{
    "uniprot_canonical_ac": "A1A5P3-1", 
    "sequence": {
        "header": "tr|A1A5P3-1|A1A5P3_RAT Isoform 1 of RAD51-associated protein 1  OS=Rattus norvegicus OX=10116 GN=Rad51ap1 PE=1 SV=1 CANONICAL=A1A5P3-1", 
        "length": 337, 
        "sequence": "MVRPTRNKKPVNYSQFEDSGNDSDDDFISASIPVNKSKTVPKVLKQDKPKPNLKNLQKEEVLPTEPPKKRMALDDKVFQRGLEVALALSVKELPTLTNQVKKPEERSTDTTGKRKTEKTDKPPRVSNCSVASDDVDLNKITEEGDVRDVEGERRTTSKARAQQRRKLSEGSSGSSADGTEPDSATGEDSESDPDFDESEESDEDFGVRRGKETKKKPVQKKPKAEKKERKSKPKREEASVTSADPAPAAIKSGSPALPQPVGLPSEATRKPAKICSPSAESKRPKWVPPAASGSRNSSSSSWAGTPARSPSQSLRLGLSRLAPVKSLHPSTTSSQVR"
    }, 
    "uniprot_id": "A1A5P3_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "RAD51-associated protein 1"
            ], 
            "uniprotkb": [
                "RAD51-associated protein 1"
            ]
        }, 
        "gene": {
            "refseq": [
                "Rad51ap1"
            ], 
            "uniprotkb": [
                "Rad51ap1"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1A5P3", 
                    "id": "A1A5P3", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "RAD51-associated protein 1."
    }, 
    "publication": [
        {
            "title": "NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/26323318", 
            "journal": "Nucleic acids research", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073179.1", 
                    "id": "NP_001073179.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Parplys AC, Zhao W, Sharma N, Groesser T, Liang F, Maranon DG, Leung SG, Grundt K, Dray E, Idate R, Ostvold AC, Schild D, Sung P, Wiese C", 
            "date": "2015", 
            "pmid": "26323318"
        }, 
        {
            "title": "FIGNL1-containing protein complex is required for efficient homologous recombination repair.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/23754376", 
            "journal": "Proceedings of the National Academy of Sciences of the United States of America", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073179.1", 
                    "id": "NP_001073179.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Yuan J, Chen J", 
            "date": "2013", 
            "pmid": "23754376"
        }, 
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", 
            "journal": "Nat. Commun.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1A5P3/publications", 
                    "id": "A1A5P3", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", 
            "date": "2012", 
            "pmid": "22673903"
        }, 
        {
            "title": "RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/16990250", 
            "journal": "Nucleic acids research", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073179.1", 
                    "id": "NP_001073179.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Kovalenko OV, Wiese C, Schild D", 
            "date": "2006", 
            "pmid": "16990250"
        }, 
        {
            "title": "A novel nucleic acid-binding protein that interacts with human rad51 recombinase.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/9396801", 
            "journal": "Nucleic acids research", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073179.1", 
                    "id": "NP_001073179.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Kovalenko OV, Golub EI, Bray-Ward P, Ward DC, Radding CM", 
            "date": "1997", 
            "pmid": "9396801"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A1A5P3#A1A5P3-1", 
            "isoform_ac": "A1A5P3-1", 
            "locus": {
                "end_pos": 159470584, 
                "start_pos": 159482681, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000088333", 
                        "id": "ENSRNOT00000088333", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073657", 
                        "id": "ENSRNOP00000073657", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A1A5P3-1|A1A5P3_RAT Isoform 1 of RAD51-associated protein 1  OS=Rattus norvegicus OX=10116 GN=Rad51ap1 PE=1 SV=1 CANONICAL=A1A5P3-1", 
                "length": 337, 
                "sequence": "MVRPTRNKKPVNYSQFEDSGNDSDDDFISASIPVNKSKTVPKVLKQDKPKPNLKNLQKEEVLPTEPPKKRMALDDKVFQRGLEVALALSVKELPTLTNQVKKPEERSTDTTGKRKTEKTDKPPRVSNCSVASDDVDLNKITEEGDVRDVEGERRTTSKARAQQRRKLSEGSSGSSADGTEPDSATGEDSESDPDFDESEESDEDFGVRRGKETKKKPVQKKPKAEKKERKSKPKREEASVTSADPAPAAIKSGSPALPQPVGLPSEATRKPAKICSPSAESKRPKWVPPAASGSRNSSSSSWAGTPARSPSQSLRLGLSRLAPVKSLHPSTTSSQVR"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:689055", 
            "resource": "KEGG Pathway", 
            "id": "rno:689055", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5693568", 
            "resource": "Reactome", 
            "id": "R-RNO-5693568", 
            "name": "Resolution of D-loop Structures through Holliday Junction Intermediates"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5693579", 
            "resource": "Reactome", 
            "id": "R-RNO-5693579", 
            "name": "Homologous DNA Pairing and Strand Exchange"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5685942", 
            "resource": "Reactome", 
            "id": "R-RNO-5685942", 
            "name": "HDR through Homologous Recombination (HRR)"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5693537", 
            "resource": "Reactome", 
            "id": "R-RNO-5693537", 
            "name": "Resolution of D-Loop Structures"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5693554", 
            "resource": "Reactome", 
            "id": "R-RNO-5693554", 
            "name": "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q96B01-1", 
            "protein_name": "RAD51-associated protein 1; RAD51-interacting protein.", 
            "sequence": {
                "length": 352, 
                "sequence": "MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRLPEGTFSIPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/48436", 
                    "id": "48436", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A1A5P3/", 
                    "id": "A1A5P3", 
                    "database": "OMA"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "Q8C551-1", 
            "protein_name": "RAD51-associated protein 1; RAD51-interacting protein; RAB22.", 
            "sequence": {
                "length": 337, 
                "sequence": "MVRPTRNRKPINYSQFEDSGNDSDDDFISSSTPVNKSKTVPKVLKQDKPKPNLKNLQKEEVLPTEPPKKRVALDDKVFQRGLEVALALSVKELPTLTNQVKKSKEKSTDKQGKEKTENTGKPPRVSNCSVASDDVEDLDKITEEGDASSVEGERKSPSQAKAPRRRAPSEGSDGSSANDTESESATGEGSESDPDFDESKESDEDFGVRRSKESKKKTVQKKPAGEKKERKSKPKCEASVTSVDPAPAAIKSGSPSLPQAVGLPSEATRKPAIMCSPSAESKRPKWVPPAASGSRNSSSNALAGTPAKSPSQSLRLGLSRLAPVKRLHPSATSSQVR"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/48436", 
                    "id": "48436", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073179.1", 
        "ac": "NP_001073179.1", 
        "name": "RAD51-associated protein 1.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5P3", 
                                "id": "A1A5P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "RNA binding", 
                        "id": "GO:0003723"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5P3", 
                                "id": "A1A5P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "double-stranded DNA binding", 
                        "id": "GO:0003690"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5P3", 
                                "id": "A1A5P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "single-stranded DNA binding", 
                        "id": "GO:0003697"
                    }
                ], 
                "total": 3, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000790", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5P3", 
                                "id": "A1A5P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nuclear chromatin", 
                        "id": "GO:0000790"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5P3", 
                                "id": "A1A5P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "protein-containing complex", 
                        "id": "GO:0032991"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5P3", 
                                "id": "A1A5P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "double-strand break repair via homologous recombination", 
                        "id": "GO:0000724"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071479", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5P3", 
                                "id": "A1A5P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cellular response to ionizing radiation", 
                        "id": "GO:0071479"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5P3", 
                                "id": "A1A5P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "interstrand cross-link repair", 
                        "id": "GO:0036297"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010569", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5P3", 
                                "id": "A1A5P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "regulation of double-strand break repair via homologous recombination", 
                        "id": "GO:0010569"
                    }
                ], 
                "total": 4, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 14, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 12
        }, 
        {
            "end_pos": 23, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 21
        }, 
        {
            "end_pos": 37, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 35
        }, 
        {
            "end_pos": 129, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 127
        }, 
        {
            "end_pos": 298, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 296
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073179.1", 
            "id": "NP_001073179.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5693568", 
            "id": "R-RNO-5693568", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5693579", 
            "id": "R-RNO-5693579", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5685942", 
            "id": "R-RNO-5685942", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5693537", 
            "id": "R-RNO-5693537", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5693554", 
            "id": "R-RNO-5693554", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:689055", 
            "id": "rno:689055", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000059878", 
            "id": "ENSRNOG00000059878", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/GRIPKWN/", 
            "id": "GRIPKWN", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR031419", 
            "id": "IPR031419", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR026632", 
            "id": "IPR026632", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF15696", 
            "id": "PF15696", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15361:SF4", 
            "id": "PTHR15361:SF4", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/689055", 
            "id": "689055", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1597431", 
            "id": "1597431", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A1A5P3", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 36676.0, 
        "chemical_mass": 36676.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A1A5P3", 
            "name": "Rad51ap1.", 
            "locus": {
                "end_pos": 159469804, 
                "start_pos": 159482869, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000059878", 
                        "id": "ENSRNOG00000059878", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}