{
    "uniprot_canonical_ac": "A0A0G2QC01-1", 
    "sequence": {
        "header": "tr|A0A0G2QC01-1|A0A0G2QC01_RAT Isoform 1 of RAR-related orphan receptor C  OS=Rattus norvegicus OX=10116 GN=Rorc PE=3 SV=1 CANONICAL=A0A0G2QC01-1", 
        "length": 487, 
        "sequence": "MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCNVAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQQQQREQVAKTPPAGSHGADTLTYTLGVPDGQLPLGASPDLPEASACPPGLLRASGSGPPYSNTLAKTEVQGASCHLEYSPERGKAEGRDSIYSTDGQLTLGRRGLQLGEPEQGSDSHCSPSFCSAPEAPYASLTDIEYLVQNVCKSYRETCQLRLEDLLRQRTNLFSREEVTSYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIILLKAGAMEVVLVRMCRAYNANNHTVFFEGKYGGVELFRALGCSELISSIFDFSHFLSALCFSEDEIALYTALVLINANRPGLQEKRRVEHLQYNLELAFHHHLCKTHRQGLLAKLPPKGKLRSLCSQHVEKLQDFQHLHPIVVQAAFPPLYKELFSTDIESSEGLSK"
    }, 
    "uniprot_id": "A0A0G2QC01_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "nuclear receptor ROR-gamma isoform X2"
            ], 
            "uniprotkb": [
                "RAR-related orphan receptor C"
            ]
        }, 
        "gene": {
            "refseq": [
                "Rorc"
            ], 
            "uniprotkb": [
                "Rorc"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                    "id": "A0A0G2QC01", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "RAR-related orphan receptor C."
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2QC01#A0A0G2QC01-1", 
            "isoform_ac": "A0A0G2QC01-1", 
            "locus": {
                "end_pos": 195617220, 
                "start_pos": 195636319, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000067042", 
                        "id": "ENSRNOT00000067042", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000058884", 
                        "id": "ENSRNOP00000058884", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2QC01-1|A0A0G2QC01_RAT Isoform 1 of RAR-related orphan receptor C  OS=Rattus norvegicus OX=10116 GN=Rorc PE=3 SV=1 CANONICAL=A0A0G2QC01-1", 
                "length": 487, 
                "sequence": "MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCNVAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQQQQREQVAKTPPAGSHGADTLTYTLGVPDGQLPLGASPDLPEASACPPGLLRASGSGPPYSNTLAKTEVQGASCHLEYSPERGKAEGRDSIYSTDGQLTLGRRGLQLGEPEQGSDSHCSPSFCSAPEAPYASLTDIEYLVQNVCKSYRETCQLRLEDLLRQRTNLFSREEVTSYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIILLKAGAMEVVLVRMCRAYNANNHTVFFEGKYGGVELFRALGCSELISSIFDFSHFLSALCFSEDEIALYTALVLINANRPGLQEKRRVEHLQYNLELAFHHHLCKTHRQGLLAKLPPKGKLRSLCSQHVEKLQDFQHLHPIVVQAAFPPLYKELFSTDIESSEGLSK"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-383280", 
            "resource": "Reactome", 
            "id": "R-RNO-383280", 
            "name": "Nuclear Receptor transcription pathway"
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "P51449-1", 
            "protein_name": "Nuclear receptor ROR-gamma; RAR-related orphan receptor C; Retinoid-related orphan receptor-gamma; Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3.", 
            "sequence": {
                "length": 518, 
                "sequence": "MDRAPQRQHRASRELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSTETESPVGLSK"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2QC01/", 
                    "id": "A0A0G2QC01", 
                    "database": "OMA"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008759561.1", 
        "ac": "XP_008759561.1", 
        "name": "nuclear receptor ROR-gamma isoform X2.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008142", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                                "id": "A0A0G2QC01", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "oxysterol binding", 
                        "id": "GO:0008142"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001223", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                                "id": "A0A0G2QC01", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "transcription coactivator binding", 
                        "id": "GO:0001223"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003707", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                                "id": "A0A0G2QC01", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "steroid hormone receptor activity", 
                        "id": "GO:0003707"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                                "id": "A0A0G2QC01", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", 
                        "id": "GO:0001227"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                                "id": "A0A0G2QC01", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "RNA polymerase II proximal promoter sequence-specific DNA binding", 
                        "id": "GO:0000978"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                                "id": "A0A0G2QC01", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nuclear receptor activity", 
                        "id": "GO:0004879"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                                "id": "A0A0G2QC01", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "zinc ion binding", 
                        "id": "GO:0008270"
                    }
                ], 
                "total": 7, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                                "id": "A0A0G2QC01", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nuclear body", 
                        "id": "GO:0016604"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                                "id": "A0A0G2QC01", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "circadian rhythm", 
                        "id": "GO:0007623"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036315", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
                                "id": "A0A0G2QC01", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cellular response to sterol", 
                        "id": "GO:0036315"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 344, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 342
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008759561.1", 
            "id": "XP_008759561.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-383280", 
            "id": "R-RNO-383280", 
            "database": "Reactome"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000020836", 
            "id": "ENSRNOG00000020836", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/QGPDSYC/", 
            "id": "QGPDSYC", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", 
            "id": "IPR000536", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", 
            "id": "IPR001628", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", 
            "id": "IPR035500", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", 
            "id": "IPR001723", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003079", 
            "id": "IPR003079", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", 
            "id": "IPR013088", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00104", 
            "id": "PF00104", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00105", 
            "id": "PF00105", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/368158", 
            "id": "368158", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1595785", 
            "id": "1595785", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2QC01", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 54684.0, 
        "chemical_mass": 54684.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2QC01", 
            "name": "Rorc.", 
            "locus": {
                "end_pos": 195637630, 
                "start_pos": 195617021, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000020836", 
                        "id": "ENSRNOG00000020836", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}