{
    "uniprot_canonical_ac": "A0PK05-1", 
    "sequence": {
        "header": "sp|A0PK05-1|TMM72_HUMAN Isoform 1 of Transmembrane protein 72  OS=Homo sapiens OX=9606 GN=TMEM72 PE=2 SV=1 CANONICAL=A0PK05-1", 
        "length": 275, 
        "sequence": "MQLQVFWTGLEYTCRLLGITTAAVLIGVGTETFLQGQFKSLAFYLLFTGAAVSICEGAYFVAQLLAICFQCQPGSLADRVREKAHWLGCFQKFLAYLLLSVACFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKRKAAPEVLASPEQYTDPSSSAVSTTGSGDTEQTYTFHGALKEGPSSLFIHMKSILKGTKKPSALQPPNTLMELSLEPADSLAKKKQVHFEDNLVRIVPSLAEGLDDGDSEPEETTSDTTPIIPPPQAPLFLSSLTATGLF"
    }, 
    "uniprot_id": "TMM72_HUMAN", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "transmembrane protein 72 isoform 1", 
                "kidney-specific secretory protein of 37 kDa"
            ], 
            "uniprotkb": [
                "Transmembrane protein 72", 
                "Kidney-specific secretory protein of 37 kDa"
            ]
        }, 
        "gene": {
            "refseq": [
                "TMEM72", 
                "C10orf127", 
                "KSP37"
            ], 
            "uniprotkb": [
                "TMEM72", 
                "KSP37", 
                "C10orf127"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0PK05", 
                    "id": "A0PK05", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Transmembrane protein 72; Kidney-specific secretory protein of 37 kDa."
    }, 
    "publication": [
        {
            "title": "Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/26169495", 
            "journal": "BMC cancer", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116848.1", 
                    "id": "NP_001116848.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Wrzesinski T, Szelag M, Cieslikowski WA, Ida A, Giles R, Zodro E, Szumska J, Pozniak J, Kwias Z, Bluyssen HA, Wesoly J", 
            "date": "2015", 
            "pmid": "26169495"
        }, 
        {
            "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/12477932", 
            "journal": "Proceedings of the National Academy of Sciences of the United States of America", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116848.1", 
                    "id": "NP_001116848.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA", 
            "date": "2002", 
            "pmid": "12477932"
        }
    ], 
    "glycosylation": [], 
    "mutation": [
        {
            "start_pos": 40, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.5", 
            "annotation": "Filters passed (1/5): patient freq. (1.5%).", 
            "sequence_org": "S", 
            "disease": {
                "doid": "1324", 
                "url": "http://disease-ontology.org/term/DOID:1324", 
                "icd10": "", 
                "name": "Lung cancer"
            }, 
            "sequence_mut": "R", 
            "subjects_tested": "66", 
            "end_pos": 40, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 103, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "C", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "R", 
            "subjects_tested": "50", 
            "end_pos": 103, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 89, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "C", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "Y", 
            "subjects_tested": "50", 
            "end_pos": 89, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 35, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "Q", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "*", 
            "subjects_tested": "50", 
            "end_pos": 35, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 41, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.5", 
            "annotation": "Filters passed (1/5): patient freq. (1.5%).", 
            "sequence_org": "L", 
            "disease": {
                "doid": "1324", 
                "url": "http://disease-ontology.org/term/DOID:1324", 
                "icd10": "", 
                "name": "Lung cancer"
            }, 
            "sequence_mut": "M", 
            "subjects_tested": "66", 
            "end_pos": 41, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 62, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.1", 
            "annotation": "Filters passed (1/5): patient freq. (2.1%).", 
            "sequence_org": "A", 
            "disease": {
                "doid": "2531", 
                "url": "http://disease-ontology.org/term/DOID:2531", 
                "icd10": "", 
                "name": "Hematologic cancer"
            }, 
            "sequence_mut": "S", 
            "subjects_tested": "48", 
            "end_pos": 62, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 84, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "A", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "D", 
            "subjects_tested": "50", 
            "end_pos": 84, 
            "type": "Point mutation"
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0PK05#A0PK05-1", 
            "isoform_ac": "A0PK05-1", 
            "locus": {
                "end_pos": 44911513, 
                "start_pos": 44935131, 
                "chromosome": "10", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000389583", 
                        "id": "ENST00000389583", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000374234", 
                        "id": "ENSP00000374234", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A0PK05-1|TMM72_HUMAN Isoform 1 of Transmembrane protein 72  OS=Homo sapiens OX=9606 GN=TMEM72 PE=2 SV=1 CANONICAL=A0PK05-1", 
                "length": 275, 
                "sequence": "MQLQVFWTGLEYTCRLLGITTAAVLIGVGTETFLQGQFKSLAFYLLFTGAAVSICEGAYFVAQLLAICFQCQPGSLADRVREKAHWLGCFQKFLAYLLLSVACFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKRKAAPEVLASPEQYTDPSSSAVSTTGSGDTEQTYTFHGALKEGPSSLFIHMKSILKGTKKPSALQPPNTLMELSLEPADSLAKKKQVHFEDNLVRIVPSLAEGLDDGDSEPEETTSDTTPIIPPPQAPLFLSSLTATGLF"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0PK05#A0PK05-2", 
            "isoform_ac": "A0PK05-2", 
            "locus": {
                "end_pos": 44934661, 
                "start_pos": 44935131, 
                "chromosome": "10", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000544540", 
                        "id": "ENST00000544540", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000439911", 
                        "id": "ENSP00000439911", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A0PK05-2|TMM72_HUMAN Isoform 2 of Transmembrane protein 72  OS=Homo sapiens OX=9606 GN=TMEM72 PE=2 SV=1 CANONICAL=A0PK05-1", 
                "length": 157, 
                "sequence": "MLIITGLAYFLLSKRKKRKAAPEVLASPEQYTDPSSSAVSTTGSGDTEQTYTFHGALKEGPSSLFIHMKSILKGTKKPSALQPPNTLMELSLEPADSLAKKKQVHFEDNLVRIVPSLAEGLDDGDSEPEETTSDTTPIIPPPQAPLFLSSLTATGLF"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:643236", 
            "resource": "KEGG Pathway", 
            "id": "hsa:643236", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "D4A2U6-1", 
            "protein_name": "LOC362424 (Predicted); Transmembrane protein 72.", 
            "sequence": {
                "length": 275, 
                "sequence": "MKLQVFWTGLEYTCRLLGITTAAVLIGVGTETFLRGRFKSLAFYLLFTGVTISVCEGTYFVAQLLAICFKCQPGSLAHRAKEKAHWLGCFQKFLAYMLLSVACFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKKKAAPEVMPPTEQYRDPSSSIVSTTGSGDTEQTYTFHEAFKEGPSSFLIHMKSILKGTKKPRVLQAQDTLMELALEPADSLAKKKQVHFEDNVVRIIPSLTEGLGDSDSGPEETSSDTTPIIPPSQTPLFLPSLMATDLF"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/18704", 
                    "id": "18704", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A0PK05/", 
                    "id": "A0PK05", 
                    "database": "OMA"
                }
            ], 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q8C3K5-1", 
            "protein_name": "Transmembrane protein 72.", 
            "sequence": {
                "length": 275, 
                "sequence": "MKLQVFWTGLEYTCRLLGIATAAVLIGVGTETFLRGRFKSLAFYLLFTGVTISVCEGTYFVAQLLAICFKCQPGSLAHRAKERAHWLGCFQKFLAYMLLSVACFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKKKAAPEVAPPTEQYTDPSSSVVSTTGSGDTEQTYTFHEAFKEGPGSFFIHMKSILKGTKKPRVLQTQDTLMELALEPADSLAKKKQVHFEDNVVRIIPSLTEGLGDSDSEPEETSSDTTPIIPPSQTPHFLPSLMATDLF"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/18704", 
                    "id": "18704", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A0PK05/", 
                    "id": "A0PK05", 
                    "database": "OMA"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116848.1", 
        "ac": "NP_001116848.1", 
        "name": "transmembrane protein 72 isoform 1; kidney-specific secretory protein of 37 kDa.", 
        "summary": "This gene encodes a transmembrane protein which may be expressed specifically in the kidney. [provided by RefSeq, Sep 2016]."
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0PK05", 
                                "id": "A0PK05", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116848.1", 
            "id": "NP_001116848.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=31658", 
            "id": "31658", 
            "database": "HGNC"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A0PK05", 
            "id": "A0PK05", 
            "database": "PHAROS"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A0PK05", 
            "id": "NX_A0PK05", 
            "database": "neXtProt"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=TMEM72", 
            "id": "TMEM72", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:643236", 
            "id": "hsa:643236", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
            "id": "ENSG00000187783", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/RWLGCFQ/", 
            "id": "RWLGCFQ", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032055", 
            "id": "IPR032055", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF16054", 
            "id": "PF16054", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28474", 
            "id": "PTHR28474", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A0PK05", 
            "id": "PR_A0PK05", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A0PK05*", 
            "id": "A0PK05", 
            "database": "IntAct"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/643236", 
            "id": "643236", 
            "database": "GeneID"
        }
    ], 
    "expression_disease": [
        {
            "trend": "Up", 
            "disease": {
                "doid": "3571", 
                "url": "http://disease-ontology.org/term/DOID:3571", 
                "icd10": "", 
                "name": "DOID:3571 / Liver cancer [Livca]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "5041", 
                "url": "http://disease-ontology.org/term/DOID:5041", 
                "icd10": "", 
                "name": "DOID:5041 / Esophageal cancer [EC]"
            }, 
            "significant": "Yes", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "3910", 
                "url": "http://disease-ontology.org/term/DOID:3910", 
                "icd10": "", 
                "name": "DOID:3910 / Lung adenocarcinoma"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "DOID:1781 / Thyroid cancer [Thyca]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "11054", 
                "url": "http://disease-ontology.org/term/DOID:11054", 
                "icd10": "", 
                "name": "DOID:11054 / Urinary bladder cancer [UBC]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "3907", 
                "url": "http://disease-ontology.org/term/DOID:3907", 
                "icd10": "", 
                "name": "DOID:3907 / Lung squamous cell carcinoma"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "10283", 
                "url": "http://disease-ontology.org/term/DOID:10283", 
                "icd10": "", 
                "name": "DOID:10283 / Prostate cancer [PCa]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PK05", 
                    "id": "A0PK05", 
                    "database": "BioXpress"
                }
            ]
        }
    ], 
    "uniprot_ac": "A0PK05", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 29891.0, 
        "chemical_mass": 29891.0
    }, 
    "expression_tissue": [
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0009853", 
                "uberon": "0009853", 
                "name": "Body of uterus"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000458", 
                "uberon": "0000458", 
                "name": "Endocervix"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000948", 
                "uberon": "0000948", 
                "name": "Heart"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000473", 
                "uberon": "0000473", 
                "name": "Testis"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002369", 
                "uberon": "0002369", 
                "name": "Adrenal gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000992", 
                "uberon": "0000992", 
                "name": "Ovary"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000996", 
                "uberon": "0000996", 
                "name": "Vagina"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001155", 
                "uberon": "0001155", 
                "name": "Colon"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001987", 
                "uberon": "0001987", 
                "name": "Placenta"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000955", 
                "uberon": "0000955", 
                "name": "Brain"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001160", 
                "uberon": "0001160", 
                "name": "Fundus of stomach"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001150", 
                "uberon": "0001150", 
                "name": "Body of pancreas"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002048", 
                "uberon": "0002048", 
                "name": "Lung"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000007", 
                "uberon": "0000007", 
                "name": "Pituitary gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002107", 
                "uberon": "0002107", 
                "name": "Liver"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002046", 
                "uberon": "0002046", 
                "name": "Thyroid gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000178", 
                "uberon": "0000178", 
                "name": "Blood"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001043", 
                "uberon": "0001043", 
                "name": "Esophagus"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002367", 
                "uberon": "0002367", 
                "name": "Prostate gland"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001161", 
                "uberon": "0001161", 
                "name": "Body of stomach"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001255", 
                "uberon": "0001255", 
                "name": "Urinary bladder"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000187783", 
                    "id": "ENSG00000187783", 
                    "database": "Bgee"
                }
            ]
        }
    ], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0PK05", 
            "name": "TMEM72; KSP37; C10orf127.", 
            "locus": {
                "end_pos": 44937002, 
                "start_pos": 44911200, 
                "chromosome": "10", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000187783", 
                        "id": "ENSG00000187783", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}