{
    "uniprot_canonical_ac": "A0A1B0GWH4-1", 
    "sequence": {
        "header": "sp|A0A1B0GWH4-1|HSFX3_HUMAN Isoform 1 of Heat shock transcription factor, X-linked member 3  OS=Homo sapiens OX=9606 GN=HSFX3 PE=3 SV=1 CANONICAL=A0A1B0GWH4-1", 
        "length": 333, 
        "sequence": "MASQNTEQEYEAKLAPSVGGEPTSGGPSGSSPDPNPDSSEVLDRHEDQAMSQDPGSQDNSPPEDRNQRVVNVEDNHNLFRLSFPRKLWTIVEEDTFKSVSWNDDGDAVIIDKDLFQREVLQRKGAERIFKTDSLTSFIRQLNLYGFCKTRPSNSPGNKKMMIYCNSNFQRDKPRLLENIQRKDALRNTAQQATRVPTPKRKNLVATRRSLRIYHINARKEAIKMCQQGAPSVQGPSGTQSFRRSGMWSKKSATRHPLGNGPPQEPNGPSWEGTSGNVTFTSSATTWMEGTGILSSLVYSDNGSVMSLYNICYYALLASLSVMSPNEPSDDEEE"
    }, 
    "uniprot_id": "HSFX3_HUMAN", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "heat shock transcription factor, X-linked member 3", 
                "heat shock transcription factor, X-linked-like"
            ], 
            "uniprotkb": [
                "Heat shock transcription factor, X-linked member 3"
            ]
        }, 
        "gene": {
            "refseq": [
                "HSFX3"
            ], 
            "uniprotkb": [
                "HSFX3"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", 
                    "id": "A0A1B0GWH4", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Heat shock transcription factor, X-linked member 3."
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4#A0A1B0GWH4-1", 
            "isoform_ac": "A0A1B0GWH4-1", 
            "locus": {
                "end_pos": 149548395, 
                "start_pos": 149549852, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000431993", 
                        "id": "ENST00000431993", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000490928", 
                        "id": "ENSP00000490928", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A0A1B0GWH4-1|HSFX3_HUMAN Isoform 1 of Heat shock transcription factor, X-linked member 3  OS=Homo sapiens OX=9606 GN=HSFX3 PE=3 SV=1 CANONICAL=A0A1B0GWH4-1", 
                "length": 333, 
                "sequence": "MASQNTEQEYEAKLAPSVGGEPTSGGPSGSSPDPNPDSSEVLDRHEDQAMSQDPGSQDNSPPEDRNQRVVNVEDNHNLFRLSFPRKLWTIVEEDTFKSVSWNDDGDAVIIDKDLFQREVLQRKGAERIFKTDSLTSFIRQLNLYGFCKTRPSNSPGNKKMMIYCNSNFQRDKPRLLENIQRKDALRNTAQQATRVPTPKRKNLVATRRSLRIYHINARKEAIKMCQQGAPSVQGPSGTQSFRRSGMWSKKSATRHPLGNGPPQEPNGPSWEGTSGNVTFTSSATTWMEGTGILSSLVYSDNGSVMSLYNICYYALLASLSVMSPNEPSDDEEE"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:101928917", 
            "resource": "KEGG Pathway", 
            "id": "hsa:101928917", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001310008.1", 
        "ac": "NP_001310008.1", 
        "name": "heat shock transcription factor, X-linked member 3; heat shock transcription factor, X-linked-like.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", 
                                "id": "A0A1B0GWH4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA-binding transcription factor activity", 
                        "id": "GO:0003700"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", 
                                "id": "A0A1B0GWH4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "RNA polymerase II proximal promoter sequence-specific DNA binding", 
                        "id": "GO:0000978"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", 
                                "id": "A0A1B0GWH4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "sequence-specific DNA binding", 
                        "id": "GO:0043565"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", 
                                "id": "A0A1B0GWH4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", 
                        "id": "GO:0000981"
                    }
                ], 
                "total": 4, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", 
                                "id": "A0A1B0GWH4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000790", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", 
                                "id": "A0A1B0GWH4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nuclear chromatin", 
                        "id": "GO:0000790"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", 
                                "id": "A0A1B0GWH4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cellular response to heat", 
                        "id": "GO:0034605"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061408", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", 
                                "id": "A0A1B0GWH4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of transcription from RNA polymerase II promoter in response to heat stress", 
                        "id": "GO:0061408"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 278, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 276
        }, 
        {
            "end_pos": 303, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 301
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001310008.1", 
            "id": "NP_001310008.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=52395", 
            "id": "52395", 
            "database": "HGNC"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A0A1B0GWH4", 
            "id": "A0A1B0GWH4", 
            "database": "PHAROS"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A0A1B0GWH4", 
            "id": "NX_A0A1B0GWH4", 
            "database": "neXtProt"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=HSFX3", 
            "id": "HSFX3", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:101928917", 
            "id": "hsa:101928917", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/SATAWME/", 
            "id": "SATAWME", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", 
            "id": "IPR036388", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", 
            "id": "IPR036390", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027725", 
            "id": "IPR027725", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", 
            "id": "IPR000232", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00447", 
            "id": "PF00447", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", 
            "id": "PTHR10015", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A0A1B0GWH4", 
            "id": "PR_A0A1B0GWH4", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/101928917", 
            "id": "101928917", 
            "database": "GeneID"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A1B0GWH4", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 37128.0, 
        "chemical_mass": 37128.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", 
            "name": "HSFX3.", 
            "locus": {
                "end_pos": 149548210, 
                "start_pos": 149549932, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000283697", 
                        "id": "ENSG00000283697", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}