{
    "uniprot_canonical_ac": "A0A0G2KAW9-1", 
    "sequence": {
        "header": "tr|A0A0G2KAW9-1|A0A0G2KAW9_RAT Isoform 1 of Centromere protein B  OS=Rattus norvegicus OX=10116 GN=Cenpb PE=1 SV=1 CANONICAL=A0A0G2KAW9-1", 
        "length": 603, 
        "sequence": "MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWLDRFRRRHGVVACSGVTRSRARSSAPRAPAAPAGPATVPSEGSGGSTPSWRTREEQPPSVAEGYASQDVFSATETSLWYDFLSDQASGLWGGDGPARQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQGGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLAAQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLGLVEALHFVAAAWQAVEPSDIATCFREAGFGGGLNATITTSFKSEGEEEEEEEEEEEEEEEEGEGEEEEEEEEEGEEEEGGEGEEVGEEEEEVEEEGEVDDSDEEEEEESSSEGLEAEDWAQGVVEASGGFGGYSVQEEAQCPTLHFLEGGEDSDSDSDEEEEDEEEDEEDEEDEDDDEDGDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS"
    }, 
    "uniprot_id": "A0A0G2KAW9_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "major centromere autoantigen B"
            ], 
            "uniprotkb": [
                "Centromere protein B"
            ]
        }, 
        "gene": {
            "refseq": [
                "Cenpb"
            ], 
            "uniprotkb": [
                "Cenpb"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2KAW9", 
                    "id": "A0A0G2KAW9", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Centromere protein B."
    }, 
    "publication": [
        {
            "title": "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/16641100", 
            "journal": "Proc. Natl. Acad. Sci. U.S.A.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2KAW9/publications", 
                    "id": "A0A0G2KAW9", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Wang G., Shen R.F., Knepper M.A., Shen R.-F., Hoffert J.D., Pisitkun T.", 
            "date": "2006", 
            "pmid": "16641100"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAW9#A0A0G2KAW9-1", 
            "isoform_ac": "A0A0G2KAW9-1", 
            "locus": {
                "end_pos": 123721688, 
                "start_pos": 123723496, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000080351", 
                        "id": "ENSRNOT00000080351", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000075557", 
                        "id": "ENSRNOP00000075557", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2KAW9-1|A0A0G2KAW9_RAT Isoform 1 of Centromere protein B  OS=Rattus norvegicus OX=10116 GN=Cenpb PE=1 SV=1 CANONICAL=A0A0G2KAW9-1", 
                "length": 603, 
                "sequence": "MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWLDRFRRRHGVVACSGVTRSRARSSAPRAPAAPAGPATVPSEGSGGSTPSWRTREEQPPSVAEGYASQDVFSATETSLWYDFLSDQASGLWGGDGPARQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQGGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLAAQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLGLVEALHFVAAAWQAVEPSDIATCFREAGFGGGLNATITTSFKSEGEEEEEEEEEEEEEEEEGEGEEEEEEEEEGEEEEGGEGEEVGEEEEEVEEEGEVDDSDEEEEEESSSEGLEAEDWAQGVVEASGGFGGYSVQEEAQCPTLHFLEGGEDSDSDSDEEEEDEEEDEEDEEDEDDDEDGDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:362217", 
            "resource": "KEGG Pathway", 
            "id": "rno:362217", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "P27790-1", 
            "protein_name": "Major centromere autoantigen B; Centromere protein B; CENP-B.", 
            "sequence": {
                "length": 599, 
                "sequence": "MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWLDRFRRRHGVVACSGVTRSRARSSAPRAPAAPAGPATVPSEGSGGSTPGWHTREEQPPSVAEGYASQDVFSATETSLWYDFLSDQASGLWGGDGPARQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQGGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLAAQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLGLVEALHFVAAAWQAVEPSDIATCFREAGFGGGLNATITTSFKSEGEEEEEEEEEEEEEEEEEGEGEEEEEEEEEGEEEGGEGEEEGEEEVEEEGEVDDSDEEEEESSSEGLEAEDWAQGVVEASGGFGGYSVQEEAQFPTLHFLEGGEDSDSDSDEEEDDEEEDEEDEDEEDDEDGDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2KAW9/", 
                    "id": "A0A0G2KAW9", 
                    "database": "OMA"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "P07199-1", 
            "protein_name": "Major centromere autoantigen B; Centromere protein B; CENP-B.", 
            "sequence": {
                "length": 599, 
                "sequence": "MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLAAQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2KAW9/", 
                    "id": "A0A0G2KAW9", 
                    "database": "OMA"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001081194.1", 
        "ac": "XP_001081194.1", 
        "name": "major centromere autoantigen B.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAW9", 
                                "id": "A0A0G2KAW9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "chromatin binding", 
                        "id": "GO:0003682"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003696", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAW9", 
                                "id": "A0A0G2KAW9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "satellite DNA binding", 
                        "id": "GO:0003696"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAW9", 
                                "id": "A0A0G2KAW9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nuclear body", 
                        "id": "GO:0016604"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000780", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAW9", 
                                "id": "A0A0G2KAW9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "condensed nuclear chromosome, centromeric region", 
                        "id": "GO:0000780"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031618", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAW9", 
                                "id": "A0A0G2KAW9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nuclear pericentric heterochromatin", 
                        "id": "GO:0031618"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 396, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 394
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001081194.1", 
            "id": "XP_001081194.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:362217", 
            "id": "rno:362217", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000057284", 
            "id": "ENSRNOG00000057284", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/PVKGIIL/", 
            "id": "PVKGIIL", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", 
            "id": "IPR009057", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR004875", 
            "id": "IPR004875", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015115", 
            "id": "IPR015115", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033062", 
            "id": "IPR033062", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR034882", 
            "id": "IPR034882", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006600", 
            "id": "IPR006600", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007889", 
            "id": "IPR007889", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF03184", 
            "id": "PF03184", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF09026", 
            "id": "PF09026", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF03221", 
            "id": "PF03221", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF04218", 
            "id": "PF04218", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303:SF25", 
            "id": "PTHR19303:SF25", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/362217", 
            "id": "362217", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1304794", 
            "id": "1304794", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2KAW9", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 65873.0, 
        "chemical_mass": 65873.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAW9", 
            "name": "Cenpb.", 
            "locus": {
                "end_pos": 123721486, 
                "start_pos": 123723524, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000057284", 
                        "id": "ENSRNOG00000057284", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}