_glycosylation_sequon", "start_pos": 746 }, { "end_pos": 828, "annotation": "n_glycosylation_sequon", "start_pos": 826 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096821.1", "id": "NP_001096821.1", "database": "RefSeq" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-197264", "id": "R-RNO-197264", "database": "Reactome" }, { "url": "https://www.genome.jp/dbget-bin/www_bget?rno:303905", "id": "rno:303905", "database": "KEGG Pathway" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000023463", "id": "ENSRNOG00000023463", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/YNEKSGR/", "id": "YNEKSGR", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR002589", "id": "IPR002589", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR012317", "id": "IPR012317", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00644", "id": "PF00644", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF01661", "id": "PF01661", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/303905", "id": "303905", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1307534", "id": "1307534", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A1A5Q1", "disease": [], "mass": { "monoisotopic_mass": 92215.0, "chemical_mass": 92215.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q1", "name": "Parp9; RGD1307534.", "locus": { "end_pos": 67724076, "start_pos": 67756799, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000023463", "id": "ENSRNOG00000023463", "database": "Ensembl Gene" } ] } } ] }