{ "uniprot_canonical_ac": "A0A182DWI7-1", "sequence": { "header": "tr|A0A182DWI7-1|A0A182DWI7_RAT Isoform 1 of Deacetylase sirtuin-type domain-containing protein OS=Rattus norvegicus OX=10116 GN= PE=4 SV=1 CANONICAL=A0A182DWI7-1", "length": 730, "sequence": "MWLLGIELRTSGRVVGCSLPLSHLSSPTDFIFVLCAFVLDFEVGSPFSPGWSWNYFVRSGWFTTSVPSSCWNYRCVWVYAFLGFVFVSKTCVSLYKPNRPQSTWDCRYGQQAAGDCLSSSFLISLTDNLLLADEIITNGFHSCESDDDDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELVHLSELPPTPLHISEDSSSPERTVPQDSSVIATLVDQTIKNKVDDLEVSEPKSCVEEKSQEVQTYRNVESINVENPDFKAVGSSTGDKNERTSVAETVRKCWPNRLAKEQISKRLDGNQYLFVPPNRYIFHGAEVYSDSEDDALSSSSCGSNSDSGTCQSPSLEEPLEDESEIEEFYNGLEDDADRPECAGGSGADGGDQEAVNEAIAMKQELTDVNCTPDKSEHY" }, "uniprot_id": "A0A182DWI7_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [], "uniprotkb": [ "Deacetylase sirtuin-type domain-containing protein" ] }, "gene": { "refseq": [], "uniprotkb": [] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Deacetylase sirtuin-type domain-containing protein." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7#A0A182DWI7-1", "isoform_ac": "A0A182DWI7-1", "locus": { "end_pos": 26833559, "start_pos": 26852001, "chromosome": "20", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000078739", "id": "ENSRNOT00000078739", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000070943", "id": "ENSRNOP00000070943", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A182DWI7-1|A0A182DWI7_RAT Isoform 1 of Deacetylase sirtuin-type domain-containing protein OS=Rattus norvegicus OX=10116 GN= PE=4 SV=1 CANONICAL=A0A182DWI7-1", "length": 730, "sequence": "MWLLGIELRTSGRVVGCSLPLSHLSSPTDFIFVLCAFVLDFEVGSPFSPGWSWNYFVRSGWFTTSVPSSCWNYRCVWVYAFLGFVFVSKTCVSLYKPNRPQSTWDCRYGQQAAGDCLSSSFLISLTDNLLLADEIITNGFHSCESDDDDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELVHLSELPPTPLHISEDSSSPERTVPQDSSVIATLVDQTIKNKVDDLEVSEPKSCVEEKSQEVQTYRNVESINVENPDFKAVGSSTGDKNERTSVAETVRKCWPNRLAKEQISKRLDGNQYLFVPPNRYIFHGAEVYSDSEDDALSSSSCGSNSDSGTCQSPSLEEPLEDESEIEEFYNGLEDDADRPECAGGSGADGGDQEAVNEAIAMKQELTDVNCTPDKSEHY" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3371453", "resource": "Reactome", "id": "R-RNO-3371453", "name": "Regulation of HSF1-mediated heat shock response" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9617629", "resource": "Reactome", "id": "R-RNO-9617629", "name": "Regulation of FOXO transcriptional activity by acetylation" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-427359", "resource": "Reactome", "id": "R-RNO-427359", "name": "SIRT1 negatively regulates rRNA expression" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q96EB6-1", "protein_name": "NAD-dependent protein deacetylase sirtuin-1; hSIRT1; 2.3.1.286; SIR2-like protein 1; hSIR2; Regulatory protein SIR2 homolog 1.", "sequence": { "length": 747, "sequence": "MADEAALALQPGGSPSAAGADREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREVPAAARGCPGAAAAALWREAEAEAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADNLYDEDDDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNKS" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A0A182DWI7/", "id": "A0A182DWI7", "database": "OMA" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "", "ac": "", "name": "", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "transcription corepressor activity", "id": "GO:0003714" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070403", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "NAD+ binding", "id": "GO:0070403" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "p53 binding", "id": "GO:0002039" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017136", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "NAD-dependent histone deacetylase activity", "id": "GO:0017136" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990254", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "keratin filament binding", "id": "GO:1990254" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "identical protein binding", "id": "GO:0042802" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008022", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "protein C-terminus binding", "id": "GO:0008022" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051019", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "mitogen-activated protein kinase binding", "id": "GO:0051019" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "histone binding", "id": "GO:0042393" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035257", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "nuclear hormone receptor binding", "id": "GO:0035257" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043425", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "bHLH transcription factor binding", "id": "GO:0043425" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043398", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "HLH domain binding", "id": "GO:0043398" } ], "total": 12, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "nucleoplasm", "id": "GO:0005654" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005719", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "nuclear euchromatin", "id": "GO:0005719" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005720", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "nuclear heterochromatin", "id": "GO:0005720" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033553", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "rDNA heterochromatin", "id": "GO:0033553" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "nuclear inner membrane", "id": "GO:0005637" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "nucleolus", "id": "GO:0005730" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "mitochondrion", "id": "GO:0005739" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "cytosol", "id": "GO:0005829" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "PML body", "id": "GO:0016605" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "ESC/E(Z) complex", "id": "GO:0035098" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005677", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "chromatin silencing complex", "id": "GO:0005677" } ], "total": 13, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "negative regulation of transcription, DNA-templated", "id": "GO:0045892" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070932", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "histone H3 deacetylation", "id": "GO:0070932" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051097", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "negative regulation of helicase activity", "id": "GO:0051097" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090400", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "stress-induced premature senescence", "id": "GO:0090400" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000720", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "pyrimidine dimer repair by nucleotide-excision repair", "id": "GO:0000720" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000480", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "negative regulation of cAMP-dependent protein kinase activity", "id": "GO:2000480" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031937", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "positive regulation of chromatin silencing", "id": "GO:0031937" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "angiogenesis", "id": "GO:0001525" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043280", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "positive regulation of cysteine-type endopeptidase activity involved in apoptotic process", "id": "GO:0043280" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "positive regulation of angiogenesis", "id": "GO:0045766" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "cellular response to hypoxia", "id": "GO:0071456" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "regulation of mitotic cell cycle", "id": "GO:0007346" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032088", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "negative regulation of NF-kappaB transcription factor activity", "id": "GO:0032088" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042771", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:0042771" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001938", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "positive regulation of endothelial cell proliferation", "id": "GO:0001938" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "negative regulation of cell growth", "id": "GO:0030308" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "negative regulation of I-kappaB kinase/NF-kappaB signaling", "id": "GO:0043124" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "positive regulation of DNA repair", "id": "GO:0045739" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "cellular response to hydrogen peroxide", "id": "GO:0070301" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000773", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "negative regulation of cellular senescence", "id": "GO:2000773" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "protein ubiquitination", "id": "GO:0016567" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "negative regulation of TOR signaling", "id": "GO:0032007" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000481", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "positive regulation of cAMP-dependent protein kinase activity", "id": "GO:2000481" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "positive regulation of macroautophagy", "id": "GO:0016239" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000012", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "single strand break repair", "id": "GO:0000012" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043536", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "positive regulation of blood vessel endothelial cell migration", "id": "GO:0043536" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046628", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A182DWI7", "id": "A0A182DWI7", "database": "UniProtKB" } ], "name": "positive regulation of insulin receptor signaling pathway", 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