{
    "uniprot_canonical_ac": "A0A0G2K658-1", 
    "sequence": {
        "header": "tr|A0A0G2K658-1|A0A0G2K658_RAT Isoform 1 of Carbonyl reductase [NADPH] 1-like  OS=Rattus norvegicus OX=10116 GN=LOC102556347 PE=1 SV=1 CANONICAL=A0A0G2K658-1", 
        "length": 329, 
        "sequence": "MGEGLGLGVHAGSIPNPGPLENRTRKAVPLPPSCRVYPRFFGLRRPFYAHAAMSSDRPVALVTGANKGIGFAIVRDLCRKFLGDVVLTARDESRGHEAVKQLQTEGLSPRFHQLDIDNPQSIRALRDFLLQEYGGLNVLVNNAGIAFKVVDPTPFHIQAEVTMKTNFFGTQDVCKELLPIIKPQGRVVNVSSGMSLRALKSCSPELQQKFRSETITEEELVGLMNKFIEDAKKGVHAKEGWPNSAYGVTKIGVTVLSRIYARKLNEERREDKILLNACCPGWVRTDMTGPEATKSPEEGAETPVYLALLPPGAEGPHGQFVQDKKVEPW"
    }, 
    "uniprot_id": "A0A0G2K658_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "carbonyl reductase [NADPH] 1"
            ], 
            "uniprotkb": [
                "Carbonyl reductase [NADPH] 1-like"
            ]
        }, 
        "gene": {
            "refseq": [
                "LOC102556347"
            ], 
            "uniprotkb": [
                "LOC102556347"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K658", 
                    "id": "A0A0G2K658", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Carbonyl reductase [NADPH] 1-like."
    }, 
    "publication": [
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", 
            "journal": "Nat. Commun.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K658/publications", 
                    "id": "A0A0G2K658", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", 
            "date": "2012", 
            "pmid": "22673903"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K658#M0R3X6-1", 
            "isoform_ac": "M0R3X6-1", 
            "locus": {
                "end_pos": 33863598, 
                "start_pos": 33865811, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000072384", 
                        "id": "ENSRNOT00000072384", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000064050", 
                        "id": "ENSRNOP00000064050", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|M0R3X6-1|A0A0G2K658_RAT Computationally mapped isoform of Carbonyl reductase [NADPH] 1-like  OS=Rattus norvegicus OX=10116 GN=LOC102556347 PE=1 SV=1 CANONICAL=A0A0G2K658-1", 
                "length": 277, 
                "sequence": "MSSDRPVALVTGANKGIGFAIVRDLCRKFLGDVVLTARDESRGHEAVKQLQTEGLSPRFHQLDIDNPQSIRALRDFLLQEYGGLNVLVNNAGIAFKVVDPTPFHIQAEVTMKTNFFGTQDVCKELLPIIKPQGRVVNVSSGMSLRALKSCSPELQQKFRSETITEEELVGLMNKFIEDAKKGVHAKEGWPNSAYGVTKIGVTVLSRIYARKLNEERREDKILLNACCPGWVRTDMTGPEATKSPEEGAETPVYLALLPPGAEGPHGQFVQDKKVEPW"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K658#A0A0G2K658-1", 
            "isoform_ac": "A0A0G2K658-1", 
            "locus": {
                "end_pos": 33812931, 
                "start_pos": 33865811, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000085961", 
                        "id": "ENSRNOT00000085961", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073686", 
                        "id": "ENSRNOP00000073686", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2K658-1|A0A0G2K658_RAT Isoform 1 of Carbonyl reductase [NADPH] 1-like  OS=Rattus norvegicus OX=10116 GN=LOC102556347 PE=1 SV=1 CANONICAL=A0A0G2K658-1", 
                "length": 329, 
                "sequence": "MGEGLGLGVHAGSIPNPGPLENRTRKAVPLPPSCRVYPRFFGLRRPFYAHAAMSSDRPVALVTGANKGIGFAIVRDLCRKFLGDVVLTARDESRGHEAVKQLQTEGLSPRFHQLDIDNPQSIRALRDFLLQEYGGLNVLVNNAGIAFKVVDPTPFHIQAEVTMKTNFFGTQDVCKELLPIIKPQGRVVNVSSGMSLRALKSCSPELQQKFRSETITEEELVGLMNKFIEDAKKGVHAKEGWPNSAYGVTKIGVTVLSRIYARKLNEERREDKILLNACCPGWVRTDMTGPEATKSPEEGAETPVYLALLPPGAEGPHGQFVQDKKVEPW"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:102556347", 
            "resource": "KEGG Pathway", 
            "id": "rno:102556347", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "P16152-1", 
            "protein_name": "Carbonyl reductase [NADPH] 1; 1.1.1.184; 15-hydroxyprostaglandin dehydrogenase [NADP(+)]; 1.1.1.197; Prostaglandin-E(2) 9-reductase; 1.1.1.189; NADPH-dependent carbonyl reductase 1; Prostaglandin 9-ketoreductase; reductase family 21C member 1.", 
            "sequence": {
                "length": 277, 
                "sequence": "MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQW"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/37524", 
                    "id": "37524", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "P48758-1", 
            "protein_name": "Carbonyl reductase [NADPH] 1; 1.1.1.184; 15-hydroxyprostaglandin dehydrogenase [NADP(+)]; 1.1.1.197; Prostaglandin-E(2) 9-reductase; 1.1.1.189; NADPH-dependent carbonyl reductase 1; Prostaglandin 9-ketoreductase.", 
            "sequence": {
                "length": 277, 
                "sequence": "MSSSRPVALVTGANKGIGFAITRDLCRKFSGDVVLAARDEERGQTAVQKLQAEGLSPRFHQLDIDNPQSIRALRDFLLKEYGGLDVLVNNAGIAFKVNDDTPFHIQAEVTMKTNFFGTRDVCKELLPLIKPQGRVVNVSSMVSLRALKNCRLELQQKFRSETITEEELVGLMNKFVEDTKKGVHAEEGWPNSAYGVTKIGVTVLSRILARKLNEQRRGDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVQDKKVEPW"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/37524", 
                    "id": "37524", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "P47727-1", 
            "protein_name": "Carbonyl reductase [NADPH] 1; 1.1.1.184; 15-hydroxyprostaglandin dehydrogenase [NADP(+)]; 1.1.1.197; Prostaglandin-E(2) 9-reductase; 1.1.1.189; 20-beta-hydroxysteroid dehydrogenase; NADPH-dependent carbonyl reductase 1; Prostaglandin 9-ketoreductase.", 
            "sequence": {
                "length": 277, 
                "sequence": "MSSDRPVALVTGANKGIGFAIVRDLCRKFLGDVVLTARDESRGHEAVKQLQTEGLSPRFHQLDIDNPQSIRALRDFLLQEYGGLNVLVNNAGIAFKVVDPTPFHIQAEVTMKTNFFGTQDVCKELLPIIKPQGRVVNVSSSVSLRALKSCSPELQQKFRSETITEEELVGLMNKFIEDAKKGVHAKEGWPNSAYGVTKIGVTVLSRIYARKLNEERREDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPGAEGPHGQFVQDKKVEPW"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/37524", 
                    "id": "37524", 
                    "database": "MGI"
                }
            ], 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248171.1", 
        "ac": "XP_006248171.1", 
        "name": "carbonyl reductase [NADPH] 1.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K658", 
                                "id": "A0A0G2K658", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "oxidoreductase activity", 
                        "id": "GO:0016491"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 24, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 22
        }, 
        {
            "end_pos": 191, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 189
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248171.1", 
            "id": "XP_006248171.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:102556347", 
            "id": "rno:102556347", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000049911", 
            "id": "ENSRNOG00000049911", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/GTENSME/", 
            "id": "GTENSME", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", 
            "id": "IPR036291", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", 
            "id": "IPR002347", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", 
            "id": "IPR020904", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00106", 
            "id": "PF00106", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/102556347", 
            "id": "102556347", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=7631561", 
            "id": "7631561", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2K658", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 36223.0, 
        "chemical_mass": 36223.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K658", 
            "name": "LOC102556347.", 
            "locus": {
                "end_pos": 33865933, 
                "start_pos": 33812662, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000049911", 
                        "id": "ENSRNOG00000049911", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}