{ "uniprot_canonical_ac": "A0A0G2K7R4-1", "sequence": { "header": "tr|A0A0G2K7R4-1|A0A0G2K7R4_RAT Isoform 1 of Olfactory receptor OS=Rattus norvegicus OX=10116 GN=Olr456 PE=3 SV=1 CANONICAL=A0A0G2K7R4-1", "length": 304, "sequence": "MDHNNTVSEFIMLGFTTDPVMQKVLFAVFLIVYTLTLIGNCSLIMLICNDSRLHTPMYFFIGNLSFLDLGLSSVYTPKILATCISEDKSISFAGCVTQFFFSAALDYTECYLLAAMAYDRYVAISKPLLYSQAMSLKLCVFFVAASYLGGFINSVIITKDTFALTFCSDNVIDDFFCDIPPLVKLACGKKDSFQSVLFFLLTSNVIIPIVFILATYLFIIATILRIRSTQGRLKAFSTCSSHLISVTLYYGSILYIYARPRSSYSLDRDKIVSTFYTVVFPMLNPLIYSLRNKDVKEALNKLLK" }, "uniprot_id": "A0A0G2K7R4_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "olfactory receptor Olr456", "olfactory receptor gene Olr456" ], "uniprotkb": [ "Olfactory receptor" ] }, "gene": { "refseq": [ "Olr456" ], "uniprotkb": [ "Olr456", "rCG_26666" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4", "id": "A0A0G2K7R4", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Olfactory receptor." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4#A0A0G2K7R4-1", "isoform_ac": "A0A0G2K7R4-1", "locus": { "end_pos": 73138229, "start_pos": 73139140, "chromosome": "3", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000092148", "id": "ENSRNOT00000092148", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000074312", "id": "ENSRNOP00000074312", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K7R4-1|A0A0G2K7R4_RAT Isoform 1 of Olfactory receptor OS=Rattus norvegicus OX=10116 GN=Olr456 PE=3 SV=1 CANONICAL=A0A0G2K7R4-1", "length": 304, "sequence": "MDHNNTVSEFIMLGFTTDPVMQKVLFAVFLIVYTLTLIGNCSLIMLICNDSRLHTPMYFFIGNLSFLDLGLSSVYTPKILATCISEDKSISFAGCVTQFFFSAALDYTECYLLAAMAYDRYVAISKPLLYSQAMSLKLCVFFVAASYLGGFINSVIITKDTFALTFCSDNVIDDFFCDIPPLVKLACGKKDSFQSVLFFLLTSNVIIPIVFILATYLFIIATILRIRSTQGRLKAFSTCSSHLISVTLYYGSILYIYARPRSSYSLDRDKIVSTFYTVVFPMLNPLIYSLRNKDVKEALNKLLK" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/www_bget?rno:404892", "resource": "KEGG Pathway", "id": "rno:404892", "name": "" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q7TR96-1", "protein_name": "Olfactory receptor 1013; Olfactory receptor 213-2.", "sequence": { "length": 305, "sequence": "MDQNNNTVSEFIMLGFTTDPVIQKVLFAVFLVVYTLTLMGNSSLIMLICNDSRLHTPMYFFIGNLSFLDLGLSSVYTPKILETCISEDKSISFAGCVAQFFFSAALDYTECYLLAAMAYDRYVAISKPLLYSQAMSLKLCVCFVVASYVGGFINSVIITKDTFALTFCNDNVIDDFFCDIPPLVKLACGKKKSFQSVLFFLLTSNVIIPIVFILATYLFIIATILRIRSTQGRLKAFSTCSSHLISVTLYYGSILYIYARPRSSYSLDRDKIVSTFYTVVFPMLNPLIYSLRNKDVKEALNKLLK" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/74096", "id": "74096", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A0A0G2K7R4/", "id": "A0A0G2K7R4", "database": "OMA" } ], "organism": "Mus musculus", "tax_id": 10090 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000687.1", "ac": "NP_001000687.1", "name": "olfactory receptor Olr456; olfactory receptor gene Olr456.", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]." }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4", "id": "A0A0G2K7R4", "database": "UniProtKB" } ], "name": "olfactory receptor activity", "id": "GO:0004984" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4", "id": "A0A0G2K7R4", "database": "UniProtKB" } ], "name": "odorant binding", "id": "GO:0005549" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4", "id": "A0A0G2K7R4", "database": "UniProtKB" } ], "name": "G protein-coupled receptor activity", "id": "GO:0004930" } ], "total": 3, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4", "id": "A0A0G2K7R4", "database": "UniProtKB" } ], "name": "plasma membrane", "id": "GO:0005886" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4", "id": "A0A0G2K7R4", "database": "UniProtKB" } ], "name": "integral component of membrane", "id": "GO:0016021" } ], "total": 2, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4", "id": "A0A0G2K7R4", "database": "UniProtKB" } ], "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4", "id": "A0A0G2K7R4", "database": "UniProtKB" } ], "name": "sensory perception of smell", "id": "GO:0007608" } ], "total": 2, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 6, "annotation": "n_glycosylation_sequon", "start_pos": 4 }, { "end_pos": 42, "annotation": "n_glycosylation_sequon", "start_pos": 40 }, { "end_pos": 51, "annotation": "n_glycosylation_sequon", "start_pos": 49 }, { "end_pos": 65, "annotation": "n_glycosylation_sequon", "start_pos": 63 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000687.1", "id": "NP_001000687.1", "database": "RefSeq" }, { "url": "https://www.genome.jp/dbget-bin/www_bget?rno:404892", "id": "rno:404892", "database": "KEGG Pathway" }, { "url": "https://omabrowser.org/oma/group/FYSQAMS/", "id": "FYSQAMS", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "id": "IPR000276", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "id": "IPR017452", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "id": "IPR000725", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF13853", "id": "PF13853", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/404892", "id": "404892", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1333552", "id": "1333552", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A0G2K7R4", "disease": [], "mass": { "monoisotopic_mass": 34210.0, "chemical_mass": 34210.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4", "name": "Olr456; rCG_26666.", "locus": { "end_pos": 73139143, "start_pos": 73138229, "chromosome": "3", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000061609", "id": "ENSRNOG00000061609", "database": "Ensembl Gene" } ] } } ] }