{
    "uniprot_canonical_ac": "A0A2Z4LIS9-1", 
    "sequence": {
        "header": "sp|A0A2Z4LIS9-1|FXO3B_HUMAN Isoform 1 of Forkhead box protein O3B  OS=Homo sapiens OX=9606 GN=FOXO3B PE=1 SV=1 CANONICAL=A0A2Z4LIS9-1", 
        "length": 290, 
        "sequence": "METDLAEMPEKGVLSSQDSPHFQEKSTEEGEVAALRLTARSQAAAAAAAPGSRSLRGVHVPPPLHPAPAREESARTPAAAGRAAKMAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGSAMAIGGGGGSRTLVSGLLLEDSVRVLAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDRRLTLSQIYEWMVSCVPYFKDKGNSNSSAG"
    }, 
    "uniprot_id": "FXO3B_HUMAN", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [], 
            "uniprotkb": [
                "Forkhead box protein O3B"
            ]
        }, 
        "gene": {
            "refseq": [], 
            "uniprotkb": [
                "FOXO3B"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A2Z4LIS9", 
                    "id": "A0A2Z4LIS9", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Forkhead box protein O3B."
    }, 
    "publication": [
        {
            "title": "A splice junction-targeted CRISPR approach (spJCRISPR) reveals human FOXO3B to be a protein-coding gene.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/29925039", 
            "journal": "Gene", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A2Z4LIS9/publications", 
                    "id": "A0A2Z4LIS9", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Paik J., Santo E.E.", 
            "date": "2018", 
            "pmid": "29925039"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A2Z4LIS9#A0A2Z4LIS9-1", 
            "isoform_ac": "A0A2Z4LIS9-1", 
            "locus": {
                "end_pos": 0, 
                "start_pos": 0, 
                "chromosome": "", 
                "evidence": []
            }, 
            "sequence": {
                "header": "sp|A0A2Z4LIS9-1|FXO3B_HUMAN Isoform 1 of Forkhead box protein O3B  OS=Homo sapiens OX=9606 GN=FOXO3B PE=1 SV=1 CANONICAL=A0A2Z4LIS9-1", 
                "length": 290, 
                "sequence": "METDLAEMPEKGVLSSQDSPHFQEKSTEEGEVAALRLTARSQAAAAAAAPGSRSLRGVHVPPPLHPAPAREESARTPAAAGRAAKMAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGSAMAIGGGGGSRTLVSGLLLEDSVRVLAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDRRLTLSQIYEWMVSCVPYFKDKGNSNSSAG"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A2Z4LIS9#I3L3U3-1", 
            "isoform_ac": "I3L3U3-1", 
            "locus": {
                "end_pos": 18680752, 
                "start_pos": 18681651, 
                "chromosome": "17", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000443457", 
                        "id": "ENST00000443457", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000460736", 
                        "id": "ENSP00000460736", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|I3L3U3-1|FXO3B_HUMAN Computationally mapped isoform of Forkhead box protein O3B  OS=Homo sapiens OX=9606 GN=FOXO3B PE=1 SV=1 CANONICAL=A0A2Z4LIS9-1", 
                "length": 112, 
                "sequence": "METDLAEMPEKGGENCGRVELVAWKDEIPAPEGKTVGSGEVALGWLSPLSWGWMGFLSETEELGMGAPPFPWQLGTQWTLQSYPQNFCLPRILPISKRRAQKREKWLLCASR"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A2Z4LIS9", 
                                "id": "A0A2Z4LIS9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA-binding transcription factor activity", 
                        "id": "GO:0003700"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A2Z4LIS9", 
                                "id": "A0A2Z4LIS9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "sequence-specific DNA binding", 
                        "id": "GO:0043565"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A2Z4LIS9", 
                                "id": "A0A2Z4LIS9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytosol", 
                        "id": "GO:0005829"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 246, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 244
        }, 
        {
            "end_pos": 288, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 286
        }
    ], 
    "crossref": [
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=3822", 
            "id": "3822", 
            "database": "HGNC"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOXO3B", 
            "id": "FOXO3B", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", 
            "id": "IPR036388", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", 
            "id": "IPR036390", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", 
            "id": "IPR001766", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00250", 
            "id": "PF00250", 
            "database": "Pfam"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A2Z4LIS9", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 29900.0, 
        "chemical_mass": 29900.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A2Z4LIS9", 
            "name": "FOXO3B.", 
            "locus": {
                "end_pos": 18670946, 
                "start_pos": 18672873, 
                "chromosome": "17", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000240445", 
                        "id": "ENSG00000240445", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}