{
    "uniprot_canonical_ac": "A0A0G2K7L2-1", 
    "sequence": {
        "header": "tr|A0A0G2K7L2-1|A0A0G2K7L2_RAT Isoform 1 of Immunoglobulin superfamily, member 3  OS=Rattus norvegicus OX=10116 GN=Igsf3 PE=4 SV=1 CANONICAL=A0A0G2K7L2-1", 
        "length": 1190, 
        "sequence": "MKCFFPVLSCLAVLGAVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPAEQNFQWSIYLPSAPEREVQIVSTVDSSFPYAIYTQRVRGGKIYVERIQGNSALLHITDLQARDAGEYECHTPNTDERYFGSYSAKMNLVVIPDSLQTTAVPQTLHKVEQDPLELSCEVATETLQHTHLSVSWLRQKGGENPVEVISLSRDFILHSSSEYAQRQSLGEVRLDKLGRSTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETDKRLHTVGEPVEFRCILEAQNIPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREAKGQLKVAKEGDGVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIVVLPLKSSMSVEVASNASVVLEGEDLHFSCTVRTVGRLQARFSVIWQLVDRQNRRSNVMWLDRDGTVQPGSSYWERSSYGGIQMEQVQPNSFSLGIFSSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTLVSITALETGFAVTAISRTPGVTYSDSFDLQCIIKPHYPARVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDKSSTFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRRNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENRPIQLNCSVKSQTSPNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRGRLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLKLSQAQGSLSILETRQIQLECVVLNRTSMASQLVVEWFVWKPNHPEREVVAHLSRDATFHYGEQAAKNNLKGRLHVESPSSGVYRLFIQNVAVQDSGTYSCRVEEWLLSPSGVWYKRAEDTAGQTAVTVMRPDAALQVDTVVPNATVTEKATFQLDCSILSRSSQDSRFAVAWYSLRTKGGGKRGSLGIDEQEEEEVSEEEASEDPTERTVLLSVGPDAVFGPEGSPWEGRLRFQRLSPLLYRLTVLEASPQDTGNYSCHVEEWLPSPQKGWYRLTEEESAPIGIRVLDTSSTLQSLICSNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSEGKNGVPLLWIKEPHLNYSPTCLEPPVLSIHPGAID"
    }, 
    "uniprot_id": "A0A0G2K7L2_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "immunoglobulin superfamily member 3 isoform X3"
            ], 
            "uniprotkb": [
                "Immunoglobulin superfamily, member 3"
            ]
        }, 
        "gene": {
            "refseq": [
                "Igsf3"
            ], 
            "uniprotkb": [
                "Igsf3"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K7L2", 
                    "id": "A0A0G2K7L2", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Immunoglobulin superfamily, member 3."
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K7L2#A0A0G2K7L2-1", 
            "isoform_ac": "A0A0G2K7L2-1", 
            "locus": {
                "end_pos": 203768729, 
                "start_pos": 203852200, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000080176", 
                        "id": "ENSRNOT00000080176", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000074253", 
                        "id": "ENSRNOP00000074253", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2K7L2-1|A0A0G2K7L2_RAT Isoform 1 of Immunoglobulin superfamily, member 3  OS=Rattus norvegicus OX=10116 GN=Igsf3 PE=4 SV=1 CANONICAL=A0A0G2K7L2-1", 
                "length": 1190, 
                "sequence": "MKCFFPVLSCLAVLGAVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPAEQNFQWSIYLPSAPEREVQIVSTVDSSFPYAIYTQRVRGGKIYVERIQGNSALLHITDLQARDAGEYECHTPNTDERYFGSYSAKMNLVVIPDSLQTTAVPQTLHKVEQDPLELSCEVATETLQHTHLSVSWLRQKGGENPVEVISLSRDFILHSSSEYAQRQSLGEVRLDKLGRSTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETDKRLHTVGEPVEFRCILEAQNIPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREAKGQLKVAKEGDGVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIVVLPLKSSMSVEVASNASVVLEGEDLHFSCTVRTVGRLQARFSVIWQLVDRQNRRSNVMWLDRDGTVQPGSSYWERSSYGGIQMEQVQPNSFSLGIFSSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTLVSITALETGFAVTAISRTPGVTYSDSFDLQCIIKPHYPARVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDKSSTFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRRNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENRPIQLNCSVKSQTSPNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRGRLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLKLSQAQGSLSILETRQIQLECVVLNRTSMASQLVVEWFVWKPNHPEREVVAHLSRDATFHYGEQAAKNNLKGRLHVESPSSGVYRLFIQNVAVQDSGTYSCRVEEWLLSPSGVWYKRAEDTAGQTAVTVMRPDAALQVDTVVPNATVTEKATFQLDCSILSRSSQDSRFAVAWYSLRTKGGGKRGSLGIDEQEEEEVSEEEASEDPTERTVLLSVGPDAVFGPEGSPWEGRLRFQRLSPLLYRLTVLEASPQDTGNYSCHVEEWLPSPQKGWYRLTEEESAPIGIRVLDTSSTLQSLICSNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSEGKNGVPLLWIKEPHLNYSPTCLEPPVLSIHPGAID"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K7L2#F1LZ40-1", 
            "isoform_ac": "F1LZ40-1", 
            "locus": {
                "end_pos": 203768729, 
                "start_pos": 203852200, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000018895", 
                        "id": "ENSRNOT00000018895", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000018894", 
                        "id": "ENSRNOP00000018894", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|F1LZ40-1|A0A0G2K7L2_RAT Computationally mapped isoform of Immunoglobulin superfamily, member 3  OS=Rattus norvegicus OX=10116 GN=Igsf3 PE=4 SV=2 CANONICAL=A0A0G2K7L2-1", 
                "length": 1064, 
                "sequence": "MKCFFPVLSCLAVLVIPDSLQTTAVPQTLHKVEQDPLELSCEVATETLQHTHLSVSWLRQKGGENPVEVISLSRDFILHSSSEYAQRQSLGEVRLDKLGRSTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETDKRLHTVGEPVEFRCILEAQNIPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREAKGQLKVAKEGDGVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIVVLPLKSSMSVEVASNASVVLEGEDLHFSCTVRTVGRLQARFSVIWQLVDRQNRRSNVMWLDRDGTVQPGSSYWERSSYGGIQMEQVQPNSFSLGIFSSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTLVSITALETGFAVTAISRTPGVTYSDSFDLQCIIKPHYPARVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDKSSTFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRRNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENRPIQLNCSVKSQTSPNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRGRLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLKLSQAQGSLSILETRQIQLECVVLNRTSMASQLVVEWFVWKPNHPEREVVAHLSRDATFHYGEQAAKNNLKGRLHVESPSSGVYRLFIQNVAVQDSGTYSCRVEEWLLSPSGVWYKRAEDTAGQTAVTVMRPDAALQVDTVVPNATVTEKATFQLDCSILSRSSQDSRFAVAWYSLRTKGGGKRGSLGIDEQEEEEVSEEEASEDPTERTVLLSVGPDAVFGPEGSPWEGRLRFQRLSPLLYRLTVLEASPQDTGNYSCHVEEWLPSPQKGWYRLTEEESAPIGIRVLDTSSTLQSLICSNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSEGKNGVPLLWIKEPHLNYSPTCLEPPVLSIHPGAID"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q6ZQA6-1", 
            "protein_name": "Immunoglobulin superfamily member 3; IgSF3.", 
            "sequence": {
                "length": 1194, 
                "sequence": "MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTESSHITIWCNVSGYQGPSEQNFQWSIYLPSAPEREVQIVSTVDSSFPYAIYTQRVRGGKIYVERIQGNSALLHITDLQARDAGEYECHTPNTDERYFGSYSAKMNLVVIPDSLQTTAVPQTLHKVEQDPLELSCEVATETVQHTHLSVSWLRQKGGENPVEVISLSRDFILHSSSEYAQRQSLGEVRLDKLGRSTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETDKRLHTVGEPVEFRCILEAQNIPDRYFAVSWAFNSSLIATMGPNAVPVLNSDFAHREAKGQLKVAKESDGVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIVVLPLKSSISVEVASNASVVLEGEDLHFSCTVRTVGRLQARFSVIWQLVDRQNRRSNVMWLDRDGTLQPGSAYWERSSYGGIQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTLVSITALETGFAVTAISRTPGVTYSDSFDLQCIIKPHYPARVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDKSSTFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRRNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENRAIQLNCSVKSQTSPNSHFAVLWYVHKPSDADGKLILKTTHSSAFEYGTYAEEEGLRGRLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLKLSQVQGSLSVLETRQIQLECVVLNRTSVASQLLVEWFVWKPNHPEREVVAHLSRDATFHYGEQAAKNNLKGRLHAESPSSGVYRLFIQNVAVQDSGTYSCRVEEWLPSPSGVWYKRAEDTAGQTAVTVMRPDAALQVDTVVPNATVTEKAAFQLDCSILSRSSQDSRFAVAWYSLRTKGGGKRGSLGIDEQEEEEEEEDISQEEDSEDPTERTVLLSVGPDAVFGPEGSPWEGRLRFQRLSPLLYRLTVLEASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSSTLQSLICSNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSEGKNGVPLLWIKEPHLNYSPTCLEPPVLSIHPGAID"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/1182", 
                    "id": "1182", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "O75054-1", 
            "protein_name": "Immunoglobulin superfamily member 3; IgSF3; Glu-Trp-Ile EWI motif-containing protein 3; EWI-3.", 
            "sequence": {
                "length": 1194, 
                "sequence": "MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIICSNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTCLEPPVLSIHPGAID"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/1182", 
                    "id": "1182", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006233105.1", 
        "ac": "XP_006233105.1", 
        "name": "immunoglobulin superfamily member 3 isoform X3.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K7L2", 
                                "id": "A0A0G2K7L2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032808", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K7L2", 
                                "id": "A0A0G2K7L2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "lacrimal gland development", 
                        "id": "GO:0032808"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 45, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 43
        }, 
        {
            "end_pos": 323, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 321
        }, 
        {
            "end_pos": 420, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 418
        }, 
        {
            "end_pos": 657, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 655
        }, 
        {
            "end_pos": 702, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 700
        }, 
        {
            "end_pos": 844, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 842
        }, 
        {
            "end_pos": 963, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 961
        }, 
        {
            "end_pos": 1075, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1073
        }, 
        {
            "end_pos": 1151, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1149
        }, 
        {
            "end_pos": 1173, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1171
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006233105.1", 
            "id": "XP_006233105.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000023851", 
            "id": "ENSRNOG00000023851", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/EQDFEWS/", 
            "id": "EQDFEWS", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", 
            "id": "IPR003599", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", 
            "id": "IPR007110", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", 
            "id": "IPR013783", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", 
            "id": "IPR036179", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", 
            "id": "IPR013106", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF07686", 
            "id": "PF07686", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/295325", 
            "id": "295325", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1307796", 
            "id": "1307796", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2K7L2", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 134127.0, 
        "chemical_mass": 134127.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K7L2", 
            "name": "Igsf3.", 
            "locus": {
                "end_pos": 203855573, 
                "start_pos": 203768117, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000023851", 
                        "id": "ENSRNOG00000023851", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}