{ "uniprot_canonical_ac": "A0A0G2KA11-1", "sequence": { "header": "tr|A0A0G2KA11-1|A0A0G2KA11_RAT Isoform 1 of Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 OS=Rattus norvegicus OX=10116 GN=Prex2 PE=1 SV=1 CANONICAL=A0A0G2KA11-1", "length": 1598, "sequence": "MSDESARDADKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAAAKLDKNVTEETVKMLFSNIEEILAVHKEFLKVVEECLHPEPNAQQEVGTCFLNFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLLLKELLKRTPRKHSDYTAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQAHIEGWEGSNITDTCTEMLMCGVLMKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYVFRGRINTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKSPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMCKQGNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRSEMQDVISKGVRLYCRLHSLFTPVVRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFAVGLCDNGFMHHVLEKSEFKDEPLLFRFFADEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFLRPFPEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYKRPMKQDSIQWVYDSLESAQEDIQKSHSKPPGDEAGDVFDCKVEDVMDKFNTLAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGTKCNVVEKMVEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIATDLQSKFTSMCSERVEHVCHRISSYGRFSRVLKNRAWPTFKQAKAKMSPLHSSDFCPTNCHVNVMEVSYPKASASLGSAFGVQLDSRKHNSHDKENRSADPGKLSPMVYIQHTITTMAAPSGLSLGHKDGHGLRYLLKEEDLETQDIYHKLLGKLQTALKEVEMCVCQIDDLLSSITYSPKLERKTTEYVIPTDSDNEKGERNSKRVCFNVAGDEQEDSGHDTVSNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDSGDELPTSIRISHDKQDKIHTCLEQLFIQLDSITNLLKGRAVVRAFEQTKYLTPGRGLQEFQQEMEAKLSCPRRLRLHLKQDPWNLPSGVRALAQSFRKYVEEVKCRILLALLEYSDSETQLRRDMVFCQSLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAGVLFHFQSLLSPNLKDEQAMLEDTLVALFDLEKVSFFFKPSEEEPLVANVPLTYQVEGSRQALKVVFYMDSYHFEQLPQRLKNGGGFKIHPVLFSQALESMEGYCYRDNISVEEFQAQINTASLEKVKQYNQKLRAFYLDKSNSPPNATSKAAYIEKLMRPLNALDELYRLVTSFIRSKRIAACVNTPCSASGVGLLSVSSELCDRLGACHIIMCSSGVHRCTLSVTLEQAITLARSHGLPPRYIMQATDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPVGDE" }, "uniprot_id": "A0A0G2KA11_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X1" ], "uniprotkb": [ "Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2" ] }, "gene": { "refseq": [ "Prex2", "Depdc2" ], "uniprotkb": [ "Prex2", "Depdc2" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11", "id": "A0A0G2KA11", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2." }, "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", "journal": "Nat. Commun.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11/publications", "id": "A0A0G2KA11", "database": "UniProtKB" } ], "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", "date": "2012", "pmid": "22673903" } ], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11#A0A0G2KA11-1", "isoform_ac": "A0A0G2KA11-1", "locus": { "end_pos": 7628439, "start_pos": 7941294, "chromosome": "5", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000079917", "id": "ENSRNOT00000079917", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000075213", "id": "ENSRNOP00000075213", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2KA11-1|A0A0G2KA11_RAT Isoform 1 of Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 OS=Rattus norvegicus OX=10116 GN=Prex2 PE=1 SV=1 CANONICAL=A0A0G2KA11-1", "length": 1598, "sequence": "MSDESARDADKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAAAKLDKNVTEETVKMLFSNIEEILAVHKEFLKVVEECLHPEPNAQQEVGTCFLNFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLLLKELLKRTPRKHSDYTAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQAHIEGWEGSNITDTCTEMLMCGVLMKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYVFRGRINTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKSPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMCKQGNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRSEMQDVISKGVRLYCRLHSLFTPVVRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFAVGLCDNGFMHHVLEKSEFKDEPLLFRFFADEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFLRPFPEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYKRPMKQDSIQWVYDSLESAQEDIQKSHSKPPGDEAGDVFDCKVEDVMDKFNTLAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGTKCNVVEKMVEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIATDLQSKFTSMCSERVEHVCHRISSYGRFSRVLKNRAWPTFKQAKAKMSPLHSSDFCPTNCHVNVMEVSYPKASASLGSAFGVQLDSRKHNSHDKENRSADPGKLSPMVYIQHTITTMAAPSGLSLGHKDGHGLRYLLKEEDLETQDIYHKLLGKLQTALKEVEMCVCQIDDLLSSITYSPKLERKTTEYVIPTDSDNEKGERNSKRVCFNVAGDEQEDSGHDTVSNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDSGDELPTSIRISHDKQDKIHTCLEQLFIQLDSITNLLKGRAVVRAFEQTKYLTPGRGLQEFQQEMEAKLSCPRRLRLHLKQDPWNLPSGVRALAQSFRKYVEEVKCRILLALLEYSDSETQLRRDMVFCQSLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAGVLFHFQSLLSPNLKDEQAMLEDTLVALFDLEKVSFFFKPSEEEPLVANVPLTYQVEGSRQALKVVFYMDSYHFEQLPQRLKNGGGFKIHPVLFSQALESMEGYCYRDNISVEEFQAQINTASLEKVKQYNQKLRAFYLDKSNSPPNATSKAAYIEKLMRPLNALDELYRLVTSFIRSKRIAACVNTPCSASGVGLLSVSSELCDRLGACHIIMCSSGVHRCTLSVTLEQAITLARSHGLPPRYIMQATDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPVGDE" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11#D3ZW14-1", "isoform_ac": "D3ZW14-1", "locus": { "end_pos": 7628439, "start_pos": 7845262, "chromosome": "5", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000064774", "id": "ENSRNOT00000064774", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000063421", "id": "ENSRNOP00000063421", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D3ZW14-1|A0A0G2KA11_RAT Computationally mapped isoform of Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 OS=Rattus norvegicus OX=10116 GN=Prex2 PE=1 SV=1 CANONICAL=A0A0G2KA11-1", "length": 1216, "sequence": "MCGVLMKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYVFRGRINTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKSPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMCKQGNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRSEMQDVISKGVRLYCRLHSLFTPVVRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFAVGLCDNGFMHHVLEKSEFKDEPLLFRFFADEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFLRPFPEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYKRPMKQDSIQWVYDSLESAQEDIQKSHSKPPGDEAGDVFDCKVEDVMDKFNTLAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGTKCNVVEKMVEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIATDLQSKFTSMCSERVEHVCHRISSYGRFSRVLKNRAWPTFKQAKAKMSPLHSSDFCPTNCHVNVMEVSYPKASASLGSAFGVQLDSRKHNSHDKENRSADPGKLSPMVYIQHTITTMAAPSGLSLGHKDGHGLRYLLKEEDLETQDIYHKLLGKLQTALKEVEMCVCQIDDLLSSITYSPKLERKTTEYVIPTDSDNEKGERNSKRVCFNVAGDEQEDSGHDTVSNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDSGDELPTSIRISHDKQDKIHTCLEQLFIQLDSITNLLKGRAVVRAFEQTKYLTPGRGLQDSETQLRRDMVFCQSLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAGVLFHFQSLLSPNLKDEQAMLEDTLVALFDLEKVSFFFKPSEEEPLVANVPLTYQVEGSRQALKVVFYMDSYHFEQLPQRLKNGGGFKIHPVLFSQALESMEGYCYRDNISVEEFQAQINTASLEKVKQYNQKLRCTLSVTLEQAITLARSHGLPPRYIMQATDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPVGDE" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8948751", "resource": "Reactome", "id": "R-RNO-8948751", "name": "Regulation of PTEN stability and activity" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q70Z35-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; P-Rex2; PtdIns(3,4,5)-dependent Rac exchanger 2; DEP domain-containing protein 2.", "sequence": { "length": 1606, "sequence": "MSEDSRGDSRAESAKDLEKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIEDILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPRKHSDYAAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQSHIEGWEGSNITDTCTEMLMCGVLLKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYLFRGRINTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKTPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMCRQGNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRNEMQDVISKGVRLYCRLHSLFTPVIRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLCDNGFMHHVLEKSEFKDEPLLFRFFSDEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFMRPFNEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYRRPTKQDSIQWVYNSIESAQEDLQKSHSKPPGDEAGDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGIKCNVVEKMIEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQSKFSALCSERIEHLCQRISSYKKFSRVLKNRAWPTFKQAKSKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSSEQGKLSPMVYIQHTITTMAAPSGLSLGQQDGHGLRYLLKEEDLETQDIYQKLLGKLQTALKEVEMCVCQIDDLLSSITYSPKLERKTSEGIIPTDSDNEKGERNSKRVCFNVAGDEQEDSGHDTISNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDSGDELPLSVRISHDKQDKIHSCLEHLFSQVDSITNLLKGQAVVRAFDQTKYLTPGRGLQEFQQEMEPKLSCPKRLRLHIKQDPWNLPSSVRTLAQNIRKFVEEVKCRLLLALLEYSDSETQLRRDMVFCQTLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAGVLFHFQSLLSPNLTDEQAMLEDTLVALFDLEKVSFYFKPSEEEPLVANVPLTYQAEGSRQALKVYFYIDSYHFEQLPQRLKNGGGFKIHPVLFAQALESMEGYYYRDNVSVEEFQAQINAASLEKVKQYNQKLRAFYLDKSNSPPNSTSKAAYVDKLMRPLNALDELYRLVASFIRSKRTAACANTACSASGVGLLSVSSELCNRLGACHIIMCSSGVHRCTLSVTLEQAIILARSHGLPPRYIMQATDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPAGEE" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A0A0G2KA11/", "id": "A0A0G2KA11", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/23523", "id": "23523", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "Q3LAC4-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; P-Rex2; PtdIns(3,4,5)-dependent Rac exchanger 2; DEP domain-containing protein 2.", "sequence": { "length": 1598, "sequence": "MSDESAREVDKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAAAKVDKNVTEETVKMLFSNIEEILIVHKEFLKVVEECLYPEPSAQQEVGACFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLLLKELLKRTPRRHSDYTAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQAHIEGWEGSNITDTCTEMLMCGVLMKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGYRYVFRGRINTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKSPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMCKQGNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRSEMQDVISKGVRLYCRLHSLFTPVVRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFAVGLCDNGFMHHVLEKSEFKDEPLLFRFFADEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFLRPFPEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYKRPMKQDSIQWVYDSLESAQEDIQKSHSKPPGDGAGDAFECKVEDVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGTKCNVVEKMVEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIATDLQSKFTSMCSERIEHVCHRISSYGRFSRVLKNRAWPTFKQAKPKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSVEPGKLSPMVYIQHTITTMAAPSGLSLGHKDGHGLQYLLKEEDLETQDIYHKLLGKLQTALKEVEMSVCQIDDLLSSITYSPKLERKTTECVTPMDSDNEKGERNSKRVCFNVAGDEQEDSGHDTVSNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDSGDELPISVRISHDKQDKIHTCLEQLFSQIDSIINLLKGQAVIRAFEQTKYLTPGRGLQEFQQEMEAKLSCPRRLRLHLKQDPWNLPSSIQALAQSIRKHAEEVKCRILLALLEYSDSETQLRRDMVFCQSLVATVCAFSEQLMAALNQMFDNSKENEMETCEASRRWLDQIANAGVLFHFQSLLSPNLKDEQAMLEDTLVALFDLEKVSFFFKPSEEDPLVANVPLTYQVEGSRQALKVYFYMDSYHFEQLPQRLKNGGGFKIHPVLFSQALESMEGYCYRDNISVEEFQAQINTASLEKVKQYNQKLRAFYLDKSNSPPNTTSKAAYIDKLMKPLNALDELYRLITSFIRSKRIAACVNTPCSASGVGLLSVSSELCDRLGACHIIMCSSGVHRCTLSVTLEQTITLARSHGLPPRYIMQAMDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPVGEE" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A0A0G2KA11/", "id": "A0A0G2KA11", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/23523", "id": "23523", "database": "MGI" } ], "organism": "Mus musculus", "tax_id": 10090 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006237815.1", "ac": "XP_006237815.1", "name": "phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X1.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030676", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11", "id": "A0A0G2KA11", "database": "UniProtKB" } ], "name": "Rac guanyl-nucleotide exchange factor activity", "id": "GO:0030676" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11", "id": "A0A0G2KA11", "database": "UniProtKB" } ], "name": "GTPase activator activity", "id": "GO:0005096" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11", "id": "A0A0G2KA11", "database": "UniProtKB" } ], "name": "plasma membrane", "id": "GO:0005886" } ], "total": 1, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11", "id": "A0A0G2KA11", "database": "UniProtKB" } ], "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008344", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11", "id": "A0A0G2KA11", "database": "UniProtKB" } ], "name": "adult locomotory behavior", "id": "GO:0008344" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014065", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11", "id": "A0A0G2KA11", "database": "UniProtKB" } ], "name": "phosphatidylinositol 3-kinase signaling", "id": "GO:0014065" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11", "id": "A0A0G2KA11", "database": "UniProtKB" } ], "name": "regulation of Rho protein signal transduction", "id": "GO:0035023" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11", "id": "A0A0G2KA11", "database": "UniProtKB" } ], "name": "dendrite morphogenesis", "id": "GO:0048813" } ], "total": 5, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 58, "annotation": "n_glycosylation_sequon", "start_pos": 56 }, { "end_pos": 232, "annotation": "n_glycosylation_sequon", "start_pos": 230 }, { "end_pos": 720, "annotation": "n_glycosylation_sequon", "start_pos": 718 }, { "end_pos": 860, "annotation": "n_glycosylation_sequon", "start_pos": 858 }, { "end_pos": 968, "annotation": "n_glycosylation_sequon", "start_pos": 966 }, { "end_pos": 1417, "annotation": "n_glycosylation_sequon", "start_pos": 1415 }, { "end_pos": 1455, "annotation": "n_glycosylation_sequon", "start_pos": 1453 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006237815.1", "id": "XP_006237815.1", "database": "RefSeq" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8948751", "id": "R-RNO-8948751", "database": "Reactome" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000005391", "id": "ENSRNOG00000005391", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/QNCNSLN/", "id": "QNCNSLN", "database": "OMA" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "id": "cd00160", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04439", "id": "cd04439", "database": "CDD" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "id": "IPR001849", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "id": "IPR011993", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "id": "IPR000219", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001331", "id": "IPR001331", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "id": "IPR035899", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "id": "IPR036388", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "id": "IPR036390", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "id": "IPR001478", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "id": "IPR036034", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "id": "IPR000591", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR037367", "id": "IPR037367", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00169", "id": "PF00169", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00621", "id": "PF00621", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00610", "id": "PF00610", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/312912", "id": "312912", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1307865", "id": "1307865", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A0G2KA11", "disease": [], "mass": { "monoisotopic_mass": 181736.0, "chemical_mass": 181736.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA11", "name": "Prex2; Depdc2.", "locus": { "end_pos": 7627771, "start_pos": 7941822, "chromosome": "5", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000005391", "id": "ENSRNOG00000005391", "database": "Ensembl Gene" } ] } } ] }