{ "uniprot_canonical_ac": "A0A0G2K6M8-1", "sequence": { "header": "tr|A0A0G2K6M8-1|A0A0G2K6M8_RAT Isoform 1 of DEP domain-containing 5 OS=Rattus norvegicus OX=10116 GN=Depdc5 PE=1 SV=1 CANONICAL=A0A0G2K6M8-1", "length": 1591, "sequence": "MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEVNRASIQQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAGGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKSATEKTKNGRDTSLGAPKESENTLPIQVDYDAYDAQVFRLPGPSRAQRLATCRSVREQENHNRKSASSCDVSSSPSLPSRALPTEEVRSQASDDSSLGKSTNILMIPNPHLHQYEVSSSLGYTSTRDVLENMIEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSRQRDPTHSSAELLELAYHEAAGRHSTSRQPGDSMSLNFSGTEELSVSLLSNSGTGMNPRNQNKDSLEDGVSTSPDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADMDRRDEEGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPSTTVPPPLSSSPLYSRGLVSRNRPEEEGQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFCHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEVHCDIYGDKPRADEDEWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLESTGPPVGKKGTSALSALLEMEASQKSLGEQQTSVHGKSSTQPAENSSVAMTPTYVDSPRKDGAFFMEFVRSPRTASSAFYPQASVDQTAPLVLDSTSLGVSTCQSVDRGNNQTFGNSQNIEQAFPSTGSGDGSSQQHIASSLTSSSTLVEILEAMKHPSTGVQLLSEQKGLSPCCFISAEVVHWLMNNVEGVQTQAMGIDIMQKMLEEQLIAHASGEAWRTFVYGFYFYKIVTDREPERVAMQQPSAPWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTATVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNLGCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFWTNCLEKMHASAP" }, "uniprot_id": "A0A0G2K6M8_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "DEP domain-containing protein 5 isoform X2" ], "uniprotkb": [ "DEP domain-containing 5" ] }, "gene": { "refseq": [ "Depdc5" ], "uniprotkb": [ "Depdc5" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8", "id": "A0A0G2K6M8", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "DEP domain-containing 5." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8#A0A0G2K6M8-1", "isoform_ac": "A0A0G2K6M8-1", "locus": { "end_pos": 83092231, "start_pos": 83218589, "chromosome": "14", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000085788", "id": "ENSRNOT00000085788", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000073874", "id": "ENSRNOP00000073874", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K6M8-1|A0A0G2K6M8_RAT Isoform 1 of DEP domain-containing 5 OS=Rattus norvegicus OX=10116 GN=Depdc5 PE=1 SV=1 CANONICAL=A0A0G2K6M8-1", "length": 1591, "sequence": "MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEVNRASIQQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAGGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKSATEKTKNGRDTSLGAPKESENTLPIQVDYDAYDAQVFRLPGPSRAQRLATCRSVREQENHNRKSASSCDVSSSPSLPSRALPTEEVRSQASDDSSLGKSTNILMIPNPHLHQYEVSSSLGYTSTRDVLENMIEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSRQRDPTHSSAELLELAYHEAAGRHSTSRQPGDSMSLNFSGTEELSVSLLSNSGTGMNPRNQNKDSLEDGVSTSPDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADMDRRDEEGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPSTTVPPPLSSSPLYSRGLVSRNRPEEEGQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFCHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEVHCDIYGDKPRADEDEWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLESTGPPVGKKGTSALSALLEMEASQKSLGEQQTSVHGKSSTQPAENSSVAMTPTYVDSPRKDGAFFMEFVRSPRTASSAFYPQASVDQTAPLVLDSTSLGVSTCQSVDRGNNQTFGNSQNIEQAFPSTGSGDGSSQQHIASSLTSSSTLVEILEAMKHPSTGVQLLSEQKGLSPCCFISAEVVHWLMNNVEGVQTQAMGIDIMQKMLEEQLIAHASGEAWRTFVYGFYFYKIVTDREPERVAMQQPSAPWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTATVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNLGCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFWTNCLEKMHASAP" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8#D4A362-1", "isoform_ac": "D4A362-1", "locus": { "end_pos": 83092231, "start_pos": 83207342, "chromosome": "14", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000067694", "id": "ENSRNOT00000067694", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000061924", "id": "ENSRNOP00000061924", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D4A362-1|A0A0G2K6M8_RAT Computationally mapped isoform of DEP domain-containing 5 OS=Rattus norvegicus OX=10116 GN=Depdc5 PE=1 SV=1 CANONICAL=A0A0G2K6M8-1", "length": 1456, "sequence": "MWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEVNRASIQQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAGGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKSATEKTKNGRDTSLGAPKESENTLPIQVDYDAYDAQVFRLPGPSRAQRLATCRSVREQENHNRKSASSCDVSSSPSLPSRALPTEEVRSQASDDSSLGKSTNILMIPNPHLHQYEVSSSLGYTSTRDVLENMIEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSRQRDPTHSSAELLELAYHEAAGRHSTSRQPGDSMSLNFSGTEELSVSLLSNSGTGMNPRNQNKDSLEDGVSTSPDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADMDRRDEEGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPSTTVPPPLSSSPLYSRGLVSRNRPEEEGQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFCHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEVHCDIYGDKPRADEDEWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLESTGPPVGKKGTSALSALLEMEASQKSLGEQQTSVHGKSSTQPAENSSVAMTPTYVDSPRKASVDQTAPLVLDSTSLGVSTCQSVDRGNNQTFGNSQNIEQAFPSTGSGDGSSQQHIASSLTSSSTLVEILEAMKHPSTGVQLLSEQKGLSPCCFISAEVVHWLMNNVEGVQTQAMGIDIMQKMLEEQLIAHASGEAWRTFVYGFYFYKIVTDREPERVAMQQPSAPWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTATVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNLGCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFWTNCLEKMHASAP" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9639288", "resource": "Reactome", "id": "R-RNO-9639288", "name": "Amino acids regulate mTORC1" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "P61460-1", "protein_name": "GATOR complex protein DEPDC5; DEP domain-containing protein 5.", "sequence": { "length": 1591, "sequence": "MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEINRASIQEDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAGGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKSASEKTKNGRDTSLGTPKESENTLPIQVDYDAYDAQVFRLPGPSRAQRLATCRSVREQENHSRKSASSCDVSSSPSLPSRALPTEEVRSQASDDSSLGKSTNILMIPNPHLHQYEVSSSLGYTSTRDVLENMIEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSRQRDPTHSSAELLELAYHEAAGRHSTSRQPGDSMSLNFSGTEELSVSLLSNSSTGVNPRTQNKDSLEDSVSTSPDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADMDRRDEEGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNTTVPPPLSSSPLYSRGLVSRNRPEEEGQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVDFCHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEVHCDIYGDKPRADEDEWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLEAAGPPVGKKGTSALSALLEMEASQKSLGEQQTTVHGKSSTQPAENSSVAMTPTYVDSPRKDGAFFMEFVRSPRTASSAFYPQASVDQTAPLVLDSTSLGVSTGQPMDRGNNQTFGNSQNIEQAFPSANSGDYSSQQHVASSLTSSSTLVEILEAMKHPSTGVQLLSEQKGLSPCCFISAEVVHWLMNNVEGVQTQAMGIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVMDKEPERVAMQQPSAPWYTAGADDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTATVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNLSCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSVSAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFWTNCLEKMHASAP" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/34718", "id": "34718", "database": "MGI" } ], "organism": "Mus musculus", "tax_id": 10090 }, { "uniprot_canonical_ac": "O75140-10", "protein_name": "GATOR complex protein DEPDC5; DEP domain-containing protein 5.", "sequence": { "length": 1603, "sequence": "MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTTCRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHLHQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLELAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTSPDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKDGAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/34718", "id": "34718", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A0A0G2K6M8/", "id": "A0A0G2K6M8", "database": "OMA" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017454700.1", "ac": "XP_017454700.1", "name": "DEP domain-containing protein 5 isoform X2.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8", "id": "A0A0G2K6M8", "database": "UniProtKB" } ], "name": "GTPase activator activity", "id": "GO:0005096" } ], "total": 1, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8", "id": "A0A0G2K6M8", "database": "UniProtKB" } ], "name": "lysosomal membrane", "id": "GO:0005765" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990130", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8", "id": "A0A0G2K6M8", "database": "UniProtKB" } ], "name": "GATOR1 complex", "id": "GO:1990130" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8", "id": "A0A0G2K6M8", "database": "UniProtKB" } ], "name": "cytosol", "id": "GO:0005829" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8", "id": "A0A0G2K6M8", "database": "UniProtKB" } ], "name": "perinuclear region of cytoplasm", "id": "GO:0048471" } ], "total": 4, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8", "id": "A0A0G2K6M8", "database": "UniProtKB" } ], "name": "negative regulation of TOR signaling", "id": "GO:0032007" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8", "id": "A0A0G2K6M8", "database": "UniProtKB" } ], "name": "cellular response to amino acid starvation", "id": "GO:0034198" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8", "id": "A0A0G2K6M8", "database": "UniProtKB" } ], "name": "intracellular signal transduction", "id": "GO:0035556" } ], "total": 3, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 213, "annotation": "n_glycosylation_sequon", "start_pos": 211 }, { "end_pos": 300, "annotation": "n_glycosylation_sequon", "start_pos": 298 }, { "end_pos": 313, "annotation": "n_glycosylation_sequon", "start_pos": 311 }, { "end_pos": 386, "annotation": "n_glycosylation_sequon", "start_pos": 384 }, { "end_pos": 406, "annotation": "n_glycosylation_sequon", "start_pos": 404 }, { "end_pos": 685, "annotation": "n_glycosylation_sequon", "start_pos": 683 }, { "end_pos": 1064, "annotation": "n_glycosylation_sequon", "start_pos": 1062 }, { "end_pos": 1130, "annotation": "n_glycosylation_sequon", "start_pos": 1128 }, { "end_pos": 1352, "annotation": "n_glycosylation_sequon", "start_pos": 1350 }, { "end_pos": 1367, "annotation": "n_glycosylation_sequon", "start_pos": 1365 }, { "end_pos": 1519, "annotation": "n_glycosylation_sequon", "start_pos": 1517 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017454700.1", "id": "XP_017454700.1", "database": "RefSeq" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9639288", "id": "R-RNO-9639288", "database": "Reactome" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000018144", "id": "ENSRNOG00000018144", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/RMYDLQM/", "id": "RMYDLQM", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "id": "IPR036388", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "id": "IPR036390", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR027244", "id": "IPR027244", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "id": "IPR000591", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00610", "id": "PF00610", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF12257", "id": "PF12257", "database": "Pfam" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13179", "id": "PTHR13179", "database": "PANTHER" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/305464", "id": "305464", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1311535", "id": "1311535", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A0G2K6M8", "disease": [], "mass": { "monoisotopic_mass": 180161.0, "chemical_mass": 180161.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K6M8", "name": "Depdc5.", "locus": { "end_pos": 83089000, "start_pos": 83219464, "chromosome": "14", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000018144", "id": "ENSRNOG00000018144", "database": "Ensembl Gene" } ] } } ] }