{
    "uniprot_canonical_ac": "A0A0G2KAX1-1", 
    "sequence": {
        "header": "tr|A0A0G2KAX1-1|A0A0G2KAX1_RAT Isoform 1 of EEF1A lysine methyltransferase 1  OS=Rattus norvegicus OX=10116 GN=Eef1akmt1 PE=3 SV=1 CANONICAL=A0A0G2KAX1-1", 
        "length": 224, 
        "sequence": "MCQWSQTPCEMSDSEDDDIPQLSSHTLAALQEFYAEQKQTINPGGDDKYNVGVIEENWQLSQFWYSQDTALRLAQEAINAVGEGGRIACVSAPSVYQKLRELRREDISVYIFEYDRRFAIYGDEFIFYDYNNPLDLPEGVAPHSFDIVVADPPYLSEECLRKTSETIQFLTQGKILLCTGAIMEEQAAQLLGVKVCKFIPEHSRNLANEFRCYTNYDSGLDCET"
    }, 
    "uniprot_id": "A0A0G2KAX1_RAT", 
    "enzyme_annotation": [
        {
            "ec": "2.1.1.-", 
            "activity": ""
        }
    ], 
    "synonyms": {
        "protein": {
            "refseq": [
                "protein-lysine N-methyltransferase N6AMT2 isoform X2"
            ], 
            "uniprotkb": [
                "EEF1A lysine methyltransferase 1", 
                "2.1.1.-", 
                "N(6)-adenine-specific DNA methyltransferase 2", 
                "Protein-lysine N-methyltransferase N6AMT2"
            ]
        }, 
        "gene": {
            "refseq": [
                "Eef1akmt1", 
                "N6amt2", 
                "RGD1306762"
            ], 
            "uniprotkb": [
                "Eef1akmt1", 
                "EEF1AKMT1", 
                "N6AMT2", 
                "N6amt2", 
                "RGD1306762"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2KAX1", 
                    "id": "A0A0G2KAX1", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "EEF1A lysine methyltransferase 1; 2.1.1.-; N(6)-adenine-specific DNA methyltransferase 2; Protein-lysine N-methyltransferase N6AMT2."
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAX1#A0A096MK28-1", 
            "isoform_ac": "A0A096MK28-1", 
            "locus": {
                "end_pos": 37822829, 
                "start_pos": 37825194, 
                "chromosome": "15", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000075884", 
                        "id": "ENSRNOT00000075884", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068357", 
                        "id": "ENSRNOP00000068357", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A096MK28-1|A0A0G2KAX1_RAT Computationally mapped isoform of EEF1A lysine methyltransferase 1  OS=Rattus norvegicus OX=10116 GN=Eef1akmt1 PE=3 SV=1 CANONICAL=A0A0G2KAX1-1", 
                "length": 58, 
                "sequence": "MSDSEDDDIPQLSSHTLAALQEFYAEQKQTINPGGDDKYNVGVIEENWINLPHTRHRI"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAX1#A0A0G2KAX1-1", 
            "isoform_ac": "A0A0G2KAX1-1", 
            "locus": {
                "end_pos": 37813265, 
                "start_pos": 37830096, 
                "chromosome": "15", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000091562", 
                        "id": "ENSRNOT00000091562", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000075559", 
                        "id": "ENSRNOP00000075559", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2KAX1-1|A0A0G2KAX1_RAT Isoform 1 of EEF1A lysine methyltransferase 1  OS=Rattus norvegicus OX=10116 GN=Eef1akmt1 PE=3 SV=1 CANONICAL=A0A0G2KAX1-1", 
                "length": 224, 
                "sequence": "MCQWSQTPCEMSDSEDDDIPQLSSHTLAALQEFYAEQKQTINPGGDDKYNVGVIEENWQLSQFWYSQDTALRLAQEAINAVGEGGRIACVSAPSVYQKLRELRREDISVYIFEYDRRFAIYGDEFIFYDYNNPLDLPEGVAPHSFDIVVADPPYLSEECLRKTSETIQFLTQGKILLCTGAIMEEQAAQLLGVKVCKFIPEHSRNLANEFRCYTNYDSGLDCET"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAX1#B5DEG5-1", 
            "isoform_ac": "B5DEG5-1", 
            "locus": {
                "end_pos": 37813265, 
                "start_pos": 37825194, 
                "chromosome": "15", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000064702", 
                        "id": "ENSRNOT00000064702", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000059566", 
                        "id": "ENSRNOP00000059566", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|B5DEG5-1|A0A0G2KAX1_RAT Computationally mapped isoform of EEF1A lysine methyltransferase 1  OS=Rattus norvegicus OX=10116 GN=Eef1akmt1 PE=3 SV=1 CANONICAL=A0A0G2KAX1-1", 
                "length": 214, 
                "sequence": "MSDSEDDDIPQLSSHTLAALQEFYAEQKQTINPGGDDKYNVGVIEENWQLSQFWYSQDTALRLAQEAINAVGEGGRIACVSAPSVYQKLRELRREDISVYIFEYDRRFAIYGDEFIFYDYNNPLDLPEGVAPHSFDIVVADPPYLSEECLRKTSETIQFLTQGKILLCTGAIMEEQAAQLLGVKVCKFIPEHSRNLANEFRCYTNYDSGLDCET"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8876725", 
            "resource": "Reactome", 
            "id": "R-RNO-8876725", 
            "name": "Protein methylation"
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAX1#function", 
            "annotation": "Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2KAX1#function", 
                    "id": "A0A0G2KAX1", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9CY45-1", 
            "protein_name": "EEF1A lysine methyltransferase 1; 2.1.1.-; Protein-lysine N-methyltransferase N6amt2; N(6)-adenine-specific DNA methyltransferase 2.", 
            "sequence": {
                "length": 214, 
                "sequence": "MSESEDDDIPQLSSHTLAALQEFYAEQKQSVNPRGDDKYNVGVIEENWQLSQFWYSQDTALRLAREAIDAAGEGGRIACVSAPSVYQKLRELCREDSSVYIFEYDRRFAIYGDEFIFYDYNHPLELPERIAAHSFDLVVADPPYLSEECLRKTSETIQFLTRGKILLCTGAIMEEQAAQLLGVKMCKFIPEHSRNLANEFRCYTNYDSGLDCEA"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/5952", 
                    "id": "5952", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q8WVE0-1", 
            "protein_name": "EEF1A lysine methyltransferase 1; 2.1.1.-; N(6)-adenine-specific DNA methyltransferase 2; Protein-lysine N-methyltransferase N6AMT2.", 
            "sequence": {
                "length": 214, 
                "sequence": "MSDLEDDETPQLSAHALAALQEFYAEQKQQIEPGEDDKYNIGIIEENWQLSQFWYSQETALQLAQEAIAAVGEGGRIACVSAPSVYQKLRELCRENFSIYIFEYDKRFAMYGEEFIFYDYNNPLDLPERIAAHSFDIVIADPPYLSEECLRKTSETVKYLTRGKILLCTGAIMEEQAAELLGVKMCTFVPRHTRNLANEFRCYVNYDSGLDCGI"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/5952", 
                    "id": "5952", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2KAX1/", 
                    "id": "A0A0G2KAX1", 
                    "database": "OMA"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006252123.1", 
        "ac": "XP_006252123.1", 
        "name": "protein-lysine N-methyltransferase N6AMT2 isoform X2.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAX1", 
                                "id": "A0A0G2KAX1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleic acid binding", 
                        "id": "GO:0003676"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAX1", 
                                "id": "A0A0G2KAX1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "protein-lysine N-methyltransferase activity", 
                        "id": "GO:0016279"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAX1", 
                                "id": "A0A0G2KAX1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006252123.1", 
            "id": "XP_006252123.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8876725", 
            "id": "R-RNO-8876725", 
            "database": "Reactome"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000009849", 
            "id": "ENSRNOG00000009849", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/VIEENWQ/", 
            "id": "VIEENWQ", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", 
            "id": "IPR029063", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002052", 
            "id": "IPR002052", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019369", 
            "id": "IPR019369", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041370", 
            "id": "IPR041370", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF10237", 
            "id": "PF10237", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13200", 
            "id": "PTHR13200", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/290279", 
            "id": "290279", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306762", 
            "id": "1306762", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2KAX1", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 25532.0, 
        "chemical_mass": 25532.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAX1", 
            "name": "Eef1akmt1; EEF1AKMT1; N6AMT2; N6amt2; RGD1306762.", 
            "locus": {
                "end_pos": 37813115, 
                "start_pos": 37831031, 
                "chromosome": "15", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000009849", 
                        "id": "ENSRNOG00000009849", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}