{ "uniprot_canonical_ac": "A0A1L1SUI3-1", "sequence": { "header": "tr|A0A1L1SUI3-1|A0A1L1SUI3_MOUSE Isoform 1 of Solute carrier family 37 (glucose-6-phosphate transporter), member 4 OS=Mus musculus OX=10090 GN=Slc37a4 PE=1 SV=1 CANONICAL=A0A1L1SUI3-1", "length": 450, "sequence": "MAAQGYGYYRTVIFAAMFGGYSLYYFNRKTFSFVMPSLVDEIALDKDDLGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVSAFAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILAQSYSWRSTLALSGALCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQDLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVGSIAAGYLSDRAMAKAGLSLYGNPRHGLLLLMMAGMAASMFLFRVTVTSDSPKDAFWTPALHPLAELTGFTEHEIWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVVCGASTVVFFLLRNIRTKMGRVSKKGE" }, "uniprot_id": "A0A1L1SUI3_MOUSE", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [], "uniprotkb": [ "Solute carrier family 37 (glucose-6-phosphate transporter), member 4" ] }, "gene": { "refseq": [], "uniprotkb": [ "Slc37a4" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "recommendedname": { "full": "Solute carrier family 37 (glucose-6-phosphate transporter), member 4." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3#Q9D1F9-1", "isoform_ac": "Q9D1F9-1", "locus": { "end_pos": 44398474, "start_pos": 44402465, "chromosome": "9", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000165839", "id": "ENSMUST00000165839", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000129564", "id": "ENSMUSP00000129564", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|Q9D1F9-1|A0A1L1SUI3_MOUSE Computationally mapped isoform of Solute carrier family 37 (glucose-6-phosphate transporter), member 4 OS=Mus musculus OX=10090 GN=Slc37a4 PE=1 SV=1 CANONICAL=A0A1L1SUI3-1", "length": 429, "sequence": "MAAQGYGYYRTVIFAAMFGGYSLYYFNRKTFSFVMPSLVDEIALDKDDLGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVSAFAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILAQSYSWRSTLALSGALCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQDLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVGSIAAGYLSDRAMAKAGLSLYGNPRHGLLLLMMAGMAASMFLFRVTVTSDSPKIWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVVCGASTVVFFLLRNIRTKMGRVSKKGE" } }, { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3#A0A1L1SUI3-1", "isoform_ac": "A0A1L1SUI3-1", "locus": { "end_pos": 44398474, "start_pos": 44402465, "chromosome": "9", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000213268", "id": "ENSMUST00000213268", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000150753", "id": "ENSMUSP00000150753", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A1L1SUI3-1|A0A1L1SUI3_MOUSE Isoform 1 of Solute carrier family 37 (glucose-6-phosphate transporter), member 4 OS=Mus musculus OX=10090 GN=Slc37a4 PE=1 SV=1 CANONICAL=A0A1L1SUI3-1", "length": 450, "sequence": "MAAQGYGYYRTVIFAAMFGGYSLYYFNRKTFSFVMPSLVDEIALDKDDLGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVSAFAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILAQSYSWRSTLALSGALCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQDLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVGSIAAGYLSDRAMAKAGLSLYGNPRHGLLLLMMAGMAASMFLFRVTVTSDSPKDAFWTPALHPLAELTGFTEHEIWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVVCGASTVVFFLLRNIRTKMGRVSKKGE" } }, { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3#A0A1L1SUV7-1", "isoform_ac": "A0A1L1SUV7-1", "locus": { "end_pos": 44398474, "start_pos": 44399406, "chromosome": "9", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000215121", "id": "ENSMUST00000215121", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000150902", "id": "ENSMUSP00000150902", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A1L1SUV7-1|A0A1L1SUI3_MOUSE Computationally mapped isoform of Solute carrier family 37 (glucose-6-phosphate transporter), member 4 OS=Mus musculus OX=10090 GN=Slc37a4 PE=1 SV=1 CANONICAL=A0A1L1SUI3-1", "length": 102, "sequence": "MAAQGYGYYRTVIFAAMFGGYSLYYFNRKTFSFVMPSLVDEIALDKDDLGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVSA" } }, { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3#A0A1L1SV42-1", "isoform_ac": "A0A1L1SV42-1", "locus": { "end_pos": 44398474, "start_pos": 44399357, "chromosome": "9", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000215001", "id": "ENSMUST00000215001", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000151004", "id": "ENSMUSP00000151004", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A1L1SV42-1|A0A1L1SUI3_MOUSE Computationally mapped isoform of Solute carrier family 37 (glucose-6-phosphate transporter), member 4 OS=Mus musculus OX=10090 GN=Slc37a4 PE=1 SV=1 CANONICAL=A0A1L1SUI3-1", "length": 96, "sequence": "MAAQGYGYYRTVIFAAMFGGYSLYYFNRKTFSFVMPSLVDEIALDKDDLGVLLPAPLRCRAHHKQPVGSLRHQQVCERGSVRSDERPLALLLWAAP" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-70263", "resource": "Reactome", "id": "R-MMU-70263", "name": "Gluconeogenesis" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTY3-1", "protein_name": "Solute carrier family 37 member 4.", "sequence": { "length": 450, "sequence": "MAAQGYGYYRTVIFTAMFGGYSLYYFNRKTFSFVMPSLVDEIALDKDDLGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVTAFAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILAQSYSWRSTLALSGSLCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQDLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVGSIAAGYLSDRAMAKAGLSVYGNPRHSLLLLMMAGMAASMFLFRVTVTSDSPKEAFWTPALHPLAELTGFTEHEIWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICIASTVVFFLLRNIRTKMGRVSKKAE" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/37482", "id": "37482", "database": "MGI" } ], "organism": "Rattus norvegicus", "tax_id": 10116 }, { "uniprot_canonical_ac": "O43826-1", "protein_name": "Glucose-6-phosphate exchanger SLC37A4; Transformation-related gene 19 protein; TRG-19; Glucose-6-phosphate translocase; Glucose-5-phosphate transporter; Solute carrier family 37 member 4.", "sequence": { "length": 429, "sequence": "MAAQGYGYYRTVIFSAMFGGYSLYYFNRKTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTVPVFAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPADVGLRNLDPMPSEGKKGSLKEESTLQELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMSALEVGGLVGSIAAGYLSDRAMAKAGLSNYGNPRHGLLLFMMAGMTVSMYLFRVTVTSDSPKLWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICAASTAAFFLLRNIRTKMGRVSKKAE" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/37482", "id": "37482", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "", "ac": "", "name": "", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061513", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "glucose 6-phosphate:inorganic phosphate antiporter activity", "id": "GO:0061513" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015152", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "glucose-6-phosphate transmembrane transporter activity", "id": "GO:0015152" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005887", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "integral component of plasma membrane", "id": "GO:0005887" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "intracellular membrane-bounded organelle", "id": "GO:0043231" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030176", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "integral component of endoplasmic reticulum membrane", "id": "GO:0030176" } ], "total": 3, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002318", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "myeloid progenitor cell differentiation", "id": "GO:0002318" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006641", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "triglyceride metabolic process", "id": "GO:0006641" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006641", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "triglyceride metabolic process", "id": "GO:0006641" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "glycogen metabolic process", "id": "GO:0005977" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "glycogen metabolic process", "id": "GO:0005977" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "cellular calcium ion homeostasis", "id": "GO:0006874" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "cellular calcium ion homeostasis", "id": "GO:0006874" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043085", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "positive regulation of catalytic activity", "id": "GO:0043085" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "glucose homeostasis", "id": "GO:0042593" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "cholesterol homeostasis", "id": "GO:0042632" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008202", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "steroid metabolic process", "id": "GO:0008202" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001780", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "neutrophil homeostasis", "id": "GO:0001780" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001816", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "cytokine production", "id": "GO:0001816" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015760", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "glucose-6-phosphate transport", "id": "GO:0015760" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030593", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "neutrophil chemotaxis", "id": "GO:0030593" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045730", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "respiratory burst", "id": "GO:0045730" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006089", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "lactate metabolic process", "id": "GO:0006089" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032682", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "negative regulation of chemokine production", "id": "GO:0032682" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035166", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "post-embryonic hemopoiesis", "id": "GO:0035166" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014070", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "response to organic cyclic compound", "id": "GO:0014070" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035435", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "id": "A0A1L1SUI3", "database": "UniProtKB" } ], "name": "phosphate ion transmembrane transport", "id": "GO:0035435" } ], "total": 21, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 377, "annotation": "n_glycosylation_sequon", "start_pos": 375 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006510073.1", "id": "XP_006510073.1", "database": "RefSeq" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-70263", "id": "R-MMU-70263", "database": "Reactome" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "id": "IPR036259", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000849", "id": "IPR000849", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR021159", "id": "IPR021159", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "id": "IPR011701", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "id": "IPR020846", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF07690", "id": "PF07690", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/14385", "id": "14385", "database": "GeneID" }, { "url": "http://www.informatics.jax.org/marker/MGI:1316650", "id": "1316650", "database": "MGI" } ], "expression_disease": [], "uniprot_ac": "A0A1L1SUI3", "disease": [], "mass": { "monoisotopic_mass": 48428.0, "chemical_mass": 48428.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A1L1SUI3", "name": "Slc37a4.", "locus": { "end_pos": 44402968, "start_pos": 44396852, "chromosome": "9", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000032114", "id": "ENSMUSG00000032114", "database": "Ensembl Gene" } ] } } ] }