{
    "uniprot_canonical_ac": "A0JN28-1", 
    "sequence": {
        "header": "tr|A0JN28-1|A0JN28_RAT Isoform 1 of Leucine-rich repeat-containing 52  OS=Rattus norvegicus OX=10116 GN=Lrrc52 PE=2 SV=1 CANONICAL=A0JN28-1", 
        "length": 314, 
        "sequence": "MSLASGPSPKLLLFSLGMGLVSGSKCPNNCLCQDQEVACTDLQLTEYPTDIPLNTRRLYLNNNKITSLPALQLGFLSDLVYLDCQNNRIREVMDYTFIGIFKLLYLDLSSNNLTSISPFSFSILTNLVRLNISNNPHLLYLDKYIFANTTSLRYLDLRNTGMQIIDHTGFHHLVVLQTLYLSGNPWKCNCSFLDFTIHLLVSHMDHPDAQNATCTEPPELKGWPITKVGNPLQYMCITHLDHQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQNALRKSSGDDTEDETGNRITNQMFRSNTHLAPVRRFPELI"
    }, 
    "uniprot_id": "A0JN28_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "leucine-rich repeat-containing protein 52 precursor", 
                "leucine-rich repeat-containing protein 52"
            ], 
            "uniprotkb": [
                "Leucine-rich repeat-containing 52"
            ]
        }, 
        "gene": {
            "refseq": [
                "Lrrc52", 
                "RGD1312014"
            ], 
            "uniprotkb": [
                "Lrrc52", 
                "RGD1312014_predicted", 
                "RGD1312014"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0JN28", 
                    "id": "A0JN28", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Leucine-rich repeat-containing 52."
    }, 
    "publication": [
        {
            "title": "SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertility.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/25675513", 
            "journal": "Proceedings of the National Academy of Sciences of the United States of America", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070902.1", 
                    "id": "NP_001070902.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Zeng XH, Yang C, Xia XM, Liu M, Lingle CJ", 
            "date": "2015", 
            "pmid": "25675513"
        }, 
        {
            "title": "BK potassium channel modulation by leucine-rich repeat-containing proteins.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/22547800", 
            "journal": "Proceedings of the National Academy of Sciences of the United States of America", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070902.1", 
                    "id": "NP_001070902.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Yan J, Aldrich RW", 
            "date": "2012", 
            "pmid": "22547800"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0JN28#A0JN28-1", 
            "isoform_ac": "A0JN28-1", 
            "locus": {
                "end_pos": 85672148, 
                "start_pos": 85695076, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000005768", 
                        "id": "ENSRNOT00000005768", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000005768", 
                        "id": "ENSRNOP00000005768", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0JN28-1|A0JN28_RAT Isoform 1 of Leucine-rich repeat-containing 52  OS=Rattus norvegicus OX=10116 GN=Lrrc52 PE=2 SV=1 CANONICAL=A0JN28-1", 
                "length": 314, 
                "sequence": "MSLASGPSPKLLLFSLGMGLVSGSKCPNNCLCQDQEVACTDLQLTEYPTDIPLNTRRLYLNNNKITSLPALQLGFLSDLVYLDCQNNRIREVMDYTFIGIFKLLYLDLSSNNLTSISPFSFSILTNLVRLNISNNPHLLYLDKYIFANTTSLRYLDLRNTGMQIIDHTGFHHLVVLQTLYLSGNPWKCNCSFLDFTIHLLVSHMDHPDAQNATCTEPPELKGWPITKVGNPLQYMCITHLDHQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQNALRKSSGDDTEDETGNRITNQMFRSNTHLAPVRRFPELI"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:289199", 
            "resource": "KEGG Pathway", 
            "id": "rno:289199", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q5M8M9-1", 
            "protein_name": "Leucine-rich repeat-containing protein 52; BK channel auxiliary gamma subunit LRRC52.", 
            "sequence": {
                "length": 314, 
                "sequence": "MSLASGPSSKLLLFSLGMGLVSGSKCPNKCVCQDQEVACIDLHLTEYPADIPLNTRRLYLNNNKITSLPALQLGFLSDLVYLDCQNNRIREVMDYTFIGIFRLIYLDLSSNNLTSISPFSFSVLTNLVRLNISHNPHLLYLDKYVFANTTSLRYLDLRNTGLHIIDHNGFHHLVVLQTLYLSGNPWICNCSFLDFTIHLLVSHMDHPDAQNATCTEPAELKGWPITKVGNPLQYMCITHLDQQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQNALRTSSGDDTEDETGSRFANQIFRSNTHLGPIRRFPELI"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0JN28/", 
                    "id": "A0JN28", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/35430", 
                    "id": "35430", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q8N7C0-1", 
            "protein_name": "Leucine-rich repeat-containing protein 52; BK channel auxiliary gamma subunit LRRC52.", 
            "sequence": {
                "length": 313, 
                "sequence": "MSLASGPGPGWLLFSFGMGLVSGSKCPNNCLCQAQEVICTGKQLTEYPLDIPLNTRRLFLNENRITSLPAMHLGLLSDLVYLDCQNNRIREVMDYTFIGVFKLIYLDLSSNNLTSISPFTFSVLSNLVQLNIANNPHLLSLHKFTFANTTSLRYLDLRNTGLQTLDSAALYHLTTLETLFLSGNPWKCNCSFLDFAIFLIVFHMDPSDDLNATCVEPTELTGWPITRVGNPLRYMCITHLDHKDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQNTRHKSSEEDEDEAGTRVEVSRRIFQTQTSSVQEFPQLI"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0JN28/", 
                    "id": "A0JN28", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/35430", 
                    "id": "35430", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070902.1", 
        "ac": "NP_001070902.1", 
        "name": "leucine-rich repeat-containing protein 52 precursor; leucine-rich repeat-containing protein 52.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JN28", 
                                "id": "A0JN28", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "voltage-gated potassium channel activity", 
                        "id": "GO:0005249"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JN28", 
                                "id": "A0JN28", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ion channel binding", 
                        "id": "GO:0044325"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099104", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JN28", 
                                "id": "A0JN28", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "potassium channel activator activity", 
                        "id": "GO:0099104"
                    }
                ], 
                "total": 3, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JN28", 
                                "id": "A0JN28", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "voltage-gated potassium channel complex", 
                        "id": "GO:0008076"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903818", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JN28", 
                                "id": "A0JN28", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of voltage-gated potassium channel activity", 
                        "id": "GO:1903818"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022414", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JN28", 
                                "id": "A0JN28", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "reproductive process", 
                        "id": "GO:0022414"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 114, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 112
        }, 
        {
            "end_pos": 133, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 131
        }, 
        {
            "end_pos": 150, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 148
        }, 
        {
            "end_pos": 191, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 189
        }, 
        {
            "end_pos": 213, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 211
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070902.1", 
            "id": "NP_001070902.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:289199", 
            "id": "rno:289199", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000004356", 
            "id": "ENSRNOG00000004356", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/TEYPPDI/", 
            "id": "TEYPPDI", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", 
            "id": "IPR001611", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", 
            "id": "IPR003591", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", 
            "id": "IPR032675", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", 
            "id": "IPR000372", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF13855", 
            "id": "PF13855", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/289199", 
            "id": "289199", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1312014", 
            "id": "1312014", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0JN28", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 35405.0, 
        "chemical_mass": 35405.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0JN28", 
            "name": "Lrrc52; RGD1312014_predicted; RGD1312014.", 
            "locus": {
                "end_pos": 85672014, 
                "start_pos": 85695421, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000004356", 
                        "id": "ENSRNOG00000004356", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}