{
    "uniprot_canonical_ac": "A0A0G2K7S2-1", 
    "sequence": {
        "header": "tr|A0A0G2K7S2-1|A0A0G2K7S2_RAT Isoform 1 of Integrator complex subunit 6  OS=Rattus norvegicus OX=10116 GN=Ints6 PE=1 SV=1 CANONICAL=A0A0G2K7S2-1", 
        "length": 883, 
        "sequence": "MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTVSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPAEDGQPDISRPFGSQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYNELGHPFGYLKASTALTCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAHRKGFQVLQGISEDVPHRLLDLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRKFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHKRPGEPSMQGIPKRRRCASPLLRGRRQSPAVNSHIGGKGPPAPMTQAQPGLIKPLPLHKEATNDSVVDDVVENHVADQLSSDMTTNAMDTEFLTSPANLLEPSTNHTEALGHEHLGNNDLTVGGFLENHEESRSKEQSAEENIPASSLNKGKKLMHCRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRRANQINHINSN"
    }, 
    "uniprot_id": "A0A0G2K7S2_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "integrator complex subunit 6", 
                "DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26"
            ], 
            "uniprotkb": [
                "Integrator complex subunit 6"
            ]
        }, 
        "gene": {
            "refseq": [
                "Ints6", 
                "Ddx26", 
                "LRRGT00024"
            ], 
            "uniprotkb": [
                "Ints6", 
                "Ddx26", 
                "LRRGT00024"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K7S2", 
                    "id": "A0A0G2K7S2", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Integrator complex subunit 6."
    }, 
    "publication": [
        {
            "title": "Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/23904267", 
            "journal": "Molecular biology of the cell", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258417.1", 
                    "id": "NP_001258417.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Jodoin JN, Sitaram P, Albrecht TR, May SB, Shboul M, Lee E, Reversade B, Wagner EJ, Lee LA", 
            "date": "2013", 
            "pmid": "23904267"
        }, 
        {
            "title": "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/16239144", 
            "journal": "Cell", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258417.1", 
                    "id": "NP_001258417.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R", 
            "date": "2005", 
            "pmid": "16239144"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K7S2#Q6TXH5-1", 
            "isoform_ac": "Q6TXH5-1", 
            "locus": {
                "end_pos": 45901199, 
                "start_pos": 45947030, 
                "chromosome": "15", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000035888", 
                        "id": "ENSRNOT00000035888", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000034419", 
                        "id": "ENSRNOP00000034419", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|Q6TXH5-1|A0A0G2K7S2_RAT Computationally mapped isoform of Integrator complex subunit 6  OS=Rattus norvegicus OX=10116 GN=Ints6 PE=1 SV=1 CANONICAL=A0A0G2K7S2-1", 
                "length": 344, 
                "sequence": "MYLLAAPKAQTAEGDAKRPCVIKAELGTTAGITGGGEQLDSQDSILLKTPAKTSFSPILDGYPSEKAFTVWQHSSGTRHSQALYSIRVISSVEALEILGLNLGPLFKKPVFSSRGPRSPPRISAVAAAAGASTSAISSPPRAPVSPASTMPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELKEQPSGFQEVPKCTDCLMMTGASGRVMIPGYRIDLILDVTSSSHFVGKSLV"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K7S2#A0A0G2K7S2-1", 
            "isoform_ac": "A0A0G2K7S2-1", 
            "locus": {
                "end_pos": 45859778, 
                "start_pos": 45927579, 
                "chromosome": "15", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000086271", 
                        "id": "ENSRNOT00000086271", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000074321", 
                        "id": "ENSRNOP00000074321", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2K7S2-1|A0A0G2K7S2_RAT Isoform 1 of Integrator complex subunit 6  OS=Rattus norvegicus OX=10116 GN=Ints6 PE=1 SV=1 CANONICAL=A0A0G2K7S2-1", 
                "length": 883, 
                "sequence": "MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTVSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPAEDGQPDISRPFGSQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYNELGHPFGYLKASTALTCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAHRKGFQVLQGISEDVPHRLLDLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRKFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHKRPGEPSMQGIPKRRRCASPLLRGRRQSPAVNSHIGGKGPPAPMTQAQPGLIKPLPLHKEATNDSVVDDVVENHVADQLSSDMTTNAMDTEFLTSPANLLEPSTNHTEALGHEHLGNNDLTVGGFLENHEESRSKEQSAEENIPASSLNKGKKLMHCRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRRANQINHINSN"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:361057", 
            "resource": "KEGG Pathway", 
            "id": "rno:361057", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6807505", 
            "resource": "Reactome", 
            "id": "R-RNO-6807505", 
            "name": "RNA polymerase II transcribes snRNA genes"
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q6PCM2-1", 
            "protein_name": "Integrator complex subunit 6; Int6; DBI-1; Protein DDX26.", 
            "sequence": {
                "length": 883, 
                "sequence": "MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTMSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPPPAEEGQPDISRPFGSQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYNELGHPFGYLKASTALTCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAHRKGFQVLQGISEDVPHRLLDLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRKFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHKRPGEPSMQGIPKRRRCASPLLRGRRQSPAVNSHIGGKGPPAPMTQAQPGLIKPLPLHKEATNDSIVDDVVENHVADQLSSDMTPNAMDTEFLTSPPNLLEPSTNHTEALGHEHLGNNDLTVGGFLENHEEPRNKEQSAEENIPASSLNKGKKLMHCRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRRANQINHINSN"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/8121", 
                    "id": "8121", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2K7S2/", 
                    "id": "A0A0G2K7S2", 
                    "database": "OMA"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q9UL03-1", 
            "protein_name": "Integrator complex subunit 6; Int6; Protein deleted in cancer 1; DICE1; DBI-1; Protein DDX26.", 
            "sequence": {
                "length": 887, 
                "sequence": "MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTMSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPVEDGQPDISRPFGSQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYSELGHPFGYLKASTALNCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAYRKDFQQLLQGISEDVPHRLLDLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRRFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHKRPGEPNMQGIPKRRRCMSPLLRGRQQNPVVNNHIGGKGPPAPTTQAQPDLIKPLPLHKISETTNDSIIHDVVENHVADQLSSDITPNAMDTEFSASSPASLLERPTNHMEALGHDHLGTNDLTVGGFLENHEEPRDKEQCAEENIPASSLNKGKKLMHCRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRRANQINHINSN"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/8121", 
                    "id": "8121", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2K7S2/", 
                    "id": "A0A0G2K7S2", 
                    "database": "OMA"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258417.1", 
        "ac": "NP_001258417.1", 
        "name": "integrator complex subunit 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K7S2", 
                                "id": "A0A0G2K7S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integrator complex", 
                        "id": "GO:0032039"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K7S2", 
                                "id": "A0A0G2K7S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleoplasm", 
                        "id": "GO:0005654"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K7S2", 
                                "id": "A0A0G2K7S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "actin cytoskeleton", 
                        "id": "GO:0015629"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K7S2", 
                                "id": "A0A0G2K7S2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "snRNA 3'-end processing", 
                        "id": "GO:0034472"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 706, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 704
        }, 
        {
            "end_pos": 748, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 746
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258417.1", 
            "id": "NP_001258417.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6807505", 
            "id": "R-RNO-6807505", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:361057", 
            "id": "rno:361057", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000009873", 
            "id": "ENSRNOG00000009873", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/ADNMEYG/", 
            "id": "ADNMEYG", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029307", 
            "id": "IPR029307", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", 
            "id": "IPR002035", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", 
            "id": "IPR036465", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF15300", 
            "id": "PF15300", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF13519", 
            "id": "PF13519", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/361057", 
            "id": "361057", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1309480", 
            "id": "1309480", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2K7S2", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 99532.0, 
        "chemical_mass": 99532.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K7S2", 
            "name": "Ints6; Ddx26; LRRGT00024.", 
            "locus": {
                "end_pos": 45858608, 
                "start_pos": 45947030, 
                "chromosome": "15", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000009873", 
                        "id": "ENSRNOG00000009873", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}