{
    "uniprot_canonical_ac": "A0A1B0GUS4-1", 
    "sequence": {
        "header": "sp|A0A1B0GUS4-1|UB2L5_HUMAN Isoform 1 of Ubiquitin-conjugating enzyme E2 L5  OS=Homo sapiens OX=9606 GN=UBE2L5 PE=2 SV=1 CANONICAL=A0A1B0GUS4-1", 
        "length": 154, 
        "sequence": "MAASRRLMKELEEIRKCGMENFRNIQVDEANLLTWQGLIVPDNPPYNKGAFRIEINFPAEYPFKPPRITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSNDRKKFCKNAEEFTKKYGEKRPVD"
    }, 
    "uniprot_id": "UB2L5_HUMAN", 
    "enzyme_annotation": [
        {
            "ec": "2.3.2.23", 
            "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine."
        }, 
        {
            "ec": "2.3.2.23", 
            "activity": ""
        }
    ], 
    "synonyms": {
        "protein": {
            "refseq": [], 
            "uniprotkb": [
                "Ubiquitin-conjugating enzyme E2 L5", 
                "2.3.2.23", 
                "Ubiquitin-protein ligase L5"
            ]
        }, 
        "gene": {
            "refseq": [], 
            "uniprotkb": [
                "UBE2L5"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4", 
                    "id": "A0A1B0GUS4", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "Ubiquitin-conjugating enzyme E2 L5; 2.3.2.23; Ubiquitin-protein ligase L5."
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4#A0A1B0GUS4-1", 
            "isoform_ac": "A0A1B0GUS4-1", 
            "locus": {
                "end_pos": 30427991, 
                "start_pos": 30428452, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000436446", 
                        "id": "ENST00000436446", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000490834", 
                        "id": "ENSP00000490834", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A0A1B0GUS4-1|UB2L5_HUMAN Isoform 1 of Ubiquitin-conjugating enzyme E2 L5  OS=Homo sapiens OX=9606 GN=UBE2L5 PE=2 SV=1 CANONICAL=A0A1B0GUS4-1", 
                "length": 154, 
                "sequence": "MAASRRLMKELEEIRKCGMENFRNIQVDEANLLTWQGLIVPDNPPYNKGAFRIEINFPAEYPFKPPRITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSNDRKKFCKNAEEFTKKYGEKRPVD"
            }
        }
    ], 
    "pathway": [], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4#function", 
            "annotation": "Catalyzes the covalent attachment of ubiquitin to other proteins.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4#function", 
                    "id": "A0A1B0GUS4", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4", 
                                "id": "A0A1B0GUS4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ubiquitin protein ligase binding", 
                        "id": "GO:0031625"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4", 
                                "id": "A0A1B0GUS4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ubiquitin conjugating enzyme activity", 
                        "id": "GO:0061631"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4", 
                                "id": "A0A1B0GUS4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ATP binding", 
                        "id": "GO:0005524"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4", 
                                "id": "A0A1B0GUS4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ligase activity", 
                        "id": "GO:0016874"
                    }
                ], 
                "total": 4, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4", 
                                "id": "A0A1B0GUS4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ubiquitin ligase complex", 
                        "id": "GO:0000151"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4", 
                                "id": "A0A1B0GUS4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "protein K11-linked ubiquitination", 
                        "id": "GO:0070979"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4", 
                                "id": "A0A1B0GUS4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ubiquitin-dependent protein catabolic process", 
                        "id": "GO:0006511"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=13477", 
            "id": "13477", 
            "database": "HGNC"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A0A1B0GUS4", 
            "id": "NX_A0A1B0GUS4", 
            "database": "neXtProt"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=UBE2L5", 
            "id": "UBE2L5", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/DCPPYDK/", 
            "id": "DCPPYDK", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00195", 
            "id": "cd00195", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", 
            "id": "IPR000608", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", 
            "id": "IPR016135", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023313", 
            "id": "IPR023313", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00179", 
            "id": "PF00179", 
            "database": "Pfam"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A0A1B0GUS4", 
            "id": "PR_A0A1B0GUS4", 
            "database": "PRO"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A1B0GUS4", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 17875.0, 
        "chemical_mass": 17875.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GUS4", 
            "name": "UBE2L5.", 
            "locus": {
                "end_pos": 30428616, 
                "start_pos": 30422488, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000236444", 
                        "id": "ENSG00000236444", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}