{ "uniprot_canonical_ac": "A1A5P1-1", "sequence": { "header": "tr|A1A5P1-1|A1A5P1_RAT Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Rattus norvegicus OX=10116 GN=Galnt18 PE=2 SV=1 CANONICAL=A1A5P1-1", "length": 607, "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFEEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCFDQGPDTENVPIVYICHGMTPQNVYYTSSQQIHVGVLSPTIDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGSIQNRKSKRCLELQENSDMEFGFQLVLQKCSGQHWTITNVLRSLVS" }, "uniprot_id": "A1A5P1_RAT", "enzyme_annotation": [ { "ec": "2.4.1.-", "activity": "" } ], "synonyms": { "protein": { "refseq": [ "polypeptide N-acetylgalactosaminyltransferase 18", "polypeptide N-acetylgalactosaminyltransferase-like 4; putative polypeptide N-acetylgalactosaminyltransferase-like protein 4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4" ], "uniprotkb": [ "Polypeptide N-acetylgalactosaminyltransferase", "2.4.1.-", "Protein-UDP acetylgalactosaminyltransferase" ] }, "gene": { "refseq": [ "Galnt18", "Galntl4", "RGD1309623" ], "uniprotkb": [ "Galnt18", "Galntl4", "rCG_39382", "Galntl4_predicted", "RGD1309623" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5P1", "id": "A1A5P1", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A1A5P1#A1A5P1-1", "isoform_ac": "A1A5P1-1", "locus": { "end_pos": 176296470, "start_pos": 176607056, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000022984", "id": "ENSRNOT00000022984", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000022984", "id": "ENSRNOP00000022984", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A1A5P1-1|A1A5P1_RAT Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Rattus norvegicus OX=10116 GN=Galnt18 PE=2 SV=1 CANONICAL=A1A5P1-1", "length": 607, "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFEEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCFDQGPDTENVPIVYICHGMTPQNVYYTSSQQIHVGVLSPTIDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGSIQNRKSKRCLELQENSDMEFGFQLVLQKCSGQHWTITNVLRSLVS" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/www_bget?rno:293181", "resource": "KEGG Pathway", "id": "rno:293181", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-913709", "resource": "Reactome", "id": "R-RNO-913709", "name": "O-linked glycosylation of mucins" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q8K1B9-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 18; 2.4.1.41; Polypeptide GalNAc transferase-like protein 4; GalNAc-T-like protein 4; pp-GaNTase-like protein 4; Polypeptide GalNAc transferase 18; GalNAc-T18; Polypeptide N-acetylgalactosaminyltransferase-like protein 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 4; Protein-UDP acetylgalactosaminyltransferase-like protein 4.", "sequence": { "length": 622, "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPVPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFEEIGLLDEGMEVYGGENVELGIRVSEISHTGLSSAPMMVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTENVPIVYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGSIQNRKSKRCLELQENSDMEFGFQLVLQKCSGQHWTITNVLRSLVS" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/18347", "id": "18347", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A1A5P1/", "id": "A1A5P1", "database": "OMA" } ], "organism": "Mus musculus", "tax_id": 10090 }, { "uniprot_canonical_ac": "Q6P9A2-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 18; 2.4.1.41; Polypeptide GalNAc transferase-like protein 4; GalNAc-T-like protein 4; pp-GaNTase-like protein 4; Polypeptide GalNAc transferase 18; GalNAc-T18; Polypeptide N-acetylgalactosaminyltransferase-like protein 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 4; Protein-UDP acetylgalactosaminyltransferase-like protein 4.", "sequence": { "length": 607, "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNSQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTENVPIMYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGPIQNRKSKRCLELQENSDLEFGFQLVLQKCSGQHWSITNVLRSLAS" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/18347", "id": "18347", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A1A5P1/", "id": "A1A5P1", "database": "OMA" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073353.1", "ac": "NP_001073353.1", "name": "polypeptide N-acetylgalactosaminyltransferase 18; polypeptide N-acetylgalactosaminyltransferase-like 4; putative polypeptide N-acetylgalactosaminyltransferase-like protein 4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5P1", "id": "A1A5P1", "database": "UniProtKB" } ], "name": "carbohydrate binding", "id": "GO:0030246" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004653", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5P1", "id": "A1A5P1", "database": "UniProtKB" } ], "name": "polypeptide N-acetylgalactosaminyltransferase activity", "id": "GO:0004653" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5P1", "id": "A1A5P1", "database": "UniProtKB" } ], "name": "Golgi apparatus", "id": "GO:0005794" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5P1", "id": "A1A5P1", "database": "UniProtKB" } ], "name": "Golgi membrane", "id": "GO:0000139" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5P1", "id": "A1A5P1", "database": "UniProtKB" } ], "name": "integral component of membrane", "id": "GO:0016021" } ], "total": 3, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5P1", "id": "A1A5P1", "database": "UniProtKB" } ], "name": "protein O-linked glycosylation", "id": "GO:0006493" } ], "total": 1, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 148, "annotation": "n_glycosylation_sequon", "start_pos": 146 }, { "end_pos": 197, "annotation": "n_glycosylation_sequon", "start_pos": 195 }, { "end_pos": 322, "annotation": "n_glycosylation_sequon", "start_pos": 320 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073353.1", "id": "NP_001073353.1", "database": "RefSeq" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-913709", "id": "R-RNO-913709", "database": "Reactome" }, { "url": "https://www.genome.jp/dbget-bin/www_bget?rno:293181", "id": "rno:293181", "database": "KEGG Pathway" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000017021", "id": "ENSRNOG00000017021", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/NNENEFG/", "id": "NNENEFG", "database": "OMA" }, { "url": "http://www.cazy.org/fam/CBM13.html", "id": "CBM13", "database": "CAZy" }, { "url": "http://www.cazy.org/fam/GT27.html", "id": "GT27", "database": "CAZy" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00161", "id": "cd00161", "database": "CDD" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "id": "IPR029044", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001173", "id": "IPR001173", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "id": "IPR000772", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "id": "IPR035992", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00535", "id": "PF00535", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00652", "id": "PF00652", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/293181", "id": "293181", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1309623", "id": "1309623", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A1A5P1", "disease": [], "mass": { "monoisotopic_mass": 69574.0, "chemical_mass": 69574.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A1A5P1", "name": "Galnt18; Galntl4; rCG_39382; Galntl4_predicted; RGD1309623.", "locus": { "end_pos": 176296193, "start_pos": 176607466, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000017021", "id": "ENSRNOG00000017021", "database": "Ensembl Gene" } ] } } ] }