{ "uniprot_canonical_ac": "A0A0G2KA92-1", "sequence": { "header": "tr|A0A0G2KA92-1|A0A0G2KA92_RAT Isoform 1 of Chromodomain helicase DNA-binding protein 2 OS=Rattus norvegicus OX=10116 GN=Chd2 PE=1 SV=1 CANONICAL=A0A0G2KA92-1", "length": 1840, "sequence": "MAHKPREEHLSLSPCIFTWYQTFSQLTFEEEKLSHSASEEASASDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDDQEQGSSAESEAEQKKVKARRPIPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAVEANGDPSGDFDTEREEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEVNVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIRAPEDSERETGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELVHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVTSGEEAKLKKRKPRVKKENKAPRLKDEHGLELSSPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKEKKKSKDKKEKVKGGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRSCLLKIGDRIAECLRAYSEQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDTLGGKKPFRPEASGSSRDSLISQSHASHNLHPQKPHLPASHGPQMHGHPRDTYSHPNKRHFSNADRGDWQRERKFNYGGGNNAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPTLHTALSDPRSPPAQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT" }, "uniprot_id": "A0A0G2KA92_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "chromodomain-helicase-DNA-binding protein 2 isoform X1" ], "uniprotkb": [ "Chromodomain helicase DNA-binding protein 2" ] }, "gene": { "refseq": [ "Chd2" ], "uniprotkb": [ "Chd2" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Chromodomain helicase DNA-binding protein 2." }, "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", "journal": "Nat. Commun.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92/publications", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", "date": "2012", "pmid": "22673903" } ], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92#A0A096MJY0-1", "isoform_ac": "A0A096MJY0-1", "locus": { "end_pos": 134760845, "start_pos": 134870255, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000076300", "id": "ENSRNOT00000076300", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000068303", "id": "ENSRNOP00000068303", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A096MJY0-1|A0A0G2KA92_RAT Computationally mapped isoform of Chromodomain helicase DNA-binding protein 2 OS=Rattus norvegicus OX=10116 GN=Chd2 PE=1 SV=1 CANONICAL=A0A0G2KA92-1", "length": 1827, "sequence": "MMRNKDKSQEEDSSLHSNASSHSASEEASASDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDDQEQGSSAESEAEQKKVKARRPIPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAVEANGDPSGDFDTEREEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEVNVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIRAPEDSERETGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELVHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVTSGEEAKLKKRKPRVKKENKAPRLKDEHGLELSSPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKEKKKSKDKKEKVKGGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRSCLLKIGDRIAECLRAYSEQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDTLGGKKPFRPEASGSSRDSLISQSHASHNLHPQKPHLPASHGPQMHGHPRDTYSHPNKRHFSNADRGDWQRERKFNYGGGNNAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPTLHTALSDPRSPPAQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92#A0A0G2KA92-1", "isoform_ac": "A0A0G2KA92-1", "locus": { "end_pos": 134760845, "start_pos": 134866805, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000090149", "id": "ENSRNOT00000090149", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000075309", "id": "ENSRNOP00000075309", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2KA92-1|A0A0G2KA92_RAT Isoform 1 of Chromodomain helicase DNA-binding protein 2 OS=Rattus norvegicus OX=10116 GN=Chd2 PE=1 SV=1 CANONICAL=A0A0G2KA92-1", "length": 1840, "sequence": "MAHKPREEHLSLSPCIFTWYQTFSQLTFEEEKLSHSASEEASASDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDDQEQGSSAESEAEQKKVKARRPIPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAVEANGDPSGDFDTEREEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEVNVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIRAPEDSERETGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELVHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVTSGEEAKLKKRKPRVKKENKAPRLKDEHGLELSSPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKEKKKSKDKKEKVKGGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRSCLLKIGDRIAECLRAYSEQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDTLGGKKPFRPEASGSSRDSLISQSHASHNLHPQKPHLPASHGPQMHGHPRDTYSHPNKRHFSNADRGDWQRERKFNYGGGNNAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPTLHTALSDPRSPPAQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92#D4AD08-1", "isoform_ac": "D4AD08-1", "locus": { "end_pos": 134760845, "start_pos": 134870255, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000055829", "id": "ENSRNOT00000055829", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000052684", "id": "ENSRNOP00000052684", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D4AD08-1|A0A0G2KA92_RAT Computationally mapped isoform of Chromodomain helicase DNA-binding protein 2 OS=Rattus norvegicus OX=10116 GN=Chd2 PE=1 SV=1 CANONICAL=A0A0G2KA92-1", "length": 1834, "sequence": "MMRNKDKSQEEDSSLHSNASSHSASEEASASDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDDQEQGSSAESEAEQKKVKARRPIPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGVDLNPFAATGASTTVYAVEANGDPSGDFDTEREEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEVNVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIRAPEDSERETGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELVHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVTSGEEAKLKKRKPRVKKENKAPRLKDEHGLELSSPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKEKKKSKDKKEKVKGGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRSCLLKIGDRIAECLRAYSEQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDTLGGKKPFRPEASGSSRDSLISQSHASHNLHPQKPHLPASHGPQMHGHPRDTYSHPNKRHFSNADRGDWQRERKFNYGGGNNAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPTLHTALSDPRSPPAQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT" } } ], "pathway": [], "function": [], "orthologs": [ { "uniprot_canonical_ac": "E9PZM4-1", "protein_name": "Chromodomain-helicase-DNA-binding protein 2; CHD-2; 3.6.4.12; ATP-dependent helicase CHD2.", "sequence": { "length": 1827, "sequence": "MMRNKDKSQEEDSSLHSNASSRSASEEVSGSDSGSQSESEQGSEPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNVKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDEQEQGTSAESEAEQKKGKARRPVPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGGDEQQDNSETIEKVLDSRLGKKGATGASTTVYAVEANGDPSDDFDTEREEGEVQYLIKWKGWSYIHSTWESEDSLQQQKVKGLKKLENFKKKEDEVKQWLGKVSPEDVEYFSCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGESLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKAPEDSERESGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKESTSEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVASGEEAKLKKRKPRVKKENKAPRLKDEHGLEPASPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKERKKSKDKKEKVKGGDGKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLSVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDSLGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHPRDNYSHPNKRHFSNADRGDWQRERKFNYGGGNSAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPSLHTALSDPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A0A0G2KA92/", "id": "A0A0G2KA92", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/37462", "id": "37462", "database": "MGI" } ], "organism": "Mus musculus", "tax_id": 10090 }, { "uniprot_canonical_ac": "O14647-1", "protein_name": "Chromodomain-helicase-DNA-binding protein 2; CHD-2; 3.6.4.12; ATP-dependent helicase CHD2.", "sequence": { "length": 1828, "sequence": "MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHPRDNYNHPNKRHFSNADRGDWQRERKFNYGGGNNNPPWGSDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYDQYSSDRDHRGHRDYYDRHHHDSKRRRSDEFRPQNYHQQDFRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVSDPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A0A0G2KA92/", "id": "A0A0G2KA92", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/37462", "id": "37462", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006229431.1", "ac": "XP_006229431.1", "name": "chromodomain-helicase-DNA-binding protein 2 isoform X1.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "name": "ATP binding", "id": "GO:0005524" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "name": "RNA polymerase II proximal promoter sequence-specific DNA binding", "id": "GO:0000978" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "name": "histone binding", "id": "GO:0042393" } ], "total": 3, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" } ], "total": 1, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060218", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "name": "hematopoietic stem cell differentiation", "id": "GO:0060218" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "name": "cellular response to DNA damage stimulus", "id": "GO:0006974" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "name": "muscle organ development", "id": "GO:0007517" } ], "total": 3, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 69, "annotation": "n_glycosylation_sequon", "start_pos": 67 }, { "end_pos": 128, "annotation": "n_glycosylation_sequon", "start_pos": 126 }, { "end_pos": 244, "annotation": "n_glycosylation_sequon", "start_pos": 242 }, { "end_pos": 463, "annotation": "n_glycosylation_sequon", "start_pos": 461 }, { "end_pos": 968, "annotation": "n_glycosylation_sequon", "start_pos": 966 }, { "end_pos": 1098, "annotation": "n_glycosylation_sequon", "start_pos": 1096 }, { "end_pos": 1210, "annotation": "n_glycosylation_sequon", "start_pos": 1208 }, { "end_pos": 1707, "annotation": "n_glycosylation_sequon", "start_pos": 1705 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006229431.1", "id": "XP_006229431.1", "database": "RefSeq" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000012716", "id": "ENSRNOG00000012716", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/NIWKDDD/", "id": "NIWKDDD", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "id": "IPR027417", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "id": "IPR000953", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "id": "IPR016197", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "id": "IPR000330", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "id": "IPR001650", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "id": "IPR014001", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR025260", "id": "IPR025260", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "id": "IPR023779", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "id": "IPR023780", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "id": "IPR038718", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR040793", "id": "IPR040793", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00176", "id": "PF00176", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00271", "id": "PF00271", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF13907", "id": "PF13907", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00385", "id": "PF00385", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF18375", "id": "PF18375", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/308738", "id": "308738", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1310056", "id": "1310056", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A0G2KA92", "disease": [], "mass": { "monoisotopic_mass": 212652.0, "chemical_mass": 212652.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "name": "Chd2.", "locus": { "end_pos": 134757934, "start_pos": 134871167, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000012716", "id": "ENSRNOG00000012716", "database": "Ensembl Gene" } ] } } ] }