{
    "uniprot_canonical_ac": "A0PJE2-1", 
    "sequence": {
        "header": "sp|A0PJE2-1|DHR12_HUMAN Isoform 1 of Dehydrogenase/reductase SDR family member 12  OS=Homo sapiens OX=9606 GN=DHRS12 PE=2 SV=2 CANONICAL=A0PJE2-1", 
        "length": 317, 
        "sequence": "MSLYRSVVWFAKGLREYTKSGYESACKDFVPHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHPGWADTPGVRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQDRKPVSTHLPLATASSSPAEEEKLIEILEQLAQTFK"
    }, 
    "uniprot_id": "DHR12_HUMAN", 
    "enzyme_annotation": [
        {
            "ec": "1.1.-.-", 
            "activity": ""
        }
    ], 
    "synonyms": {
        "protein": {
            "refseq": [
                "dehydrogenase/reductase SDR family member 12 isoform 1", 
                "short-chain dehydrogenase/reductase family 40C member 1; dehydrogenase/reductase (SDR family) member 12"
            ], 
            "uniprotkb": [
                "Dehydrogenase/reductase SDR family member 12", 
                "1.1.-.-", 
                "reductase family 40C member 1"
            ]
        }, 
        "gene": {
            "refseq": [
                "DHRS12", 
                "SDR40C1"
            ], 
            "uniprotkb": [
                "DHRS12", 
                "SDR40C1"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Dehydrogenase/reductase SDR family member 12; 1.1.-.-; reductase family 40C member 1."
    }, 
    "publication": [
        {
            "title": "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/19027726", 
            "journal": "Chemico-biological interactions", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026889.1", 
                    "id": "NP_001026889.1", 
                    "database": "RefSeq"
                }, 
                {
                    "url": "https://www.uniprot.org/uniprot/A0PJE2/publications", 
                    "id": "A0PJE2", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U", 
            "date": "2009", 
            "pmid": "19027726"
        }
    ], 
    "glycosylation": [], 
    "mutation": [
        {
            "start_pos": 3, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "L", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "M", 
            "subjects_tested": "50", 
            "end_pos": 3, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 31, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "P", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "T", 
            "subjects_tested": "50", 
            "end_pos": 31, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 101, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "S", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "T", 
            "subjects_tested": "50", 
            "end_pos": 101, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 155, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.5", 
            "annotation": "Filters passed (1/5): patient freq. (1.5%). In dbSNP: rs765630168.", 
            "sequence_org": "T", 
            "disease": {
                "doid": "1324", 
                "url": "http://disease-ontology.org/term/DOID:1324", 
                "icd10": "", 
                "name": "Lung cancer"
            }, 
            "sequence_mut": "M", 
            "subjects_tested": "66", 
            "end_pos": 155, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 280, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "F", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "S", 
            "subjects_tested": "50", 
            "end_pos": 280, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 83, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "E", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "D", 
            "subjects_tested": "50", 
            "end_pos": 83, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 227, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.1", 
            "annotation": "Filters passed (1/5): patient freq. (2.1%).", 
            "sequence_org": "M", 
            "disease": {
                "doid": "2531", 
                "url": "http://disease-ontology.org/term/DOID:2531", 
                "icd10": "", 
                "name": "Hematologic cancer"
            }, 
            "sequence_mut": "I", 
            "subjects_tested": "48", 
            "end_pos": 227, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 250, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "D", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "Y", 
            "subjects_tested": "50", 
            "end_pos": 250, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 276, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "S", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "G", 
            "subjects_tested": "50", 
            "end_pos": 276, 
            "type": "Point mutation"
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0PJE2#A0PJE2-2", 
            "isoform_ac": "A0PJE2-2", 
            "locus": {
                "end_pos": 51769127, 
                "start_pos": 51799659, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000218981", 
                        "id": "ENST00000218981", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000218981", 
                        "id": "ENSP00000218981", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A0PJE2-2|DHR12_HUMAN Isoform 2 of Dehydrogenase/reductase SDR family member 12  OS=Homo sapiens OX=9606 GN=DHRS12 PE=2 SV=2 CANONICAL=A0PJE2-1", 
                "length": 242, 
                "sequence": "MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHPGWADTPGVRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQGDFLPGCEGS"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0PJE2#A0A087WUE0-1", 
            "isoform_ac": "A0A087WUE0-1", 
            "locus": {
                "end_pos": 51772953, 
                "start_pos": 51790062, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000461948", 
                        "id": "ENST00000461948", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000478573", 
                        "id": "ENSP00000478573", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A087WUE0-1|DHR12_HUMAN Computationally mapped isoform of Dehydrogenase/reductase SDR family member 12  OS=Homo sapiens OX=9606 GN=DHRS12 PE=2 SV=1 CANONICAL=A0PJE2-1", 
                "length": 100, 
                "sequence": "RELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKGAHIVCKAASTLRLPCRCCVPSEGGPV"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0PJE2#A0PJE2-3", 
            "isoform_ac": "A0PJE2-3", 
            "locus": {
                "end_pos": 51771242, 
                "start_pos": 51799659, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000280056", 
                        "id": "ENST00000280056", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000280056", 
                        "id": "ENSP00000280056", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A0PJE2-3|DHR12_HUMAN Isoform 3 of Dehydrogenase/reductase SDR family member 12  OS=Homo sapiens OX=9606 GN=DHRS12 PE=2 SV=2 CANONICAL=A0PJE2-1", 
                "length": 271, 
                "sequence": "MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHPGWADTPDRNEQELRKVVGEAQTASPLPRFLEIMMHEGKCQPQGHSSNDLEACWSSGGGEQNSLPDWPHQLHDLRQLTWALCSSFLLYKQGN"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0PJE2#A0A494C138-1", 
            "isoform_ac": "A0A494C138-1", 
            "locus": {
                "end_pos": 51791165, 
                "start_pos": 51799659, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000650833", 
                        "id": "ENST00000650833", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000498848", 
                        "id": "ENSP00000498848", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A494C138-1|DHR12_HUMAN Computationally mapped isoform of Dehydrogenase/reductase SDR family member 12  OS=Homo sapiens OX=9606 GN=DHRS12 PE=2 SV=1 CANONICAL=A0PJE2-1", 
                "length": 100, 
                "sequence": "MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSEVAQFTWFVEIKPQQKMPGVRSSGRAVTRTFFCTLWTCLIPSKSGNLLKISSRNINSMF"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0PJE2#A0PJE2-1", 
            "isoform_ac": "A0PJE2-1", 
            "locus": {
                "end_pos": 51768190, 
                "start_pos": 51804109, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000444610", 
                        "id": "ENST00000444610", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000411565", 
                        "id": "ENSP00000411565", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A0PJE2-1|DHR12_HUMAN Isoform 1 of Dehydrogenase/reductase SDR family member 12  OS=Homo sapiens OX=9606 GN=DHRS12 PE=2 SV=2 CANONICAL=A0PJE2-1", 
                "length": 317, 
                "sequence": "MSLYRSVVWFAKGLREYTKSGYESACKDFVPHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHPGWADTPGVRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQDRKPVSTHLPLATASSSPAEEEKLIEILEQLAQTFK"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:79758", 
            "resource": "KEGG Pathway", 
            "id": "hsa:79758", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A0PJE2#function", 
            "annotation": "Putative oxidoreductase.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0PJE2#function", 
                    "id": "A0PJE2", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026889.1", 
        "ac": "NP_001026889.1", 
        "name": "dehydrogenase/reductase SDR family member 12 isoform 1; short-chain dehydrogenase/reductase family 40C member 1; dehydrogenase/reductase (SDR family) member 12.", 
        "summary": "This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members in this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]."
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0PJE2", 
                                "id": "A0PJE2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "oxidoreductase activity", 
                        "id": "GO:0016491"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }
        ]
    }, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026889.1", 
            "id": "NP_001026889.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=25832", 
            "id": "25832", 
            "database": "HGNC"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A0PJE2", 
            "id": "A0PJE2", 
            "database": "PHAROS"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A0PJE2", 
            "id": "NX_A0PJE2", 
            "database": "neXtProt"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=DHRS12", 
            "id": "DHRS12", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:79758", 
            "id": "hsa:79758", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000102796", 
            "id": "ENSG00000102796", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/KNENVHV/", 
            "id": "KNENVHV", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", 
            "id": "IPR036291", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", 
            "id": "IPR002347", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00106", 
            "id": "PF00106", 
            "database": "Pfam"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A0PJE2", 
            "id": "PR_A0PJE2", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/79758", 
            "id": "79758", 
            "database": "GeneID"
        }
    ], 
    "expression_disease": [
        {
            "trend": "Down", 
            "disease": {
                "doid": "5041", 
                "url": "http://disease-ontology.org/term/DOID:5041", 
                "icd10": "", 
                "name": "DOID:5041 / Esophageal cancer [EC]"
            }, 
            "significant": "Yes", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "3910", 
                "url": "http://disease-ontology.org/term/DOID:3910", 
                "icd10": "", 
                "name": "DOID:3910 / Lung adenocarcinoma"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "10283", 
                "url": "http://disease-ontology.org/term/DOID:10283", 
                "icd10": "", 
                "name": "DOID:10283 / Prostate cancer [PCa]"
            }, 
            "significant": "Yes", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "11054", 
                "url": "http://disease-ontology.org/term/DOID:11054", 
                "icd10": "", 
                "name": "DOID:11054 / Urinary bladder cancer [UBC]"
            }, 
            "significant": "Yes", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "DOID:1781 / Thyroid cancer [Thyca]"
            }, 
            "significant": "No", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A0PJE2", 
                    "id": "A0PJE2", 
                    "database": "BioXpress"
                }
            ]
        }, 
        {
            "trend": "Down", 
            "disease": {
                "doid": "3907", 
                "url": "http://disease-ontology.org/term/DOID:3907", 
                "icd10": "", 
                "name": "DOID:3907 / Lung squamous cell carcinoma"
            }, 
            "significant": "Yes", 
            "evidence": [
                {
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                }
            ]
        }, 
        {
            "trend": "Down", 
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                "url": "http://disease-ontology.org/term/DOID:3571", 
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            }, 
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            "evidence": [
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                }
            ]
        }
    ], 
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    "disease": [], 
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        "chemical_mass": 35146.0
    }, 
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                "name": "Heart"
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        {
            "tissue": {
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                "name": "Testis"
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            "present": "yes", 
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                "name": "Adrenal gland"
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            "evidence": [
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        {
            "tissue": {
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                "name": "Ovary"
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            "present": "yes", 
            "evidence": [
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            "tissue": {
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            "tissue": {
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                "name": "Body of pancreas"
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            "tissue": {
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        {
            "tissue": {
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        {
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                "name": "Blood"
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        {
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            "evidence": [
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                "name": "Prostate gland"
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            "evidence": [
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                    "id": "ENSG00000102796", 
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            "tissue": {
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                "name": "Body of stomach"
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            "evidence": [
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            ]
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    ], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0PJE2", 
            "name": "DHRS12; SDR40C1.", 
            "locus": {
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                "start_pos": 51804157, 
                "chromosome": "13", 
                "evidence": [
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                        "id": "ENSG00000102796", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}